Search clinical trials for: [14C] NKTR-118

Total 4126 results

National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

Parkinson's Disease | Atherosclerosis | Cardiomyopathy | Li-Fraumeni Syndrome | Cardiovascular Capacity

United States
Seoul National University Hospital
Seoul National University Bundang Hospital

Completed

Plasmalyte-148 Solution and Blood Coagulation

Blood Coagulation Disorder

Korea, Republic of
James M Noble, MD, MS, CPH, FAAN
National Institute on Aging (NIA)

Recruiting

Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease (ADVISe)

Alzheimer Disease

United States
Washington University School of Medicine
The Foundation for Barnes-Jewish Hospital

Completed

Sex and Obesity: Effects on Heart Failure Study

Heart Failure | Obesity

United States
AbbVie
KU Leuven; Syndesi Therapeutics

Completed

A Single Ascending Oral Dose Study of SDI-118 in Healthy Male Subjects Including an Assessment of Receptor Occupancy and Food Effect

Cognitive Disorders

Belgium
IRCCS San Raffaele

Completed

Prognostic Values of PET Examination With 11 C-Fe_CIT With Voxel-based Analysis Method in Patients With Sporadic Parkonson's Disease and Parkinsonisms (Prot.PD-diagn).

Parkinson Disease
Nektar Therapeutics

Completed

Study to Evaluate the Safety and Efficacy of NKTR-102 in Patients With Metastatic or Locally Advanced Ovarian Cancer

Ovarian Cancer | Tumor

United States, Belgium, United Kingdom
Imperial College London

Recruiting

Quantifying 18kDa TSPO Expression in the Lung in Pulmonary Artery Hypertension (PAH)

Healthy | Pulmonary Arterial Hypertension

United Kingdom
Akiva Mintz

Recruiting

Exploratory Evaluation of [11C]-NOP46

Chronic Pain

United States
IRCCS San Raffaele

Completed

PET Study With 11 C-PIB to Evaluate Amyloid Protein Deposits in Mild Cognitive Disorder, Alzheimer's Disease and Early Frontotemporal Degeneration.

Alzheimer Disease
AstraZeneca

Completed

A PET Study to Determine Biodistribution and Binding Characteristics of [11C]AZ14132516 in Healthy Participants

Healthy Volunteers

Sweden
Bristol-Myers Squibb

Completed

A Study to Evaluate the Safety, Tolerability, Kinetics, Biodistribution and Repeatability of 11C-BMS-986196 After Intravenous (IV) Administration in Healthy Participants and After Repeat IV Administration in Participants With Multiple Sclerosis

Multiple Sclerosis (MS)

United States, United Kingdom
National University Hospital, Singapore

Unknown

Evaluation of 11C-acetate PET Imaging as a Novel Approach to Detecting Pathology in Pulmonary TB

Tuberculosis, Pulmonary

Singapore
Helios Albert-Schweitzer-Klinik Northeim

Completed

Endocuff-assisted Versus Cap-assisted Versus Standard Colonoscopy (EC-Cap-SC)

Colorectal Polyps | Colorectal Adenomas

Germany, Poland
Nektar Therapeutics
Eli Lilly and Company

Completed

A Study of NKTR-358 (LY3471851) in Healthy Participants

Healthy

United States
Saisei Pharma

Completed

Trial Efficacy of Saisei Pharma Dietary Supplements MAF Capsules, 148 mg and M Capsules, 148 mg in Hospitalized COVID-19 Patients (SaiseiCovUKR)

Covid19

Ukraine
University of Aarhus

Completed

Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CT

Primary Sclerosing Cholangitis | Cholestasis | Primary Biliary Cirrhosis

Denmark
Nektar Therapeutics
Eli Lilly and Company

Completed

A Study of NKTR-358 (LY3471851) in Participants With Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

United States
InQpharm Group

Withdrawn

Vasoactive Effects of IQP-AS-118 in Healthy Individuals

Cardiovascular Disease | Blood Flow

Germany
InQpharm Group

Completed

Benefit of IQP-AS-118 on Blood Pressure and LDL-cholesterol

Blood Pressure | Low Density Lipoprotein Cholesterol Level

Germany
Massachusetts General Hospital
Genentech, Inc.

Unknown

Effect of Ocrelizumab on Neuroinflammation in Multiple Sclerosis as Measured by 11C-PBR28 MR-PET Imaging of Microglia Activation

Multiple Sclerosis
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With [18F]AZD4694 and [11C]AZD2184, Candidate PET Ligands for Aβ Amyloid (PET)

Alzheimer's Disease

Sweden
Bausch Health Americas, Inc.
Dow Pharmaceutical Sciences

Completed

Safety and Efficacy of IDP-118 in the Treatment of Plaque Psoriasis

Plaque Psoriasis

United States
Bausch Health Americas, Inc.

Completed

Safety and Efficacy of IDP-118 Lotion in the Treatment of Plaque Psoriasis

Psoriasis

United States
Washington University School of Medicine

Recruiting

Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1

Alzheimer Disease

United States
Davidzon, Guido, M.D.
Weston Havens Foundation

Recruiting

Imaging Synapses With [11C] UCB-J in the Human Brain

Schizophrenia

United States
Peking Union Medical College Hospital

Recruiting

[18F]Florbetazine ([18F]92) for Beta Amyloid PET Imaging in Alzheimer's Disease

Alzheimer's Disease

China
Universitaire Ziekenhuizen KU Leuven
CHDI Foundation, Inc.

Not yet recruiting

Comparison Between [11C]UCB-J and [18F]SynVest-1 PET in HD.

Huntington Disease

Belgium
Christine Elizabeth Edmonds

Withdrawn

Imaging With [11C]Martinostat in Breast Cancer

Breast Cancer

United States
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Brain 5-HT(1A) Receptors Using [(11)C](-)-RWAY

Healthy Volunteers

United States
Nykode Therapeutics ASA
Nektar Therapeutics; Vaccibody AS

Completed

A Study to Evaluate Safety and Efficacy of Multiple Dosing With VB10.NEO and Bempegaldesleukin (NKTR-214) Immunotherapy in Patients With Locally Advanced or Metastatic Cancer (DIRECT-01)

Locally Advanced or Metastatic Solid Tumours

Germany
National Institute of Mental Health (NIMH)

Recruiting

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

Parkinson's Disease | Dementia | ALS | Alzheimer's Disease

United States
Emory University

Completed

Norepinephrine Transporter Availability in PTSD

Posttraumatic Stress Disorder

United States
Nektar Therapeutics
Eli Lilly and Company

Terminated

A Study of LY3471851 in Adult Participants With Moderately to Severely Active Ulcerative Colitis (UC) (INSTRUCT-UC)

Colitis, Ulcerative

Australia, India, United States, Korea, Republic of, Hungary, United Kingdom, Japan, Argentina, Belgium, Brazil, Canada, China, Czechia, France, Georgia, Israel, Latvia, Poland, Romania, Russian Federation, Slovakia, Ukraine
Johns Hopkins University
Precision Molecular

Terminated

Study of [11C]CPPC to Assess the Safety and Tolerability in Patients With ALS

Amyotrophic Lateral Sclerosis

United States
Laboratorios Sophia S.A de C.V.

Withdrawn

Efficacy and Safety of PRO-118 Ophthalmic Solution in Allergic Conjunctivitis (PRO-118)

Conjunctivitis, Allergic | Seasonal Allergic Conjunctivitis | Ocular Itching | Ocular Allergy | Perennial Allergic Conjunctivitis

Mexico
Wuhan Union Hospital, China

Recruiting

The Diagnostic Value of Hybrid PET/MR for Systemic Amyloidosis

PET/MR | Systemic Amyloidosis

China
Johnson & Johnson Consumer Inc. (J&JCI)

Completed

A Study to Evaluate the Efficacy of Investigational OTC Eye Drops

Ophthalmic Solutions

United States
Università Politecnica delle Marche

Unknown

High Protein and High Energy Intakes and Physical Activity on Growth of Extremely Low Birth Weight Infants

Infant, Very Low Birth Weight

Italy
National Institute of Mental Health (NIMH)
Uniformed Services University of the Health Sciences; Suburban Hospital

Completed

Translocator Protein and Inflammation After Traumatic Brain Injury

Healthy | Traumatic Brain Injury (TBI)

United States
Justin Sims

Terminated

11C-acetate for Treatment Response After Radiotherapy for HCC

Hepatocellular Carcinoma

United States
UCB Pharma
Yale University; PRA Health Sciences

Completed

A Brain Imaging Study With Positron Emission Tomography and the Radiotracer [11C]UCB-J to Estimate How Fast Brivaracetam and Levetiracetam Enter the Brain in Healthy Volunteers

Healthy Volunteers

United States
AstraZeneca

Completed

Evaluation of Histamine H3 Receptor Radioligand [11C]AZ12807110 and Histamine H3 Receptor Occupancy of AZD5213 After Oral Administration

Brain Distribution of [11C]AZ12807110 and AZD5213

Sweden
Karolinska University Hospital
University of Copenhagen

Completed

Postoperative Neuroinflammation and Cognitive Dysfunction After Abdominal Surgery (POPE)

Surgery | Anesthesia | Neurogenic Inflammation | Cognitive Disorders
Nektar Therapeutics

Completed

NKTR-255 in Relapsed/Refractory Multiple Myeloma & Non-Hodgkin Lymphoma

Multiple Myeloma | Non-Hodgkin Lymphoma | Indolent Non-Hodgkin Lymphoma

United States
Johns Hopkins University
United States Department of Defense

Not yet recruiting

Study of [11C]CPPC as a Clinical PET Radioligand Biomarker of Microglial Activation in ALS

ALS
M.D. Anderson Cancer Center
Nektar Therapeutics

Recruiting

REStoring lymphoCytes Using NKTR-255* After chemoradiothErapy in Solid Tumors (RESCUE)

Lung Cancer

United States
José A. Luchsinger
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Albert... and other collaborators

Terminated

Brain Imaging in the Diabetes Prevention Program Outcomes Study (DPPOS-Brain)

Alzheimer Disease

United States
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Withdrawn

Concurrent PET D2/D3 Receptor Imaging and fMRI Smoking Cue Reactivity in Smokers

Nicotine Dependence | Smoking Cue Reactivity | Relapse to Smoking

United States
Clinical Hospital Centre Zagreb
Sisters of Mercy University Hospital

Unknown

Normal Saline Vrs Balanced i.v. Fluids in Neurosurgery

Benign Neoplasms | Vascular Malformations, Brain

Croatia

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