Search clinical trials for: [14C]-BIIB091

Total 2912 results

Kadmon Corporation, LLC
Quotient Sciences

Completed

Drug-drug Interaction Between Belumosudil, Itraconazole, Rifampicin, Rabeprazole, and Omeprazole in Healthy Volunteers

Autoimmune Diseases | Drug-drug Interaction | Fibrotic Disease

United Kingdom
University of Minnesota
National Institute of General Medical Sciences (NIGMS)

Completed

Pharmacogenetics of Warfarin Induction and Inhibition

Healthy

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 1 Study to Examine the Drug-Drug Interaction of Ciprofloxacin, Itraconazole, and Rifampin on the Combination of Lumacaftor With Ivacaftor in Healthy Adult Subjects

Cystic Fibrosis

United States
National Cancer Institute (NCI)

Recruiting

Testing the Anti-Cancer Drug Darolutamide in Patients With Testosterone-driven Salivary Gland Cancers

Recurrent Salivary Gland Carcinoma | Metastatic Salivary Gland Carcinoma | Unresectable Salivary Gland Carcinoma | Locally Advanced Salivary Gland Carcinoma

United States
Roswell Park Cancer Institute

Recruiting

Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8

United States
Aligos Therapeutics

Recruiting

A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558

COVID-19

United Kingdom
Bristol-Myers Squibb

Completed

A Study to Assess the Drug Levels of CC-92480 After Coadministration With Rifampin and Itraconazole, and the Drug Levels of Digoxin and Rosuvastatin After Coadministration With CC-92480 in Healthy Participants

Healthy Volunteers

United States
MODAG GmbH
Teva Pharmaceutical Industries, Ltd.; Quotient Sciences; Aptuit

Completed

A Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)

Healthy Volunteers

United Kingdom
Washington University School of Medicine

Completed

Buprenorphine Disposition and CYP3A

Healthy

United States
University of Pittsburgh

Completed

Treatment of Geriatric Bipolar Mood Disorders: A Pilot Study

Bipolar Disorder

United States
Enanta Pharmaceuticals, Inc

Completed

Drug-Drug Interaction Study Between EDP-235, Itraconazole, Carbamazepine and Quinidine in Healthy Subjects.

COVID-19

United States
Ache Laboratorios Farmaceuticos S.A.

Completed

Effectiveness Study of Ketoconazole and Betamethasone to Treat Fungal Infection and Dermatophytosis (DaVinci)

Tinea

Brazil
TherapeuticsMD

Completed

Annovera™ Drug-Drug Interaction Study

Contraception | Women

Canada
Millennium Pharmaceuticals, Inc.

Completed

Pharmacokinetics Study of Oral IXAZOMIB in Participants With Advanced Nonhematologic Malignancies or Lymphoma

Lymphoma | Nonhematologic Malignancies

United States
Fred Hutchinson Cancer Center
National Heart, Lung, and Blood Institute (NHLBI)

Suspended

Total Body Irradiation and Astatine-211-Labeled BC8-B10 Monoclonal Antibody for the Treatment of Nonmalignant Diseases

Non-Malignant Neoplasm

United States
Peking Union Medical College Hospital

Recruiting

Survival Benefits of Statins in Breast Cancer Patients (SBSBC)

Breast Cancer Female

China
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Bortezomib, Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant For High-Risk Stage I or II Multiple Myeloma

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | Plasma Cell Leukemia | Loss of Chromosome 17p | Autologous Hematopoietic Stem Cell Transplant Recipient

United States
Hutchmed

Completed

HMPL-689 Drug Interaction Study With CYP3A Inhibitor/CYP2C9 Inhibitor/CYP3A Inducer/PPI

Relapsed or Refractory Lymphoma

United States
University Hospital, Bordeaux

Completed

Targeting TFPI With Concizumab to Improve Haemostasis in Glanzmann Thrombasthenia Patients: an in Vitro Study (GLAT)

Glanzmann Thrombasthenia

France
LI YAN

Completed

Effect of Azole/Echinocandin Use on Tacrolimus Pharmacokinetics

Kidney Transplant Patients

China
Jazz Pharmaceuticals

Completed

Study to Evaluate the Effect of Rifampicin, Ketoconazole, and Omeprazole on the Pharmacokinetics of Sativex

Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Known Inducer of CYP3A4 | Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Potent Inhibitor of CYP3A4 | Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a CYP2C19...

United Kingdom
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

Observational Evaluation of Infective Risk in Myelodysplastic Syndrome Patients

Myelodysplastic Syndrome

Italy
Amgen

Completed

Study to Evaluate Pharmacokinetics of Prototype Modified-Release Formulations Of Apremilast in Healthy Men

Healthy Volunteers

United States
Seoul National University Hospital

Completed

Evaluation and Validation of Metabolic Markers for the Assessment of CYP3A Activity and Prediction of DDI (CYP3A_weak)

Healthy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Chemotherapy With or Without Strontium-89 in Treating Patients With Prostate Cancer

Prostate Cancer

United States
Fred Hutchinson Cancer Center

Active, not recruiting

Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases

Myasthenia Gravis | Neuromyelitis Optica | Autoimmune Disease | Chronic Inflammatory Demyelinating Polyneuropathy | Lambert Eaton Myasthenic Syndrome | Cerebellar Degeneration | Stiff Person Syndrome | Opsoclonus Myoclonus Syndrome | Neurologic Autoimmune Disease | Autologous Transplant Autoimmune | Multiple... and other conditions

United States
Umm Al-Qura University

Completed

Alter-G Training on Gait and Balance in Diabetic Neuropathy Patients

Diabetic Peripheral Neuropathy

Saudi Arabia
AstraZeneca

Completed

A Phase I Study in Healthy Volunteers to Assess the Effect of Cytochrome3A4 (CYP3A4) Inhibitors (Diltiazem and Itraconazole) on the Pharmacokinetics (PK) of AZD3293 and the Effects of AZD3293 on the Pharmacokinetics of Midazolam, a Cytochrome 3A4 and Cytochrome 3A5 (CYP3A4/CYP3A5) Substrate (AZD3293DDI)

Healthy Volunteers | Pharmacologic Action

United States
The Faculty Hospital Na Bulovce

Completed

Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures

Small Bowel Obstruction | Acute Appendicitis | Perforated Gastroduodenal Ulcer

Czech Republic
Lundquist Institute for Biomedical Innovation at...

Active, not recruiting

Hormonal Mechanisms of Sleep Restriction - Axis Study

Sleep Restriction

United States
The University of Texas Medical Branch, Galveston
National Institute of General Medical Sciences (NIGMS)

Completed

Assessment of Mechanisms of Improved Wound Healing

Burns

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer

Thyroid Gland Undifferentiated (Anaplastic) Carcinoma

United States
Xuanzhu Biopharmaceutical Co., Ltd.

Not yet recruiting

Drug-drug Interaction Study of XZP-3621 Tablet

Healthy Subjects

China
Enanta Pharmaceuticals, Inc
PRA Health Sciences

Completed

Drug-Drug Interaction Study Between EDP-514, Itraconazole, Carbamazepine, and Quinidine in Healthy Subjects

Hepatitis B

United States
Eisai Inc.
Purdue Pharma LP

Completed

Study to Assess the Pharmacokinetic Drug-Drug Interactions of Lemborexant When Coadministered With an Oral Contraceptive, Famotidine, or Fluconazole in Healthy Subjects

Healthy Subjects

United States
M.D. Anderson Cancer Center
Spectrum Pharmaceuticals, Inc

Withdrawn

A Phase Ib Study of Belinostat With RDHAP Chemotherapy (Dexamethasone, Cytarabine, Cisplatinum) in Adults With Relapsed or Refractory Diffuse Large B-cell Lymphoma

Lymphoma
University Hospital, Geneva

Completed

CYP2C9 Activity Evaluated With a Simple Finger Prick

Healthy Volunteers

Switzerland
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer

Stage IV Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma | Castration-Sensitive Prostate Carcinoma

United States
City of Hope Medical Center

Active, not recruiting

Radium Ra 223 Dichloride, Hormone Therapy and Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Prostate Cancer

Prostate Adenocarcinoma

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Completed

Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With RAS Wild-Type Locally Advanced or Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Colorectal Adenocarcinoma | RAS Wild Type

United States
Johann Wolfgang Goethe University Hospital

Unknown

Combination Chemotherapy in Treating Adults With Acute Lymphocytic Leukemia

Leukemia

Germany
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates

Completed

Drug-Drug Interaction Study Between EDP-938, Itraconazole, Rifampin, and Quinidine in Healthy Subjects

RSV Infection

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Calcitriol in Combination With Ketoconazole and Therapeutic Hydrocortisone in Treating Patients With Prostate Cancer

Prostate Adenocarcinoma | Recurrent Prostate Carcinoma | Stage III Prostate Cancer | Stage IV Prostate Cancer

United States
Celgene

Completed

A Phase 1 Open-Label Study to Evaluate the Effect of CYP450 and P-gp Inhibition and Induction on the Pharmacokinetics of Pomalidomide (CC-4047) in Healthy Male Subjects (DDI)

Healthy | Pharmacology, Clinical

United States
Seoul National University Hospital

Completed

Identification and Evaluation of Endogenous Markers for the Assessment of CYP3A Activity

Healthy

Korea, Republic of
Stanford University

Completed

Combination Chemotherapy Plus Low-Dose Radiation Therapy in Treating Patients With Stage I or Stage IIA Hodgkin's Lymphoma

Lymphoma | Hodgkin Disease | Lymphoma, Hodgkin Disease | Lymphoma: Hodgkin

United States
University of Pennsylvania
Children's Hospital of Philadelphia; Crohn's and Colitis Foundation

Completed

Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease (Holiday)

Crohn's Disease

United States
Alexandria University

Completed

The Antibiogram and Outcomes of Antimicrobial Regimens in Microbial Keratitis: A Prospective Cohort Study

Bacterial Keratitis | Fungal Keratitis | Mixed Bacterial and Fungal Keratitis | Microbial Keratitis

Egypt
Celgene

Completed

Study Evaluating the Effects of Food, Cytochrome P450 Inhibition and Induction on the Pharmacokinetics of CC-122

Healthy Volunteer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Chemotherapy Plus Hormone Therapy Versus Androgen Suppression in Treating Patients With Metastatic or Unresectable Prostate Cancer

Prostate Cancer

United States

Search clinical trials for: [14C]-BIIB091

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