Search clinical trials for: [14C]-GSK1278863 solution for IV infusion

Total 257 results

GlaxoSmithKline

Completed

Absorption and Elimination of Radiolabeled Daprodustat

Anaemia

United Kingdom
Theravance Biopharma
GlaxoSmithKline; Hammersmith Medicines Research

Completed

A Phase 1 (Ph1), Single Dose (SD), GSK961081 Absorption, Distribution, Metabolism, and Excretion (ADME) Study in Healthy Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
Basilea Pharmaceutica

Completed

A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy Males

Fungal Infection

United Kingdom
AstraZeneca
Quotient Sciences

Completed

An ADME Study of [14C]AZD0780 in Healthy Male Subjects

Cardiovascular Diseases

United Kingdom
Galapagos NV

Completed

Evaluation of Mass Balance and Absolute Bioavailability of GLPG3970

Healthy

United Kingdom
Basilea Pharmaceutica

Completed

Mass Balance and Pharmacokinetics Study of Derazantinib in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Galapagos NV

Completed

Evaluation of Mass Balance and Absolute Bioavailability of GLPG3667

Healthy

United Kingdom
Galapagos NV

Completed

A Study in Healthy Male Volunteers to Test How the Test Medicine GLPG1972 is Taken up by the Body When Given by Mouth and Into the Vein as an Injection

Healthy

United Kingdom
Bayer

Completed

A Study to Learn How BAY2927088 is Taken up and Handled by the Body in Healthy Male Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

Netherlands
Daiichi Sankyo, Inc.
Quotient Sciences

Completed

A Study to Determine the Absolute Oral Bioavailability of Quizartinib Using a Radiolabeled Microtracer in Healthy Subjects

Healthy Subjects

United Kingdom
Galapagos NV

Completed

A Study in Healthy Male Volunteers to Look at How the Test Medicine GLPG1690 is Taken up by the Body When Given by Mouth and Into a Vein as an Injection

Healthy

United Kingdom
Takeda

Completed

Study to Assess Absolute Bioavailability of TAK-935 (OV935) and to Characterize Mass Balance, Pharmacokinetics, Metabolism, and Excretion of [14C]TAK-935 (OV935) in Healthy Male Participants

Healthy Volunteers

United States
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of [14C]-DK-AH 269 CL in 12 Healthy Male Volunteers

Healthy
Boehringer Ingelheim

Completed

BI 655130 Long-term Treatment in Patients With moderate-to Severe Ulcerative Colitis

Colitis, Ulcerative

Spain, United Kingdom, United States, Belgium, Germany, Italy, Austria, Canada, Japan, Korea, Republic of, Russian Federation, Poland
Galapagos NV

Completed

Evaluation of Mass Balance and Absolute Bioavailability of GLPG1205

Healthy

United Kingdom
Aro Biotherapeutics

Recruiting

Study to Assess the Safety, Tolerability, PK and PD of ABX1100

Healthy

Canada
AstraZeneca

Completed

A Study of MEDI7352 in Painful Osteoarthritis of the Knee

Chronic Pain

Germany, Sweden, United Kingdom
Institut de Recherches Internationales Servier
ADIR, a Servier Group company

Completed

Efficacy and Safety of S95011 in Primary Sjögren's Syndrome Patients

Primary Sjögren's Syndrome

United States, France, United Kingdom, Australia, Germany, Hungary, Spain
Bioblast Pharma Ltd.
Parexel

Completed

A Study to Establish Safety and Maximum Tolerated Dose of IV Trehalose in Healthy Subjects

Healthy Volunteer Subjects

United States
GlaxoSmithKline

Completed

Absorption & Elimination of Radiolabelled GSK2269557

Pulmonary Disease, Chronic Obstructive

United Kingdom
Neurocrine Biosciences
Takeda

Completed

A Study to Assess Absolute Bioavailability (ABA) of TAK-831 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]TAK-831 in Male Healthy Participants

Healthy Volunteers

United States
Bristol-Myers Squibb

Completed

A Study of Milvexian Using an IV Microtracer With Additional Formulation and Food Effect Comparison in Healthy Participants

Healthy Volunteers

United Kingdom
Aquinox Pharmaceuticals (Canada) Inc.
Quotient Clinical

Completed

Phase 1 Absorption Distribution Metabolism and Excretion of AQX-1125 (ADME)

Healthy Volunteer

United Kingdom
AstraZeneca
Quotient Sciences

Completed

Absolute Bioavailability and ADME Study of [14C]AZD9977 in Healthy Male Subjects

Cardiovascular Disease

United Kingdom
argenx

Active, not recruiting

An Open-label Study to Investigate the Clinical Efficacy of Different Dosing Regimens of Efgartigimod IV in Patients With Generalized Myasthenia Gravis (ADAPT NXT)

Generalized Myasthenia Gravis

Georgia, United States, Austria, Belgium, Canada, France, Germany, Italy, Netherlands, Poland, Spain
Millennium Pharmaceuticals, Inc.

Completed

Study to Assess Absolute Bioavailability (ABA) of TAK-906 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]-TAK-906 in Healthy Male Participants

Healthy Volunteers

United States
AstraZeneca
Quotient Sciences

Completed

An ADME Study of [14C]AZD4604 and the Absolute Bioavailability of AZD4604

Asthma

United Kingdom
GlaxoSmithKline
PPD

Terminated

A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor (NEWBORN-1)

Obstetric Labour, Premature

United States, Italy, United Kingdom, Japan, Canada
Takeda
Takeda Development Center Americas, Inc.

Active, not recruiting

Long-term Evaluation on Height and Weight in Patients With MPS II Who Started Treatment at < 6 Years of Age

Hunter Syndrome

United States, Germany, Malaysia, Philippines, Thailand, Dominican Republic, Serbia, Vietnam
GlaxoSmithKline

Completed

Pharmacokinetics (PKs) and Metabolism of Radiolabelled Linerixibat

Cholestasis

United Kingdom
PharmaMar

Completed

Clinical Study of PM01183 in Patients With Acute Leukemia or Relapsed/Refractory Myelodysplastic Syndrome

Acute Leukemia

United States
Boehringer Ingelheim

Recruiting

A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Netherton Syndrome

Netherton Syndrome

Belgium, United Kingdom, Australia, Germany, China, Malaysia, United States, Japan, France, Israel, Bulgaria, Italy, Finland, Switzerland, Netherlands, Portugal
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-9545 Following a Single Oral Dose (Part 1) and to Evaluate the Absolute and Relative Bioavailability of Oral Capsule Formulations of GDC-9545 (Part 2) in Healthy Female Subjects of Non-Childbearing Potential

Healthy Volunteers

United Kingdom
University of British Columbia

Terminated

Effects of Goal-directed Fluid Therapy on Post-operative Outcomes in Children Undergoing Scoliosis Repair (CardioQ-RP)

Scoliosis | Acute Kidney Injury

Canada
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

SAD/MAD Safety and PK Study of QPX9003 (Novel Polymyxin) in Normal Healthy Volunteers (QPX9003)

Bacterial Infections

United States
Boehringer Ingelheim

Completed

Investigation of the Metabolism and Pharmacokinetics of 10 mg [14C] BI 1356 Administered Orally Compared to 5 mg [14C] BI 1356 Administered Intravenously in Healthy Male Volunteers

Healthy
AstraZeneca
Quotient Sciences

Completed

Absolute Bioavailability and ADME Study of Savolitinib in Healthy Male Subjects

Cancer

United Kingdom
AstraZeneca

Completed

A Study to Assess the Absolute Bioavailability of Oral Selumetinib in Healthy Male Volunteers.

Healthy Volunteers Bioavailability Study

United Kingdom
GlaxoSmithKline

Completed

Study to Investigate the Pharmacokinetics (PK), Safety and Tolerability of Retosiban in Healthy Japanese Women

Obstetric Labour, Premature

United States
Takeda

Completed

TAK-385 Phase I Absorption, Distribution, Metabolism, Excretion and Absolute Bioavailability Study

Healthy Volunteers

United Kingdom
Boehringer Ingelheim

Completed

Pharmacokinetics of Talsaclidine After Administration to Healthy Subjects

Healthy
Mayo Clinic

Recruiting

Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia

Lower Urinary Tract Obstructive Syndrome | Renal Failure Congenital | Congenital Renal Anomaly Nos | Renal Agenesis and Dysgenesis

United States
King Edward Medical University

Completed

Comparison of Fluid Resuscitation in Pediatric Burn Patients Using Crystalloids and With Albumin on Day Two.

Burns

Pakistan
AbbVie

Terminated

An Extension Study of ABBV-8E12 in Progressive Supranuclear Palsy (PSP)

Progressive Supranuclear Palsy (PSP)

United States, Australia, Canada, Italy, Japan
Pfizer

Completed

Study to Characterize Absorption, Distribution, Metabolism and Excretion of 14C PF-06651600 and to Evaluate the Absolute Oral Bioavailability and Fraction Absorbed of PF-06651600. (B7981011)

Healthy Volunteers

Netherlands
The University of Queensland
Baxter Healthcare Corporation; Health Research Council, New Zealand; Australian...

Completed

Better Evidence for Selecting Transplant Fluids (BEST-Fluids)

End Stage Kidney Disease | Kidney Transplant; Complications | Delayed Graft Function

Australia, New Zealand
ViiV Healthcare

Completed

Pharmacokinetics and Metabolism of 14 Carbon [14C]-GSK3640254

HIV Infections

United Kingdom
Neupharma Srl
Sintesi Research Srl; Pari Pharma GmbH; Aptuit

Completed

Open-label, Dose-escalation Study to Evaluate the Pharmacokinetics of Inhaled Teicoplanin in Cystic Fibrosis Patients

Cystic Fibrosis

Italy
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of BEA 2180 BR in Healthy Male Volunteers

Healthy
Yonsei University

Completed

The Effects of Dexmedetomidine and Tracheal Intubation on Heart Rate Variability and QTc Interval

Anesthesia, General

Korea, Republic of

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