Search clinical trials for: 13C-Glutamine

Total 2390 results

Robert Fox
Case Western Reserve University

Not yet recruiting

Study Evaluating the Safety of Myeliviz Myelin-Targeting PET Agent

Healthy

United States
Eli Lilly and Company

Completed

A Study of Carbon-14-Labelled [14C] LY3473329 in Healthy Male Participants

Healthy

United Kingdom
Amgen

Completed

Single and Multiple Ascending Dose Study of AMG 133 in Participants With Obesity

Obesity

United States
Eli Lilly and Company

Completed

A Phase I Study of LY3502970 in Healthy Participants

Healthy

United States
Jacobio Pharmaceuticals Co., Ltd.

Completed

Mass Balance Study of [14C]JAB-21822

Mass Balance Study in Healthy Subjects

China
Shandong Luoxin Pharmaceutical Group Stock Co.,...

Completed

Mass Balance and Biotransformation Study of [14C]LXI-15028 in Humans

Healthy Subjects | Pharmacokinetics of 14C-labeled of LXI-15028

China
Stealth BioTherapeutics Inc.

Available

An Intermediate Size Expanded Access Protocol of Elamipretide

Mitochondrial Diseases | Barth Syndrome
Sunshine Lake Pharma Co., Ltd.

Completed

ADME Study of [14C] Antaitavir Hasophate in Healthy Male Subjects

Healthy Male Subjects

China
Merck Sharp & Dohme LLC

Completed

[11C]MK-6884 Positron Emission Tomography (PET) Tracer Validation Trial (MK-6884-001)

Alzheimer's Disease
H. Lundbeck A/S

Completed

A Study Investigating Lu AG06466 in Healthy Men

Healthy Volunteers

United Kingdom
Alkermes, Inc.
University Medical Center Groningen; Amsterdam UMC, location VUmc; QPS Netherlands...

Completed

A Non-therapeutic Feasibility Study of the Radioligand [11C]-UCB-J for Imaging Synaptic Density

Healthy | Alzheimer Disease

Netherlands
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Mass Balance, Pharmacokinetics (PK), Metabolism and Excretion of TAK-954 Containing Microtracer ([14C]-TAK-954) in Healthy Male Participants

Healthy Volunteers

Netherlands
Poxel SA

Completed

Pharmacokinetics and Metabolism of (14C)-Labelled PXL770

Healthy

United Kingdom
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Brain Amyloid Using [11C]MeS-IMPY

Healthy | Alzheimer's Disease

United States
Sanwa Kagaku Kenkyusho Co., Ltd.

Completed

A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-SK-1405

Pruritus

United Kingdom
Motus Therapeutics, Inc.

Completed

Phase 2 Pilot Study to Evaluate the Safety and Efficacy of RM-131 Administered to Females With Anorexia Nervosa

Anorexia Nervosa

United States
Motus Therapeutics, Inc.

Completed

Study to Assess Pharmacodynamics of RM-131 in Patients With Diabetic Gastroparesis

Gastroparesis | Gastrointestinal Motility Disorder | Diabetes Mellitus Complications | Diabetes Mellitus Type 1 and 2

United States
Stealth BioTherapeutics Inc.

Withdrawn

A Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of Bendavia™ (MTP-131) in Patients With Heart Failure

Heart Failure

Bulgaria
Takeda

Completed

Safety, Tolerability and Pharmacokinetics of Escalating Single Doses of TAK-137 in Healthy Participants

Dose Finding Study
ViiV Healthcare
GlaxoSmithKline

Withdrawn

A Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C-GSK2248761 Administered as an Oral Suspension to Healthy Adult Subjects

Infection, Human Immunodeficiency Virus

United States
LG Life Sciences

Completed

Study in Healthy Male Subjects Designed to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C] LC15-0444

Healthy

Korea, Republic of
Fresenius Kabi

Terminated

Hydroxyethyl Starch (130/0.4) for Intravascular Volume Therapy in Liver Transplantation

Intraoperative Complications

China
Eisai Limited

Completed

A Study to Determine the Absolute Bioavailability and the Absorption, Metabolism, and Elimination Properties of Carbon-14 (14C)E7386 in Healthy Male Participants

Healthy Volunteers

United Kingdom
Yale University
National Institute on Drug Abuse (NIDA)

Recruiting

OMAR Opioid Use Disorder

Opioid Use Disorder | Healthy Control

United States
Yale University
National Institute on Drug Abuse (NIDA); National Institute of Mental Health...

Recruiting

Imaging mGluR5 and Synaptic Density in Psychiatric Disorders

Healthy | Bipolar Disorder | Major Depressive Disorder

United States
Sanofi

Completed

Study to Determine Absorption, Metabolism, and Excretion of [14C]-SAR439859, and to Assess Absolute Oral Bioavailability of Amcenestrant (SAR439859), in Healthy Post-menopausal Women

Breast Cancer | Healthy Volunteers

United Kingdom
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Enpatoran Human Mass Balance and Absolute Bioavailability Study

Healthy

Netherlands
University of Minnesota

Completed

Pilot Study of Meat-Borne Carcinogens and Pancreatic Cancer

Pancreatic Cancer

United States
Yale University
National Institute of Neurological Disorders and Stroke (NINDS)

Not yet recruiting

Imaging Depression in Parkinson's Disease

Parkinson's Disease | Major Depressive Disorder
University of Pennsylvania

Recruiting

Neuroinflammation Imaging in AD

Alzheimer Disease | Healthy Volunteer

United States
Hoffmann-La Roche

Completed

Open Label, Adaptive, Parallel Group PET Study Using RO7017773 And [11C] RO15-4513

Autism Spectrum Disorder

United Kingdom
AstraZeneca
Karolinska Institutet, Quintiles IMS

Completed

AZD1390 Administration of a Microdose [11C]AZD1390 to Healthy Volunteers

Healthy Volunteer Male Subjects

Sweden
Chang Gung Memorial Hospital

Completed

Long-Term Vesicular Monoamine Transporter II Imaging and Clinical Assessment of Parkinson's Disease Progression

Parkinson Disease
Chang Gung Memorial Hospital

Completed

Positron-Emission Tomography With Vesicular Monoamine Transporter Ligand ([18F]-DTBZ) In Healthy Elderly And Young Subjects

Healthy
Motus Therapeutics, Inc.
Mayo Clinic

Completed

Effect of Relamorelin on Satiation, Gastric Volume, Gastric Accommodation and Distal Gastric Function in Healthy Volunteers

Gastric Motility

United States
Biogen

Completed

Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of BIIB061 in Healthy Adult Volunteers Including Absolute Bioavailability and Food Effect

Healthy

United States
AstraZeneca

Completed

Study to Assess the Distribution, Metabolism and Excretion of [14C]AZD6765 After a Single-Dose Intravenous Administration (AZD6765)

Major Depressive Disorder

United Kingdom
Lexicon Pharmaceuticals

Completed

An Open-label Study to Evaluate the Absorption, Metabolism, and Excretion of [14C]-Telotristat Etiprate in Males (LX1606-104)

Carcinoid Syndrome

United Kingdom
Molecular Insight Pharmaceuticals, Inc.

Terminated

Phase I Safety and Dosimetry Study in Patients With Confirmed Metastatic Melanoma

Metastatic Melanoma

United States
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With [11C]AZ12713580 to Determine Central mGluR5 Receptor Occupancy of AZD2066 (PET)

Healthy

Sweden
Stealth BioTherapeutics Inc.

Completed

Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of Intravenous (IV) Infusion of MTP-131 (Bendavia™) in Healthy Adults

Healthy

United States
University of Wisconsin, Madison

Completed

Vitamin A Kinetics and Mathematical Modeling in American Women

Vitamin A Kinetics

United States
University of California, San Francisco
National Cancer Institute (NCI); National Institute for Biomedical Imaging...

Recruiting

Hyperpolarized Pyruvate (13C) MR Imaging in Monitoring Patients With Prostate Cancer on Active Surveillance

Prostate Cancer | Prostate Adenocarcinoma

United States
American University
Children's National Research Institute

Completed

The Potential of a Low Glutamate Diet as a Treatment for Pediatric Epilepsy

Randomized Controlled Trial | Refractory Epilepsy | Diet Intervention | Epilepsy in Children | Epilepsy in Youth

United States
Yanzhao

Recruiting

Effects of Oral Care With Glutamine on Oral Health, Oral Flora and Incidence of Pneumonia After Neurosurgery With Microbiome Analysis

Pneumonia | Oral Mucositis

China
University of Virginia
National Institute of Allergy and Infectious Diseases (NIAID)

Withdrawn

HIAS II - Study of Nutritional Supplementation in Hospitalized Children With Persistent Diarrhea or Malnutrition

Diarrhea, Malnutrition | Other Nutritional Deficiencies
Rahul Aggarwal
National Cancer Institute (NCI)

Recruiting

Magnetic Resonance Imaging (MRI) With Hyperpolarized Pyruvate (13C) as Diagnostic Tool in Advanced Prostate Cancer

Prostate Cancer | Advanced Prostate Carcinoma

United States
University of Texas Southwestern Medical Center

Active, not recruiting

Hyperpolarized Carbon 13-Based Metabolic Imaging to Detect Radiation-Induced Cardiotoxicity

Thoracic Cancer | Left Sided Breast Cancer

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of [11C]JNJ-42491293, a Possible PET Ligand for the mGlu2 Receptor, in Healthy Adult Volunteers

Healthy
American University
Georgetown University; United States Department of Defense

Completed

Glutamate Neuro-Excitotoxicity in GWI (GWI)

Gulf War Syndrome

United States

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