Search clinical trials for: 13C-Methacetin

Total 1937 results

Hoffmann-La Roche

Completed

Mass Balance and Absolute Bioavailability Study of RO7049389 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Virginia Commonwealth University
Oridion

Completed

Development of a Breath Test for Monitoring Patients With Liver Disease

Fatty Liver | Cirrhosis

United States
Hadassah Medical Organization

Withdrawn

Follow Up of Patients Chronic Hepatitis B (CHB) Treated With Sebivo Using the 13C Methacetin Breath Test

Chronic Hepatitis B

Israel
Meridian Bioscience, Inc.

Completed

BREATHID Octanoate Breath Test With or Without Methacetin Breath Test for Correlation With Biopsy in NASH

Non-Alcoholic Steatohepatitis

United States, France, Belgium, United Kingdom
University of Texas Southwestern Medical Center
Medical University of South Carolina; National Institute of Diabetes and Digestive... and other collaborators

Completed

13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF (ALFSG-MBT)

Acute Liver Failure

United States
Humedics GmbH

Completed

Fast-track LiveR: Study for the Early Identification of Low-risk Patients After Partial Liver Resection by the LiMAx-test

Liver Failure

Germany
University of Zurich

Completed

13C Trioctanoate Breath Test as a Measurement of Gastric Fat Volume Emptying (13CTriOBT)

Healthy

Switzerland
Hoffmann-La Roche

Completed

A Study to Determine the Excretion Balance, Pharmacokinetics, Metabolism and Absolute Oral Bioavailability of a Single Oral Dose of [14C]-Labeled Idasanutlin and an Intravenous Tracer Dose of [13C]-Labeled Idasanutlin in a Single Cohort of Participants With Solid Tumors (Malignancies)

Solid Tumors

Hungary
Meridian Bioscience, Inc.
Conatus Pharmaceuticals

Completed

Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14

Cirrhosis | Portal Hypertension | NASH - Nonalcoholic Steatohepatitis

France
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Dysregulation of Glutamine Activity in the Pathogenesis of Multiple Myeloma

Monoclonal Gammopathy of Undetermined Significance | Plasma Cell Myeloma

United States
Meridian Bioscience, Inc.
Conatus Pharmaceuticals

Terminated

Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-17

Decompensated Cirrhosis

United States
Robert Bok, MD, PhD
National Cancer Institute (NCI); National Institute for Biomedical Imaging... and other collaborators

Recruiting

Hyperpolarized 13C Pyruvate as a Biomarker in Advanced Solid Tumors

Advanced Solid Tumor

United States
University of Wisconsin, Madison

Recruiting

In Vivo Metabolic Profiling of CLL (Chronic Lymphocytic Leukemia)

Chronic Lymphocytic Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

Parkinson's Disease | Atherosclerosis | Cardiomyopathy | Li-Fraumeni Syndrome | Cardiovascular Capacity

United States
Chang Gung Memorial Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Hyperpolarized 13C Pyruvate MRI for Early Immune Evaluation in Cervical Cancer Patients at Baseline and CCRT Therapy

Cervical Cancer

Taiwan
Meridian Bioscience, Inc.

Completed

Assessing Portal Hypertension With Methacetin Breath Test

Patients With Compensated Liver Cirrhosis

United States, France, Switzerland, Spain
Robert Flavell, MD, PhD
Bristol-Myers Squibb; U.S. Army Medical Research Acquisition Activity

Recruiting

Magnetic Resonance (MR) Imaging With Hyperpolarized Bicarbonate (13C) to Measure Tissue pH in Prostate Cancer

Prostate Cancer | Localized Prostate Carcinoma

United States
Meridian Bioscience, Inc.
Bristol-Myers Squibb

Completed

Companion Protocol for ¹³C-Methacetin Breath Tests in BMS: NCT03486899, NCT03486912 Referenced Trials

NASH - Nonalcoholic Steatohepatitis

United States
Northwestern University

Terminated

Methacetin Breath Test in Patients With Liver Disease Secondary to Heart Disease (MBT+Fontan)

Dilated Cardiomyopathy | Tricuspid Atresia

United States
NCIC Clinical Trials Group

Completed

Liposomal Lurtotecan Plus Cisplatin in Treating Patients With Advanced or Metastatic Solid Tumors

Head and Neck Cancer | Ovarian Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific

Canada
Institute of Liver and Biliary Sciences, India

Completed

Role of 13C Methacetin Breath Test in Predicting Prognosis Among Patients With Acute or Acute on Chronic Liver Failure (ACLF).

Acute Liver Failure | Acute on Chronic Liver Failure

India
University of Texas Southwestern Medical Center
National Cancer Institute (NCI); Howard Hughes Medical Institute

Recruiting

An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy

Kidney Cancer | Renal Cell Carcinoma | Urothelial Carcinoma | Hereditary Leiomyomatosis and Renal Cell Cancer | Metastatic Urothelial Carcinoma | Chromophobe Renal Cell Carcinoma | Papillary Renal Cell Carcinoma | HLRCC | Clear Cell Carcinoma | Metastatic Kidney Cancer | Fumarate Hydratase Deficiency | Succinate...

United States
University of Michigan

Completed

An Exploratory Study of 18F-Labeled Hydroxyphenethylguanidines in Heart Failure Patients

Cardiomyopathy

United States
Loma Linda University

Terminated

Non-invasive Clinical Imaging of Cerebral Metabolism Following Brain Injury Using 13C Magnetic Resonance Spectroscopy.

Traumatic Brain Injury
Meridian Bioscience, Inc.

Completed

BreathID 13C-Methacetin Breath Test for Detecting Cirrhosis (MBT)

Chronic Liver Disease

United States, Israel
Virginia Commonwealth University
Meridian Bioscience, Inc.

Completed

Use of Methacetin Breath Test to Predict Liver Failure in Patients With Cirrhosis

Cirrhosis

United States, Israel
University Hospital Birmingham NHS Foundation Trust
Pancreatic Cancer UK

Recruiting

The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study) (DETECTION)

Pancreatic Exocrine Insufficiency

United Kingdom
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety and Pharmacokinetic Study of C13-URA in Healthy Volunteers

Gastroparesis

United States
The Third Xiangya Hospital of Central South University

Completed

Related Factors of Hp Infection in Physical Examination and Community Population in Hunan Province

Helicobacter Pylori Infection

China
Zhen Wang, MD
American Cancer Society, Inc.

Recruiting

Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Renal Tumors

Renal Cell Cancer | Kidney Neoplasm | Benign Kidney Neoplasm

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Recruiting

Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma

United States
Erasmus Medical Center

Completed

Chronic Mesenteric Ischemia Breath Testing

Chronic Mesenteric Ischemia

Netherlands
KU Leuven

Completed

Determination of the Bioavailability of Short Chain Fatty Acids in Healthy Humans

Short Chain Fatty Acids Bioavailability

Belgium
Meridian Bioscience, Inc.

Completed

MBT Versus HVPG in Identifying Responders to Portal Hypertension Therapy

Bleeding | Cirrhosis | Portal Hypertension | Chronic Liver Disease | Esophageal Varices

Israel
Ivan de Kouchkovsky, MD
National Cancer Institute (NCI); American Cancer Society, Inc.; National Institute...

Recruiting

Pilot Study of (MR) Imaging With Pyruvate (13C) to Detect High Grade Prostate Cancer (pyruvate)

Prostate Cancer

United States
British Columbia Cancer Agency
University of Victoria; University of Texas Southwestern Medical Center; Van...

Recruiting

13C-Glucose Tracing of Tumour and T Cells in the Ascites of Ovarian Cancer Patients. (iMETABO)

Ovarian Cancer | Ascites

Canada
University of Lausanne

Completed

Fructose-induced Intestinal de Novo Lipogenesis (FIDNL)

Obesity

Switzerland
Chang Gung Memorial Hospital
National Science and Technology Council

Not yet recruiting

Hyperpolarized 13C MRI for Cancer Immunotherapy (DNPSPIO)

Cervical Cancer | Gynecologic Cancer | Ovarian Cancer | Endometrial Cancer

Taiwan
University of Texas Southwestern Medical Center

Recruiting

UTSW HP [13-C] Pyruvate Injection in HCM (HPHCM)

Duchenne Muscular Dystrophy | Becker Muscular Dystrophy | Dilated Cardiomyopathy | Cardiomyopathy, Hypertrophic | Heart Failure With Reduced Ejection Fraction | Cardiac Sarcoidosis | Heart Failure With Preserved Ejection Fraction

United States
University of Texas Southwestern Medical Center

Recruiting

Metabolic Characteristics of Brain Tumors Using Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopic Imaging (MRSI) (HPCIM)

Brain Tumor Adult

United States
Rahul Aggarwal
National Cancer Institute (NCI)

Terminated

Magnetic Resonance (MR) Imaging With Hyperpolarized Pyruvate (HP) (13C) in Castration-Resistant Prostate Cancer (MR)

Prostate Cancer

United States
Susan Chang
National Cancer Institute (NCI)

Active, not recruiting

Hyperpolarized Carbon-13 (13C) Pyruvate Imaging in Patients With Glioblastoma

Glioblastoma Multiforme (GBM)

United States
Université de Sherbrooke
Healthy Aging Research Network

Completed

Metabolism of Omega-3 and Omega-6 During Healthy Aging

Healthy Volunteers
University of Florida

Completed

13C-Pyruvate Breath Test (PBT)

Healthy

United States
University of California, San Francisco
GE Healthcare

Completed

Hyperpolarized Pyruvate Injection in Subjects With Prostate Cancer

Prostate Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy

Thyroid Gland Carcinoma

United States
University of Texas Southwestern Medical Center

Enrolling by invitation

Imaging of Traumatic Brain Injury Metabolism Using Hyperpolarized Carbon-13 Pyruvate (HPTBI)

Traumatic Brain Injury

United States
University of Texas Southwestern Medical Center

Enrolling by invitation

Using Hyperpolarized [1-13C]Pyruvate to Detect Cardiotoxicity (HPCardiotox)

Breast Neoplasms

United States
Hadassah Medical Organization
Meridian Bioscience, Inc.

Unknown

¹³C-Methacetin Breath Test (MBT) Methodology Study

Cirrhosis | Healthy Subjects | Chronic Liver Disease

Israel
Mayo Clinic
Takeda Pharmaceuticals International, Inc.

Completed

Biomarkers for Intestinal Permeability in Patients With Constipation

Irritable Bowel Syndrome | Intestinal Diseases | Constipation

United States

Search clinical trials for: 13C-Methacetin

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