Search clinical trials for: 1st line treatment

Total 16666 results

London School of Hygiene and Tropical Medicine
Liverpool School of Tropical Medicine; Medical Research Council Unit, The Gambia and other collaborators

Completed

Intermittent Preventive Treatment Versus Scheduled Screening and Treatment of Malaria in Pregnancy (IPTp_IST)

Pregnancy | Malaria | Anaemia

Burkina Faso, Ghana, Gambia, Mali
Tibotec BVBA

Completed

A Study to Determine the Relative Oral Bioavailability of Single Dose Administration of TMC207, Under Fed and Fasted Conditions in Healthy Participants

Healthy
AstraZeneca
Parexel

Completed

A Study to Assess the Drug Absorption Into the Blood After Administration of 3 Doses of AZD5718

Coronary Artery Disease

United Kingdom
Pfizer

Completed

A Study To Estimate The Time Course Of PF-00241939 Concentration In The Blood Following Dosing By Oral Inhalation From Dry Powder Inhalers. (B0871002)

Healthy

Singapore
Seoul National University Hospital

Completed

Comparison of Hyperemic Efficacy Between Central and Peripheral Adenosine Infusion for Fractional Flow Reserve (FFR) Measurement

Myocardial Ischemia | Coronary Artery Disease

Korea, Republic of
ViiV Healthcare
GlaxoSmithKline; Pharmaceutical Product Development (PPD), Inc

Completed

To Assess the Relative Bioavailability (BA) of TRIUMEQ® and Dolutegravir and Lamivudine (DTG/3TC) Pediatric Dispersible Tablet Formulations in Healthy Volunteers

HIV Infections

United States
Chiesi Farmaceutici S.p.A.

Terminated

Efficacy and Safety of CHF 6532 in Patients With Uncontrolled Severe Eosinophilic Asthma (PERSEA)

Asthma; Eosinophilic

Bulgaria
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Psychoeducational and Behavioral Strategies in Reducing Distress and Anxiety in Patients With Multiple Myeloma and Their Family Caregivers

Multiple Myeloma

United States
Children's National Research Institute

Recruiting

T CELL THERAPY OPPOSING NOVEL COVID-19 INFECTION IN IMMUNOCOMPROMISED PATIENTS (TONI)

SARS-CoV-2 Infection

United States
Catherine Bollard
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Recruiting

HIV Antigen-specific T-cells Targeting Conserved Epitopes (HST-NEETs) BMTCTN1903 (BMTCTN1903)

HIV Associated Lymphoma

United States
The HIV Netherlands Australia Thailand Research...
National Nanotechnology Center (NANOTEC), The National Science and Technology...

Terminated

Microneedles for Diagnosis of LTBI

Latent Tuberculosis

Thailand
Hadassah Medical Organization
Tel Aviv University

Completed

Muscle Activity of the Upper Limb Between Task-Specific and Robot Assisted Training Among Individuals Post Stroke

Stroke

Israel
Viveve Inc.

Completed

Viveve Geneveve Treatment of the Vaginal Introitus to Evaluate Safety and Efficacy (VIVEVE II)

Female Sexual Dysfunction

United States, Canada
Brno University Hospital

Not yet recruiting

The Influence of Blood Sampling Technique on the Total Amount of Blood Collected for Laboratory Testing Critically Ill Pediatric Patients (PEDPBM)

Iatrogenic Anaemia

Czechia
West China Hospital

Terminated

Lateral Lymph Node Dissection After Neoadjuvant Chemo-radiation in Advanced Low Rectal Cancer

Rectal Cancer

China
Manchester University NHS Foundation Trust
Baxter Healthcare Corporation; Manchester Metropolitan University

Completed

Comparison of MCO HD on Markers of Vascular Health Compared With On-Line Haemodiafiltration (MoDal)

Cardiovascular Diseases | Inflammation | End Stage Renal Disease

United Kingdom
Medtronic - MITG

Completed

Controlled Acute Hypoxia Study Comparing Pulse Oximetry to Arterial Blood Samples During Motion

Healthy | Hypoxia

United States
Karolinska Institutet

Completed

Internet-delivered Cognitive Behavioral Therapy (CBT) for Health Anxiety (Ha1b)

Hypochondriasis

Sweden
Centre for Addiction and Mental Health
University of British Columbia; Brain Canada; Ontario Shores Centre for Mental...

Active, not recruiting

Efficacy of Convulsive Therapies for Bipolar Depression (CORRECT-BD)

Bipolar Disorder | Bipolar Depression | Bipolar I Disorder | Bipolar II Disorder

Canada
NorthSea Therapeutics B.V.

Recruiting

A Study of NST-6179 in Adult Subjects With Intestinal Failure-Associated Liver Disease (IFALD).

Intestinal Failure Associated Liver Disease

United States
Akdeniz University

Completed

The Effect of Telephone Symptom Triage Protocols in Patients With Cancer Therapy (TeleTRIAGE)

Cancer | Self Efficacy

Turkey
Massachusetts General Hospital
National Institute of Mental Health (NIMH)

Completed

Therapy Targeting Depression and HIV Treatment Adherence (The TRIAD Study)

Depression | HIV Infections | HIV

United States
Shire

Completed

FST-100 in the Treatment of Acute Adenoviral Conjunctivitis

Acute Adenoviral Conjunctivitis

United States, India
Guang'anmen Hospital of China Academy of Chinese...

Recruiting

Survival Benefit of Compound Kushen Injection in the Treatment of Advanced Colorectal Cancer

Advanced Colorectal Carcinoma

China
National Institute of Diabetes and Digestive and...
Vidacare Corporation

Withdrawn

EZIO Compared to Central Venous Lines for Emergency Vascular Access

Catheters, Indwelling | Central Venous Line | Intraosseous Needle

United States
North Bristol NHS Trust

Completed

GDNF in ideopathicParkinsons Disease

Idiopathic Parkinson Disease
Southern Illinois University
American Lung Association

Completed

Effectiveness of the American Lung Association Reactive Anti-Smoking Telephone Help Line in Illinois (QUITLINE)

Smoking

United States
Laboratoires FILLMED

Completed

Evaluation of the Efficacy and Safety of Three Injectable Hyaluronic Acid-based Fillers: Art Filler® Fine Lines, Art Filler® Universal and Art Filler® Lips (AF4)

Loss of Face Volume

France
Altamira Medica Ltd.

Completed

Efficacy and Safety of AM-301 on Allergic Symptoms of Perennial Allergic Rhinitis Sufferers

Rhinitis, Allergic | Perennial Allergic Rhinitis

Canada
Biogen

Completed

New Formulation and Food Effect Study of BIIB074

Trigeminal Neuralgia (TN) | Other Neuropathic Pain

United States
Pfizer

Completed

A Study Estimating The Time Course Of PF-04764793 In The Blood Following Dosing By Oral Inhalation From Dry Powder Inhalers

Healthy

Singapore
Fundació Sant Joan de Déu
Swing Therapeutics, Inc.

Not yet recruiting

Self-guided Acceptance and Commitment Therapy-based Digital Smartphone Application for Management of Fibromyalgia (SMART-FM-SP)

Fibromyalgia

Spain
Abbott Medical Devices

Completed

Atrial Fibrillation Management in Congestive Heart Failure With Ablation (AMICA)

Heart Failure | Persistent Atrial Fibrillation | ICD

Germany, Hungary, Spain
Children's National Research Institute

Recruiting

Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts (ATLANTIC)

Viral Infection | Hematopoietic Stem Cell Transplantation (HSCT) | Primary Immunodeficiency Disorders (PID)

United States
Steba Biotech S.A.

Completed

Safety and Tolerability Study Using WST11 In Patients With Localized Prostate Cancer

Prostate Cancer

United States
Yale University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

CBT for Anxiety in Children With Autism

Anxiety | Autism Spectrum Disorder

United States
Uppsala University

Completed

Survival After Surgical Treatment of Axis Fractures in Elderly

Spinal Fractures
Nanfang Hospital, Southern Medical University

Recruiting

Research on the Mechanisms of Treatment Non-response in Inflammatory Bowel Disease Based on Multi-omics Technology

Inflammatory Bowel Diseases

China
Cancer Research UK

Completed

AST-VAC2 Vaccine in Patients With Non-small Cell Lung Cancer

Advanced Non-small Cell Lung Cancer

United Kingdom
University of Kiel
Institut National de la Santé Et de la Recherche Médicale, France; Aarhus University... and other collaborators

Completed

DOLORisk: Research on Risk Factors and Determinants for Neuropathic Pain

Neuropathic Pain

Germany
M.D. Anderson Cancer Center
National Institute of Dental and Craniofacial Research (NIDCR)

Active, not recruiting

Neuropathic Pain in Head and Neck Cancer

Head and Neck Cancer

United States
University of Zurich

Unknown

Circadian Changes of the Hypothalamic Activity in Patients Suffering From Cluster Headache

Cluster Headache

Switzerland
Duke University
American Cancer Society, Inc.

Completed

Pain Coping Skills for Colorectal Cancer Survivors

Colorectal Cancer

United States
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Not yet recruiting

Immediate Versus Delayed Treatment With Azathioprine or Rituximab in Anti-MOG Antibodies Associated Acute Demyelinating Syndromes in Children: a Randomized Controlled Clinical Trial (IDAR)

Acute Demyelinating Syndrome

France
National University, Singapore

Completed

Comparison of Different Weight Loss Diets With Different Protein Content

Insulin Resistance | Weight Loss

Singapore
Piramal Healthcare Canada Ltd

Completed

Follow-Up Study Evaluating The Long Term Safety and Efficacy of BST-CarGel and Microfracture Repair of the Knee

Knee Injuries

Spain, Canada
Brainsway

Completed

Evaluation of Deep Transcranial Magnetic Stimulation (DTMS) With the H-ADD Coil as an Aid to Smoking Cessation.

Smoking Cessation

United States, Canada, Israel
Lithuanian Sports University
Kappa Bioscience AS; LSMU Kauno ligonine

Not yet recruiting

Vitamin K2 Supplements for Muscle Recovery (Recovery)

Cachexia | Muscle Atrophy

Lithuania
Lebanese American University
Omicron Pharmaceuticals

Completed

Vitamin K2 Supplementation and Arterial Stiffness in the Renal Transplant Population (The KING Trial) (KING)

Arterial Stiffness | Vitamin K2 Deficiency

Lebanon
Japan Heart Foundation

Completed

Japan Morning Surge-1 Study

Hypertension

Japan

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