Search clinical trials for: 2% OPC-12759 ophthalmic suspension

Total 393 results

Alfred E. Tiefenbacher (GmbH & Co. KG)

Completed

Equivalence Study of Dorzolamide 2% Eye Drops Solution

Ocular Hypertension | Open Angle Glaucoma

Germany
Chiesi Farmaceutici S.p.A.

Terminated

Efficacy of Nebulized Beclomethasone Dipropionate (BDP) in the Treatment of Moderate Croup

Croup

Italy
Boehringer Ingelheim

Completed

Meloxicam [Mobic] in Juvenile Rheumatoid Arthritis (JRA)

Arthritis, Juvenile Rheumatoid

United States, Brazil, Mexico, Ukraine
Duke University

Terminated

Pilot Study of Interferon Alfa for Patients Who Have Received Cancer Vaccines

Cancer
ImmunoGen, Inc.

Not yet recruiting

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Recurrent Ovarian Cancer | Folate Receptor-Alpha Positive

United States, Spain, Australia, Belgium, Canada, France, Ireland, Italy
Milton S. Hershey Medical Center

Completed

Continuous Administration of Oral Contraceptive, Primary Dysmenorrhea (Dysmenorrhea)

Dysmenorrhea

Croatia
Bausch & Lomb Incorporated

Completed

Evaluation of the Safety and Pharmacokinetics of Brimonidine Tartrate 0.025%/Ketotifen Fumarate 0.035% Combination Ophthalmic Solution

Allergic Conjunctivitis

United States
Alcon Research

Completed

Evaluation of Intraocular Pressure Using Simbrinza™ in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Oculis

Completed

OCS-01 in Treating Inflammation and Pain in Post-cataract Patients (SKYGGN)

Pain, Postoperative | Inflammation Corneal

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
Otsuka America Pharmaceutical

Completed

STAT Inhibitor OPB-111077, Decitabine and Venetoclax in Treating Patients With Acute Myeloid Leukemia That Is Refractory, Relapsed or Newly Diagnosed and Ineligible for Intensive Chemotherapy

Acute Myeloid Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia

United States
Ocular Therapeutix, Inc.

Completed

A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract

Cataract

United States
Merck Sharp & Dohme LLC
Integrated Therapeutics Group

Withdrawn

Effects of Low-dose Maintenance Peg Interferon Alfa-2b Therapy Versus Supportive Care in Patients With Cirrhotic Hepatitis C With HIV (Study P04371)

Liver Cirrhosis | HIV Infections | Hepatitis C
Kyushu University

Unknown

PEG-IFN Plus Ribavirin Combination Therapy for Older Patients

Hepatitis C Virus

Japan
Bristol-Myers Squibb

Completed

BMS-790052 (Daclatasvir) Plus Peg-Interferon Alfa-2a and Ribavirin in Treatment-Naive Black/African-Americans, Latinos and White/Caucasians With Hepatitis C

Hepatitis C

United States, Puerto Rico
LENZ Therapeutics, Inc
ORA, Inc.

Completed

Phase 3 Efficacy Study of LNZ101 for the Treatment of Presbyopia (CLARITY)

Eye Diseases | Presbyopia | Miosis | Near Vision

United States
Allergan

Completed

Safety and Efficacy of Triple Combination Therapy in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma

India
José Antonio Carrion
Instituto de Salud Carlos III

Completed

HBsAg Loss Adding Pegylated Interferon in HBeAg-negative Patients

Chronic Hepatitis B (HBeAg-negative)
Novartis Pharmaceuticals

Completed

Additive Effect of Twice-daily Brinzolamide 1%/Brimonidine 0.2%Combination as an Adjunctive Therapy to Travoprost in Patients With Normal Tension Glaucoma

Glaucoma

Korea, Republic of
Myrexis Inc.

Terminated

A Study to Assess the Long-term Efficacy (24 Weeks) of MPC-4326 in Combination With a 2-3 Drug OBR Relative to the Efficacy of a 3-4 Drug ARV Regimen in Treatment Experienced HIV-1 Infected Subjects Who Are Failing Current Antiretroviral Therapy

HIV Infections

Canada, United States
Gilead Sciences

Completed

Evaluate Efficacy, Safety and PK of Adefovir Dipivoxil Liquid Suspension in Patients With Chronic Hepatitis B

Chronic Hepatitis B

United States
Chinese University of Hong Kong
Hoffmann-La Roche

Completed

Treatment With Peginterferon Alfa-2a (40 KD) of Chronic Hepatitis B Patients, Who Have Failed Anti-viral Treatment

Chronic Hepatitis B

China
Hospices Civils de Lyon

Unknown

RIBAJUSTE Clinical Trial Investigating the Efficacy and Safety of Dose Adaptation of Ribavirin (RIBAJUSTE)

Chronic Hepatitis C

France
Tianjin Medical University

Recruiting

Clinical Study of High Concentration Ganciclovir Eye Drops in the Treatment of Cytomegalovirus Retinitis

Cytomegalovirus Retinitis | Ganciclovir Eye Drops

China
Vectura Limited

Completed

A Comparison of VR647 and Conventionally Nebulized Budesonide in Healthy Volunteers and Adult Asthma Subjects

Asthma

United States
Nobelpharma

Completed

NPC-12G Gel 0.2% Sirolimus PK Bridging Study

Bioavailability Study

United States
Manchester University NHS Foundation Trust
National Institute for Health Research, United Kingdom

Recruiting

Endoscopically-delivered Purastat to Treat Bleeding Caused by Radiation Proctopathy (PURASTAT)

Radiation Proctopathy

United Kingdom
Pacira Pharmaceuticals, Inc

Terminated

EXPAREL Administered by Infiltration Into the TAP for Prolonged Postsurgical Analgesia in Lower Abdominal Surgeries (TRANSCEND)

Pain

United States
Meir Medical Center
Meir Hospital, Kfar Saba, Israel

Unknown

The Relationship Between Intraocular Pressure and Macular Edema in Patients With Diabetic Macular Edema

Complications of Diabetes Mellitus

Israel
OPKO Health, Inc.

Terminated

Effects and Safety of OPK-88004 Doses in Men With Signs and Symptoms of Benign Prostatic Hyperplasia (BPH)

Benign Prostatic Hyperplasia

United States
ANRS, Emerging Infectious Diseases
INSERM SC10-US19

Recruiting

Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load (SYNACTHIV)

HIV-1-infection, Subtype b

Belgium, France
Lahey Clinic

Completed

Pilot Study: A Randomized Trial Of Anesthetic Agents For Intravitreal Injection

Macular Degeneration

United States
Allergan

Terminated

Study of Brimonidine and Timolol Ophthalmic Solution With Latanoprost Compared With Latanoprost in Glaucoma Patients

Glaucoma, Angle-Closure

Thailand
Sanofi
Kowa Company, Ltd.

Completed

TOFO Insulin Combination Trial

Type 2 Diabetes Mellitus

Japan
Alcon Research

Completed

Circadian Ocular Perfusion Pressure and Ocular Blood Flow

Glaucoma

United States
Allergan

Completed

Comparing Effects of Two Fixed Combinations Ophthalmic Solutions on Ocular Blood Flow

Glaucoma

United States
Glaukos Corporation

Terminated

Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Astigmatism

Hyperopia | Hyperopic Astigmatism

United States
University of the Incarnate Word
Guardion Health Sciences, Inc.

Withdrawn

Augmented Macular Pigment-containing Nutraceutical and Central Visual Function

Glaucoma | Glaucoma, Open-Angle | Glaucoma Eye

United States
John Mascarenhas
Roche Pharma AG; The Leukemia and Lymphoma Society

Completed

Open Label Study of Single Agent Oral RG7388 in Patients With Polycythemia Vera and Essential Thrombocythemia

Polycythemia Vera | Essential Thrombocythemia

United States
Dana-Farber Cancer Institute
The Leukemia and Lymphoma Society

Active, not recruiting

CIML NK Cells With Venetoclax for AML

Acute Myeloid Leukemia | Leukemia | Leukemia, Myeloid | Acute Myeloid Leukemia Recurrent

United States
M.D. Anderson Cancer Center
Schering-Plough

Terminated

PEG-Intron For Chronic Myelogenous Leukemia Patients Unresponsive To Or Intolerant Of Roferon Or Intron

Leukemia, Myeloid, Philadelphia-Positive

United States
Allergan

Completed

Safety and Efficacy of Combigan® Ophthalmic Solution in Korea

Ocular Hypertension | Glaucoma, Open-Angle

Korea, Republic of
Allergan

Withdrawn

Safety and Efficacy of Triple Combination Therapy With Dorzolamide Hydrochloride / Brimonidine Tartrate / Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma
Innovative Medical

Completed

Brimonidine Purite 0.15% Versus Dorzolamide 2% Used as Adjunctive Therapy to Latanoprost

Glaucoma

United States
Galderma R&D

Completed

Systemic Bioavailability Study Of Col-118 Administered Topically as a 0.18 % Facial Gel And Brimonidine Ophthalmic Solution 0.2%

Erythematous Rosacea

United States
Allergan

Completed

An Evaluation of the Fixed Combination Brimonidine Tartrate 0.2%/ Timolol Maleate 0.5% to Latanoprost 0.005% in Glaucoma or Ocular Hypertension Subjects

Ocular Hypertension | Glaucoma

United States
Allergan

Completed

Study to Evaluate Safety of Brimonidine/Timolol Fixed Combination in Glaucoma or Ocular Hypertension Patients

Ocular Hypertension | Glaucoma

United States
Nicole Fram M.D.

Completed

Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Corneal Transplant Surgery

Intraocular Pressure | Anterior Chamber Inflammation | Ocular Pain | Corneal Edema | Corneal Defect | Penetrating KeratoPlasty | Corneal Transplant

United States
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Boceprevir/Peginterferon Alfa-2a/Ribavirin in Interleukin-28B CC Allele-Positive Chronic Hepatitis C Virus (HCV) Genotype 1 Participants (P07755)

Hepatitis C, Chronic
Leiden University Medical Center
University Medical Center Groningen

Completed

Feasibility of the Combination of Chemotherapy (Carbo/Caelyx or Carbo/Doxorubicin) With Tocilizumab (mAb IL-6R) and Peg-Intron in Patients With Recurrent Ovarian Cancer (PITCH)

Recurrent Ovarian Cancer

Netherlands
Vertex Pharmaceuticals Incorporated
Tibotec Pharmaceutical Limited

Completed

A Phase 3 Study of Telaprevir in Combination With Pegasys® and Copegus® in Treatment-Naive Subjects With Genotype 1 Hepatitis C Virus (HCV)

Hepatitis C

Australia, Canada, France, Italy, Poland, United Kingdom, Germany, United States, Spain, Israel, Argentina, Puerto Rico, Austria

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