Search clinical trials for: ACT-129968

Total 3091 results

Eli Lilly and Company
Locemia Solutions ULC

Completed

Safety and Efficacy of a Novel Glucagon Formulation in Type 1 Diabetic Patients Following Insulin-induced Hypoglycemia (AMG102)

Hypoglycemia

Canada
Astellas Pharma Inc

Completed

A Study to Evaluate the Safety and Efficacy of ASP015K in Moderate to Severe Rheumatoid Arthritis Subjects Who Have Had an Inadequate Response to Methotrexate

Arthritis, Rheumatoid

United States, Poland, Colombia, Belgium, Czechia, Bulgaria, Hungary, Mexico
Qingfeng Pharmaceutical Group

Unknown

Adjunctive Therapy of Andrographolid Sulfonatein Community Acquired Pneumonia

Community Acquired Pneumonia

China
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety of Two Treatment Algorithms in Adults With Moderate to Severe Crohn's Disease (CALM)

Crohn's Disease
London School of Hygiene and Tropical Medicine
DBL -Institute for Health Research and Development

Completed

Relationships Between the Use of Antimalarial Drugs in Pregnancy and Plasmodium Falciparum Resistance

Birth Weight | Malaria in Pregnancy | Anaemia

Burkina Faso
AbbVie (prior sponsor, Abbott)

Completed

Comparison of Efficacy and Safety of Paricalcitol Injection With Maxacalcitol Injection in Adult Japanese Chronic Kidney Disease Subjects Receiving Hemodialysis With Secondary Hyperparathyroidism

Hemodialysis | Secondary Hyperparathyroidism

Japan
Abbott

Completed

Pediatric Switch Study for Children and Adolescent Patients With Epilepsy

Pediatric Epilepsy

United States
Canadian Cancer Trials Group
Bristol-Myers Squibb; Pfizer; Hoffmann-La Roche; AstraZeneca; Seagen Inc.

Recruiting

Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR) (CAPTUR)

Lymphoma, Non-Hodgkin | Multiple Myeloma | Advanced Solid Tumors

Canada
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb; Iovance Biotherapeutics, Inc.

Active, not recruiting

Ipilimumab With Lymphodepletion Plus Adoptive Cell Transfer and High Dose IL-2 in Melanoma Mets Pts

Metastatic Melanoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk Rhabdomyosarcoma

Adult Rhabdomyosarcoma | Embryonal Childhood Rhabdomyosarcoma | Embryonal-botryoid Childhood Rhabdomyosarcoma | Previously Untreated Childhood Rhabdomyosarcoma

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
Arthrex, Inc.

Not yet recruiting

ACP Max™ PRP System for Knee Osteoarthritis: A Feasibility Trial

Knee Osteoarthritis

United States
Assiut University

Completed

ACB Versus IA Analgesia in Knee Arthroscopy

Postoperative Pain

Egypt
AbbVie
Genentech, Inc.

Terminated

Study of ABT-199 (GDC-0199) in Combination With Azacitidine or Decitabine (Chemo Combo) in Subjects With Acute Myelogenous Leukemia (AML)

Acute Myelogenous Leukemia | Myelogenous Leukemia | Treatment Naive AML

United States, Australia, France, Germany
Janssen Research & Development, LLC

Completed

A Study of Abiraterone Acetate Plus Low-Dose Prednisone Plus Androgen Deprivation Therapy (ADT) Versus ADT Alone in Newly Diagnosed Participants With High-Risk, Metastatic Hormone-Naive Prostate Cancer (mHNPC)

Prostate Neoplasms

Canada, France, Poland, Ukraine, United Kingdom, China, Belgium, Spain, Argentina, Colombia, Israel, Mexico, Portugal, Bulgaria, Germany, Malaysia, Romania, South Africa, Turkey, Korea, Republic of, Japan, Australia, Netherlands, Sweden, New Zealand and more
Alexion Pharmaceuticals
Celerion

Completed

A Study of the Cardiac Effects of ALXN2050 in Healthy Adults

Healthy

United States
Shanghai Public Health Clinical Center

Completed

The Drug Interaction Between Albuvirtide (ABT) and Rifampin（RIF） in Healthy Adult Subjects

Drug Interaction

China
Janssen Research & Development, LLC

Completed

Study of Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC), Chemo-Naive, Who Received a Prior Diethylstilbestrol Therapy

Prostatic Neoplasms

Brazil
Charles University, Czech Republic

Completed

Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery. (KOLORIT)

Epidural Analgesia | Morphine | Analgesia, Patient-Controlled | Anesthesia; Spinal | Surgery, Colorectal | Intravenous Drug Delivery Systems

Czechia
Merve Erkmen Almaz

Completed

Effectiveness Fluoride Varnishes in Children With Early Childhood Caries

Early Childhood Caries
Hopital Foch

Terminated

Effect of Epidural Analgesia on the Parameter ANI During Childbirth (APD-ANI)

Labor Pain

France
China Academy of Chinese Medical Sciences
Guang'anmen Hospital of China Academy of Chinese Medical Sciences

Completed

Causal Inference Research of Resistant Hypertension Treatment With Chinese Approach in a Cohort Study

Hypertension, Resistant to Conventional Therapy | Primary Hypertension

China
AbbVie (prior sponsor, Abbott)

Completed

Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)

Chronic Low Back Pain

United States
AbbVie (prior sponsor, Abbott)
Genentech, Inc.

Completed

Phase 2 Study of ABT-869 in Combination With mFOLFOX6 Versus Bevacizumab in Combination With mFOLFOX6 to Treat Advanced Colorectal Cancer

Advanced Colorectal Cancer | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

United States, Australia, Belgium, Brazil, Canada, Czech Republic, Greece, Korea, Republic of, New Zealand, Poland, Portugal, Romania, Russian Federation, Spain
Abbott

Completed

A Year 2, Safety Extension Study of the Combination of ABT-335 and Statin Therapy for Subjects With Mixed Dyslipidemia

Mixed Dyslipidemia

United States
Yonsei University

Unknown

The Beneficial Role of Percutaneous Coronary Intervention Over Optimal Medical Therapy in Elderly Patients With Coronary Artery Disease (BRAVE)

Coronary Artery Disease

Korea, Republic of
Abbott

Completed

A Study of Pain Relief in Osteoarthritis

Osteoarthritis

United States
Abbott

Terminated

A Bioavailability Study of Rifabutin and Lopinavir/Ritonavir in Healthy Adult Subjects

HIV | Tuberculosis

United States
Abbott

Completed

Russian Study of the Efficacy and Safety of Tarka in Patients With Hypertension

Hypertension

United States
Palatin Technologies, Inc

Recruiting

A Phase IIb, Multicenter, Open-Label, Prospective Study of Bremelanotide in Diabetic Kidney Disease (BREAKOUT)

Kidney Disease

United States
University of Sao Paulo General Hospital
InCor Heart Institute

Recruiting

Angiotensin Receptor-Neprilysin Inhibition in Chagas Cardiomyopathy With Reduced Ejection Fraction: ANSWER-HF. (ANSWER-HF)

Chagas Cardiomyopathy

Brazil
National Cancer Institute (NCI)

Active, not recruiting

Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy

Prostate Cancer | Neoplasms of Prostate | Cancer Of Prostate | Prostate Neoplasms | Prostatic Cancer

United States
Nantes University Hospital
Institut National de la Santé Et de la Recherche Médicale, France; Gilead Sciences

Completed

ImmunoTEP for Patients With Medullary Thyroid Carcinoma. (iTEP-CMT)

Medullary Thyroid Carcinoma

France
Takeda

Completed

Safety and Efficacy Study of mFOLFOX6 + Panitumumab Combination Therapy and 5-FU/LV + Panitumumab Combination Therapy in Participants With Chemotherapy-naïve Unresectable Advanced Recurrent Colorectal Carcinoma (SAPPHIRE)

Colorectal Carcinoma

Japan
Nantes University Hospital
Institut National de la Santé Et de la Recherche Médicale, France; Gilead Sciences

Completed

ImmunoTEP au 68-Ga- IMP-288 for Patients With a Recurrence of HER2 Negative Breast Carcinoma Expressing CEA (iTEPsein)

HER2 Negative Breast Carcinoma Expressing CEA

France
Xiaoli Fan

Withdrawn

Paeoniflorin Combination of Hepatoprotective Drugs Versus Hepatoprotective Drugs Only for Auto-immune Hepatitis

Hepatitis, Autoimmune

China
Dana-Farber Cancer Institute
Beth Israel Deaconess Medical Center; Genentech, Inc.; Brigham and Women's Hospital

Completed

Docetaxel, Bevacizumab and Androgen Deprivation Therapy After Definitive Local Therapy for Prostate Cancer

Prostate Cancer

United States
Janssen Scientific Affairs, LLC

Completed

Study to Evaluate the Relative Bioavailability of Fixed-dose Combination Tablet Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) as a Whole Tablet, as a Split Tablet, and as Crushed Tablet in Healthy Adult Participants

Healthy

United States
Yonsei University

Completed

The Effect of Antihypertensive Agents Concerning With Hemodynamics and Reduction of Anaesthetics in Orthognathic Surgery

Orthognathic Surgery

Korea, Republic of
Abbott

Completed

Long Term Safety and Tolerability Study in Approximately 350 Subjects With Moderate to Severe Chronic, Non-malignant Pain

Moderate to Severe Chronic, Non-malignant Pain

United States
Northwestern University
National Cancer Institute (NCI)

Recruiting

FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial

Metastatic Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | Castration-Sensitive Prostate Carcinoma

United States
Hospital Arnau de Vilanova
Pfizer

Unknown

Early Detection of Atherosclerosis: a Randomized Trial in the Primary Prevention of Cardiovascular Diseases. (PRIMARIA)

Cardiovascular Diseases | Atherosclerosis

Spain
Charite University, Berlin, Germany
Stiftung Institut fuer Herzinfarktforschung; Deutsches Zentrum für Herz-Kreislauf-Forschung... and other collaborators

Recruiting

Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy (CLOSURE-AF)

Atrial Fibrillation

Germany
Columbia University

Recruiting

Bile Acids in Acute Insulin Resistance

Cancer | Insulin Resistance | MTOR Gene Mutation | PI3K Gene Mutation | AKT Gene Mutation

United States
Massachusetts General Hospital
Multiple Myeloma Research Consortium

Active, not recruiting

Sotatercept (ACE-011) With Lenalidomide or Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
Spanish Oncology Genito-Urinary Group
Bristol-Myers Squibb; Syntax for Science, S.L

Active, not recruiting

A Trial of Immunotherapy Strategies in Metastatic Hormone-sensitive Prostate Cancer

Metastatic Hormone-sensitive Prostate Cancer

Spain
Janssen Research & Development, LLC

Completed

A Study of Darunavir in the Presence of Cobicistat When Administered as a Fixed Dose Combination Under Fed Conditions

Healthy

Belgium
Hospitales Universitarios Virgen del Rocío
Instituto de Salud Carlos III

Completed

Tripe Versus Dual Antiretroviral Therapy in HIV-infected Patients With Virological Suppression (Tridual) (Tridual)

HIV Infections

Spain
ImmunityBio, Inc.

Withdrawn

QUILT-3.091 NANT Chordoma Vaccine vs Radiation in Subjects With Unresectable Chordoma.

Chordoma | Unresectable Malignant Neoplasm

United States
Dana-Farber Cancer Institute
Celgene Corporation

Terminated

A Phase 1b Study of Paclitaxel And Ricolinostat For The Treatment Of Gynecological Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma

United States
AbbVie
Genentech, Inc.; Celgene Corporation

Withdrawn

A Study of Venetoclax Plus Lenalidomide and Dexamethasone for the Treatment of Newly Diagnosed t(11;14)-Positive Multiple Myeloma in Subjects Who Are Ineligible for High-Dose Therapy

Multiple Myeloma

United States, Australia, Canada, Spain

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