Search clinical trials for: ACT-541468 10 mg

Total 1439 results

Grifols Therapeutics LLC

Completed

Comparison of Pharmacokinetic, Safety, Tolerability of Alpha-1 MP and Prolastin In Alpha1-antitrypsin Deficient Adults (ChAMP)

Alpha 1-Antitrypsin Deficiency

United States
University Hospital, Basel, Switzerland

Recruiting

Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy Subjects (LBL)

Healthy

Switzerland
Korea University Anam Hospital
Hanlim Pharm. Co., Ltd.

Completed

PK Comparisons of Bepotastine Besilate 10 mg and Bepotastine Salicylate 9.64 mg

Allergic Rhinitis | Pruritus | Urticaria

Korea, Republic of
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Loratadine / Pseudoephedrine Sulfate 10/ 240 mg Extended-Release Tablets Under Fed Conditions

Healthy

Canada
Nordsjaellands Hospital

Recruiting

Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures

Colles' Fracture | Fracture Dislocation | Distal Radius Fractures | Lidocaine | Ropivacaine | Closed Reduction of Fracture and Application of Plaster Cast

Denmark
Spero Therapeutics

Completed

Study to Examine the Effect of Antacid and Omeprazole on the Single-Dose Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects

Healthy Volunteers

United States
Vanderbilt University Medical Center

Withdrawn

Mechanism(s) Underlying Cardiovascular Effects of ARB/NEP Inhibition - Aim 2

Heart Failure NYHA Class II | Heart Failure NYHA Class III | Heart Failure NYHA Class I

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)

Metastatic Hormone-Sensitive Prostate Cancer

Taiwan, Poland, United States, Australia, Austria, Brazil, Canada, Chile, China, Colombia, Denmark, Finland, France, Germany, Ireland, Israel, Italy, Japan, Korea, Republic of, Mexico, Netherlands, New Zealand, Peru, Russian Federation, Spai... and more
Almirall, S.A.

Recruiting

A Study of Tirbanibulin Ointment and Diclofenac Sodium Gel for the Treatment of Adult Participants With Actinic Keratosis on the Face or Scalp (AKtive)

Keratosis, Actinic

Poland, Spain, United Kingdom, France, Germany, Italy
Masonic Cancer Center, University of Minnesota

Recruiting

Ruxolitinib, Human Chorionic Gonadotropin (uhCG/EGF), and Dose De-escalated Corticosteroids

Acute-graft-versus-host Disease

United States
Xiaojun Chen

Completed

MPA Versus Dydrogesterone for Management of Endometrial Hyperplasia Without Atypia

Endometrial Hyperplasia Without Atypia

China
Kocaeli University

Completed

Comparison of Erector Spinae Plane Block and Intravenous Analgesic in Nefrectomy

Regional Anesthesia Morbidity | Nephrectomy

Turkey
McNeil AB

Completed

To Test Bioequivalence Between Two Tablet Formulations in the Treatment of Allergy

Allergy

Canada
Acerta Pharma BV

Completed

A Study to Evaluate the Effect of ACP-196 on the Heart Rate-corrected QT Interval in Healthy Adult Participants

Healthy Volunteers

United States
Haukeland University Hospital
Haraldsplass Deaconess Hospital

Recruiting

N-DOSE AD: A Dose Optimization Trial of Nicotinamide Riboside in Alzheimer's Disease

Dementia | Alzheimer Disease

Norway
Walter Reed Army Institute of Research (WRAIR)

Enrolling by invitation

A Comparison of the Physiological and Behavioral Effects of Suvorexant and Zolpidem in Healthy Volunteers: A Randomized, Double-blind, Placebo Controlled Study

Performance Enhancing Product Use

United States
University of Sao Paulo General Hospital

Completed

Action of Intra-auricular Topical Lidocaine on Tinnitus

Tinnitus, Subjective

Brazil
Cristália Produtos Químicos Farmacêuticos Ltda.

Terminated

Esmolol for the Treatment of Hypertension After Intracerebral Hemorrhage Study (ETHICHS) (ETHICHS)

Hemorrhagic Stroke

Brazil
Marathon Pharmaceuticals, LLC

Withdrawn

A Open Label Extension Study for Subjects That Complete Study MP-101-CL-001

Short Bowel Syndrome | Short Gut Syndrome | SBS | Short Gut

United States
Grifols Therapeutics LLC

Completed

Deposition of Inhaled Prolastin in Cystic Fibrosis Patients (CF2)

Cystic Fibrosis
Daewoong Pharmaceutical Co. LTD.

Completed

A Clinical Trial to Evaluate the Efficacy and Safety of Olmesartan/Amlodipine/Rosuvastatin Combination Treatment in Patients With Concomitant Hypertension and Hyperlipidemia

Hypertension | Hyperlipidemias

Korea, Republic of
National Cancer Institute (NCI)

Completed

Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): DNA Microarray Gene Expression Analysis

Chronic Lymphocytic Leukemia

United States
Rajshekhar Chakraborty, MD
Genentech, Inc.

Recruiting

Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis

AL Amyloidosis

United States
Takeda

Completed

Treatment of Hot Flushes Caused by Leuprorelin 11.25 mg in Prostate Adenocarcinoma

Adenocarcinoma, Prostate

France
Ataturk University

Unknown

Ultrasound-Guided Erector Spinae Plan Block in Patients Undergoing ESWL

Pain | Urinary System Stones

Turkey
New Discovery LLC

Recruiting

Tenofovir Disoproxil Fumarate in Combination of Hepatitis B Vaccine for Preventing Hepatitis B Vertical Transmission

Viremia | Hepatitis B Infection | Chronic Infection | Birth Defect | Congenital Malformation

China
Nourhan M.Aly
Alexandria University

Completed

Evaluation of Lycopene in the Treatment of Erosive Oral Lichen Planus

Erosive Lichen Planus

Egypt
Universidad Autonoma de Baja California

Completed

The Outcome of Preoperative Administration of Single-dose Ketorolac, Non-steroidal Anti-inflammatory Drug and Placebo (PreOp)

Pulpitis - Irreversible

Mexico
University Hospital, Limoges

Completed

Reduction in the Risk of Rejection by Mycophenolate Mofetil Dose Adjustment in Liver Transplant Patients With Side Effects Caused by the Calcineurine Inhibitors (MONOCEPT)

Liver Transplantation

France
Natalia Valadares de Moraes
University of Sao Paulo

Completed

Transporters for Organic Cations and Glycemic Control in Patients With Neuropathic Pain.

Type 2 Diabetes Mellitus | Neuropathic Pain | Diabetic Neuropathy, Painful
Alexza Pharmaceuticals, Inc.

Completed

Staccato Prochlorperazine Thorough QT/QTc

Cardiotoxicity

United States
Universitat Internacional de Catalunya
Universidad de los Andes, Chile

Not yet recruiting

Pharmacological Treatment on the Recovery of Neurosensory Disturbance After Bilateral Sagittal Split Osteotomy

Orthognathic Surgery | Prognathism | Neurosensory Disorder | Retrognathism
Hospital for Special Surgery, New York

Completed

Liposomal Bupivacaine vs Dexamethasone ISB

Shoulder Pain

United States
The University of Texas Health Science Center,...
Emory University

Completed

Effect of D-amphetamine on Reward Functioning

Anhedonia

United States
Aswan University Hospital

Completed

Daily Oral L-arginine Plus Tadalafil in Diabetic Patients With Erectile Dysfunction

Erectile Dysfunction

Egypt
Ain Shams University

Completed

Abdominoplasty Under Spinal Anesthesia

Spinal Anesthesia Suitability for Abdominoplasty

Egypt
James J. Peters Veterans Affairs Medical Center

Completed

Body Temperature in Persons With Tetraplegia When Exposed to Cold

Hypothermia | Mild Cognitive Impairment | Tetraplegia

United States
Boehringer Ingelheim

Completed

The Effect of Multiple Oral Doses of BI 1356 BS on Pharmacokinetics, Safety and Tolerability of Multiple Oral Doses of Simvastatin and on the Pharmacokinetics of Its Metabolite Simvastatin Acid in Healthy Male Volunteers

Healthy
Jiangsu Alphamab Biopharmaceuticals Co., Ltd

Completed

Efficacy and Safety Study of KN019 in Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate

Rheumatoid Arthritis

China
Amsterdam UMC, location VUmc

Withdrawn

REGROUP: Renohemodynamic Effects empaGliflozin in vaRiOUs Populations (REGROUP)

Diabetes Mellitus, Type 2 | Chronic Kidney Diseases
Erimos Pharmaceuticals

Terminated

A Phase 1 Continuous Intravenous Infusion Study of Terameprocol (EM-1421) in Subjects With Refractory Solid Tumors

Lymphoma | Refractory Solid Tumors

United States
Ferring Pharmaceuticals

Completed

Safety/Efficacy Study Comparing the Misoprostol Vaginal Insert to Cervidil for Cervical Ripening and Induction of Labor

Labor, Induced | Cervical Ripening

United States, Canada
Birte Glenthoj
Pfizer; Rigshospitalet, Denmark; Glostrup University Hospital, Copenhagen

Terminated

The CAMPUS Project: Cholinergic Augmentation of Cognitive Deficits in Schizophrenia

Schizophrenia

Denmark
Grupo Espanol de Investigacion en Sarcomas

Recruiting

Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas (ImmunoSarc)

Soft Tissue Sarcoma | Bone Sarcoma

Spain, United Kingdom, Italy
Idorsia Pharmaceuticals Ltd.

Completed

To Study the Effect of Cenerimod on the Electrical Activity of the Heart, in Men and Women. To Study the Effect of Cenerimod on the Use of Oral Contraceptives in Women. To Study the Effect That Charcoal Has on the Elimination of Cenerimod From the Body, in Women and Men.

Healthy Subjects

France
Jules Desmeules

Completed

Impact of Genetic Polymorphism on Drug-Drug Interactions Involving CYP2D6

Healthy
Otsuka Pharmaceutical Development & Commercialization...

Completed

Aripiprazole and Effexor XR Drug Interaction Study

Healthy

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Aripiprazole and Lexapro Drug Interaction Study

Healthy

United States
Affiliated Hospital of Jiaxing University

Recruiting

Comparison of Bupivacaine Liposomal vs Bupivacaine Combined With Dexamethasone for Postoperative Pain in VATS

Thoracic Surgery

China
University of Alabama at Birmingham
M.D. Anderson Cancer Center; National Cancer Institute (NCI); University of Colorado... and other collaborators

Active, not recruiting

Low-Dose Tamoxifen Citrate in Reducing Breast Cancer Risk in Radiation-Induced Cancer Survivors (LDTam)

Breast Cancer

United States, Canada

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