Search clinical trials for: ATI-5923

Total 88079 results

Chiesi Farmaceutici S.p.A.

Completed

Efficacy of Fixed Combination of Beclomethasone Dipropionate (BDP) + Formoterol Fumarate (FF) + Glycopyrronium Bromide (GB) (CHF 5993)Administered Via Dry Powder Inhaler (DPI) in Chronic Obstructive Pulmonary Disease (COPD) (TRI-D)

Chronic Obstructive Pulmonary Disease

Bulgaria
Hutchison Medipharma Limited

Active, not recruiting

HMPL-523 (Sovleplenib) in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia (wAIHA)

Warm Antibody Autoimmune Hemolytic Anemia

China
Avanir Pharmaceuticals

Completed

Safety Study of AVP-923 in the Treatment of IEED (Involuntary Emotional Expression Disorder) Also Known as Pseudobulbar Affect (Episodes of Uncontrolled Crying and/or Laughter)

Stroke | Parkinson's Disease | Traumatic Brain Injury | Alzheimer's Disease

United States
Actelion

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of Lucerastat (CDP923) After Multiple Dosing in Healthy Subjects

Healthy Subjects

United Kingdom
Hutchison Medipharma Limited

Completed

A Clinical Study to Evaluate the Pharmacokinetics and Bioequivalence of HMPL-523 Tablets Produced by Two Different Manufacturers

Healthy Subject

China
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI)

Unknown

ERA-923 in Treating Postmenopausal Women With Metastatic Breast Cancer

Breast Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Histiocytic and Dendritic Cell Neoplasm | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Solid Neoplasm | Recurrent... and other conditions

United States, Puerto Rico
Chiesi Farmaceutici S.p.A.

Completed

TRIple in asthMA With uncontRolled pAtient on Medium streNgth of ICS + LABA (TRIMARAN)

Asthma

Germany
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Teropavimab and Zinlirvimab in Combination With Lenacapavir (GS-6207) in Virologically Suppressed Adults With HIV-1 Infection

HIV-1 Infection

United States
National Institute of Allergy and Infectious Diseases...
Gilead Sciences; University of Oxford

Recruiting

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

HIV-1-infection

United States, Brazil
Avanir Pharmaceuticals

Completed

A Phase-1 Study to Assess the Pharmacokinetics, Safety and Tolerability of AVP-786 in Healthy Volunteers

Healthy

Australia
Gilead Sciences

Active, not recruiting

A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection

HIV Infections

United States, Australia, Puerto Rico, Canada
BioMed Valley Discoveries, Inc

Recruiting

Trial of Ulixertinib in Combination With Hydroxychloroquine in Patients With Advanced Gastrointestinal (GI) Malignancies

Gastrointestinal Cancer | Tumor, Solid

United States
Sosei

Terminated

A Multicentre Study to Evaluate the Safety and Efficacy of AD 923 in Comparison to MSIR for the Treatment of CBP in Subjects

Pain | Cancer

United Kingdom
Bayer

Completed

Comparative Cycle Control Europe

Contraception

Germany, Czech Republic, France
University of Utah
BioMed Valley Discoveries, Inc

Completed

Ulixertinib (BVD-523) and Hydroxychloroquine in Patients w Advanced MAPK-Mutated Gastrointestinal Adenocarcinomas (UTAH)

Gastrointestinal Neoplasms

United States
TaiMed Biologics Inc.

Recruiting

TMB-365 and TMB-380 in Suppressed HIV-1 Infected Individuals

HIV-1-infection

United States
Hutchmed

Completed

HMPL-523 Food Effect and Proton Pump Inhibitor Study

Relapsed or Refractory Lymphoma

United States
Avanir Pharmaceuticals

Completed

Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis (PRIME)

Multiple Sclerosis | Central Neuropathic Pain

United States, Spain, Czechia, Poland, Argentina
Hutchison Medipharma Limited

Terminated

Phase I Study of HMPL-523+Azacitidine in Elderly Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia

China
UNC Lineberger Comprehensive Cancer Center
Pfizer; BioMed Valley Discoveries, Inc

Recruiting

Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors

Melanoma | Pancreatic Cancer | Tumor, Solid

United States
M.D. Anderson Cancer Center
Eli Lilly and Company; BioMed Valley Discoveries, Inc

Recruiting

Open-label Phase 1b Study of Ulixertinib and Cetuximab or Ulixertinib in Combination With Cetuximab and Encorafenib in Patients With Unresectable or Metastatic Colorectal Cancer Who Have Previously Received EGFR or BRAF-directed Therapy

Metastatic Colorectal Cancer

United States
Chiesi Farmaceutici S.p.A.
SGS S.A.

Recruiting

Clinical Study to Evaluate the Safety, Tolerability and the Concentration of the BDP (Beclomethasone Dipropionate), Active Metabolite of BDP, FF( Formoterol Fumarate) and GB (Glycopyrronium Bromide), After Inhalation of CHF 5993 at Two Different Doses and QVAR®

Asthma

Belgium
GlaxoSmithKline

Completed

Ability of Four Toothpastes to Remove Plaque

Dental Plaque
Avanir Pharmaceuticals

Completed

Efficacy, Safety and Tolerability Study of AVP-923 (Dextromethorphan/Quinidine) for Treatment of Symptoms of Agitation in Participants With Alzheimer's Disease

Alzheimer's Disease | Agitation

United States
Chiesi Farmaceutici S.p.A.

Completed

Drug-drug Interaction Study of CHF5993 With Cimetidine

COPD

Belgium
Avanir Pharmaceuticals

Completed

Pharmacokinetics (PK) and Tolerability of AVP-786 in Healthy Volunteers

Healthy

Australia
Sandwell & West Birmingham Hospitals NHS Trust
Association of British Clinical Diabetologists

Unknown

Randomisation to Endobarrier Alone Versus With Incretin Analogue in SustainEd Diabesity (REVISE-Diabesity)

Obesity | Type 2 Diabetes | Diabesity

United Kingdom
Amgen

Completed

A Multiple Dose Study to Evaluate Subcutaneous AMG 108 in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis
Chiesi Farmaceutici S.p.A.

Completed

TRIple in Asthma hiGh strenGth vErsus Ics/Laba hs and tiotRopium (TRIGGER) (TRIGGER)

Asthma

Argentina, Belarus, Bulgaria, Czechia, Germany, Hungary, Italy, Lithuania, Poland, Portugal, Romania, Russian Federation, Slovakia, Spain, Turkey, Ukraine, United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate in Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

Italy, Germany, Hungary
Avanir Pharmaceuticals

Completed

Drug Interaction Study Between AVP-923 and Itraconazole and Between AVP-786 and Itraconazole in Healthy Adult Subejcts (DDI)

Healthy

United States
Chiesi Farmaceutici S.p.A.

Completed

Active Controlled Trial of CHF5993 Pressurized Metered-dose Inhaler ( pMDI) vs Symbicort®Turbuhaler® in Patients With Chronic Obstructive Pulmonary Disease ( COPD) (TRIVERSYTI)

COPD (Chronic Obstructive Pulmonary Disease)

China, Korea, Republic of, Taiwan
Pfizer
Biomedical Advanced Research and Development Authority; Innovative Medicines...

Completed

A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria. (REVISIT)

Ventilator Associated Pneumonia | Complicated Intra-abdominal Infection | Hosptial Acquired Pneumonia

Spain, China, Korea, Republic of, Philippines, United States, Romania, Taiwan, Italy, Malaysia, Mexico, India, Israel, Turkey, Greece, Thailand, Czechia, Croatia, Argentina, Russian Federation, Bulgaria, Ukraine
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate the Pharmacokinetics, Safety and Tolerability of CHF 5993 pMDI in Subjects With Renal Impairment. (TRIPLE10)

Chronic Obstructive Pulmonary Disease (COPD)

Poland
ARYx Therapeutics

Completed

Efficacy and Safety Study of an Antiarrhythmic Drug to Treat Atrial Fibrillation in Patients With Pacemakers

Atrial Fibrillation

United States, Canada
Pfizer
Innovative Medicines Initiative (IMI) COMBACTE-CARE

Completed

Determine the PK and Safety and Tolerability of ATM-AVI for the Treatment of cIAIs in Hospitalized Adults (REJUVENATE)

Complicated Intra-Abdominal Infections, cIAIs

Spain, France, Germany
Antios Therapeutics, Inc

Completed

A Phase 1 Double-Blinded Study for Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ATI-2173 in Healthy Subjects and Subjects With Chronic Hepatitis B Virus Infection

Hepatitis B, Chronic

Canada, Moldova, Republic of, Ukraine
Washington University School of Medicine
National Cancer Institute (NCI); BioMed Valley Discoveries, Inc

Terminated

BVD-523 Plus Nab-paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Cancer

Pancreatic Cancer | Pancreas Cancer | Cancer of Pancreas | Cancer of the Pancreas

United States
Avanir Pharmaceuticals

Completed

Study to Assess the Bioavailability, Pharmacokinetics, Safety, and Tolerability of AVP-923 in Healthy Adult Participants

Healthy Adult Male and Female Volunteers

United States
Pfizer

Completed

To Investigate the Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI)

Bacterial Infections | Complicated Infection

United Kingdom
Merck Sharp & Dohme LLC

Completed

A De-Escalating Strategy for Antibiotic Treatment of Pneumonia in The Medical Intensive Care Unit (0787B-092)

Pneumonia | Infection
Chiesi Farmaceutici S.p.A.

Completed

Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate Versus Foster® in COPD

Chronic Obstructive Pulmonary Disease

Hungary
Avanir Pharmaceuticals
Michael J. Fox Foundation for Parkinson's Research

Completed

Safety and Efficacy of AVP-923 in the Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease Patients (LID in PD)

Parkinson's Disease | Dyskinesia

Canada, United States
Hutchmed

Completed

HMPL-523 CYP3A/P-gp Inhibitor and CYP Inducer Study

Relapsed or Refractory Lymphoma

United States
ANRS, Emerging Infectious Diseases

Recruiting

Assessment of HIV Remission Upon cART Interruption in Early Treated Individuals Carrying the MHC B35/53Bw4TTC2 Genotype

HIV Infections

France
American Gene Technologies International Inc.

Enrolling by invitation

An Antiretroviral Treatment Interruption (ATI) Study to Evaluate the Impact of Genetically Modified Autologous Cells (AGT103-T) to Suppress Human Immunodeficiency Virus Replication in the Absence of Antiretroviral Therapy

HIV

United States
Fundación FLS de Lucha Contra el Sida, las Enfermedades...
Aelix Therapeutics

Completed

Study to Assess the Safety and Durability of Viral Control Beyond 24 Weeks of Analytical Treatment Interruption After the Administration of Candidate HIV-1 Vaccines DNA.HTI, MVA.HTI and ChAdOx1.HTI or Placebo in Early Treated HIV-1 Positive Individuals (ATI Extension of AELIX-002 Study)

HIV-1 Infection

Spain
University Medical Center Groningen
Stichting Hemato-Oncologie voor Volwassenen Nederland

Recruiting

Comparison of Point-of-care Produced CAR T-cell With Commercial CAR T-cells in Patients With R/R LBCL (HOVON161)

NHL | DLBCL - Diffuse Large B Cell Lymphoma

Netherlands
Antios Therapeutics, Inc

Terminated

Ethnobridging Study in Healthy Volunteers, Chinese and Japanese Subjects

Chronic Hepatitis b

United States

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