Search clinical trials for: Acid inhibitors

Total 75244 results

Institut de Médecine et d'Epidémiologie Appliquée...

Completed

Pharmacokinetic Study of the Association of Amoxicillin / Clavulanic Acid to Obese Adults (PHACO)

Obesity

France
Milton S. Hershey Medical Center

Terminated

Omega -3 Fatty Acid in Combination With Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia

Chronic Myeloid Leukemia, Chronic Phase

United States
Taipei Veterans General Hospital, Taiwan

Not yet recruiting

Intrathecal Pemetrexed for Leptomeningeal Metastasis in EGFR-Mutant NSCLC

Carcinoma, Non-Small-Cell Lung | Leptomeningeal Metastasis | Epidermal Growth Factor Receptor
Samsung Medical Center

Unknown

A Study Comparing Pemetrexed Plus Cisplatin Versus Pemetrexed Alone in NSCLC Patients Who Have Progressed on First Line EGFR-TKI

Carcinoma, Non-Small-Cell Lung

Korea, Republic of
Eli Lilly and Company

Completed

Chemotherapy for Patients With Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer

Taiwan
Memorial Sloan Kettering Cancer Center
AstraZeneca; Guardant Health, Inc.

Recruiting

Osimertinib Alone or With Chemotherapy for EGFR-Mutant Lung Cancers

Metastatic Non-small Cell Lung Cancer

United States
Akeso

Recruiting

Study of AK119 and AK112 With or Without Chemotherapy for NSCLC Patients

NSCLC

China
Sichuan Kelun Pharmaceutical Research Institute...
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Recruiting

A Phase III Study of SKB264 for EGFR Mutant NSCLC Patients

Non-small Cell Lung Cancer

China
University Hospital, Limoges

Completed

Antibiotherapy During Therapeutic Hypothermia to Prevent Infectious Complications (ANTHARTIC)

Ventilator-associated Pneumonia | Cardiac Arrests With Shockable Rhythm | Mild Therapeutic Hypothermia | Preventive Antibiotics

France
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

A Randomized Comparative Pharmacokinetic Study of Oral Ganciclovir After Treatment With Intravenous Ganciclovir for Cytomegalovirus Gastrointestinal Disease in AIDS Patients

HIV Infections | Colitis

United States
Blueprint Medicines Corporation

Active, not recruiting

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Metastatic Lung Cancer | Antineoplastic Agents | Brain Metastases | Lung Neoplasm Malignant | EGFR... and other conditions

United States, Canada, Korea, Republic of, Japan, Taiwan
Samsung Medical Center

Completed

Pemetrexed Plus Tarceva as Salvage Treatment in EGFR Overexpressed Metastatic Colorectal Cancer Patients Who Were Failed After Standard Chemotherapy

Colo-rectal Cancer

Korea, Republic of
German Heart Center

Unknown

Comparison of Aprotinin and Tranexamic Acid in Routine Cardiac Surgery

Coronary Artery Bypass Graft Surgery | Aortic Valve Replacement | Bleeding and Cardiac Surgery | Allogeneic Blood Transfusion

Germany
Shire

Withdrawn

ARALAST NP Alpha-1 Lung Density Chronic Obstructive Pulmonary Disease-Emphysema (COPD-E) Study

Chronic Obstructive Pulmonary Disease | Alpha1-antitrypsin Deficiency
GlaxoSmithKline

Completed

A Phase I Study Of Pazopanib With Either Erlotinib Or Pemetrexed In Patients With Advanced Solid Tumors

Lung Cancer, Non-Small Cell

United States, Italy
National Cheng-Kung University Hospital

Unknown

Tailored Second Line Treatment by Epidermal Growth Factor Receptor (EGFR) Mutation in Patients With Advanced Lung Adenocarcinoma

Non-Small Cell Lung Cancer

Taiwan
Menzies School of Health Research
University of Malaya; Nanyang Technological University; Griffith University; The... and other collaborators

Active, not recruiting

Hospitalised Pneumonia With Extended Treatment (HOPE) Study (HOPE)

Pneumonia

Australia, Malaysia, New Zealand
Consorci Sanitari de Terrassa
Corporacion Parc Tauli

Completed

Trial Assessing the Efficacy of a Short Course of Intravenous Antibiotic Followed by Oral Antibiotic in Uncomplicated Acute Diverticulitis (DANC-05)

Diverticulitis

Spain
Maggiore Bellaria Hospital, Bologna

Completed

Non Operative Treatment for Acute Appendicitis (NOTA)

Acute Appendicitis | Lower Abdominal Pain | Right Iliac Fossa Pain

Italy
AstraZeneca

Recruiting

A Study of Osimertinib With or Without Chemotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung Cancer (NeoADAURA)

Non-Small Cell Lung Cancer

China, United States, Chile, Vietnam, Thailand, Brazil, Bulgaria, Canada, Germany, India, Japan, Korea, Republic of, Poland, Russian Federation, Singapore, Turkey, Austria, Israel, Spain, Taiwan, Mexico, France, Italy, Peru, Switzerland, United...
Novartis Pharmaceuticals

Terminated

Study Evaluating Efficacy and Safety of Capmatinib in Combination With Osimertinib in Adult Subjects With Non-small Cell Lung Cancers as Second Line Therapy (GEOMETRY-E)

Carcinoma, Non-Small-Cell Lung

Japan, Korea, Republic of, Singapore
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Sintilimab ± IBI305 Plus Chemotherapy (Pemetrexed + Cisplatin) for EGFRm + Locally Advanced or Metastasis Non-Squamous NSCLC Patients After EGFR-TKI Treatment Failure

Non-Squamous Non-Small Cell Lung Cancer

China
CHU de Quebec-Universite Laval

Unknown

The Use of Prophylactic Antibiotics in Endoscopy Sinus Surgery for Chronic Rhinosinusitis With or Without Polyp

Chronic Sinus Infection

Canada
Guangzhou Medical University

Recruiting

Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer

Leptomeningeal Metastasis

China
Ohad Ronen

Completed

Maxillary Sinus Irrigation in the Management of Chronic Rhinosinusitis

Sinusitis

Israel
Phillip Brian Smith

Withdrawn

Pharmacokinetics and Safety of Ticarcillin-clavulanate in Infants

Sepsis

United States
BerGenBio ASA

Recruiting

A Study to Investigate the Safety, Tolerability, and Preliminary Anti-tumor Activity of Bemcentinib in Combination With Pembrolizumab Plus Pemetrexed and Carboplatin in Adult Participants With Untreated Non-squamous Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States
Dr Joanne CHIU

Recruiting

Pembrolizumab, Lenvatinib and Chemotherapy After TKIs in NSCLC

ALK Gene Rearrangement Positive | EGF-R Positive Non-Small Cell Lung Cancer | EGFR Activating Mutation | Nsclc | ROS1 Gene Rearrangement | ROS1 Positive NSCLC - Reactive Oxygen Species 1 Positive Non-Small Cell Lung Cancer

Hong Kong
Hikma Pharmaceuticals LLC

Terminated

Randomized Comparative Study of Erlotinib and Pemetrexed in the Maintenance Treatment of Advanced Lung Cancer Patients.

Carcinoma, Non-Small-Cell Lung

Lebanon, Jordan
Queen Mary University of London
Hoffmann-La Roche; Polaris Group

Withdrawn

Study in Patients With Tumours Requiring Arginine to Assess ADI-PEG 20 With Atezolizumab, Pemetrexed and Carboplatin (iTRAP)

Carcinoma, Non-Small-Cell Lung
TASK Applied Science
GlaxoSmithKline; Research Center Borstel; Eduardo Mondlane University; Barcelona...

Completed

Phase 2 Trial to Evaluate the Early Bactericidal Activity, Safety and Tolerability of Meropenem Plus Amoxycillin/CA and Faropenem Plus Amoxycillin/CA in Adult Patients With Newly Diagnosed Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
Takeda

Active, not recruiting

TAK-788 as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations

Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

United States, Spain, France, Korea, Republic of, Israel, Hong Kong, Australia, Taiwan, United Kingdom, Canada, Turkey, Italy, China, Germany, Russian Federation, Switzerland, Austria, Japan, Denmark, Belgium, Greece, Netherlands, P... and more
Shanghai JMT-Bio Inc.

Not yet recruiting

JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations

Local Advanced or Metastatic NSCLC
IRCCS Burlo Garofolo

Completed

Short Therapy for Febrile UTI in Childhood

Urinary Tract Infections

Italy
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Active, not recruiting

A Clinical Trial of TQB2450 Injection Combined With AL2846 Capsules in Patients With Advanced Solid Tumors

Solid Tumor

China
University of Colorado, Denver

Recruiting

Response of Bony Metastasis to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancers With Actionable Driver Mutations.

Carcinoma, Non-Small-Cell Lung

United States
Janssen Scientific Affairs, LLC
Bayer

Completed

A Study to Assess the Independent Effects of 4-Factor Prothrombin Complex Concentrate and Tranexamic Acid on Bleeding/Pharmacodynamics in Healthy Participants

Healthy

United States
University of Padova
IL Sogno di Stefano; Regione Veneto

Terminated

Oral vs Initial Intravenous Antibiotic Treatment of Urinary Tract Infections in Children: a RCT

Urinary Tract Infections
Southeast University, China

Completed

Efficacy, Safety and Tolerability of Telbivudine in HBeAg Positive Chronic Hepatitis B Pregnant Women With Elevated Alanine Aminotransferase Levels

Chronic Hepatitis B | Pregnancy Complications | High Viral Load | Elevated Alanine Aminotransferase Levels

China
Hanna Jangö
Region Hovedstadens Apotek

Recruiting

Oral Antibiotics After Obstetric Perineal Tear (REPAIR)

Infections | Wound Dehiscence | Obstetric Trauma

Denmark
Teva Pharmaceuticals USA

Completed

Amoxicillin-Clavulanic Acid 400 mg-57 mg Chewable Tablets Under Fasting Conditions

Healthy

Canada
The Netherlands Cancer Institute

Withdrawn

Combination of Platinum Doublets and Hypofractionated Radiotherapy in NSCLC (HYPOLAN)

Non-Small Cell Lung Cancer
Temple University
Medical University of South Carolina; University of Pennsylvania; Research Foundation...

Recruiting

Clavulanic Acid for the Treatment of Cocaine Use Disorder

Cocaine Dependence

United States
Lantern Pharma Inc.

Recruiting

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma (HARMONIC)

Carcinoma, Non-Small-Cell Lung | Adenocarcinoma of Lung

United States
Swiss Tropical & Public Health Institute
Swiss Academy of Medical Sciences (SAMS)

Completed

Benefit of a Single Preoperative Dose of Antibiotics for the Prevention of Surgical Site Infections (SSI2)

Surgical Site Infection

Switzerland
UPECLIN HC FM Botucatu Unesp

Completed

Comparison Between Amoxycillin/Clavulanic Acid and Oxacillin/Ceftriaxone for Community Acquired-pneumonia

Community-Acquired Pneumonia

Brazil
Teva Pharmaceuticals USA

Completed

Amoxicillin-Clavulanic Acid 400 mg-57 mg Chewable Tablets Under Non-Fasting Conditions

Healthy

Canada
Southwest Oncology Group
National Cancer Institute (NCI)

Terminated

S1300: Pemetrexed Disodium With or Without Crizotinib in Treating Patients With Stage IV Non-Small Cell Lung Cancer That Has Progressed After Crizotinib

Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Adenocarcinoma of the Lung | Large Cell Lung Cancer

United States
Latin American Cooperative Oncology Group
Janssen, LP

Recruiting

Amivantamab, Lazertinib, and Pemetrexed for First-line Treatment of Recurrent/Metastatic Non-small Cell Lung Cancers With Epidermal Growth Factor Receptor Mutations (AMIGO-1)

Metastatic Non-small Cell Lung Cancers

Brazil
University Hospital Inselspital, Berne
Schweizerische Unfallversicherung SUVA, Switzerland; Mepha Parma AG, Switzerland and other collaborators

Terminated

Duration of Postoperative Antibiotic Prophylaxis in Facial Fractures

Surgical Wound Infection

Switzerland

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