Search clinical trials for: Adrenergic alpha-Agonists

Total 19049 results

Technische Universität Dresden
Prof. Dr. Veit Roessner and PD Dr. Robert Waltereit jointly lead and conduct...

Unknown

Affective Dysregulation (AD) in Children With ADHD Treated by Guanfacin

Affective Dysregulation
General Hospital of Ningxia Medical University

Not yet recruiting

90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard Treatment in Preeclamptic Patients

Adverse Effect
US Department of Veterans Affairs

Completed

Guanfacine for the Treatment of Post Traumatic Stress Disorder (PTSD)

Post-Traumatic Stress Disorder

United States
University of Alabama at Birmingham

Not yet recruiting

Efficacy of Topical Apraclonidine for the Treatment of Ocular Synkinesis

Synkinesis | Facial Nerve Palsy

United States
General Hospital of Ningxia Medical University

Not yet recruiting

90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard Treatment

Adverse Effect
Imperial College London

Recruiting

Noradrenergic Add-on Therapy With Guanfacine (NorAD)

Alzheimer Disease

United Kingdom
Vanderbilt University Medical Center
Massachusetts General Hospital; National Institute on Aging (NIA)

Active, not recruiting

Maximizing trEatment of Neurological Dysfunction Using INtravenous Guanfacine Study (MENDING)

Delirium | Critical Illness | Cognitive Impairment

United States
Vanderbilt University Medical Center

Completed

Guanfacine for PONV and Pain After Sinus Surgery

Pain, Postoperative | Postoperative Nausea and Vomiting

United States
Yale University
National Institute on Aging (NIA)

Completed

Guanfacine Treatment for Prefrontal Cognitive Dysfunction in Elderly Subjects

Cognitive Aging

United States
Aswan University Hospital

Completed

Intravenous Versus Peribulbar Dexmedetomidine for Strabismus Surgery in Adults

Squint

Egypt
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Guanfacine Clinical Trial for Smoking Cessation

Smoking Cessation

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

PK/PD Comparison of Guanfacine ER and IR

Smoking

United States
Heinrich-Heine University, Duesseldorf

Terminated

The Effect of Topical Brimonidine Tartrate on Hand-foot Syndrome (HFS) in Cancer Patients (BRIMOCAN)

Hand-foot Syndrome

Germany
Allergan

Completed

Safety and Efficacy of Brimonidine in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma
National Institute of Neurological Disorders and...

Terminated

Oral Guanabenz for Multiple Sclerosis

Multiple Sclerosis | Multiple Sclerosis, Relapsing-Remitting

United States
Icahn School of Medicine at Mount Sinai
National Institute of Mental Health (NIMH)

Terminated

Pharmacology of Cognition in Schizotypal Personality Disorder

Personality Disorders | Schizotypal Personality Disorder

United States
National Center for Research Resources (NCRR)
Yale University

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Guanfacine for Tourette Syndrome and Attention Deficit Hyperactivity Disorder

Tourette Syndrome
General Hospital of Ningxia Medical University

Not yet recruiting

90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment in Preeclamptic Patients

Adverse Effect
Radboud University Medical Center

Unknown

Cardiovascular and Autonomic Reactivity in Women With a History of Pre-eclampsia

Preeclampsia

Netherlands
Sarah Network of Rehabilitation Hospitals
University of Brasilia

Unknown

Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion (eMUNODEX)

Spondylolisthesis | Spondylolysis | Spine; Arthrosis | Spondylolysis, Multiple Sites in Spine

Brazil
Imperial College London
Wellcome Trust

Completed

Guanfacine for the Treatment of Spatial Neglect and Impaired Vigilance (GASNIV)

Stroke | Hemispatial Neglect

United Kingdom
New York State Psychiatric Institute

Completed

Open-Label Pilot Study of Guanfacine-Extended Release for the Treatment of Cannabis Dependence (GUAN)

Cannabis Dependence

United States
Stanford University

Recruiting

The BIomarker Guided Study for Depression (BIG)

Major Depressive Disorder

United States
University of Alabama at Birmingham

Completed

The Effect of Guanfacine on Delirium in Critically Ill Patients

Delirium

United States
Yale University
National Institute on Drug Abuse (NIDA); National Institute on Alcohol Abuse... and other collaborators

Completed

Modeling Stress-precipitated Smoking Behavior for Medication Development

Smoking

United States
Actavis Inc.
Watson Laboratories, Inc.

Completed

Randomized, Double-blind, Multiple-site, Placebo-controlled, Parallel-design Study in Patients With Moderate to Severe Facial Erythema Associated With Rosacea

Rosacea

United States
Galderma Brasil Ltda.
Eurotrials Brasil Consultores Cientificos Ltda

Completed

A Multicenter, Open-label Clinical Trial to Evaluate the Efficacy and Safety of Once Daily Mirvaso® Gel in Patients With Chronic Persistent Vascular Facial Erythema. (BR14004)

Chronic Persistent Vascular Facial Erythema

Brazil
Icahn School of Medicine at Mount Sinai

Unknown

Guanfacine to Treat Borderline Personality Disorder

Borderline Personality Disorder

United States
Medical University of Vienna

Withdrawn

Relation Between Intraocular Pressure Lowering Effects of Topical Brimonidine and Alpha 2 Receptor Polymorphism

Intraocular Pressure | Ocular Physiology

Austria
Charite University, Berlin, Germany
German Federal Ministry of Education and Research

Recruiting

Treating Nightmares in Posttraumatic Stress Disorder With Clonidine and Doxazosin

Posttraumatic Stress Disorder

Germany
Rochester Center for Behavioral Medicine
Shire

Completed

Efficacy and Safety Eval of Guanfacine Hydrochloride in Combination With Psychostimulants in Adults (18-65). (ADINT2012)

Adult Attention-Deficit Hyperactivity Disorder

United States
Medical University of Vienna

Completed

Effects of Topical Clonidine vs. Brimonidine on Choroidal Blood Flow and Intraocular Pressure During Isometric Exercise

Ocular Physiology | Regional Blood Flow

Austria
Rachel G. Greenberg, MD, MB, MHS
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Not yet recruiting

Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS) (HYP01)

Hyperactivity in Children With Down Syndrome | Impulsivity in Children With Down Syndrome

United States
NYU Langone Health
Winthrop University Hospital

Withdrawn

Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
Galderma R&D

Completed

Mirvaso in Use Study

Rosacea

United States
Shire

Completed

SPD503 (Guanfacine Hydrochloride) in ADHD Plus Oppositional Symptoms

ADHD

United States
Shire

Completed

Safety, Tolerability and Efficacy of SPD503 in Treating ADHD in Children Aged 6-17

Attention Deficit Disorder With Hyperactivity
Massachusetts Eye and Ear Infirmary

Completed

Effect of Alphagan on Retinal Blood Flow Autoregulation and Motion Detection in Patients With Normal Pressure Glaucoma

Glaucoma

United States
Neurology Group of Bergen County, P.A.
Shire

Completed

Language-based Learning Skills and Attention Deficit Hyperactivity Disorder (ADHD): Impact of Treatment With Sustained-release Guanfacine

Attention-deficit/Hyperactivity Disorder

United States
University of Parma

Completed

Brimonidine vs ALTP in Progressing Human Glaucoma

Glaucoma

Italy
Denver Health and Hospital Authority

Completed

Pupil Dilation for Treatment of IFIS

Intraoperative Floppy Iris Syndrome

United States
Icahn School of Medicine at Mount Sinai
Brain & Behavior Research Foundation

Completed

CRT-Guanfacine for SPD

Schizotypal Personality Disorder | SPD

United States
Nanduri, Padma, M.D., FACS

Unknown

Intraocular Pressure (IOP) Lowering Efficacy of Transdermal Brimonidine Therapy

Glaucoma

United States
Astellas Pharma Inc
Astellas Pharma Singapore Pte. Ltd.

Completed

A Phase 4 Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Male Subjects With Overactive Bladder (OAB) Symptoms, While Taking the Alpha Blocker for Benign Prostatic Hypertrophy (BPH)

Overactive Bladder

Japan, Korea, Republic of
George Papanicolaou Hospital

Unknown

Esmolol Versus Dexmedetomidine During Intracranial Procedures

Intracranial Aneurysm | Intracranial Neoplasms

Greece
Yale University
University of South Florida; New York University; Icahn School of Medicine at... and other collaborators

Completed

Guanfacine in Children With Tic Disorders

Tourette Syndrome | Tourette Disorder

United States
Shire

Completed

Efficacy and Safety of SPD503 in Combination With Psychostimulants

ADHD

United States
Maimonides Medical Center

Recruiting

Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome (PWS-GXR)

Aggression | Behavioral Symptoms | Pathologic Processes | Nervous System Diseases | Obesity | Neurologic Manifestations | Neurobehavioral Manifestations | Congenital Abnormalities | Overnutrition | Nutrition Disorders | Genetic Diseases, Inborn | Intellectual Disability | Self-Injurious Behavior | Abnormalities, Multiple and other conditions

United States
Shire

Completed

Maintenance of Efficacy of Extended-Release Guanfacine HCl in Children and Adolescents With Attention-deficit/Hyperactivity Disorder (ADHD)

Attention-deficit/Hyperactivity Disorder

Spain, Belgium, United States, Netherlands, United Kingdom, Italy, Germany, Canada, France, Sweden
Kathy Miller

Terminated

Study Evaluating the Biologic Activity of Guanabenz in Bone Metastasis

Bone Cancer | Metastasis

United States

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