Search clinical trials for: Aerosolized Infasurf

Total 57 results

ONY

Terminated

Infasurf®(Calfactant) Aerosol for Infants With Bronchiolitis-AERO-04

Bronchiolitis

United States
ONY

Completed

Comparison of Aerosol Delivery of Infasurf to Usual Care in Spontaneously Breathing RDS Patients

Respiratory Distress Syndrome

United States
Roberta Ballard
Mallinckrodt; ONY

Completed

Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric Oxide (TOLSURFPilot)

Bronchopulmonary Dysplasia | Respiratory Distress Syndrome of Prematurity (Surfactant Dysfunction)

United States
Region Skane

Recruiting

Aerosoliserat DNase for Treatment of Respiratory Failure in Severe COVID-19

COVID-19

Sweden
Children's Hospital of Philadelphia
University of Pennsylvania; Women & Children's Hospital of Buffalo

Completed

Pilot Trial of Surfactant Therapy For Preterm Neonates 5-21 Days Old With Respiratory Decompensation

Respiratory Distress Syndrome
Jiangsu Province Centers for Disease Control and...

Active, not recruiting

Heterologous Prime-boost Immunization With an Aerosolised Adenovirus Type-5 Vector-based COVID-19 Vaccine (Ad5-nCoV) After Priming With an Inactivated SARS-CoV-2 Vaccine

COVID-19

China
Kafrelsheikh University
Damietta University

Unknown

Aerosol Combination Therapy of All-trans Retinoic Acid and Isotretinoin as A Novel Treatment for Inducing Neutralizing Antibodies in COVID -19 Infected Patients Better Than Vaccine : An Innovative Treatment (Antibodies)

COVID-19
ONY

No longer available

Aerosolized Infasurf Treatment Protocol: Aerosolized Infasurf for Spontaneously Breathing Patients With Early RDS (AERO-03)

Neonatal Respiratory Distress

United States
Dr. Michael Flavin

Withdrawn

Treating Wheezing in Children With Hypertonic Saline (TWICS) (TWICS)

Wheeze
Children's Hospital of Philadelphia
University of Pennsylvania; Children's Mercy Hospital Kansas City; St. Louis... and other collaborators

Completed

Pilot Trial of Surfactant Booster Prophylaxis For Ventilated Preterm Neonates

Respiratory Distress Syndrome | Bronchopulmonary Dysplasia
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Aerosolized Aldesleukin in Treating Patients With Lung Metastases

Sarcoma | Metastatic Melanoma | Metastatic Renal Cell Cancer | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Stage IV Osteosarcoma AJCC v7 | Metastatic Osteosarcoma | Stage IV Renal Cell Cancer AJCC v7 | Metastatic Malignant Neoplasm in the Lung

United States
Jiangsu Province Centers for Disease Control and...
Hunan Provincial Center for Disease Control and Prevention; Yunnan Center for... and other collaborators

Active, not recruiting

Heterologous Boost Immunization With an Aerosolised Ad5-nCoV After Two-dose Priming With an Inactivated SARS-CoV-2 Vaccine

COVID-19

China
University of Missouri-Columbia

Completed

Comparison of Curosurf and Infasurf in the Treatment of Preterm Infants With Respiratory Distress Syndrome (NEOSURF)

Respiratory Distress Syndrome

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

SARS-CoV-2 Infection Among Healthcare Workers

COVID-19

China
Wright State University

Terminated

Aerosolized Antibiotics in the Treatment of Ventilator Associated Pneumonia (AAINTVAP)

Pneumonia, Ventilator-Associated

United States
ONY
Avania

Not yet recruiting

InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS (Aero-05)

Intubation Complication | Death; Neonatal | Respiratory Distress Syndrome (Neonatal)

United States
National Cancer Institute (NCI)

Recruiting

Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-small Cell Lung Cancer

Advanced Non Small Cell Lung Cancer

United States
University of Pittsburgh
Cystic Fibrosis Foundation

Completed

Self-dispersing Liquids as Aerosol Drug Carriers

Cystic Fibrosis

United States
Heidelberg University

Completed

Iloprost-Study: Comparison of Nitric Oxide to Iloprost (Ventavis) for Treatment of Pulmonary Hypertension in Children After Cardiopulmonary Bypass Surgery

Pulmonary Hypertension

Germany
Pari Pharma GmbH

Terminated

Long-term Safety Follow-up Study in the Prevention of Bronchiolitis Obliterans Syndrome (BOS)

Bronchiolitis Obliterans

Germany
Windtree Therapeutics

Terminated

Feasibility Study of Aerosolized Surfaxin in the Prevention of Respiratory Distress Syndrome (RDS) in Premature Infants

Respiratory Distress Syndrome

United States
Hannover Medical School

Terminated

Combination Therapy of Bosentan and Aerosolized Iloprost in Idiopathic Pulmonary Arterial Hypertension (IPAH)

Hypertension

Germany
Roberta Ballard
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia (TOLSURF)

Bronchopulmonary Dysplasia

United States
Jiangsu Province Centers for Disease Control and...

Not yet recruiting

Effectiveness of a Second COVID-19 Vaccine Booster in Chinese Adults

COVID-19

China
Kafrelsheikh University

Unknown

Efficacy and Safety of Drug Combination Therapy of Isotretinoin and Some Antifungal Drugs as A Potential Aerosol Therapy for COVID-19 : An Innovative Therapeutic Approach COVID-19 (Isotretinoin)

Covid19

Egypt
Bayer
Nektar Therapeutics

Completed

Inhaled Amikacin Solution BAY41-6551 as Adjunctive Therapy in the Treatment of Gram-Negative Pneumonia (INHALE 1)

Pneumonia, Bacterial

Korea, Republic of, Taiwan, United States, Canada, Philippines, Turkey, Thailand, Australia, Mexico, Colombia, Czechia, Brazil
Jiangsu Province Centers for Disease Control and...

Active, not recruiting

Heterologous Boost Immunization With Ad5-nCoV After Three-dose Priming With an Inactivated SARS-CoV-2 Vaccine

COVID-19

China
Seattle Children's Hospital

Completed

Improving Sedation of Children Undergoing Procedures in the Emergency Department

Anxiety
Case Western Reserve University
Cystic Fibrosis Foundation

Withdrawn

Pharmacokinetics of Vancomycin for Inhalation in Cystic Fibrosis

Cystic Fibrosis | Methicillin-resistant Staphylococcus Aureus

United States
Hat Yai Medical Education Center

Terminated

Aerosolized Plus Intravenous vs. Intravenous Colistin for VAP Due to Pandrugs-resistant A. Baumannii in Neonates

Pneumonia, Ventilator-Associated | Colistin Adverse Reaction | Infection Due to Multidrug Resistant Acinetobacter | Infection Resistant to Multiple Drugs

Thailand
M.D. Anderson Cancer Center
Gateway for Cancer Research; James B. and Lois R. Archer Charitable Foundation

Recruiting

Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

Malignant Neoplasms of Female Genital Organs | Malignant Neoplasms of Lip Oral Cavity and Pharynx | Melanoma and Other Malignant Neoplasms of Skin | Malignant Neoplasm of Bone and Articular Cartilage | Malignant Neoplasms of Independent (Primary) Multiple Sites | Malignant Neoplasm of Male... and other conditions

United States
University of Virginia
ONY; LMA North America

Terminated

Randomized Controlled Trial of Surfactant Administration by Laryngeal Mask Airway (LMA)

Respiratory Distress Syndrome, Newborn

United States
Pinnacle Health System

Completed

Clinical Proposal for the Comparison of Intraperitoneal Anesthetic to Injected Local Anesthetic

Pain, Postoperative | Morbid Obesity

United States
Kafrelsheikh University
Ministry of Health, Saudi Arabia; Foshan University Laboratory of Emerging... and other collaborators

Not yet recruiting

Investigating the Potential Role of Aerosolized Retinoic Acid, a Potent Vitamin A Metabolite for Treating COVID-19 Anosmia and Retinoic Acid Insufficiency .A Novel Approach for Regaining Sense of Smell.

Post COVID-19 Anosmia (Loss of Smell)

China, Egypt, Saudi Arabia
Kafrelsheikh University
1-Foshan University Laboratory of Emerging Infectious Disease Institute of... and other collaborators

Not yet recruiting

Assessment the Activity Value of Isotretinoin (13- Cis-Retinoic Acid ) in the Treatment of COVID-19 ( Isotretinoin in Treatment of COVID-19) (Randomized) (Isotretinoin)

COVID19

Egypt
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Terminated

Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF)

Respiratory Insufficiency | Pulmonary Hypertension | Respiratory Distress Syndrome, Newborn | Prematurity

United States
Stony Brook University
Nektar Therapeutics

Completed

Aerosolized Antibiotics and Respiratory Tract Infection in Patients on Mechanical Ventilation

Ventilator Associated Pneumonia | Respiratory Infection | Tracheobronchitis

United States
Beth Israel Deaconess Medical Center
National Institute of Nursing Research (NINR)

Completed

Aerosol Inhalation Treatment for Dyspnea - Patients

Dyspnea

United States
Cardeas Pharma

Completed

Aerosolized Amikacin and Fosfomycin in Mechanically Ventilated Patients With Gram-negative Pneumonia (IASIS)

Pneumonia, Bacterial

Spain, United States, Greece, Hungary, Turkey, Puerto Rico, France
Kafrelsheikh University

Not yet recruiting

Combination of Recombinant Bacterial ACE2 Receptors -Like Enzyme of B38-CAP and Isotretinoin Could be Promising Treatment for COVID-19 Infection- and Its Inflammatory Complications

COVID
Cardeas Pharma

Withdrawn

Aerosolized Amikacin and Fosfomycin in Mechanically Ventilated Patients With Gram-negative and / or Gram-positive Bacterial Colonization

Pneumonia, Bacterial
Kafrelsheikh University

Not yet recruiting

Investigating the Role of 13cis Retinoic Acid in the Treatment of COVID-19 and Enhancement of Its Spike Protein Based Vaccine Efficacy and Safety. (Isotretinoin)

Covid19 Vaccine
Baxalta now part of Shire
Arriva Pharmaceuticals, Inc.

Completed

Study of the Effect of Aerosolized, Recombinant Alpha 1-Antitrypsin on Epithelial Lining Fluid Analytes in Subjects With Alpha 1-Antitrypsin Deficiency

Alpha1-antitrypsin Deficiency

United States
University of Florida
National Institute on Deafness and Other Communication Disorders (NIDCD)

Completed

Cough According to Stimulus Type in PD

Parkinson's Disease

United States
Cynthia McEvoy
University of Florida; University of California, San Francisco; Thrasher Research... and other collaborators

Completed

Steroids and Surfactant in Extremely Low Gestation Age Infants Dose Escalation Trial (SASSIE)

Bronchopulmonary Dysplasia (BPD)

United States
Baxalta now part of Shire
Arriva Pharmaceuticals, Inc.

Completed

Safety Study of an Aerosolized, Recombinant Alpha 1-Antitrypsin in Subjects With Alpha 1-Antitrypsin Deficiency

Alpha1-antitrypsin Deficiency

United States
East Carolina University

Unknown

Pilot Study of Topical Steroid for Prevention of Chronic Lung Disease in Extremely Premature Infants.

Bronchopulmonary Dysplasia

United States
Kamada, Ltd.

Completed

Phase II Study of the Safety and Efficacy of Inhaled Alpha-1 Antitrypsin (AAT ) in Cystic Fibrosis Patients

Cystic Fibrosis

Israel
Kafrelsheikh University

Unknown

Clinical Role of Testosterone and Dihydrotestosterone and Which of Them Should be Inhibited in COVID-19 Patients - A Double-edged Sword?

Covid19
Pulmoquine Therapeutics, Inc
Rockefeller University

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Orally Inhaled Aerosolized Hydroxychloroquine Sulfate in Healthy Adult Volunteers

Severe Acute Respiratory Syndrome Coronavirus 2

United States

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