Search clinical trials for: Afegostat tartrate

Total 627 results

Novo Nordisk A/S

Terminated

Effect of Insulin Detemir on Use of Energy in Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

United Kingdom
Purdue Pharma LP

Completed

Long-term Safety of Once-daily Hydrocodone Bitartrate (HYD) Tablets For Moderate to Severe Chronic Nonmalignant and Nonneuropathic Pain. Includes a 24-week Extension Period.

Chronic Nonmalignant and Nonneuropathic Pain

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg and Lopressor HCT® Tablets 100/50 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg to Lopressor HCT® Tablets 100/50 mg

Healthy

United States
Aristotle University Of Thessaloniki
Alcon Research

Completed

24-Hour Intraocular Pressure With Brinzolamide/Timolol Versus Brimonidine/Timolol

Glaucoma
Celgene

Terminated

A Phase I/II Study of ABI-007 (Abraxane®, Nab®-Paclitaxel)and Vinorelbine in Patients With Stage IV (Metastatic) Breast Cancer

Stage IV (Metastatic) Breast Cancer

United States
Medical University of Vienna

Completed

Effect of Xalacom® (Latanoprost/Timolol) and Combigan® (Brimonidine/Timolol) Fixed Combination on Intraocular Pressure and Ocular Blood Flow in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular Physiology | Retina

Austria
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time

Chronic Pain

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI); Susan G. Komen Breast Cancer Foundation

Completed

Vaccine Therapy, Trastuzumab, and Vinorelbine in Treating Patients With Locally Recurrent or Metastatic Breast Cancer

Breast Cancer

United States
Samuel Lunenfeld Research Institute, Mount Sinai...

Completed

Norepinephrine To Prevent Hypotension After Spinal Anesthesia For Cesarean Delivery: A Dose Finding Study

Hypotension

Canada
Cephalon

Completed

A Study to Assess the Abuse Potential of Hydrocodone Extended-Release Tablet in Recreational Opioid Users

Drug Abuse

United States, Canada
University of Washington
National Cancer Institute (NCI)

Terminated

Hormone Therapy and Combination Chemotherapy Before and After Surgery in Treating Patients With Stage I-IIIA Breast Cancer

Stage I Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Estrogen Receptor-positive Breast Cancer | Progesterone Receptor-positive Breast Cancer | HER2-negative Breast Cancer

United States
Credit Valley EyeCare
Canadian Glaucoma Clinical Research Council

Unknown

Effect of Prophylactic Aqueous Suppression on Hyperencapsulation of Ahmed Glaucoma Valves

Glaucoma

Canada
Stanford University

Completed

Xyrem(Sodium Oxybate) and Ambien(Zolpidem Tartrate) in the Treatment of Chronic Insomnia.

Sleep Initiation and Maintenance Disorders

United States
Massachusetts Eye and Ear Infirmary

Completed

Effect of Cosopt Versus Combigan on Retinal Vascular Autoregulation in Primary Open Angle Glaucoma (POAG)

Glaucoma

United States
Sunovion

Completed

Efficacy Safety Study of Arformoterol/Tiotropium Combination Versus Either Therapy Alone in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease | Emphysema | Bronchitis

United States
Groupe D'Etude des Tumeurs Uro-Genitales

Completed

Mitoxantrone, Etoposide, and Vinorelbine As Second-Line Therapy in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy

Prostate Cancer

France
Astellas Pharma Singapore Pte. Ltd.

Completed

Treatment Persistence Among Patients With Overactive Bladder: A Retrospective Secondary Data Analysis in Asia Oceania

Overactive Bladder (OAB)

Korea, Republic of, Australia
Medical University of Vienna

Withdrawn

Effects of Common Topical Glaucoma Therapy on Optic Nerve Head Blood Flow Autoregulation During Increased Arterial Blood Pressure and Artificially Elevated Intraocular Pressure in Healthy Humans

Glaucoma

Austria
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets for Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Charleston Laboratories, Inc

Completed

A Controlled Study to Determine the Efficacy and Safety of CL-108 5 mg for Acute Pain and the Prevention of OINV

Pain | Nausea | Vomiting

United States
Merus N.V.

Completed

MCLA-128 With Trastuzumab/Chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer.

Breast Cancer Metastatic

United States, France, Belgium, Spain, United Kingdom, Netherlands, Portugal
Transcept Pharmaceuticals

Completed

Driving Performance After Middle of the Night Administration of 3.5 mg Zolpidem Tartrate Sublingual Tablet

Insomnia

Netherlands
Massachusetts General Hospital

Completed

Venlafaxine With or Without Zolpidem in Treating Hot Flashes and Associated Sleep Disorders in Women With Breast Cancer OR at High Risk for Developing Breast Cancer

Breast Cancer | Hot Flashes | Sleep Disorders

United States
Allergan

Completed

Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma

United States
Cephalon

Completed

A Study to Assess the Pharmacokinetics of the Hydrocodone Extended-Release Tablet (CEP-33237) in Subjects With Normal Renal Function and Subjects With Varying Degrees of Renal Impairment

Renal Impairment

United States
Niconovum USA
Inflamax Research Incorporated

Completed

Oral Mucosal Effects In Adult Smokers Associated With Two Nicotine Lozenge Formulations

Safety Issues

United States
Astellas Pharma Singapore Pte. Ltd.

Completed

A Registry Study of Patients Initiating a Course of Drug Therapy for Overactive Bladder in Taiwan, Korea and China

Overactive Bladder (OAB)

Korea, Republic of, Taiwan
Alcon Research

Completed

Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Evaluation of Intraocular Pressure Using Simbrinza™ in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Laboratorios Sophia S.A de C.V.

Terminated

Comparative Study of the Efficacy of Either Krytantek Ofteno PF® or Eliptic Ofteno PF® Plus Gaap Ofteno PF® for POAG or Ocular Hypertension. (PRO-122)

Ocular Hypertension | Glaucoma, Open-Angle

Mexico
Wake Forest University Health Sciences

Completed

The Effect of Brimonidine on Intraocular Pressure When Dilating Routine Patients

Intraocular Pressure

United States
Philadelphia Eye Associates
Pfizer

Completed

Study to Determine if Taking OTC Non-Steroidal Anti-Inflammatory Affects Eye Pressure in Patients Using Glaucoma Drops

Ocular Hypertension | Glaucoma

United States
National Cancer Institute (NCI)

Completed

Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma

Recurrent Childhood Rhabdomyosarcoma | Recurrent Adult Soft Tissue Sarcoma | Previously Treated Childhood Rhabdomyosarcoma | Adult Rhabdomyosarcoma | Childhood Alveolar Rhabdomyosarcoma | Childhood Pleomorphic Rhabdomyosarcoma | Childhood Rhabdomyosarcoma With Mixed Embryonal and Alveolar Features

United States, Canada, Australia, New Zealand
Nacuity Pharmaceuticals, Inc.

Recruiting

PK and PD Study of NPI-001 and Cysteamine Bitartrate (INCA)

Cystinosis

Australia
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Open-Label, Extension Study to Evaluate the Safety of Hydrocodone Bitartrate Extended-Release Tablets

Low Back Pain

United States
New Mexico Cancer Care Alliance

Completed

A Randomized Phase III Study of Vitamins B6 and B12 to Prevent Chemotherapy-Induced Neuropathy in Cancer Patients

Cancer

United States
Yale University
National Institute on Drug Abuse (NIDA); Nabi Biopharmaceuticals

Completed

Nicotine Vaccination and Nicotinic Receptor Occupancy

Nicotine Dependence

United States
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Efficacy and Safety of Tramadol HCl/Acetaminophen, Hydrocodone Bitartrate/Acetaminophen and Placebo in Patients With Pain From an Ankle Sprain With a Partial Torn Ligament

Pain | Sprains and Strains
Zhejiang University

Unknown

Randomized Study of Gonadotropin-releasing-hormone Agonist (GnRH-a) or Expectant Management for Endometriosis

Endometriosis

China
Royal Marsden NHS Foundation Trust

Completed

Comparison of Three Combination Chemotherapy Regimens in Treating Women With Stage I or Stage II Breast Cancer

Breast Cancer

United Kingdom
Duke University
Genentech, Inc.

Terminated

A Phase II Safety and Tolerability Study of Bevacizumab When Added to Single-agent Chemotherapy to Treat Patient With Breast Cancer Metastatic to Brain

Breast Cancer

United States
Laboratorios Sophia S.A de C.V.

Recruiting

PRO-122 Versus Concomitant Therapy in Subjects With Uncontrolled Primary Open-angle Glaucoma (PRO-122LATAM) (PRO-122LATAM)

Primary Open-angle Glaucoma

Colombia, Mexico
Skin Laser & Surgery Specialists
Galderma R&D

Terminated

Mirvaso® Gel and Dysport® for Erythema and Flushing of Rosacea

Erythema and Flushing Associated With Rosacea
Optall Vision

Completed

Compound to Control Presbyopia Symptoms

Presbyopia

Mexico
The Cleveland Clinic

Completed

Effects of Choline From Eggs vs. Supplements on the Generation of TMAO in Humans (EGGS)

Cardiovascular Risk Factor

United States
University of Miami

Withdrawn

Rituximab, Gemcitabine, and Vinorelbine in Treating Patients With Hodgkin Lymphoma That Has Relapsed or Not Responded to Treatment

Lymphoma

United States
University of Kansas Medical Center
National Institute on Drug Abuse (NIDA)

Completed

Individualizing Pharmacotherapy for African American Smokers

Smoking Cessation

United States
Creighton University

Unknown

Rate Control in Atrial Fibrillation

Atrial Fibrillation

United States
University Hospital Inselspital, Berne
University of Zurich; University of Bern; Aalborg University

Completed

Linking Altered Central Pain Processing and Genetic Polymorphism to Drug Efficacy in Chronic Low Back Pain (Predictio) (Predictio)

Low Back Pain

Switzerland

3

Subscribe