Search clinical trials for: Aflibercept [Eylea]

Total 503 results

Panhandle Eye Group, LLP

Completed

Preoperative Bevacizumab and Ziv-Aflibercept Administration in PDR Subjects Undergoing PPV

Diabetic Retinopathy

Mexico
Sandoz

Completed

Phase III Study Assessing the Efficacy, Safety and Immunogenicity of SOK583A1 Versus Eylea® in Patients With Neovascular Age-related Macular Degeneration (Mylight)

Neovascular Age-related Macular Degeneration

United States, Bulgaria, Czechia, Australia, Austria, France, Germany, Hungary, Israel, Japan, Latvia, Lithuania, Poland, Portugal, Slovakia, Spain
National Cancer Institute (NCI)

Terminated

Ganetespib and Ziv-Aflibercept in Refractory Gastrointestinal Carcinomas, Non-Squamous Non-Small Cell Lung Carcinomas, Urothelial Carcinomas, and Sarcomas

Neoplasms

United States
EyePoint Pharmaceuticals, Inc.

Not yet recruiting

Study of EYP-1901 in Patients With Diabetic Macular Edema (DME) (VERONA)

Diabetic Macular Edema
Southeast Retina Center, Georgia
Regeneron Pharmaceuticals

Unknown

Intravitreal Aflibercept for Neovascular Polypoidal Choroidal Vasculopathy (RIVAL Trial) (RIVAL)

Neovascular Polypoidal Choroidal Vasculopathy

United States
Regeneron Pharmaceuticals
Bayer

Completed

Safety and Efficacy of Repeated Intravitreal Administration of Vascular Endothelial Growth Factor (VEGF) Trap in Patients With Wet Age-Related Macular Degeneration (AMD)

Macular Degeneration

United States
Sanofi
Regeneron Pharmaceuticals

Terminated

Aflibercept Compared to Placebo in Term of Efficacy in Patients Treated With Gemcitabine for Metastatic Pancreatic Cancer (VANILLA)

Pancreatic Neoplasm

United States, France, Canada, Poland, Romania, Russian Federation, Germany, Italy, Spain, Switzerland, Bulgaria, India, Belgium, Czech Republic, Mexico, Argentina, Hungary, Colombia, Slovakia, Chile, Austria, Greece, Puerto Rico, Cyprus
Retina Clinic, Sao Paulo, Brazil
Federal University of São Paulo

Completed

Intravitreal Injections of Ziv-aflibercept for Macular Diseases

Diabetic Macular Edema | Age Related Macular Degeneration | Central Retinal Vein Occlusion With Macular Edema | Branch Retinal Vein Occlusion With Macular Edema

Brazil
National Cancer Institute (NCI)

Terminated

Aflibercept for Relapsed Multiple Myeloma

Stage II Multiple Myeloma | Stage III Multiple Myeloma

United States
Azienda Ospedaliera Universitaria Policlinico Paolo...

Completed

Treatment of Polypoidal Choroidal Vasculopathy in Pachychoroid

Choroidal Neovascularization | Choroid Disease

Italy
John Strickler, M.D.
Sanofi

Completed

Phase I/II Study of Capecitabine Plus Aflibercept to Treat Metastatic Colorectal Cancer (X-TRAP)

Metastatic Colorectal Cancer

United States
Duke University
Bausch & Lomb Incorporated

Withdrawn

Adjunctive Photodynamic Therapy + Aflibercept vs. Afilbercept Alone for PDA in NV AMD

Neovascular Age-related Macular Degeneration

United States
Kyoto University, Graduate School of Medicine

Recruiting

Cohort Study of the Clinical Course of Macular Diseases in Japanese

Macular Disease

Japan
Fondation Ophtalmologique Adolphe de Rothschild
Bayer

Active, not recruiting

Spontaneous Retinal Artery Pulses (SPARs) as a Prognostic Determinant of Central Retinal Vein Occlusions (CRVO) in Patients With or Without Intravitreal Aflibercept Injections (PULSOV)

Central Retinal Vein Occlusion

France
Jules Bordet Institute

Completed

Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancers (MOMENTUM1)

Metastatic Colorectal Cancers | Metastatic Gastric Cancers | Metastatic Oesophageal Cancers | Metastatic Pancreatic Cancers | Metastatic Biliary Cancers | Metastatic Breast Cancers

Belgium
Vitreous -Retina- Macula Consultants of New York

Completed

To Evaluate The Role of Intravitreal Aflibercept Injection (2.0 mg) in the Management of Previously Treated Patients With Exudative AMD

AMD (With Persistent or Recurrent Fluid Despite Monthly Intravitreal Anti-VEGF Therapy)

United States
Regeneron Pharmaceuticals
Bayer

Completed

Vascular Endothelial Growth Factor VEGF Trap-Eye:Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration(AMD) (VIEW1)

Macular Degeneration

United States, Canada
European School of Advanced Studies in Ophthalmology

Completed

Diabetic Macular Edema: Relevance of Staging Progression on Therapeutic Outcome

Diabetic Macular Edema

Switzerland
National Cancer Institute (NCI)

Completed

Ziv-Aflibercept in Treating Patients With Metastatic or Unresectable Kidney Cancer

Metastatic Renal Cell Carcinoma

United States, Peru
Uptown Eye Specialists

Not yet recruiting

Ozurdex in Suboptimal Diabetic Macular Edema Patients (DME)

Diabetic Macular Edema
National Cancer Institute (NCI)

Completed

VEGF Trap and Docetaxel in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

Fallopian Tube Cancer | Recurrent Ovarian Epithelial Cancer | Malignant Tumor of Peritoneum

United States
Aston University
University of Worcester

Completed

Non-Pharmaceutical Treatment of Seasonal Allergic Conjunctivitis

Hypersensitivity

United Kingdom
SCRI Development Innovations, LLC
Sanofi

Completed

5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer

Rectal Cancer

United States
Ocular Therapeutix, Inc.

Active, not recruiting

CLN-0046: Treatment of AMD Subjects With OTX-TKI

Neovascular Age-related Macular Degeneration

Australia
Sanofi
Regeneron Pharmaceuticals

Completed

A Phase I Study of Intravenous Aflibercept in Combination With Docetaxel in Japanese Cancer Patients

Neoplasms

Japan
Massachusetts Eye and Ear Infirmary
Regeneron Pharmaceuticals

Recruiting

Anti-VEGF Therapy for Acute Thyroid Eye Disease (AcTED)

Thyroid Eye Disease

United States
National Cancer Institute (NCI)

Completed

S0802 - Topotecan With or Without Aflibercept in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Extensive Stage Small Cell Lung Cancer | Recurrent Small Cell Lung Cancer

United States
Sanofi
Regeneron Pharmaceuticals

Terminated

Study of Aflibercept as Maintenance Therapy Following Induction With Aflibercept in Combination With XELOX, as First-Line Treatment for Metastatic Colorectal Cancer Patient (AMOR)

Colorectal Cancer Metastatic

Italy
Sanofi
Regeneron Pharmaceuticals

Completed

A Study of Intravenous Aflibercept With Docetaxel in Chinese Patients With Solid Tumors

Neoplasm Malignant

China
Sanofi
Regeneron Pharmaceuticals

Withdrawn

Capecitabine Plus Aflibercept as Maintenance Therapy Following Capecitabine Plus Oxaliplatin Plus Aflibercept in Patients With Metastatic Colorectal Cancer (Drop and Go)

Colorectal Cancer Metastatic
National Cancer Institute (NCI)

Completed

Belinostat in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Adult Primary Hepatocellular Carcinoma

United States, Singapore
National Cancer Institute (NCI)

Completed

Belinostat (PXD101) to Treat Tumors of the Thymus at an Advanced Stage

Thymic Carcinoma | Thymoma

United States
Aerie Pharmaceuticals
Alcon Research

Recruiting

Study of AR-14034 in Participants With Neovascular Age-Related Macular Degeneration (nAMD) (NOVA-1)

Neovascular Age-related Macular Degeneration (nAMD)

United States
Medical College of Wisconsin
University of Wisconsin, Milwaukee

Completed

Photobiomodulation for the Treatment of Diabetic Macular Edema (PTDME)

Diabetic Retinopathy

United States
Neurotech Pharmaceuticals

Terminated

Study of the Intravitreal Implantation of NT-503-3 Encapsulated Cell Technology (ECT) for the Treatment of Recurrent Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)

Macular Degeneration

United States, Israel
National Cancer Institute (NCI)

Completed

Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor

United States
Svendborg Hospital
Odense University Hospital

Unknown

Polymyalgia Rheumatica and Giant Cell Arteritis

Giant Cell Arteritis | Polymyalgia Rheumatica

Denmark
Jaeb Center for Health Research
National Eye Institute (NEI); Genentech, Inc.; Regeneron Pharmaceuticals

Completed

Comparative Effectiveness Study of Intravitreal Aflibercept, Bevacizumab, and Ranibizumab for Diabetic Macular Edema (Protocol T)

Diabetic Macular Edema

United States
Sanofi
Regeneron Pharmaceuticals; NSABP Foundation Inc

Completed

Aflibercept Versus Placebo in Combination With Irinotecan and 5-FU in the Treatment of Patients With Metastatic Colorectal Cancer After Failure of an Oxaliplatin Based Regimen (VELOUR)

Neoplasm Metastasis | Colorectal Neoplasms

Italy, Austria, Estonia, Spain, South Africa, Belgium, Puerto Rico, United Kingdom, Sweden, United States, Argentina, Australia, Brazil, Chile, Czech Republic, Denmark, France, Germany, Greece, Korea, Republic of, Netherlands, New... and more
National Nutrition and Food Technology Institute

Unknown

The Effects of Hesperidin and Flaxseed on Biochemical Factors and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease

Non Alcoholic Steatohepatitis

Iran, Islamic Republic of
Rophibio, Inc.

Not yet recruiting

A Phase 3 Clinical Trial to Compare RBS-001 to Eylea® in Subjects With Neovascular Age-Related Macular Degeneration

Neovascular Age-related Macular Degeneration (nAMD)

United States
Innovent Biologics (Suzhou) Co. Ltd.

Suspended

Evaluation of IBI302 Injection in nAMD or DME

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

China
Per Hellström
University of Helsinki; CTC Clinical Trial Consultants AB; Biohit Oyj, Helsinki... and other collaborators

Completed

L-cysteine Prevents Stomach Exposure to Carcinogenic Acetaldehyde

Gastritis, Atrophic

Sweden
Peking University Cancer Hospital & Institute

Unknown

Evaluating 18F-FDG PET/CT With Liver SUVmax-based Criteria for Prognosis of Patients With Diffuse Large B-cell Lymphoma

Lymphoma, Large B-Cell, Diffuse

China
Clearside Biomedical, Inc.

Completed

Safety and Tolerability Study of Suprachoroidal Injection of CLS-AX Following Anti-VEGF Therapy in Neovascular AMD (OASIS)

Neovascular Age-related Macular Degeneration

United States
Sudhalkar Eye Hospital

Not yet recruiting

Anti-VEGF Therapy Versus Dexamethasone Implant for DME

Clinically Significant Macular Edema Due to Diabetes Mellitus

Germany
Ophthotech Corporation

Completed

A Study to Establish the Safety and Tolerability of Zimura® (Anti-C5 Aptamer) in Combination With Anti-VEGF Therapy in Subjects With Idiopathic Polypoidal Choroidal Vasculopathy (IPCV)

Idiopathic Polypoidal Choroidal Vasculopathy

United States
University of Athens

Completed

Aflibercept for Diabetic Macular Edema In Real-life Practice in GREece (ADMIRE)

Diabetic Macular Edema

Greece
Hospices Civils de Lyon

Completed

Study Evaluating the Efficacy of Aflibercept for the Treatment of Inflammatory CNV in Young Patients (ALINEA). (ALINEA)

Inflammatory Choroidal Neovascularization

France
University Hospital Muenster

Completed

Aflibercept in Patients With Pigment Epithelial Detachments (PED)

Pigment Epithelial Detachment

Germany

Search clinical trials for: Aflibercept [Eylea]

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Trinidad & Tobago

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations