Search clinical trials for: Arm 1: NTLA-5001

Total 889 results

Janssen Vaccines & Prevention B.V.

Completed

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Ad26.ZIKV.001 in Healthy Adult Volunteers

Healthy

United States
Sintetica SA

Recruiting

The Efficacy and Safety of Chloroprocaine 1% and 2% in Pediatric Population

Hernia, Inguinal | Flat Foot

Italy, Spain
ImmunoFrontier, Inc.

Completed

Safety Study of a Recombinant Protein Vaccine to Treat Esophageal Cancer

Esophageal Cancer

Japan
University of Utah
National Institute of Nursing Research (NINR)

Recruiting

Maternal Mental Health Access - MaMa (MaMa)

Postpartum Depression | Perinatal Depression

United States
Digestome Therapeutics

Completed

A First in Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of DGX-001

Depressive Disorder

Australia
Imunon

Completed

Study of Safety & Biological Activity of IP IMNN-001 (Also Known as GEN-1) With Neoadjuvant Chemo in Ovarian Cancer

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

United States
Eisai Inc.

Completed

A Study to Characterize Pharmacokinetics (PK) and Pharmacodynamics (PD) of LUSEDRA® Administered as Continuous Infusion or Bolus Compared With Continuous Infusion of Propofol Injectable Emulsion

Monitored Anesthesia Care

United States
Central Institute of Mental Health, Mannheim
German Research Foundation

Completed

Hydrocortisone in the Treatment of Intrusions in Patients With Posttraumatic Stress Disorder

Posttraumatic Stress Disorder

Germany
Ohio State University
Vidatak, LLC

Completed

Vidatalk Communication Application: Usability, Acceptability and Efficacy Study

Critical Illness | Nonverbal Communication

United States
Longbio Pharma

Active, not recruiting

A Study of Single and Multiple Dose Administration of LP-001 in Healthy Subjects

Myelodysplastic Syndrome (MDS)

China
Handok Inc.

Completed

Dose Proportionality Study Comparing Amaryl-M 1/500 mg and Amaryl-M 2/500 mg

Healthy
Medtronic - MITG
Institute for Skin Research, Israel

Completed

Comfort Check of CO2 Monitoring Cannulas With Oxygen Delivery

Wearing Comfort

Israel
Case Comprehensive Cancer Center

Completed

C-FLASH (Cigarillo Flavor and Abuse Liability, Attention, and Substitution in youtH)

Smoking Behaviors

United States
Mayo Clinic

Completed

Acetaminophen Transfer Across the Placenta and the Assessment of Fetal Well-being

Fetal Testing | Transplacental Transfer of Acetaminophen

United States
Shanghai Cell Therapy Research Institute

Unknown

CTLA-4 and PD-1 Antibodies Expressing Mesothelin-CAR-T Cells for Mesothelin Positive Advanced Solid Tumor

Advanced Solid Tumor

China
Assistance Publique - Hôpitaux de Paris

Completed

Evaluation of OMEGAVEN 10%® (n-3 EFA Lipid Emulsion) in Home Parenteral Nutrition-associated Liver Disease (MEGANORM)

Liver Diseases

France
Teikoku Pharma USA, Inc.

Completed

Flurbiprofen Tape for Treatment of Chronic Low Back Pain (LBP)

Chronic Low Back Pain

United States
Pfizer
AbbVie

Not yet recruiting

A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH) (CHERISH)

Gram-negative Bacterial Infection
M.D. Anderson Cancer Center
National Cancer Institute (NCI); United States Department of Defense; National...

Recruiting

PROSPECT - Profiling of Resistance Patterns & Oncogenic Signaling Pathways in Evaluation of Cancers of the Thorax and Therapeutic Target Identification

Lung Cancer | Cancer of Thorax

United States
Taiho Oncology, Inc.

Terminated

Diffuse Gastric and Esophagogastric Junction Cancer S-1 Trial (DIGEST)

Metastatic Diffuse Gastric Cancer Including Carcinoma of the Gastro-esophageal Junction

Belgium, Spain, United States, Italy, Estonia, Russian Federation, Bulgaria, Hungary, Croatia, Israel, Mexico, Poland, Portugal, Romania, South Africa, Ukraine, United Kingdom, Brazil, Germany, Argentina
Clinical Hospital Centre Zagreb
Merck Sharp & Dohme LLC

Completed

Natriuretic Effect of GLP-1in Healthy Non Obese Subjects

Sodium Excretion by Urination

Croatia
Instituto de Investigación Marqués de Valdecilla

Withdrawn

Efficacy, Safety, and Immunogenicity of Vaccine Reimmunization With a Third Homologous Versus Heterologous Dose Against COVID-19 in Patients Undergoing Solid Organ Transplantation. (REIN-TX)

Covid19

Spain
University of Pennsylvania

Active, not recruiting

Stimulant Overdose in the Medicaid Population: Who is at Risk, and When Are They at Risk

Stimulant Overdose

United States
Takeda

Recruiting

Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

Alpha1-Antitrypsin Deficiency

Italy, United States, Poland, Portugal
Bateman Horne Center

Recruiting

Valacyclovir Plus Celecoxib for Post-Acute Sequelae of SARS-CoV-2 (PASC)

Long COVID | PASC Post Acute Sequelae of COVID 19

United States
Hospital de Clinicas Caracas

Unknown

Meal Timing on Glucose and Hyperandrogenism in PCOS Women (MealTimePCOS)

Polycystic Ovary Syndrome (PCOS) Women

Venezuela
Hospital Privado de Cordoba, Argentina

Completed

Metformin and Lifestyle Intervention in Women With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome

Argentina
Zhongshan Hospital Xiamen University
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Not yet recruiting

Camrelizumab Combined With Intraperitoneal Infusion of Nab-paclitaxel, Intravenous Chemotherapy and S-1 in the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis：Single-arm, Prospective Clinical Study

Stage IV Gastric Cancer With Metastasis
Philogen S.p.A.
Eudax S.r.l.

Terminated

Clinical Study Phase II of L19IL2 in Combination With Dacarbazine in Patients With Metastatic Melanoma

Metastatic Melanoma

Switzerland, Italy, Austria, Germany
Mohamed Sayed Abdelhafez

Recruiting

Use of Warfarin After the First Trimester in Pregnant Women With APS

Recurrent Miscarriage | Antiphospholipid Syndrome

Egypt
Sintetica SA

Completed

Chloroprocaine 3% Gel Eye Drop as Topical Anestheticsin Phacoemulsification.

Cataract

Italy, Slovakia, Spain
Manchester University NHS Foundation Trust
National Institute for Health Research, United Kingdom

Recruiting

Endoscopically-delivered Purastat to Treat Bleeding Caused by Radiation Proctopathy (PURASTAT)

Radiation Proctopathy

United Kingdom
The Cleveland Clinic

Completed

Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection

Overactive Bladder | Urge Incontinence | Urinary Incontinence, Urge | Overactive Bladder Syndrome

United States
MinaPharm Pharmaceuticals

Unknown

Trial Comparing the Efficacy, Tolerability and Safety Between Three Arms in Treatment of HCV in Egyptian Population (Quadritherapy)

Chronic Hepatitis c

Egypt
Harvard Pilgrim Health Care
Centers for Disease Control and Prevention; University of California, Irvine; University of Massachusetts, Amherst and other collaborators

Completed

Mupirocin-Iodophor ICU Decolonization Swap Out Trial

Staphylococcus Aureus

United States
ARS Pharmaceuticals, Inc.

Active, not recruiting

Safety and Efficacy of Intranasal Epinephrine After Administration of ARS -1 in Subjects With Frequent Urticaria Flares

Urticaria

United States
Takeda
Takeda Development Center Americas, Inc.

Recruiting

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

Alpha1-Antitrypsin Deficiency

United States, Belgium, Switzerland, Canada, Australia, Germany, United Kingdom, Austria, France, Spain, Portugal, Italy, Poland, Brazil
University of Washington
National Institute of Mental Health (NIMH); Bill and Melinda Gates Foundation; Kenya Medical Research Institute and other collaborators

Completed

The Partners Scale-Up Project

HIV-1-infection

Kenya
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With High-Risk Stage III or Completely Resected Metastatic Melanoma

Recurrent Melanoma | Stage IV Melanoma | Stage III Melanoma
The Lymphoma Academic Research Organisation

Recruiting

Mosunetuzumab-Lenalidomide Versus Investigator Choices in Patients With Relapsed or Refractory Marginal Zone Lymphoma

Marginal Zone Lymphoma

France
Actimed Therapeutics Ltd
Quotient Sciences

Completed

Study of Comparative Bioavailability and Pharmacokinetics of ACM-001.1) and Pindolol in Healthy Volunteers (HV)

Cachexia

United Kingdom
Celularity Incorporated

Terminated

Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM (CYNK001GBM01)

Glioblastoma Multiforme | Molecular Mechanisms of Pharmacological Action | Giant Cell Glioblastoma | Astrocytoma, Grade IV | Physiological Effects of Drugs | Peripheral Nervous System Agents | Analgesics | Analgesics, Non-narcotic | Cyclophosphamide | Immunosuppressive Agents | Immunologic Factors | Antiviral... and other conditions

United States
LiuYing

Not yet recruiting

Cadonilimab as Neoadjuvant Therapy in Resectable Stage II-III MSI-H/dMMR Colorectal Cancer (MSI-H/dMMR)

Colorectal Cancer | Neoadjuvant Therapy | Mismatch Repair-deficient (dMMR) | Microsatellite Instability-high (MSI-H)

China
Hamad Medical Corporation

Completed

Caffeine Citrate for the Treatment of Apnea Associated With Bronchiolitis in Young Infants

Apnea | Bronchiolitis | Caffeine

Qatar
Celgene

Completed

A Study of Perpetrator Drug Interactions of Enasidenib in AML Patients

Leukemia, Myeloid, Acute

Korea, Republic of, Australia
Hospital General "Dr. Miguel Silva" de Morelia
Universidad Nacional Autonoma de Mexico; NAUSLIFE HEMODIALYSIS CLINICS

Unknown

Bicarbonate vs Heparin Catheter Lock in Chronic Hemodialysis Patients (BICATH)

End Stage Renal Disease | Hemodialysis Access Failure | Vascular Access Complication | Catheter Complications | Hemodialysis Catheter Infection

Mexico
Fudan University

Recruiting

PD-1 Inhibitor Plus Anti-EGFR Therapy And Radiotherapy in Locally Advanced NPC Resistant to Induction Chemotherapy

Nasopharyngeal Carcinoma

China
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Clinical Trial to Evaluate the Safety and Immunogenicity of Ferritin Nanoparticles Expressing Native-like HIV-1 Envelope Trimers Followed by Boost With mRNA Lipid Nanoparticles Encoding a Native-like HIV-1 Envelope Trimer in Adults Without HIV

Hiv

United States
Dartmouth-Hitchcock Medical Center

Recruiting

Healthy Homes Study (HHS)

Lung Cancer | Home Air Radon Testing

United States
Merz North America, Inc.

Completed

Multicenter Study of the Safety and Efficacy of NAFT-500 in Tinea Pedis

Tinea Pedis | Athlete's Foot

United States

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