Search clinical trials for: BCD-089, 162 mg, s/c, q2w

Total 97 results

Biocad

Completed

The BCD-089 (aIL6R) in Patients With Active Rheumatoid Arthritis (AURORA)

Seropositive RA

Russian Federation, Belarus
Biocad

Completed

An International Multicenter, Randomized, Double-blind, Placebo-Controlled Clinical Study of Efficacy and Safety of Two Dosing Regimens of BCD-085 (JSC BIOCAD, Russia) in Patients With Moderate to Severe Plaque Psoriasis (BCD-085-7)

Moderate to Severe Plaque Psoriasis

Russian Federation
Shionogi

Completed

Phase IIb One Year Efficacy and Safety Study of S-2367 in Obese Subjects With Initial 6-Week Low Calorie Diet

Obesity

United States
Merck Sharp & Dohme LLC

Completed

Safety, Pharmacodynamics, and Pharmacokinetics of Different Dosing Regimens of MK-8266 in Participants With Hypertension (MK-8266-008)

Hypertension
GlaxoSmithKline

Terminated

A Study to Evaluate Single and Repeat Doses of IV GSK2251052 in Healthy Male Japanese and Caucasian Subjects and Repeat Doses of Supratherapeutic Doses of IV GSK2251052 in Healthy Volunteers

Community-acquired Infection

United States
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MK8266 in Hypertensive Men (MK-8266-002)

Hypertension
Biocad

Active, not recruiting

Comparative Study of the Efficacy and Safety of BCD-132 With Teriflunomide and Placebo in Multiple Sclerosis

Multiple Sclerosis

Russian Federation
Novartis

Completed

A Study of Valsartan Administered Once Daily Versus Twice Daily, in Patients With Stable, Chronic Heart Failure

Chronic Heart Failure

United States
Breath of Life International Pharma Ltd

Completed

A Phase I Open Label Study to Assess PK and Safety of Plant Cannabis Extract

Healthy

Israel
Vanderbilt University

Completed

Comparative Effects of Aspirin and NHP-544C

Healthy

United States
Zhejiang Haichang Biotech Co., Ltd.

Not yet recruiting

Phase 2 Study of WGI-0301 in Combination With Sorafenib for Advanced HCC

Advanced Hepatocellular Carcinoma (HCC)
Jiuda Zhao
Second Hospital of Lanzhou University

Recruiting

A Study to Evaluate the Efficacy and Safety of Sintilimab Plus Apatinib and Chemotherapy in Patients With HER-2 Negative Microsatellite Stability (MSS) Advanced or Metastatic Gastric (GC) or Gastroesophageal Junction (GEJ) Cancer

Gastric Cancer | Chemotherapy | Immunotherapy

China
UroGen Pharma Ltd.

Completed

Safety of Pre-TURBT Intravesical Instillation of Escalating Doses of TC-3 Gel and MMC in NMIBC Patients

Neoplasms | Urologic Diseases | Urinary Bladder Diseases | Bladder Cancer

Israel
Enteris BioPharma Inc.
Syneos Health; Parexel

Recruiting

Study to Evaluate the Pharmacodynamics and Efficacy of Leuprolide Tablets (Ovarest®) in Women With Endometriosis

Endometriosis

United States
Tonix Pharmaceuticals, Inc.

Completed

Comparative Pharmacokinetics and Safety of 3 Different Formulations of TNX-102 2.8 mg SL Tablets and Cyclobenzaprine 5 mg Oral Tablet in Healthy Adults

Healthy Adults

Canada
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

First in Human Study of M4344 in Participants With Advanced Solid Tumors

Solid Tumor | Advanced Solid Tumor

Spain, United States, Netherlands, United Kingdom
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Effect of Dose on the Pharmacokinetics of OROS Hydromorphone Under Fasted Conditions in Healthy Taiwanese Participants

Healthy Volunteers

Taiwan
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Intravenous JNJ-64179375 Versus Oral Apixaban in Participants Undergoing Elective Total Knee Replacement Surgery (TEXT-TKR)

VTE Prophylaxis With Anticoagulation After Total Knee Replacement Surgery

Belgium, Italy, Malaysia, Latvia, Spain, Turkey, Bulgaria, United States, Lithuania, Russian Federation, Ukraine, Japan, Argentina, Brazil, Canada, Poland
Merck Sharp & Dohme LLC

Terminated

A Study of the Safety, Tolerance, and Pharmacokinetics of Oral Posaconazole in Immunocompromised Children (P03579)

Fungal Infections
Eleonora Seelig

Completed

Acute Consequences Of Food-induced Glucocorticoid Secretion In Healthy Individuals (Gluco-Feed)

Glucocorticoid Effect

Switzerland
Fujian Provincial Hospital

Completed

Esketamine-propofol Versus Propofol for Flexible Bronchoscopy

Postoperative Recovery

China
Azienda Ospedaliero-Universitaria Careggi
Azienda USL Toscana Centro

Active, not recruiting

Effect of Micronutrient Supplementation on the Intestinal Microbiota in Patients With Age-related Macular Degeneration - The Gut-Retina-axis Study

Age-Related Macular Degeneration

Italy
National Cancer Institute (NCI)

Active, not recruiting

Copanlisib Hydrochloride and Nivolumab in Treating Patients With Recurrent or Refractory Diffuse Large B-cell Lymphoma or Primary Mediastinal Large B-cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal Large B-Cell Lymphoma | Refractory Primary Mediastinal Large B-Cell Lymphoma

United States
Advanced Circulatory Systems
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With an Inspiratory Impedance Device, and Standard CPR With an Intrathoracic Pressure Regulator During Out-of-hospital Cardiac Arrest

Cardiac Arrest | Sudden Cardiac Death

United States
University Medicine Greifswald
AWD.pharma GmbH & Co. KG

Completed

Pharmacokinetics, Metabolism and Analgesic Effects of Flupirtine

Pain | Pharmacokinetics | Flupirtine

Germany
Kamari Pharma Ltd

Recruiting

Study Designed to Evaluate Safety and Efficacy of 1% Topical Formulation of KM-001 on Type 1 Punctate Palmoplantar Keratoderma or Pachyonychia Congenita Diseases

Pachyonychia Congenita | Punctate Palmoplantar Keratoderma Type 1

Israel
Eleonora Seelig

Recruiting

The Role of Glucocorticoids to Maintain Energy Homeostasis During Starvation (Gluco-Starve)

Glucocorticoid Effect

Switzerland
Massachusetts General Hospital
BrainCells Inc.

Completed

Efficacy and Safety Study of a Combination Product [Drug:BCI-024 (Buspirone) and Drug:BCI-049 (Melatonin)] to Treat Major Depressive Disorder (MDD)

Major Depressive Disorder

United States
Bayer

Completed

Prevention of Sagopilone-induced Neurotoxicity With Acetyl-L-Carnitine (ALC)

Ovarian Cancer | Prostate Cancer

Italy, Belgium, Netherlands, France, Germany, United Kingdom
University of Texas Southwestern Medical Center
National Center for Research Resources (NCRR)

Completed

Safety and Efficacy of Fluoxetine in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States
Kamari Pharma Ltd

Recruiting

Assessment of KM-001 - Safety, Tolerability, and Efficacy in Patients With PPPK1 or PC

Pachyonychia Congenita | Punctate Palmoplantar Keratoderma Type 1

United Kingdom
National Cancer Institute (NCI)

Recruiting

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

HIV Infection | Anal Squamous Cell Carcinoma | Anal Canal Cloacogenic Carcinoma | Stage III Anal Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Anal Margin Squamous Cell Carcinoma | AIDS-Related Anal Carcinoma | Rectal Squamous Cell Carcinoma | Stage I Anal Cancer AJCC... and other conditions

United States
Samsung Medical Center

Completed

Pharmacodynamic Drug Interaction Between Cilostazol and Statins (SMCCPT-100)

Healthy

Korea, Republic of
University of Rome Tor Vergata
University of L'Aquila

Completed

Sequential Bacillus Calmette-Guérin (BCG) and Electromotive Mitomycin-C Versus Bacillus Calmette-Guérin (BCG) Alone for High Risk Superficial Bladder Cancer (BCG/EMDA-MMC)

Bladder Cancer

Italy
Boehringer Ingelheim

Completed

EARLY 3-months Aggrenox Treatment Started Within 24 Hrs of Ischemic Stroke Onset vs. After One Week 100 mg ASA

Cerebrovascular Accident

Germany
National Cancer Institute (NCI)

Recruiting

Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung Cancer

Extensive Stage Lung Small Cell Carcinoma | Limited Stage Lung Small Cell Carcinoma | Platinum-Resistant Lung Small Cell Carcinoma | Platinum-Sensitive Lung Small Cell Carcinoma | Recurrent Lung Small Cell Carcinoma

United States
Clinica Universidad de Navarra, Universidad de...
University of Navarrra Hospital (Clinica Universitaria)

Unknown

Concentration of Antimicrobials in Catheter-lock Solutions (CONAN)

Catheter-Related Infections | Bacteremia.

Spain
donald whiting
Boston Scientific Corporation

Recruiting

Deep Brain Stimulation Effects in Patients With Chronic Refractory Obesity

Obesity

United States
Huai'an First People's Hospital
The Affiliated Hospital of Xuzhou Medical University; The First People's Hospital... and other collaborators

Recruiting

A Clinical Study Evaluating the Safety and Efficacy of ZRMT Regimen in the Treatment of PCNSL

Primary Central Nervous System Lymphoma

China
Wuhan Union Hospital, China

Withdrawn

Prophylactic Effects of Esketamine in Surgical Patients

Surgical Injury

China
National Institute of Allergy and Infectious Diseases...
ViiV Healthcare; Mylan Inc.

Recruiting

Pharmacokinetics and Safety of Double-dose Dolutegravir When Used With Rifapentine for HIV-associated Tuberculosis

HIV-associated Tuberculosis

South Africa, Thailand
University of Tennessee Medical Center

Withdrawn

Impedance Cardiography to Decrease the Risk of Preeclampsia

Preeclampsia | Chronic Hypertension Complicating Pregnancy (Diagnosis)

United States
Hospital Universitari de Bellvitge

Terminated

Continuation Electroconvulsive Therapy (C-ECT) for Relapse Prevention in Major Depression

Depression

Spain
National Cancer Institute (NCI)

Suspended

Testing the Addition of an Anti-cancer Drug, ASTX727 (Cedazuridine, Decitabine), to Chemotherapy (Paclitaxel) and Immunotherapy (Pembrolizumab) for Metastatic Triple-Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma | Unresectable Triple-Negative Breast Carcinoma

United States
Rigshospitalet, Denmark
Glostrup University Hospital, Copenhagen

Completed

The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients

Chronic Pain | Postoperative Pain | Analgesics

Denmark
National Cancer Institute (NCI)

Active, not recruiting

Cisplatin/Carboplatin and Etoposide With or Without Nivolumab in Treating Patients With Extensive Stage Small Cell Lung Cancer

Extensive Stage Lung Small Cell Carcinoma | Recurrent Lung Small Cell Carcinoma

United States
Planned Parenthood League of Massachusetts
Society of Family Planning

Completed

Cervical Preparation Before Dilation and Evacuation

Abortion, Induced

United States
Netherlands Institute for Pigment Disorders
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Completed

Fractional Laser Assisted Delivery of Anesthetics

Local Anesthesia of the Skin.

Netherlands
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Immunotherapy (Nivolumab With or Without Ipilimumab) in Patients With Advanced Solid Cancers That Have Changes in the Following Genes: PIK3CA and PTEN

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Canada
National Cancer Institute (NCI)

Completed

Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States, Israel

Search clinical trials for: BCD-089, 162 mg, s/c, q2w

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