Search clinical trials for: Baclofen IR

Total 461 results

Reckitt Benckiser LLC

Completed

Safety and Efficacy of Mucinex and IR Guaifenesin the Treatment of Symptoms of Acute Upper Respiratory Tract Infections

Acute Upper Respiratory Tract Infection

United States
UCB Pharma

Completed

Crossover Study of Neuropsychological Effects of Lacosamide and Carbamazepine Immediate Release in Healthy Subjects

Healthy

United States
GlaxoSmithKline

Terminated

Clinical Evaluation of Ropinirole IR (Immediate Release) Tablets in Patients Who Are Diagnosed With Symptomatic Restless Legs Syndrome (RLS) Associated With Chronic Kidney Disease (CKD) Managed With Haemodialysis (Including Haemofiltration and Haemodiafiltration)

Restless Legs Syndrome

Japan
Mundipharma Research Limited

Terminated

A Study Assessing the Efficacy and Safety of Lodotra® Compared to Prednisone IR in Subjects Suffering From PMR

Polymyalgia Rheumatica

United Kingdom
Dinora, Inc.
PharPoint Research, Inc.; Analgesic Solutions

Terminated

Delayed Release Prednisone in PMR

Polymyalgia Rheumatica

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

8-Week Study of Tolvaptan Dose Forms in Autosomal Dominant Polycystic Kidney Disease (ADPKD) (NOCTURNE)

Autosomal Dominant Polycystic Kidney Disease

United States
AstraZeneca

Completed

Study Comparing the Tolerability of Seroquel IR With Seroquel XR in Patients With Bipolar Depression

Bipolar Depression
Ensysce Biosciences

Completed

A Study to Evaluate the Intranasal Abuse Potential of PF614 in Non-Dependent Recreational Opioid Users

Recreational Drug Use

United States
Bristol-Myers Squibb

Completed

Multiple Dose Study In Cancer Patients: Safety and Tolerability of BMS-754807 in Combination With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Solid Tumors

Advanced Solid Tumors | Metastatic Solid Tumors

Korea, Republic of, Canada, Australia
National Institute on Alcohol Abuse and Alcoholism...

Completed

Baclofen for Treating Anxiety and Alcoholism

Alcohol Drinking | Alcohol Dependence | Alcoholism | Anxiety Disorder | Alcohol Drinking Related Problems

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Effect of Baclofen on Marijuana Withdrawal and Relapse

Marijuana Dependence

United States
Boehringer Ingelheim

Completed

Bioavailability of Four Oral Prototype Extended Release Formulations With BI 11634 in Healthy Male Volunteers

Healthy
GlaxoSmithKline

Completed

A Study To See If GSK256073A Can Block Niacin-Induced Flushing In Healthy Volunteers

Healthy Subjects | Dyslipidaemias

United States
Grünenthal GmbH

Completed

A Clinical Study in Healthy Adults Who Sometimes Take Drugs for Pleasure Which Aims to Evaluate Whether GRT0151Y is Likely to be Abused

Pain | Acute Pain

Canada
AstraZeneca

Completed

A Study to Estimate the Effect of AZD5718 on the Pharmacokinetics (What Does the Body Does to the Drug) of Rosuvastatin to Measure the Relative Bioavailability (the Extent to Which a Drug or Other Substance Becomes Available to the Body) of AZD5718 Oral Suspension vs AZD5718 Immediate Release Tablet

High Risk Coronary Artery Disease

United Kingdom
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of Baclofen Vs Naltrexon in Achieving & Maintaining Abstinence in Alcohol Dependence.

Alcohol Liver Disease

India
University of North Carolina, Chapel Hill
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Efficacy and Safety of High Dose Baclofen for Alcohol Dependence

Alcoholism

United States
Pfizer

Completed

Relative Bioavailability Study of a Modified-Release Formulation of PF-06865571 in Healthy Adult Participants

Healthy Participants

Belgium
Boehringer Ingelheim

Completed

Pramipexole Pilot Phase II Study in Children and Adolescents With Tourette Disorder According to DSM-IV Criteria

Tourette Syndrome

United States, Germany
Essentia Health

Terminated

Preventing Alcohol Withdrawal With Oral Baclofen (BACLOFEN III)

Alcoholism | Alcohol Withdrawal

United States
Sha'ar Menashe Mental Health Center
Ministry of Health, Israel

Completed

Baclofen as Add-On to Standard Treatment of Alcohol- Dependent Patients

Alcohol Dependence

Israel
St. Luke's Hospital, Ireland

Unknown

Combination Hormone Therapy Followed by Radiation Therapy in Treating Patients With Prostate Cancer

Prostate Cancer

Ireland, United Kingdom
University Medicine Greifswald

Completed

Effects of 500 mg Immediate Release and Extended Release Methylnaltrexone on Loperamide-induced Delay of the Oro-cecal and Whole-gut Transit Time in Healthy Subjects (LOP-MNTX-2009)

Intestinal Obstruction

Germany
Depomed

Completed

Study in Advanced Parkinson's Disease Patients With Predictable Motor Fluctuations

Parkinson's Disease | Motor Fluctuations

United States
Astellas Pharma Global Development, Inc.

Completed

A Phase I Study to Compare 3 Different Strengths of an Extended Release Formulation of ASP015K to an Immediate Release Formulation of ASP015K

Healthy Volunteers | Pharmacokinetics of ASP015K | Food Effect

United States
Boehringer Ingelheim

Completed

Increasing Dose Study of Pramipexole in Two-way Cross-over Comparison of ER Tablet Versus IR Tablet in Japanese Healthy Male Volunteers

Healthy
Eisai Inc.
Eisai Limited

Completed

Comparison of 23 mg Donepezil Sustained Release (SR) to 10 mg Donepezil Immediate Release (IR) in Patients With Moderate to Severe Alzheimer's Disease

Alzheimer's Disease

United States
International Partnership for Microbicides, Inc.
Gilead Sciences

Withdrawn

Reversing the Epidemic in Africa With Choices in HIV Prevention (REACH)

HIV-1-infection

South Africa
Astellas Pharma Europe B.V.

Completed

A Study to Compare the Actions in the Body of Healthy Subjects of Three Modified Release Formulations of YM178 Under Fasted and Fed Conditions With One Immediate Release Formulation of YM178 Under Fasted Conditions

Healthy Subjects | Pharmacokinetics of YM178

Netherlands
University Hospital, Lille
Groupement Interrégional de Recherche Clinique et d'Innovation; Région Nord-Pas...

Unknown

Phone-based Safety Monitoring of Baclofen Prescriptions for Alcohol Use Disorder (BACLOPHONE)

Alcohol Use Disorder

France
Trevena Inc.

Completed

A Safety, Tolerability, PD and PK Study in Healthy Adults

Healthy

United States
GlaxoSmithKline

Completed

A Phase I/II Clinical Study of SK&F-105517-D in Japanese Patients With Chronic Heart Failure

Heart Failure, Congestive

Japan
Tong Lee

Completed

Open-label, Normal Healthy Volunteer Clinical Trial of a Novel Ondansetron Formulation

Healthy

United States
Sheba Medical Center

Completed

The Effect of Methylphenidate Treatment in Familial Attention Deficit/Hyperactivity Disorder (ADHD)

ADHD Predominantly Inattentive Type | Attention Deficit/Hyperactivity Disorder Combined Type | ADHD Predominantly Hyperactivity Type | ADHD-not Other Specified

Israel
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Characterization of Intramuscular Injections of Risperidone 4 Week Long-acting Injectable (LAI) Formulation in the Buttock of Patients With Schizophrenia

Psychotic Disorders | Schizophrenia

United States
Boehringer Ingelheim

Completed

The SUSTAIN Study Compares the Effects of Sustained and Immediate-release Pramipexole on the noctUrnal Symptoms of paTients With Advanced ParkInsoN's Disease Who Also Take L-Dopa

Parkinson Disease

China
Ocera Therapeutics, Inc.

Completed

OCR002-SP103 - Oral Immediate Release Study

Cirrhosis

United States
Janssen Korea, Ltd., Korea

Completed

A Study Comparing the Effectiveness and Safety of Extended Release (ER) Tramadol Hydrochloride (HCl)/Acetaminophen With Immediate Release (IR) Tramadol HCl/Acetaminophen in Participants With Moderate to Severe Postoperative Pain

Pain, Postoperative
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of 2 Fixed Dose Combination Tablets of Canagliflozin and Metformin Immediate Release (IR) With Respect to the Individual Components of Canagliflozin and Metformin IR Tablets in Healthy Volunteers

Healthy

United States
Alza Corporation, DE, USA

Completed

A Study on Efficacy (Effectiveness), Safety, and Impact on Quality of Life Measures of Dilaudid CR (Controlled Release);, Hydromorphone HCl in Patients With Chronic Low Back Pain

Low Back Pain
Impax Laboratories, LLC

Completed

Comparison of IPX054, IR Carbidopa-Levodopa, and CR Carbidopa-Levodopa in Subjects With Parkinson's Disease

Idiopathic Parkinson's Disease

United States
Transdermal Therapeutics, Inc.
Albert Einstein College of Medicine; Montefiore Medical Center

Unknown

The Analgesic Activity of a Topical Formulation in Patients With Osteoarthritis of the Hands

Osteoarthritis of the Hands
ViiV Healthcare

Completed

A Study to Assess the Food Effect and the Relative Bioavailability of the Cabotegravir (CAB) Pediatric Dispersible Tablet (DT) Formulation

HIV Infections

United States
Boehringer Ingelheim

Completed

Switching Nevirapine Immediate Release( IR) Based Regimen to Nevirapine Extended Release (XR) Based Regimen in Human Immunodeficiency Virus One (HIV-1) Infected Patients

HIV Infections

United States, France, Germany, United Kingdom
Pfizer
Bristol-Myers Squibb

Completed

Bioavailability Study Comparing Modified Release To Immediate Release Apixaban Tablets In Healthy Volunteers

Thrombosis

United States
Bayer

Completed

Efficacy and Safety of CIPRO XR Versus CIPRO IR in Patients With Complicated Urinary Tract Infections (EMERON)

Urinary Tract Infection

Italy
Assiut University

Unknown

The Effect Of DAAs on miRNA-122 And Insulin Resistance In Chronic HCV Patients

Chronic Hepatitis c
Boehringer Ingelheim

Completed

VERxVE Study on Efficacy and Safety of Nevirapine XR in Comparison to Nevirapine IR With Truvada in Naive HIV+ Patients

HIV Infections

United States, Argentina, Australia, Belgium, Botswana, Canada, France, Germany, Ireland, Italy, Mexico, Netherlands, Poland, Portugal, Puerto Rico, Romania, Russian Federation, South Africa, Spain, Switzerland, United Kingdom
Children's Hospital Medical Center, Cincinnati
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug Challenge

Fragile X Syndrome

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Radiation Therapy, Androgen Suppression, and Docetaxel in Treating Patients With High-Risk Prostate Cancer Who Have Undergone Radical Prostatectomy

Prostate Cancer

United States, Canada

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