Search clinical trials for: BioChaperone PDGF-BB

Total 847 results

Virchow Group
Adocia

Completed

Comparative Study of 3 Dose Regimens of BioChaperone to Becaplermin Gel for the Treatment of Diabetic Foot Ulcer

Diabetic Foot Ulcers

India
Adocia
Virchow Group

Completed

A Phase 3 Clinical Trial to Assess the Effectiveness of BioChaperone PDGF-BB In the Treatment of Chronic Diabetic Foot Ulcer

Diabetic Foot Ulcer

India
University of Alabama at Birmingham

Active, not recruiting

Release Kinetics in PRF Versus GEM21S With and Without Bone Substitutes: An In Vitro Analysis

Bone Loss

United States
Adocia

Completed

A Clinical Trial Investigating the Intra-subject Variability of Pharmacokinetics and Glucodynamics of BioChaperone Insulin Lispro U-100 Product and U-200 Product in Healthy Volunteers

Healthy

Germany
Newron Sweden AB
Quintiles, Inc.; Medtronic

Completed

A Safety and Tolerability Study of Intracerebroventricular Administration of sNN0031 to Patients With Parkinson's Disease

Parkinson's Disease

Sweden
Adocia

Completed

A Double-blinded, Randomised, Four-period Crossover Euglycemic Clamp Trial Investigating the Dose-response and Dose-exposure Relationship of BioChaperone Insulin Lispro in Three Different Doses in Subjects With Type 1 Diabetes

Diabetes Mellitus Type 1

Germany
University of Pennsylvania
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Preliminary Testing of New Treatment for Chronic Leg Wounds

Varicose Ulcer

United States
Adocia
Eli Lilly and Company

Completed

An Euglycemic Clamp Trial to Evaluate Pharmacokinetics of Single Doses of BioChaperone Insulin Lispro in Healthy Japanese Subjects

Healthy

Germany
Ophthotech Corporation

Terminated

Phase 2A Open Label Safety Study of Fovista® (Anti-PDGF BB) Regimen Administered in Combination With Anti-VEGF Therapy to Study Sub-Retinal Fibrosis in Neovascular AMD

Age-related Macular Degeneration

United States
Adocia

Completed

A Trial to Investigate the Dose-linearity of BioChaperone® Combo 75/25 and the Safety at Three Different Doses in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

Germany
Centre Hospitalier Universitaire de Nice

Recruiting

sFlt-1/PlGF Ratio: Impact on the Management of Patients With Suspected Pre-eclampsia (PROSPE)

Pre-Eclampsia

France
Assistance Publique - Hôpitaux de Paris
INSERM CESP1018

Completed

Preeclampsia Ratio (sFlt-1/PlGF) (PRECOG)

Preeclampsia

France
Ain Shams University

Completed

Socket Augmentation Using Platelet Concentrates, Atorvastatin Gel or Combination

Alveolar Socket Preservations
Universidad de Granada
BTI Biotechnology Institute

Active, not recruiting

Plasma Rich in Growth Factors in Post-extraction Sockets

Dental Implants | Tooth Extraction

Spain
Adocia

Completed

A Trial to Investigate the Safety and the Pharmacokinetic, Pharmacodynamic Characteristics of Two BioChaperone® Glucagon Formulations Compared to Marketed GlucaGen® in Subjects With T1DM

Type 1 Diabetes Mellitus

Germany
Adocia
Eli Lilly and Company

Completed

To Investigate the Efficacy and Safety of Individualized Doses of BioChaperone Insulin Lispro in Comparison to Humalog® U-100 in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Germany
Bliss Biopharmaceutical (Hangzhou) Co., Ltd

Active, not recruiting

A First-in-human Study of Multiple Doses of BB-1701 in Subjects With Locally Advanced/Metastatic HER2 Expressing Solid Tumors

Locally Advanced/Metastatic HER2 Positive Solid Tumors

China, United States
Price Vision Group

Not yet recruiting

Plasma Rich in Growth Factors in Corneal Endothelial Transplantation

Corneal Edema | Fuchs' Endothelial Dystrophy

United States
Adocia

Completed

Blood Glucose Control With BioChaperone Insulin Lispro Compared to Insulin Lispro (Humalog®) After Ingestion of a Standardized Meal

Diabetes Mellitus Type 1

Germany
Adocia
Eli Lilly and Company

Completed

A Trial Investigating the Continuous Subcutaneous Insulin Infusion of a Liquid Formulation of BioChaperone Insulin Lispro in Comparison to Humalog®

Type 1 Diabetes Mellitus

Germany
Adocia
Eli Lilly and Company

Completed

A Trial to Investigate the Efficacy, Pharmacokinetics, Safety and Tolerability of BioChaperone Insulin Lispro in Comparison to Humalog® U-100 in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Germany
Center of Implantology, Oral and Maxillofacial...

Active, not recruiting

Reconstructive Therapy of Peri-implantitis With PDGF-BB (Gem-21)

Peri-Implantitis

Spain
Adocia

Completed

A Double-blinded, Randomised, Two -Period Crossover Euglycemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Insulin Lispro and Insulin Lispro (Humalog®) in Subjects With Type 1 Diabetes

Diabetes Mellitus Type 1

Germany
Adocia

Completed

A Trial to Assess the Efficacy and Safety of BioChaperone Combo and Humalog Mix 25 in Subjects With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Germany
Bliss Biopharmaceutical (Hangzhou) Co., Ltd

Recruiting

A First-in-human of Multiplle Doses of BB-1709 in Subjects With Locally Advanced/Metastatic Solid Tumors

Solid Tumor

China
Blue Blood Biotech Corp.

Completed

BB-101 for Treatment of Diabetic Lower Leg and Foot Ulcers

Diabetic Foot Ulcer

Taiwan
Benitec BioPharma Ltd

Completed

A Study of BB-401 in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

Australia, Russian Federation
Democritus University of Thrace

Completed

Assessment of Near Vision Capacity in Different Light Intensities

Presbyopia

Greece
Meir Medical Center

Completed

Plasma Rich in Growth Factors (PRGF) Treatment for Muscle Tear

Muscle Tear

Israel
Adocia

Completed

A Trial to Compare Post Prandial Blood Glucose Control of BioChaperone® Combo With Humalog® Mix25 and With Simultaneous Injections of Humalog® and Lantus® in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

Germany
Adocia

Completed

Postprandial Blood Glucose Control With BioChaperone® Combo and Insulin Lispro (Humalog®) Mix 25 in People With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Germany
University of California, Los Angeles
Yale University; University of Nebraska

Completed

Measuring and Monitoring Adherence to ART With Pill Ingestible Sensor System

HIV/AIDS | Medication Adherence

United States
Clinica Oftalmologica Paredes

Completed

Autologous Platelet-rich Plasma as a Treatment for Macular Holes

Macular Holes | Macular Hole of Left Eye (Disorder) | Macular Hole of Right Eye (Disorder)

Colombia
Benitec Biopharma, Inc.

Recruiting

A Study to Evaluate the Safety and Clinical Activity of Intramuscular Doses of BB-301 Administered to Subjects With Oculopharyngeal Muscular Dystrophy With Dysphagia

Oculopharyngeal Muscular Dystrophy

United States
Fundación Eduardo Anitua

Recruiting

Randomized Clinical Trial, Conventional Treatment-controlled, Studying the Efficacy of Plasma Rich in Growth Factor (PRGF®) in Alveolar Ridge Preservation After Simple Exodontia in the Anterior Region of Maxilla.

Dental Implantation

Spain
Yuzuncu Yıl University
VSY Biotechnology

Recruiting

Evaluation of the Long-term Efficacy and Safety of Monofocal Plate Haptic Intraocular Lens

Cataract | Lens Implantation, Intraocular

Turkey
Corcept Therapeutics

Active, not recruiting

A Sub Study of the Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant in Patients With Presumed Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis (NASH)

United States
Fetal Medicine Research Center, Spain

Unknown

Role of Placental Growth Factor (PlGF) in the Management of Non-Severe Preeclampsia (MAP)

Pregnancy; Pre-eclampsia, Mild

Spain
Centre Hospitalier Metropole Savoie

Completed

Evaluation of the Serum Markers sFLt1 and PlGF for the Prediction of the Complications of the Placental Vascular Pathologies in the 3rd Quarter of the Pregnancy. (PRECOPE)

Eclampsia | Pre-Eclampsia | HELLP Syndrome | Fetal Death | Placental Abruption | Fetal Growth Retardation, Antenatal

France
University of Roma La Sapienza
Universidade da Coruña; NYU College of Dentistry

Unknown

Plasma Rich in Growth Factors for Treatment of Medication Related Osteonecrosis of the Jaw

Osteonecrosis Due to Drugs, Jaw
The University of Texas Health Science Center,...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Combination Probiotic: BB-12 With LGG (Different Doses) in Treating Children With Autism Spectrum Disorder

Autism Spectrum Disorder | Gastrointestinal Symptoms

United States
Adocia

Completed

A Trial to Compare BioChaperone Insulin Lispro Formulations With US Approved Humalog® and With EU Approved Humalog® in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes

Germany
Adocia

Completed

A Trial to Compare the Pharmacodynamic and Pharmacokinetic Properties of Biochaperone® Combo With Humalog® Mix25 and With Simultaneous Injections of Humalog® and Lantus® in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

Germany
Irish Centre for Fetal and Neonatal Translational...
University College Cork; National Maternity Hospital, Ireland; Coombe Women and... and other collaborators

Completed

Placental Growth Factor Assessment of Women With Suspected Pre-eclampsia (PARROT)

Pregnancy Complications | Pregnancy, High Risk | Pre-eclampsia

Ireland
Queen Mary University of London

Recruiting

Autologous Platelet Concentrate (APC) in Intrabony Defects

Periodontal Diseases

United Kingdom
Women and Infants Hospital of Rhode Island

Completed

A Pilot Study Assessing the Feasibility and Effectiveness of a Breastfeeding Educational Video on Breastfeeding Rates

Breastfeeding, Exclusive

United States
Biobeat Technologies Ltd.
Sheba Medical Center

Completed

Early Identification of Clinical Deterioration Using a Wearable Monitoring Device

Hemodynamic Instability | Clinical Deterioration

Israel
Clinica Universidad de Navarra, Universidad de...

Unknown

Treatment of Osteoarthritis by Intra-articular Injection of Bone Marrow Mesenchymal Stem Cells With Platelet Rich Plasma (CMM-PRGF/ART)

Knee Osteoarthritis

Spain
Fuzhou General Hospital

Unknown

The Plasma Diafiltration Therapy of Hepatic Failure

Hepatic Failure | Plasma Exchange

China
Biotechnology Institute IMASD

Unknown

Plasma Rich in Growth Factors (PRGF-Endoret)in the Treatment of Androgenetic Alopecia

Androgenetic Alopecia

Spain

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