Search clinical trials for: Biological: TCR-T

Total 8498 results

Federal Research Institute of Pediatric Hematology...

Completed

TCR Alpha/Beta Depletion for HSCT From Haploidentical and Unrelated Donors in the Treatment of PID

Primary Immune Deficiency Disorder | Hematopoietic Stem Cell Transplantation

Russian Federation
Lion TCR Pte. Ltd.
Third Affiliated Hospital, Sun Yat-Sen University; Agency for Science, Technology...

Unknown

A Study of TCR-Redirected T Cell Infusion in Subject With Recurrent HBV-related HCC Post Liver Transplantation

Recurrent Hepatocellular Carcinoma

China
Beijing 302 Hospital

Active, not recruiting

Autologous T-cells Transfected With mRNA Encoding HBV-TCR T Cell Therapy in Combination With NUC for Chronic Hepatitis B

Chronic Hepatitis B

China
Sun Yat-sen University

Unknown

Phase I Trial of LMP2 Antigen-specific TCR T-cell Therapy for Recurrent and Metastatic NPC Patients

Nasopharyngeal Carcinoma

China
Fudan University
Guangzhou Bioresette Biomedical Technology Co., Ltd.; Chaosu Hu，Principal Investigator...

Recruiting

Clinical Study on the EBV CAR-T /TCR-T Cells in the Treatment of Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Second Affiliated Hospital of Guangzhou Medical...
Tcell Immune (Guangzhou) Science and Technology Ltd.

Recruiting

TCR-T Cell Immunotherapy of Lung Cancer and Other Solid Tumors

Nonsmall Cell Lung Cancer | Solid Tumor, Adult

China
Beijing 302 Hospital
Lion TCR Pte. Ltd.

Recruiting

TCR-Redirected T Cells Therapy in Patient With HBV Related HCC

Hepatocellular Carcinoma

China
Hebei Yanda Ludaopei Hospital
China Immunotech (Beijing) Biotechnology Co., Ltd.

Completed

CMV-TCR-T Cells for CM Virus Infection After HSCT

CMV Infection or Reactivation After Allogenic HSCT

China
Lion TCR Pte. Ltd.
First Affiliated Hospital, Sun Yat-Sen University; Sun Yat-Sen Memorial Hospital...

Completed

A Study of TCR-Redirected T Cell Infusion to Prevent Hepatocellular Carcinoma Recurrence Post Liver Transplantation

Hepatocellular Carcinoma

China
Chinese PLA General Hospital

Recruiting

Clinical Study of EBV-TCR-T Cells for EBV Infection After Allogenic HSCT

EBV Infection After Allogenic HSCT

China
Chinese PLA General Hospital

Recruiting

CMV-TCR-T Cells for CMV Infection After Allogenic HSCT

CMV Infection After Allogenic HSCT

China
Hebei Yanda Ludaopei Hospital
China Immunotech (Beijing) Biotechnology Co., Ltd.

Completed

EBV-TCR-T Cells for EB Virus Infection After HSCT

EBV Emia and EBV Positive PTLD After Allogenic HSCT

China
Timmune Biotech Inc.
The Second Affiliated Hospital of Hainan Medical University; Hainan Cancer...

Unknown

Treatment of Malignant Melanoma With GPA-TriMAR-T Cell Therapy

Malignant Melanoma

China
Chinese PLA General Hospital

Recruiting

Clinical Study of EBV-TCR-T Cells for EBV-associated Hemophagocytic Lymphohistiocytosis or EBV Infection

EBV Infection | EBV-associated Hemophagocytic Lymphohistiocytosis

China
Zhongda Hospital

Recruiting

Clinical Study of TCR-like CAR-T Cell Targeted MSLN in the Treatment of Ovarian Cancer

Safety and Efficacy of TCR-like CAR-T

China
Xiao-Jun Huang

Recruiting

CMV-TCR-T Cells for Refractory CMV Infection After HSCT

Allogeneic Hematopoietic Stem Cell Transplantation | CMV Infection

China
Shenzhen University General Hospital

Recruiting

Study of NY-ESO-1 TCR-T in Advanced Soft Tissue Sarcoma

Advanced Soft-tissue Sarcoma

China
National Cancer Institute (NCI)

Terminated

Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions

Neoplasms, Squamous Cell | Squamous Lntraepithelial Lesions of Vulva | Vulvar HSIL

United States
Cell Medica Ltd
University College, London; Cell Therapy Catapult

Completed

WT1 TCR Gene Therapy for Leukaemia: A Phase I/II Safety and Toxicity Study

Acute Myeloid Leukaemia | Chronic Myeloid Leukaemia

United Kingdom
Lion TCR Pte. Ltd.

Recruiting

Redirected HBV-Specific T Cells in Patients With HBV-related HCC (SAFE-T-HBV) (SAFE-T-HBV)

Hepatocellular Carcinoma

Singapore
Guangzhou 8th People's Hospital
Sun Yat-sen University

Completed

Effect of Chidamide Combined With CAT-T or TCR-T Cell Therapy on HIV-1 Latent Reservoir

HIV/AIDS

China
Xinqiao Hospital of Chongqing
TCRCure Biopharma Ltd.

Unknown

HPV-E6-Specific Anti-PD1 TCR-T Cells in the Treatment of HPV-Positive NHSCC or Cervical Cancer

Cervical Cancer | Head and Neck Squamous Cell Carcinoma

China
Christian Hinrichs
National Cancer Institute (NCI)

Not yet recruiting

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

Cervical Cancer | HPV-Related Malignancy | Vulvar Cancer | Anal Cancer | Oropharynx Cancer | Vaginal Cancer | HPV-Related Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Penile Cancer | HPV-Associated Cervical Carcinoma | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma | HPV-Related... and other conditions

United States
The Netherlands Cancer Institute

Unknown

Study With T-cel Receptor Gene Therapy in Metastatic Melanoma (TCR)

Stage IV Skin Melanoma | Eye; Melanoma

Netherlands
Ruijin Hospital
Shanghai Essight Bio Co.,Ltd

Recruiting

TCR-T Cells in the Treatment of Advanced Pancreatic Cancer (GB3010-02)

Pancreatic Cancer

China
Wuhan Union Hospital, China

Not yet recruiting

CD19/BCMA HLA-independent TCR-T Cell Therapy for Refractory/Moderate-to-severe Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
University College, London

Suspended

Study of Adoptive Immunotherapy With Donor-derived CMV-specific T Cells for Recipients of Allo-HSCT (CMV_TCR-001)

CMV Infection | Haematological Malignancies

United Kingdom
Tianjin Medical University Cancer Institute and...

Unknown

Clinical Safety and Preliminary Efficacy of MAGE-A4 TCR Gene-Modified T Cells to Treat Malignant Tumors

Malignant Solid Tumors

China
Mariella Enoc

Completed

Trial to Assess the Efficacy of a TCR Alfa Beta Depleted Graft in Pediatric Affected by ALL or AML and Receiving an HSCT

Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Non-Hodgkin Lymphoma | Leukemia Acute Myeloid - AML

Italy
Xiaoshun He
Lion TCR Pte. Ltd.

Unknown

TCR-Redirected T Cell Treatment in Patients With Recurrent HBV-related Hepatocellular Carcinoma Post Liver Transplantation

Recurrent Hepatocellular Carcinoma

China
University of Pennsylvania
Adaptimmune

Completed

Redirected High Affinity Gag-Specific Autologous T Cells for HIV Gene Therapy

HIV Infections

United States
Shenzhen BinDeBio Ltd.
Henan Provincial People's Hospital

Recruiting

Autologous CAR-T/TCR-T Cell Immunotherapy for Solid Malignancies

Glioma | Gastric Cancer | Hepatoma | Esophagus Cancer

China
T-knife GmbH

Terminated

A Phase 1/ 2, First-in-Human, Open-Label, Accelerated-Titration, Two-Part Clinical Trial of TK-8001 in Patients With HLA-A*02:01 Genotype and Advanced-Stage/ Metastatic MAGE-A1+ Solid Tumors (IMAG1NE)

Advanced Solid Tumors

Germany, Belgium, Spain, Netherlands, United Kingdom
Fudan University

Unknown

The Study of Targeted NY-ESO-1 T Cell Receptor (TCR) Genetic Modified Autologous T Cells Treatment of Advanced Solid Tumors

Advanced Malignant Solid Tumors

China
Sun Yat-sen University
Guangdong Xiangxue Precision Medical Technology Co., Ltd.

Recruiting

Phase II Study of TAEST16001 in Soft Tissue Sarcoma

Soft Tissue Sarcoma

China
University of California, San Francisco
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Individualized Study of Refeeding to Optimize iNpatient Gains (i-STRONG)

Atypical Anorexia Nervosa

United States
Second Affiliated Hospital, School of Medicine,...
TCRx Therapeutics Co.Ltd

Not yet recruiting

TCRx_T Cells for Advanced or Recurrent Gastric/Gastroesophageal Junction Cancer After Failure of First Chemotherapy

Gastric Cancer | Gastroesophageal-junction Cancer
Xinqiao Hospital of Chongqing
TCRCure Biopharma Ltd.

Recruiting

EBV-Specific Anti-PD1 TCR-T Cells in the Treatment of EBV-Positive NHSCC

Head and Neck Squamous Cell Carcinoma

China
Peking University
Shanghai Ming Ju Biotechnology Co., Ltd.

Recruiting

MAGE-A4-directed TCR-T in the Treatment Amongst Subjects With Advanced Solid Tumors

Advanced Solid Tumor

China
Pritikin ICR
Mission Health System, Asheville, NC; Trinity Health; Connecting Health Innovation and other collaborators

Recruiting

Multi-Center Study of Clinical and Inflammatory Outcomes in Intensive Cardiac Rehabilitation and Traditional Cardiac Rehabilitation Programs (CREDIBLE)

Cardiovascular Diseases

United States
University of Adelaide
University of Sydney; Salk Institute for Biological Studies

Recruiting

Calories or Time Restriction to Alter Biomarkers of Aging and Diabetes (OMIT)

Obesity

Australia
University Hospital Tuebingen

Completed

NGS Diagnostic in COVID-19 Hosts - Genetic Cause Relating to the Course of Disease Progression (COVID-19 NGS)

COVID-19

Germany
Alaunos Therapeutics

Recruiting

Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs

Gynecologic Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Cholangiocarcinoma | Adenocarcinoma of Lung | Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Ovary Neoplasm | Adenosquamous Cell Lung Cancer

United States
Cellular Biomedicine Group Ltd.
Peking University Cancer Hospital & Institute

Unknown

The Study of Surgery,Chemotherapy and Autologous T Cells-Based Immunotherapy for Advanced Gastric Cancer.

Gastric Cancer.
University Hospital, Montpellier

Recruiting

Collection of Biological Samples From Patients Treated With CAR-T Cells for Hematological Malignancies (CAR-T BANK)

Lymphoma and Acute Lymphoblastic Leukemia

France
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

TCR-T Cell Therapy on Advanced Pancreatic Cancer

Pancreatic Cancer

China
Christian Hinrichs

Recruiting

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

Cervical Cancer | HPV-Related Malignancy | Metastatic Cancer | Anal Cancer | Oropharynx Cancer | Vaginal Cancer | HPV-Related Carcinoma | HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Penile Cancer | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma | HPV-Related... and other conditions

United States
Immune Cell, Inc.
Weifang People's Hospital

Recruiting

CD30 Targeted CAR-T in Treating CD30-Expressing Lymphomas

Hodgkin Lymphoma | Anaplastic Large Cell Lymphoma

China
Corregene Biotechnology Co., Ltd

Not yet recruiting

CRTE7A2-01 TCR-T Cells for HPV-16 Positive Advanced Cancers

Cervical Cancer | Anal Cancer | Head and Neck Cancers | Other Solid Tumors
University Hospital, Lille

Completed

Biological Meshes in Infected Fields: a Randomized Controlled Trial (SIMBIOSE)

Ventral Hernia

France

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