Search clinical trials for: buprenorphine and naloxone

Total 272142 results

University of California, San Francisco

Not yet recruiting

Naloxone for Opioid Associated Out of Hospital Cardiac Arrest (NOPACA)

Heart Arrest, Out-Of-Hospital | Naloxone | Opioid Overdose

United States
University of California, San Francisco

Terminated

Efficacy of Nalbuphine and Naloxone Administered as Nose Sprays in the Treatment of Orofacial Pain

Temporomandibular Joint Dysfunction Syndrome | Burning Mouth Syndrome

United States
Mitovie Pharma Ltd

Unknown

Naloxone Nasal Spray Pharmacokinetic Study

Opioid Overdose

Jordan
Taiwan Mundipharma Pharmaceuticals Ltd.
Chang Gung Memorial Hospital; Taipei Medical University Shuang Ho Hospital; Changhua...

Completed

Safety and Effectiveness of Transdermal Buprenorphine in Cancer Pain (SOOTHE)

Cancer

Taiwan
St. Louis University

Completed

Buprenorphine Dose Adjustments and Gestational Age

Neonatal Abstinence Syndrome
Purdue Pharma LP

Completed

Safety of Buprenorphine Transdermal Systems in Subjects With Chronic Nonmalignant Pain - a 28-week Extension Study

Chronic Nonmalignant Pain

United States
Purdue Pharma LP

Completed

Examine Plasma Concentrations of Buprenorphine Following Reapplication of Buprenorphine Transdermal System (BTDS) After Variable Application Site Rest Periods

Healthy

United States
Mundipharma Research GmbH & Co KG

Completed

Oxycodone/Naloxone Prolonged Release (OXN PR) Compared to Placebo to Demonstrate Improvement in Symptoms of Restless Legs Syndrome (RLS) in Subjects With Moderate to Severe Idiopathic RLS With Daytime Symptoms

Moderate to Severe Idiopathic RLS With Daytime Symptoms

Spain, Sweden, Germany
BioDelivery Sciences International

Completed

Evaluation of the Tolerability of Switching Subjects on Chronic ATC Opioid Therapy to Buprenorphine HCl Buccal Film

Pain

United States
NYU Langone Health
National Institute on Drug Abuse (NIDA)

Withdrawn

Assessing Optimal XR-Buprenorphine Initiation Points in Jail

Opioid Use Disorder

United States
PATH
London School of Hygiene and Tropical Medicine; Monash University; University... and other collaborators

Not yet recruiting

Assessing the Acceptability, Feasibility, Effectiveness and Cost-effectiveness of LADB

Opioid Dependence
BioDelivery Sciences International

Completed

An Open Label Study To Assess The Safety And Tolerability Of BEMA® Buprenorphine NX In Opioid Dependent Subjects

Opioid Dependence

United States
Mundipharma Pharmaceuticals Sdn. Bhd.

Completed

Efficacy and Safety of Buprenorphine Transdermal Patch in Non-cancer Pain of Moderate Intensity

Osteoarthritis | Rheumatoid Arthritis | Lower Back Pain | Joint Pain | Muscle Pain

Malaysia
Purdue Pharma LP

Terminated

Safety of Buprenorphine Transdermal Patch (BTDS) in Osteoarthritis Pain: a 52-Week Extension Phase

Osteoarthritis

United States
Purdue Pharma LP

Terminated

Safety of BTDS in Subjects With Low Back Pain: A 52-Week Extension Phase of BUP3015

Back Pain Lower Back Chronic

United States
Purdue Pharma LP

Completed

The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Osteoarthritis Pain.

Osteoarthritis

United States
University Hospital Inselspital, Berne

Completed

Early Postoperative Administration of Oxycodone +/- Naloxone and Duration of Epidural Analgesia

Epidural Analgesia | Radical Cystectomy | Postoperative Pain Management | Oral Oxycodone With/Without Naloxone | Return of the Bowel Function

Switzerland
Medical University of Vienna

Completed

Oral Oxycodone After Major Cardiac Surgery

Heart; Dysfunction Postoperative, Cardiac Surgery

Austria
Tanta University

Completed

Effect of Intrathecal Naloxone in the Incidence of Pruritis After C.S

Pruritis

Egypt
Washington University School of Medicine

Recruiting

Transdermal Patch for BupRenorphine Induction DurinG PrEgnancy (Patch BRIDGE) (Patch BRIDGE)

Pregnancy Complications | Pregnancy Related | Pregnancy, High Risk | Opioid Use Disorder | Buprenorphine Withdrawal

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Models of Screening, Brief Intervention With a Facilitated Referral to Treatment (SBIRT) for Opioid Patients in the Emergency Department

Opiate Addiction

United States
Institut National de la Santé Et de la Recherche...

Completed

Double Blind Randomized, Monocentric, Cross-over, Placebo-controlled Study to Evaluate the Effect of Morphine and Naloxone on Motivation (MBBAnalgesic) (MBBAnalgesic)

Healthy

France
Vanderbilt University Medical Center
National Institute on Drug Abuse (NIDA)

Completed

Reduced Opioid Analgesic Requirements Via Improved Endogenous Opioid Function

Chronic Pain

United States
University of Cincinnati
National Institute on Drug Abuse (NIDA)

Completed

A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses (TTIP-PRO)

Opioid-Related Disorders | Substance Abuse | Drug Overdose | Drug Abuse | Drug Addiction

United States
Mundipharma Research GmbH & Co KG

Completed

A Study to Demonstrate Improvement in Symptoms of Constipation in Subjects That Require Around-the-clock Opioid Pain Killer Therapy

Pain | Constipation

United Kingdom
Purdue Pharma LP

Completed

Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain

Low Back Pain

United States, Poland, Czech Republic, Italy
Mayo Clinic
National Cancer Institute (NCI)

Completed

Ruxolitinib Phosphate and Danazol in Treating Anemia in Patients With Myelofibrosis

Primary Myelofibrosis | Anemia | Secondary Myelofibrosis

United States
Women and Infants Hospital of Rhode Island
National Institute of General Medical Sciences (NIGMS)

Withdrawn

Randomized Control Trial of Buprenorphine vs. Morphine for the Treatment of Neonatal Opioid Withdrawal Syndrome (NOWS)

Neonatal Opioid Withdrawal Syndrome

United States
Titan Pharmaceuticals

Terminated

Study of Probuphine in Patients With Opioid Dependence (PRO-809)

Opioid Dependency

United States
National Institute on Drug Abuse (NIDA)
Alkermes, Inc.

Completed

Phase 1 Study to Evaluate RDC-0313 Coadministered With Buprenorphine to Opioid-Experienced Healthy Adults

Substance-Related Disorders

United States
Thomas Jefferson University

Completed

Buprenorphine for Treatment of Neonatal Abstinence Syndrome in Infants With In Utero Exposure to Benzodiazepines (MOPPlus)

Neonatal Abstinence Syndrome

United States
Johns Hopkins University

Recruiting

Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder (BIPOD-Out)

Opioid Use Disorder

United States
Indivior Inc.

Completed

Evaluation of Buprenorphine Extended-Release Subcutaneous Injection at Alternative Injection Locations

Opioid Use Disorder

United States
Albert Einstein College of Medicine
National Institute on Drug Abuse (NIDA); The City University of New York; Washington...

Completed

Pilot Test of a Community-based Buprenorphine Treatment Intervention

Opioid Dependence | Injection Drug Use

United States
Indivior Inc.

Completed

Multiple Dose Pharmacokinetics Depot Buprenorphine in Opioid-Dependent Subjects

Opioid Related Disorder

United States
Artoss Inc.

Recruiting

Rate of Bony Fusion Using NanoBone® Synthetic Bone Graft Versus Local Autologous Bone Graft. (BONE)

Degenerative Disc Disease | Spondylolisthesis

United States
Johann Wolfgang Goethe University Hospital

Completed

Evaluation of Fusion After ALIF With an Osteoinductive Material or With Homologus Bone

Fusion of Spine, Lumbar Region
University of California, Irvine

Recruiting

Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia

Hyperalgesia

United States
Purdue Pharma LP

Completed

A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Mundipharma Research GmbH & Co KG

Completed

A Study to Demonstrate the Analgesic Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Addition to Pregabalin Compared to Pregabalin Alone in Opioid-naïve Subjects Treated With Pregabalin Suffering From Moderate to Severe Pain Due to Diabetic Polyneuropathy

Moderate to Severe Pain Due to Diabetic Polyneuropathy

Germany
University of California, San Diego
San Diego State University

Recruiting

"Bupe by the Book": A Tele-Buprenorphine Clinical Trial in Public Libraries With Unstably Housed Persons With Opioid Use Disorder (BBB)

Control Group | Telehealth at the Library

United States
Indivior Inc.

Completed

Study of a Novel Subcutaneous Depot Formulation of Buprenorphine

Opioid-use Disorder

United Kingdom
Purdue Pharma LP

Terminated

Safety of Buprenorphine Transdermal System (BTDS) in Subjects With Acute Postoperative Pain After Total Knee Replacement

Postoperative Pain

United States
Mundipharma Pte Ltd.
Mundipharma Korea Ltd; Mundipharma (Hong Kong) Ltd; Mundipharma Distribution...

Completed

Evaluation Of Efficacy And Safety Of Norspan In Moderate To Severe Pain Due To Osteoarthritis, Rheumatoid Arthritis, Joint/Muscle Pain

Osteoarthritis | Rheumatoid Arthritis | Lower Back Pain | Joint Pain | Muscle Pain

Hong Kong, Korea, Republic of, Philippines
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Recruiting

Assessing a Clinically-meaningful Opioid Withdrawal Phenotype

Opioid Use Disorder | Opioid Withdrawal | Opioid Craving

United States
Ullevaal University Hospital
University of Oslo

Terminated

Reversal of Ketamine Pharmacodynamic Effects With Naloxone

Pain

Norway
NYU Langone Health
Harvard Medical School (HMS and HSDM); National Institute on Drug Abuse (NIDA) and other collaborators

Recruiting

Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)

Opioid Use Disorder (OUD)

United States
Mundipharma Korea Ltd

Completed

A Study to Evaluate Efficacy and Safety of Oxycodone/Naloxone Compared to OxyContin in Korean Cancer Patients (TOP)

Cancer

Korea, Republic of
Mundipharma Oy

Completed

OXN PR Compared to OXY PR in Subjects With Postoperative Pain After Knee Arthroplasty (OXN4505)

Post Operative Pain

Finland
Centre for Addiction and Mental Health
Academic Health Science Centres

Completed

Feasibility Study of Oral Naloxone for Treatment of Methadone-induced Constipation

Constipation

Canada

Search clinical trials for: buprenorphine and naloxone

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in China

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations