Search clinical trials for: CHS-006 (anti-TIGIT)

Total 1526 results

Coherus Biosciences, Inc.
Shanghai Junshi Bioscience Co., Ltd.; Medpace, Inc.

Active, not recruiting

Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors

Hepatocellular Carcinoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor

United States
University of Pennsylvania

Terminated

Penn Microbiome Therapy (PMT) for Severe-Clostridium Difficile Infection (CDI)

Severe Clostridium Difficile Infection | Severe-Complicated/Fulminant Clostridium Difficile Infection

United States
Shanghai Huaota Biopharmaceutical Co., Ltd.

Recruiting

A Study Evaluating the Safety and Efficacy of HB0036 in Subjects With Advanced Solid Tumors

NSCLC | Advanced Solid Tumor

United States, China
Alain Algazi
Genentech, Inc.

Recruiting

Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck

Carcinoma | Cancer | Head and Neck Cancer | Squamous Cell Carcinoma

United States
CAMP4 Therapeutics Corporation

Recruiting

Study of CMP-CPS-001 in Healthy Volunteers

Healthy Volunteers

Australia
Cerenis Therapeutics, SA
South Australian Health and Medical Research Institute

Completed

CER-001 Atherosclerosis Regression ACS Trial (CARAT)

Acute Coronary Syndromes

United States, Australia, Netherlands, Hungary
ImmunoFrontier, Inc.

Completed

Safety Study of a Recombinant Protein Vaccine to Treat Esophageal Cancer

Esophageal Cancer

Japan
Fudan University

Withdrawn

GP Chemotherapy in Combination With Tislelizumab and Ociperlimab as First-line Treatment in Advanced BTC

Intrahepatic Cholangiocarcinoma

China
National Institute of Allergy and Infectious Diseases...

Completed

Immune Response to an HIV DNA Plasmid Vaccine Prime Followed by Adenovirus Boost in HIV-uninfected Individuals

HIV Infections

United States
Cerenis Therapeutics, SA

Terminated

CER-001 Therapy as a Novel Approach to Treat Genetic Orphan Diseases (TANGO)

Familial Hypoalphalipoproteinemia

France, United States, Belgium, Canada, Israel, Italy, Netherlands
University of Ulm

Completed

Concentration of Ertapenem in Colorectal Tissue

Rectal Neoplasms | Colonic Neoplasms | Diverticulosis, Colonic

Germany
Shanghai Henlius Biotech

Recruiting

A Study Evaluating the Safety, Tolerability, Pharmacokinetic and Efficacy of HLX301(TIGIT×PDL1 Bispecific) in Locally Advanced/Metastatic Solid Tumors or Lymphoma (HLX301)

Lymphoma | Advanced Tumors | Metastatic Tumors

China
Merit E. Cudkowicz, MD
Massachusetts General Hospital

Active, not recruiting

HEALEY ALS Platform Trial - Master Protocol

Amyotrophic Lateral Sclerosis

United States
OncoMed Pharmaceuticals, Inc.

Terminated

A Study of OMP-313M32 in Subjects With Locally Advanced or Metastatic Solid Tumors

Metastatic Cancer | Locally Advanced Cancer

United States
Paion UK Ltd.
Premier Research Group plc

Completed

Multiple Dose Safety and Efficacy Study Evaluating CNS 7056 Versus Midazolam in Patients Undergoing Colonoscopy

Sedation

United States
Coherus Biosciences, Inc.

Completed

Comparison of CHS-1420 Versus Humira in Subjects With Chronic Plaque Psoriasis (PsOsim)

Plaque Psoriasis

United States, Canada, Bulgaria, Chile, Croatia, Estonia, Georgia, Israel, Italy, Latvia, Moldova, Republic of, Poland, Russian Federation, Slovakia, South Africa, Ukraine
University of Southern California
National Cancer Institute (NCI)

Terminated

CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma

Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm

United States
Omico
Hoffmann-La Roche; The George Institute for Global Health, Australia

Recruiting

Tiragolumab and Atezolizumab in Advanced Pan-cancer Patients (MoST-TAP)

Solid Tumor, Adult

Australia
Huabo Biopharm Co., Ltd.
First Affiliated Hospital Bengbu Medical College

Recruiting

A Study of HB0030 Injection in Patients With Advanced Solid Tumors

Advanced Solid Tumor

China
Bio-Thera Solutions

Terminated

Assessment of Safety and Preliminary Efficacy With BAT6021 in Solid Tumor Patients

Advanced Solid Tumor

Australia
Hoffmann-La Roche

Completed

A Phase 1 Clinical Study in Healthy Volunteers to Investigate the Drug-drug Interaction Between Multiple Doses of RO7033877 and Multiple Doses of Colistin Methanesulfonate Sodium (CMS)

Healthy Volunteer

Netherlands
University Hospital of Ferrara

Completed

Periodontal Wound Healing With CHX and Hyaluronic Acid (CHX+HA+ADS)

Wound Healing | Surgical Flaps | Gingiva

Italy
The University of Tennessee, Knoxville

Completed

Carbohydrate-Protein Supplementation During Endurance Running

Supplementation During Endurance Performance

United States
Huahui Health

Completed

A Study to Evaluate the Antiviral Activity and Safety of HH-003 Injection in Subjects With HBeAg-Negative Chronic Hepatitis B Treated With Nucleos(t)Ide Reverse Transcriptase Inhibitors

Chronic Hepatitis B

China
Rznomics, Inc.

Recruiting

A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 With Valganciclovir (VGCV) in Subjects With Hepatocellular Carcinoma

Hepatocellular Carcinoma

Korea, Republic of
Medline Industries

Completed

Evaluation 2% Chlorhexidine Gluconate

Skin Coverage
Clearside Biomedical, Inc.

Completed

Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis (DOGWOOD)

Uveitis, Anterior | Panuveitis | Uveitis | Macular Edema | Uveitis, Posterior | Uveitis, Intermediate

United States
Gilead Sciences

Completed

SOF (Sovaldi®) +RBV for 16 or 24 Weeks and SOF+RBV+Peg-IFN for 12 Weeks in Adults With Genotype 2 or 3 Chronic HCV Infection

Hepatitis C

United States, Canada, United Kingdom, Australia, New Zealand
University Psychiatric Clinics Basel
University of Basel

Not yet recruiting

ID-ClimAct. Influence of Social Motives of Clients and Staff on the Social Climate of Secure Settings (ID-ClimAct)

Interpersonal Relations | Social Dominance | Social Environment | Correctional Institutions | Rehabilitation of Criminals

Switzerland
National Vaccine and Serum Institute, China
China National Biotec Group Company Limited; Lanzhou Institute of Biological... and other collaborators

Recruiting

Clinical Trial on Sequential Immunization of Recombinant COVID-19 Vaccine (CHO Cells,NVSI-06-08) and Inactivated COVID-19 Vaccine (Vero Cells) in Population Aged 18 Years and Above

Coronavirus Infections | COVID-19 Pneumonia

United Arab Emirates
Aptevo Therapeutics

Completed

Phase 1/1b Study of TRU-016 in Patients With Previously Treated CLL or Select Subtypes of Non-Hodgkin's Lymphoma

Chronic Lymphocytic Leukemia (CLL) | Non-Hodgkin's Lymphoma (NHL)

United States
National Taiwan University Hospital
Min-Sheng General Hospital; Lotung Poh-Ai Hospital; Hualien Tzu Chi General Hospital and other collaborators

Recruiting

Chlorhexidine to Prevent Catheter-related Urinary Tract Infection

Urinary Tract Infections

Taiwan
University of Bern
Swiss Federal Institute of Technology

Completed

Efficacy of Taiji Training as a Program for Stress Prevention

Stress | Primary Prevention | Adult | Tai ji

Switzerland
Entos Pharmaceuticals Inc.
Canadian Institutes of Health Research (CIHR); Aegis Life, Inc.; Clinical Pharma... and other collaborators

Completed

A Clinical Trial of a Prophylactic Plasmid DNA Vaccine for COVID-19 [Covigenix VAX-001] in Adults

SARS-CoV-2

Burkina Faso, Canada, Senegal, South Africa
Chiesi Farmaceutici S.p.A.

Completed

A Phase II, 5-way Cross-over Study to Evaluate the Pharmacodynamics of "Nexthaler" Dry Powder Inhaler in COPD Patients (NEXThaler)

COPD

United Kingdom
Julia Brown
Pfizer; Arthritis Research UK

Completed

TIght COntrol of Psoriatic Arthritis (TICOPA)

Psoriatic Arthritis

United Kingdom
Oblato, Inc.

Withdrawn

Investigation of Oral OKN-007 in Recurrent High-grade Glioma Participants

Glioblastoma | Astrocytoma | Oligodendroglioma
DermaGen AB

Completed

A Randomized, Double-blinded Placebo-controlled Study to Investigate Antimicrobial Efficacy and Safety Following Topical Application of DPK-060

Atopic Dermatitis

Sweden
Johns Hopkins Bloomberg School of Public Health
International Centre for Diarrhoeal Disease Research, Bangladesh; Government... and other collaborators

Completed

Impact of Umbilical Cord Cleansing With 4.0% Chlorhexidine on Neonatal Mortality (CHX)

Infection | Omphalitis

Bangladesh
Huahui Health

Terminated

A Study to Evaluate the Antiviral Activity and Safety of HH-003 Injection in Subjects With Chronic Hepatitis B and Hepatitis D Co-infection

Chronic Hepatitis B and Hepatitis D Co-infection

China
CareFusion

Completed

Components of Chlorhexidine Gluconate Dressing

Healthy

United States
University Hospital, Grenoble

Completed

Impact of Tegaderm HP and CHG in Major Catheter Related Infections and Dressing Detachment (DRESSING2)

Catheter-Related Infections

France
Florida State University
Wayne State University; Children's Hospital Los Angeles; Hunter College of City...

Completed

Adherence Interventions for HIV Youth Via Text & Cell Phone - Sequential Multiple Assignment Randomized Trial (SMART) (SMART)

HIV Infections

United States
RH Nanopharmaceuticals
Center for Bioequivalence Studies and Clinical Research

Completed

Phase 1 Clinical Trial of RHN-001 in Healthy Adult Volunteers

Pharmacokinetics | Tolerability | Safety

Pakistan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride, Cisplatin, and Nab-Paclitaxel in Treating Patients With Advanced or Metastatic Biliary Cancers

Unresectable Extrahepatic Bile Duct Carcinoma | Unresectable Gallbladder Carcinoma | Stage IIIA Gallbladder Cancer AJCC v7 | Stage IIIB Gallbladder Cancer AJCC v7 | Stage IVA Gallbladder Cancer AJCC v7 | Stage IVB Gallbladder Cancer AJCC v7 | Stage III Intrahepatic Cholangiocarcinoma AJCC v7 | Stage... and other conditions

United States
Multiple Myeloma Research Consortium
Bristol-Myers Squibb; Memorial Sloan Kettering Cancer Center; Washington University... and other collaborators

Active, not recruiting

Immuno-Oncology Drugs Elotuzumab, Anti-LAG-3 and Anti-TIGIT

Multiple Myeloma | Relapsed Refractory Multiple Myeloma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases

Intrahepatic Cholangiocarcinoma | Gallbladder Carcinoma | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Metastatic Malignant Neoplasm in the Peritoneum | Distal Bile Duct Adenocarcinoma | Stage IV Distal Bile Duct Cancer AJCC v8 | Stage IV Intrahepatic Bile Duct Cancer AJCC v8 | Stage IVB Gallbladder...

United States
National Cancer Institute (NCI)
NRG Oncology

Terminated

Testing the Addition of an Anti-cancer Immune Therapy Drug (Nivolumab) to the Usual Chemotherapy Treatment (Cisplatin or Carboplatin With Gemcitabine) for Recurrent or Metastatic Nasopharyngeal Cancer

Recurrent Nasopharyngeal Carcinoma | Stage IV Nasopharyngeal Carcinoma AJCC v8 | Metastatic Nasopharyngeal Carcinoma | Metastatic Nasopharyngeal Keratinizing Squamous Cell Carcinoma | Metastatic Nasopharyngeal Nonkeratinizing Carcinoma | Metastatic Nasopharyngeal Undifferentiated Carcinoma | Nasopharyngeal... and other conditions

United States, Canada, China, Singapore
DermaGen AB
Pergamum AB

Completed

A Study of DPK-060 to Investigate Clinical Safety and Efficacy in Patients With Acute External Otitis

Acute Otitis Externa

Sweden
M.D. Anderson Cancer Center

Active, not recruiting

Etigilimab and Nivolumab for the Treatment of Platinum-Resistant Recurrent Clear Cell Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Recurrent Platinum-Resistant Ovarian Carcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Ovarian Clear Cell Adenocarcinoma | Recurrent Platinum-Resistant Fallopian Tube Carcinoma | Recurrent Platinum-Resistant Primary Peritoneal Carcinoma | Recurrent Primary Peritoneal...

United States

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