Search clinical trials for: Caffeine abstinence

Total 555 results

Pfizer

Completed

Drug-Drug Interaction Study With PF-05089771

Healthy

Belgium
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Effect of Polymorphisms in the Adenosine a2a Receptor Gene and AMPD2 Gene on Adenosine-Induced Vasodilation and Reactive Hyperemia

Blood Flow in Healthy Volunteers

Netherlands
Zagazig University

Completed

Management of Post Dural Pucture Headache After Lower Limb Surgeries: Oral Prednisolone vs Oral Pregabalin

Analgesia

Egypt
RAI Services Company

Not yet recruiting

CSD231005 Nicotine Pouch Biomarkers of Exposure

Smoking | Tobacco Use

United States
Ethicon Endo-Surgery
Novella Clinical; Data & Inference, Inc.

Completed

Safety and Effectiveness of a Non-invasive Neuromodulation Device on Urgency Urinary Incontinence in Overactive Bladder (Beacon)

Overactive Bladder

United States
VA Office of Research and Development

Recruiting

CPT-SMART for Treatment of PTSD and Cigarette Smoking (CPT-SMART)

Smoking | Stress Disorders, Post-Traumatic

United States
Duke University

Recruiting

Oxygen Toxicity: Mechanisms in Humans

Seizures | Hypercapnia | Oxygen Toxicity

United States
Beni-Suef University
University of Arizona; Maternity and Children Hospital, Makkah; Beni-Suef Health...

Completed

Hydroxy Urea, Omega 3, Nigella Sativa,Honey on Oxidative Stress and Iron Chelation in Pediatric Major Thalassemia

Iron Overload | Oxidative Stress | Thalassemia Major

Egypt, Saudi Arabia
Amsterdam UMC, location VUmc

Withdrawn

REGROUP: Renohemodynamic Effects empaGliflozin in vaRiOUs Populations (REGROUP)

Diabetes Mellitus, Type 2 | Chronic Kidney Diseases
University of Oklahoma

Terminated

EIMD Mechanisms Causing Force Loss

Healthy

United States
Repros Therapeutics Inc.

Completed

Open-Label, Multiple-Dose, Non-Randomized Study to Assess Drug-Drug Interactions of Proellex® in Female Subjects

Drug Interactions

United States
AstraZeneca

Completed

Drug Interaction Study Between AZD3480 and Cytochrome P450 (Cocktail)

Alzheimer's Disease | Metabolism

Sweden
Bruce Pollock
National Institute of Mental Health (NIMH)

Completed

Serotonergic Pharmacotherapy for Agitation of Dementia (SPAD)

Dementia | Alzheimer Disease | Dementia, Vascular

United States
Pennington Biomedical Research Center

Completed

"Pecos" B-adrenergic and PPAR-G Stimulation Upregulates Lipid Metabolism in Human Subcutaneous Fat

Obesity

United States
McGill University Health Centre/Research Institute...
Canadian Institutes of Health Research (CIHR)

Unknown

Follow up Treatment of Children With Attention Deficit Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder (ADHD)

Canada
University of Monastir

Not yet recruiting

Paracetamol-Tramadol and Paracetamol-caffeine Versus Placebo in the Emergency Discharge Treatment of Renal Colic (RC)

Renal Colic
Boehringer Ingelheim

Completed

To Determine Blood Concentrations of Ibuprofen and Caffeine in a Tablet Against Ibuprofen Alone From Another Tablet

Healthy

South Africa
Swiss Paraplegic Centre Nottwil

Completed

Caffeine and Sodium Citrate Ingestion

Wheelchairs | Dietary Supplements | Heart Rate/Drug Effects | Lactic Acid/Metabolism | Physical Education and Training/Methods

Switzerland
Eli Lilly and Company

Completed

A Study of Ixekizumab in Participants With Plaque Psoriasis

Psoriasis

United States
Wayne State University
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Smoking Cessation for People Living With HIV/AIDS

HIV | Nicotine Dependence | AIDS

United States
Bristol-Myers Squibb

Completed

Drug Interaction Study With a Potential Alzheimer's Disease Compound

Alzheimer Disease

United States
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Comparison of Biological Therapies Following Combination Chemotherapy and Bone Marrow or Peripheral Stem Cell Transplantation in Women With Stage II or Stage III Breast Cancer

Breast Cancer

United States
Boehringer Ingelheim

Completed

The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)

Healthy

Germany
Eli Lilly and Company

Completed

A Drug-Drug Interaction (DDI) Study of LY3437943 in Obese Participants

Obesity

United States
Thomas Stauffer Larsen

Completed

A Study of Low Dose Interferon Alpha Versus Hydroxyurea in Treatment of Chronic Myeloid Neoplasms (DALIAH)

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia

Denmark
Virginia Commonwealth University
University of Louisville

Completed

Hepatic Drug Biotransformation in Children With Obstructive Sleep Apnea

Sleep Apnea

United States
Novartis Pharmaceuticals

Completed

A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors

cMET-dysregulated Advanced Solid Tumors

United States, Spain, Italy, Bulgaria, United Kingdom, France, Denmark
Hospital Universitari Vall d'Hebron Research Institute

Completed

Efficacy of Caffeine, With and Without Biperiden, in the Detoxification of Cocaine Dependent Patients

Cocaine Related Disorders

Spain
AstraZeneca

Completed

Effect of Multiple Doses of AZD6280 on the Pharmacokinetics of Midazolam (CYP3A4) and Caffeine (CYP1A2) (CYP)

Healthy

United Kingdom
AstraZeneca

Completed

Determine the Effect of Multiple Doses of AZD7325, CYP Study (CYP)

Healthy Volunteer
Heartfelt Technologies

Not yet recruiting

Randomised Controlled Trial for Assessing the Effectiveness of an Inclusive Heart Failure Monitoring and TRACKing Solution in the UK. (HF-TRACK)

Heart Failure

United Kingdom
InterMune

Completed

Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States, Peru
Janssen Research & Development, LLC

Suspended

A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Active Crohn's Disease or Ulcerative Colitis

Crohn Disease | Ulcerative Colitis

Germany, United States, Belgium, United Kingdom
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Study Of Fluzoparib (SHR3162) on Patients With Recurrent Ovarian Cancer

Recurrent Ovarian Cancer

China
Centre Hospitalier Universitaire de Nice

Completed

Role of Topical Treatments in the Modulation of Skin Microbiome in Psoriatic Skin (Microbiome&Pso)

Psoriasis Vulgaris

France
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How Daily Dosing With Enzalutamide Affects the Metabolism of Caffeine and Dextromethorphan in Men With Prostate Cancer

Prostate Cancer | Pharmacokinetics of Dextromethorphan | Pharmacokinetics of Caffeine

Moldova, Republic of
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

The Effects of Multiple Dose Fluoxetine and Metabolites on CYP1A2, CYP2C19, CYP2D6 and CYP3A4 Activity (FLUOXETINE)

Healthy Volunteers | Drug-Drug Interaction
Janssen Research & Development, LLC

Completed

A Study to Assess Effect of JNJ-54861911 on Pharmacokinetics of Cocktail Representatives for Cytochrome P450 (CYP) 3A4, CYP2B6, CYP2C9, and CYP1A2 Substrates

Healthy

Netherlands
Queen's University
H. Lundbeck A/S

Completed

Specific Effects of Escitalopram on Neuroendocrine Response

Healthy

Canada
The Alfred

Unknown

A Study Comparing Continuous Infusion Antibiotics to Standard Treatment for Lung Infections in Cystic Fibrosis (CISTIC)

Cystic Fibrosis

Australia
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Oral Doses of JNJ-54175446 on the Inhibition of Cytochrome P450 CYP3A4, CYP2C9, CYP1A2 and CYP2D6 Activity and the Induction of CYP2B6 and CYP2C19 Activity Using a Multiple Probe Substrate Cocktail in Healthy Subjects

Healthy

Belgium
Tel Aviv University
Zohar Landau; Shani Tsameret

Unknown

Influence of Dairy Protein Breakfast on Glycemia, Weight Loss and Clock Genes in T2D (Mdiet)

Type2 Diabetes | Healthy Obesity, Metabolically

Israel
Boehringer Ingelheim

Completed

Acetylsalicylic Acid (ASA) + Paracetamol + Caffeine Combination Compared With ASA + Paracetamol as Well as ASA, Paracetamol, and Caffeine in Headache Patients

Migraine Disorders
Centre hospitalier de l'Université de Montréal...
Canadian Institutes of Health Research (CIHR)

Completed

Evaluation of CYP450 Activities in Diabetic Patients vs. Non-diabetic Subjects

Type 2 Diabetes

Canada
Chonbuk National University Hospital

Completed

Clinical Trials on Evaluate the Red Ginseng and Fermented-Red Ginseng Affect to Drug Metabolizing Enzyme and Transporter in Healthy Volunteers

Healthy

Korea, Republic of
Genentech, Inc.

Completed

A Study of GDC-0134 to Determine Initial Safety, Tolerability, and Pharmacokinetic Parameters in Participants With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

United States, Netherlands, Canada
Hospital Central Norte PEMEX

Completed

Abdominal Binder in Colonoscopies Performed by Trainees

Performance of Colonoscopy | Tolerance of Colonoscopy

Mexico
Hadassah Medical Organization

Unknown

Metabolic Capacity of Israeli Populations

Healthy Volunteers

Israel
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Unknown

Imaging the Effects of Zolpidem and Alprazolam in Healthy Volunteers at 3T

Psychotropic Drugs Effects

United States
Jules Desmeules

Completed

Evaluation of the Potential Pharmacokinetic Interactions Between Probe Drugs in the Geneva Phenotyping Cocktail

Drug Interaction

Switzerland

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