Search clinical trials for: calcineurin inhibitor

Total 64012 results

Centre Hospitalier Universitaire, Amiens

Withdrawn

Evaluation of Interaction Between Immunosuppressive Drugs and Protein-bound Uremic Toxins in Renal Transplant Patients (DRUGTOX)

Immunosuppression | Kidney Transplant | Uremic; Toxemia

France
University of Wisconsin, Madison

Completed

Campath-1H Induction to Allow Discontinuation of Calcineurin Inhibitors After Renal Transplantation

Primary Renal Transplant

United States
Incyte Corporation

Terminated

GRAVITAS-119: Itacitinib in Combination With Calcineurin Inhibitor-Based Interventions for the Prophylaxis of Graft-Versus Host Disease

Hematologic Malignancies

United States, Spain, France, Italy
The University of Western Australia
Royal Brisbane and Women's Hospital; Fremantle Hospital and Health Service; Royal... and other collaborators

Completed

Rectal Tacrolimus in the Treatment of Resistant Ulcerative Proctitis

Ulcerative Colitis

Australia
University Hospital, Grenoble
National Agency for Research on AIDS and Viral Hepatitis (ANRS)

Not yet recruiting

Viral Immunity in Solid Organ Transplant Recipients: Monitoring Of The Response To Hepatitis B Booster Vaccination (VITAMIN)

Liver Transplantation | Kidney Transplantation | HBV

France
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis on Background Topical Corticosteroids (SHORE)

Dermatitis Atopic

Japan, Chile, Canada, United States
Sanofi

Recruiting

Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials (RIVER-AD)

Dermatitis Atopic

Canada, United States, Australia, Bulgaria, Czechia, Germany, Hungary, Japan, Poland, Spain, Taiwan, United Kingdom
Assistance Publique - Hôpitaux de Paris
Novartis

Completed

The Efficacy of Everolimus in Reducing Total Native Kidney Volume in Polycystic Kidney Disease Transplanted Recipients (EVERKYSTE)

Autosomal Dominant Polycystic Kidney Disease

France
Nilratan Sircar Medical College

Recruiting

Efficacy and Safety of Rituximab to That of Calcineurin Inhibitors in Children With Steroid Resistant Nephrotic Syndrome

Nephrotic Syndrome

India
Nilratan Sircar Medical College

Completed

Efficacy and Safety of Rituximab to That of Calcineurin Inhibitors in Children With Steroid Dependent Nephrotic Syndrome

Nephrotic Syndrome

India
Sanofi
Regeneron Pharmaceuticals

Completed

Study of Dupilumab for the Treatment of Patients With Prurigo Nodularis, Inadequately Controlled on Topical Prescription Therapies or When Those Therapies Are Not Advisable (PRIME2)

Neurodermatitis

United States, Canada, Chile, France, Hungary, Italy, Korea, Republic of, Portugal, Spain, Taiwan, United Kingdom
Sanofi
Regeneron Pharmaceuticals

Completed

Study of Dupilumab for the Treatment of Patients With Prurigo Nodularis, Inadequately Controlled on Topical Prescription Therapies or When Those Therapies Are Not Advisable (LIBERTY-PN PRIME)

Neurodermatitis

France, United States, Argentina, China, Japan, Korea, Republic of, Mexico, Russian Federation
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Guangzhou First... and other collaborators

Unknown

MSCs Combined With CD25 Monoclonal Antibody and Calcineurin Inhibitors for Treatment of Steroid-resistant aGVHD

Acute Graft-versus-host Disease

China
Hospital Israelita Albert Einstein

Terminated

Comparison Between Cyclophosphamide and Combination of Methotrexate + Calcineurin Inhibitor for GVHD Prophylaxis (CICLODECH)

Chronic Myelomonocytic Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Acute Lymphoid Leukemia | Myeloproliferative Disease

Brazil
Hospital Clinic of Barcelona

Unknown

Effect of Rapamycin on Tolerance-related Biomarkers on Stable Liver Transplant Recipients

Liver Transplantation

Spain
Bristol-Myers Squibb

Completed

Belatacept and Risk of Post-transplant Lymphoproliferative Disorder in US Renal Transplant Recipients

Kidney Transplantation | Transplantation, Kidney
Nair, Vinay, D.O.
Bristol-Myers Squibb; Icahn School of Medicine at Mount Sinai

Unknown

Early Conversion From CNI to Belatacept in Renal Transplant Recipients With Delayed and Slow Graft Function

Kidney Transplant | Delayed Graft Function

United States
University of Cincinnati
Roche Pharma AG

Completed

Pilot Study for HLA Identical Living Donor Renal Transplant Recipients

Renal Transplant

United States
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 1)

Dermatitis Atopic

Israel, Chile, Australia, United States, Canada, Korea, Republic of
Federal Research Institute of Pediatric Hematology...

Active, not recruiting

Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Calcineurin Inhibitor at Patients With Hemoblastosis

Myelodysplastic Syndromes | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Myeloblastic Leukemia | Malignant Lymphoma | Biphenotypic Acute Leukemia

Russian Federation
Uppsala University

Completed

Malignancies in Transplanted Patients (MALTX)

Neoplasms

Sweden
Deise de Boni Monteiro de Carvalho

Unknown

Study to Evaluate the Safety and Efficacy of Switching Calcineurin Inhibitor to Everolimus After Kidney Transplantation in Adults

Immunosuppression | Kidney Transplant

Brazil
Hannover Medical School

Unknown

Studying the Effect of Changing Immunosuppression in Case of Polyoma BK Virus Infection of the Renal Transplant (BKVIRUS)

Virus Diseases | Disorder Related to Renal Transplantation | Immunosuppression Related Infectious Disease

Germany
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Completed

Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver Transplant (A-WISH)

Hepatitis C | Hepatitis C, Chronic | Nonimmune Nonviral Causes of Liver Failure

United States
Novartis Pharmaceuticals

Completed

ASCERTAIN: Assessment of Everolimus in Addition to Calcineurin Inhibitor Reduction in the Maintenance of Renal Transplant Recipients

Renal Transplantation

Switzerland
Hoffmann-La Roche

Completed

Kidney Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Kidney Transplant Recipients

Kidney Transplantation

United States
Centre Hospitalier Departemental Vendee

Recruiting

Glucose Disorders Induced by Tacrolimus on Pre Transplantation Endstage Renal Disease Patients (GLITTER)

Kidney Failure, Chronic

France
Massachusetts General Hospital

Withdrawn

A Pilot Open Labeled Study of Tacrolimus in Alzheimer's Disease.

Alzheimer Disease | Mild Cognitive Impairment
The Third Xiangya Hospital of Central South University
Hunan Provincial People's Hospital; ZhuZhou Central Hospital; First People's...

Unknown

Population Pharmacokinetics of Tacrolimus in Nephrotic Syndrome (PISTONS)

Pharmacokinetics | Nephrotic Syndrome | Tacrolimus
Janssen-Cilag Ltd.,Thailand

Completed

An Efficacy and Safety Study of Tacrolimus Ointment in Pediatric Participants With Atopic Dermatitis

Dermatitis, Atopic

Vietnam
Astellas Pharma Inc

Completed

A Study to Assess Efficacy, Safety and Pharmacokinetics of a Tacrolimus New Oral Formulation (MR4) in BMT Recipients

Bone Marrow Transplantation | Graft Versus Host Disease | Graft-Versus-Host Disease | Graft-Vs-Host Disease

Japan
Mayo Clinic

Completed

Use of Sublingual Tacrolimus in Adult Blood and Marrow Transplant Patients

Stem Cell Transplant | Immunosuppression | Bone Marrow Transplant

United States
Singapore General Hospital

Active, not recruiting

Efficacy of Achieving Early Target Trough Levels of Tacrolimus Using CYP3A5 Guided Dosing Versus Weight-based Dosing in a Multi-ethnic Population of Kidney Transplant Recipients in Singapore

Kidney Transplant Rejection | Kidney Transplant; Complications

Singapore
Seoul National University Hospital

Completed

a Comparative Pharmacokinetic Study of Two Oral Formulations of Tacrolimus in Renal Allograft Recipients

Pharmacokinetics | Tacrolimus

Korea, Republic of
University of California, Davis

Withdrawn

Evaluation to Assess the Long Term Safety of Tacrolimus Ointment for Atopic Dermatitis

Atopic Dermatitis
Janssen-Cilag Ltd.,Thailand

Completed

An Efficacy and Safety Study of Tacrolimus Ointment in Adult Participants With Atopic Dermatitis

Dermatitis, Atopic

Vietnam
Centre Hospitalier Universitaire, Amiens
Roche Pharma AG; Astellas Pharma Inc

Completed

TACrolimus in Renal Transplantation: Individualization by Pharmacogenetic

Kidney Transplantation

France
Astellas Pharma Inc

Completed

A Study to Assess the Safety and Efficacy of a Tacrolimus New Oral Formulation (MR4) in BMT Patients-Extension-

Bone Marrow Transplantation | Graft Versus Host Disease | Graft-Versus-Host Disease | Graft-Vs-Host Disease

Japan
National Center for Research Resources (NCRR)

Completed

Pharmacokinetics of Tacrolimus in Kidney Transplant Recipients: Once Daily Versus Twice Daily Dosing

Kidney Transplantation

United States
Chiesi Hungary Ltd.
Chiesi Slovenija, d.o.o.

Recruiting

Assessment of the Pharmacokinetic Profile of Tacrolimus Medications and Their Relation to Effectiveness and Safety in Liver Transplant Patients (LTA)

Liver Failure

Hungary, Slovenia
UNC Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill

Completed

Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplant (HCT)

Acute GVHD

United States
Seoul National University Hospital
Chong Kun Dang Pharmaceutical

Completed

Therapeutic Effect of Tacrolimus on Primary Nephrotic Syndrome in Children

Nephrotic Syndrome

Korea, Republic of
Pontificia Universidad Catolica de Chile

Completed

Determining Equivalence Dose for Oral Versus Sublingual Administration of Tacrolimus in Hepatic Receptors (FKosl)

Evidence of Liver Transplantation | Effects of Immunosuppressant Therapy

Chile
Seoul National University Hospital

Completed

Therapeutic Effect of Tacrolimus in Combination With Low Dose Corticosteroid in Adult Patient With Minimal Change Nephritic Syndrome (MCNS)

Minimal Change Disease

Korea, Republic of
Maastricht University Medical Center

Unknown

Pharmacokinetic Study to Rectal and Sublingual Administration of Tacrolimus in Future Kidney Transplant Patients

Organ Transplantation

Netherlands
University of California, Los Angeles
Food and Drug Administration (FDA)

Completed

Prospective Study Comparing Brand and Generic Immunosuppression on Transplant Outcomes, Adherence, & Immune Response in Kidney Transplant Recipients

Renal Transplant Rejection

United States
University Hospital Heidelberg

Unknown

Evaluation of the Impact of Tacrolimus-based Immunosuppression on Heidelberg Liver Transplant Cohort (HDTACRO): Study Protocol for an Investigator Initiated, Non-interventional Prospective Study

Liver Transplantation

Germany
Shandong University

Completed

Pharmacokinetics of Tacrolimus in Children

Nephrotic Syndrome
Rennes University Hospital

Completed

Therapeutic Drug Monitoring of Tacrolimus Biliary Concentrations for Liver-transplanted Patients (STABILE) (STABILE)

Biliary Concentration of Tacrolimus

France
Nantes University Hospital

Terminated

Protocol Calcineurin Inhibitor (CNI) Weaning

Function of Renal Transplant

France

Search clinical trials for: calcineurin inhibitor

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