Search clinical trials for: Chloride Channel Agonists

Total 24078 results

Medical University of Vienna

Unknown

Amiloride Hydrochlorothiazide as Treatment of Acute Inflammation of the Optic Nerve

Optic; Neuritis, With Demyelination

Austria
Hospital de Clinicas de Porto Alegre
Financiadora de Estudos e Projetos

Completed

Diuretics and Angiotensin-Receptor Blocker Agents in Patients With Stage I Hypertension (PREVER)

Hypertension | Cardiovascular Disease

Brazil
University of Saskatchewan

Completed

Methacholine Challenge: Comparison of Doubling and Quadrupling Methacholine Dose Regimes Using the Tidal Volume Method

Asthma

Canada
Fernando Bacal

Recruiting

Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation (HSS-HT)

Heart Transplantation | Acute Kidney Injury

Brazil
Stanford University

Withdrawn

Small-Volume, Patient-Specific, Balanced Hypertonic Fluid Protocol Validation

Cerebral Edema | Saline Solution, Hypertonic

United States
Novartis

Completed

Efficacy and Tolerability of an Aliskiren-based Treatment Algorithm in Patients With Mild to Moderate Hypertension

Essential Hypertension ( Mild to Moderate)

Romania, Slovakia, Hungary, France
Menoufia University

Recruiting

Hemodynamic Responses of Dexmedetomidine, Lidocaine or Propofol Infusions During Laparoscopic Cholecystectomy

Dexmedetomidine | Laparoscopic Cholecystectomy | Propofol | Lidocaine | Hemodynamic Responses

Egypt
Kasr El Aini Hospital

Recruiting

A Comparative Study to Measure the Effect of Nebulized Dexmedetomidine

Dexmedetomidine | Tonsillectomy | Lidocaine

Egypt
Menoufia University

Completed

Dexmedetomidine in IVRA

Regional Anesthesia Morbidity

Egypt
University of Sao Paulo General Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo

Unknown

Dental Anesthesia in Heart Failure Patients (DAHFP)

Heart Failure

Brazil
Bezmialem Vakif University

Completed

Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy

Chronic Cholecystitis

Turkey
Assiut University

Not yet recruiting

Block Pressor Response to Intubation

Intubation Complication
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis

Cystic Fibrosis

United States, Israel, Ireland, United Kingdom
Aga Khan University
Zeenat Qureshi Stroke Institute

Recruiting

Best Solution Identification to Prevent Hyperchloremia Combinations of Sodium Chloride and Sodium Acetate IV Fluids Along With Standard of Care Treatment in Acute Stroke Patients (sodium acetate)

Stroke, Acute

Pakistan
Soonchunhyang University Hospital

Unknown

Spray vs EMLA Cream on Pain During Intra-articular Injection

Adhesive Capsulitis of the Shoulder

Korea, Republic of
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; University of Cambridge

Terminated

A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems (PRIME)

Drug-Related Side Effects and Adverse Reactions | Cardiovascular System Disease

United Kingdom
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Reduced Contractile Reserve: a Therapeutic Target in Heart Failure With Preserved Ejection Fraction(HFpEF)

Pulmonary Disease | Heart Failure With Preserved Ejection Fraction | Left Ventricular Hypertrophy/Hypertension

United States
Samsung Medical Center

Recruiting

Modulating Surgery-Induced Blood-Brain Barrier Disruption in Elderly

Delirium, Postoperative

Korea, Republic of
Louisiana State University Health Sciences Center...

Completed

Use of CBCT to Improve Inferior Alveolar Nerve Block Success

Inferior Alveolar Nerve | Mandibular Nerve Blocks

United States
Women's College Hospital

Completed

The Effect of the Serratus Block on Pain Control After Breast Surgery

Anesthesia

Canada
Cambridge University Hospitals NHS Foundation Trust
King's College London

Not yet recruiting

Skin Sodium and Salt Sensitivity of Blood Pressure (INTREPID)

Hypertension

United Kingdom
Novartis

Completed

A Long Term Safety Study to Test the Combination of Aliskiren/ Amlodipine / Hydrochlorothiazide in Participants With Essential Hypertension

Essential Hypertension

Spain, United States, Belgium, Egypt, Germany, Poland, Slovakia, Turkey
Erasmus Medical Center

Completed

Thiazide Diuretics for Hypertension in Kidney Transplant Recipients Using Tacrolimus (TT)

Hypertension | Kidney Transplantation

Netherlands
Novartis

Completed

An Assessment of Long Term Safety of the Combination of Aliskiren / Amlodipine in Patients With High Blood Pressure

Hypertension

United States, Belgium, Denmark, Finland, Germany, Iceland, India, Switzerland
University of Edinburgh
NHS Lothian

Completed

Intraoperative Cell Salvage and Postoperative Acidosis

Metabolic Acidosis

United Kingdom
Peking Union Medical College Hospital

Not yet recruiting

Efficacy of Sr-89 for Differentiated Thyroid Cancer With Bone Metastases

Bone Metastases | Thyroid Neoplasm Follicular

China
Insel Gruppe AG, University Hospital Bern

Recruiting

Crystalloid Fluid Choice and Neurological Outcome in Patients After Subarachnoid Haemorrhage (CRYSTALLBrain)

Critical Illness | Subarachnoid Hemorrhage | Sodium Disorder | Infusion Fluid

Switzerland
Children's Hospital Medical Center, Cincinnati
University of Cincinnati

Terminated

Sodium Supplementation and Growth in Very Low Birth Weight Infants (SSALT)

Extreme Immaturity

United States
University of East Anglia

Unknown

Nitrite Effects on Cardiac Muscle in CABG

Vascular Diseases | Coronary Artery Disease | Diabetes Mellitus | Atherosclerosis | Cardiac Disease

United Kingdom
University Hospital, Clermont-Ferrand

Unknown

Comparative Evaluation of the Effect on Blood Pressure of an Equivalent Content of Sodium in the Form of Bicarbonate of Sodium and in the Form of Sodium Chloride, on "Sensitive Sodium" Subjects (SODIVASC)

Healthy

France
Eli Lilly and Company

Completed

The Effects of Urinary pH Changes on an Investigational Compound in Healthy Subjects

Healthy Subjects

United Kingdom
Pontificia Universidad Catolica de Chile

Completed

Effect of Dexmedetomidine on Postoperative Glucose and Insulin Levels.

Insulin Resistance | Glucose Intolerance | Bariatric Surgery Candidate
Novartis

Completed

Blood Pressure Lowering of Aliskiren HCTZ Compared to HCTZ in Stage 2 Systolic Hypertension in Older Population (ACTION)

Hypertension

United States
Alexandria University

Recruiting

Immunomodulatory Effects of Dexmedetomidine Infusion

Major Abdominal Surgery

Egypt
University Hospital, Brest
Baxter Healthcare Corporation; Direction Générale de l'Offre de Soins

Completed

Dexmedetomidine After Cardiac Surgery for Prevention of Delirium (EXACTUM)

ICU Delirium

France
Kaohsiung Medical University Chung-Ho Memorial...

Unknown

Comparison of the Effect of Intravenous and Perineural Dexmedetomidine in Gastric Cancer Surgery

Pain, Postoperative | Gastric Cancer

Taiwan
InVasc Therapeutics, Inc.

Completed

Study to Determine the Effects of Nebivolol and Hydrochlorothiazide in African Americans With Hypertension (NASAA)

Hypertension

United States
University of Zurich

Completed

Painless Local Anaesthesia With Bicarbonate Admixture

Anesthesia | Local Infiltration

Switzerland
CMC Ambroise Paré

Completed

Dexmedetomidine Intra Venous Arthroplasty (DIVA)

Primary Total Knee Arthroplasty

France
University of Galway
Health Research Board, Ireland

Not yet recruiting

SalT Supplementation in Older Adults With Orthostatic Intolerance Disorders (STOOD)

Orthostatic Hypotension
University of Missouri-Columbia

Withdrawn

Effects of 3% Sodium Chloride on Post-operative Dysphagia Following Anterior Cervical Spine Surgery

Dysphagia
Fab'entech

Completed

Safety and Pharmacokinetics Study of FBF001

Avian Influenza
University Hospital Birmingham NHS Foundation Trust

Unknown

Nitrite Mediated Cardioprotection During Coronary Artery Bypass Surgery

Coronary Artery Bypass Surgery

United Kingdom
University of Malaya

Recruiting

Analgesic Effect of IntraPeritoneal LIGNOcaine in Gynaecological Open Surgery

Postoperative Pain | Gynecologic Disease | Local Anesthetic Systemic Toxicity

Malaysia
Vanderbilt University Medical Center
University of Calgary

Enrolling by invitation

Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers

Anesthesia, Local | Ehlers-Danlos Syndrome

United States
Bryon Adinoff
National Institute on Drug Abuse (NIDA)

Completed

Lidocaine Infusion as a Treatment for Cocaine Relapse and Craving (LIDO)

Cocaine Addiction

United States
GlaxoSmithKline

Completed

The Safety, Tolerability, PK and PD of GSK2339345 in Healthy Subjects (FTIH)

Cough

United Kingdom
Rhode Island Hospital

Terminated

Hematoma Block as an Adjunct to Procedural Sedation for Forearm Fracture Reduction

Forearm Fracture

United States
Asan Medical Center
Korea Health Industry Development Institute

Completed

Association Between Pre-op Non-Selective Beta-Blockers and Hepatocellular Carcinoma Recurrence Post-Liver Transplant

Hepatocellular Carcinoma | Hepatocellular Carcinoma Recurrent
Cambridge University Hospitals NHS Foundation Trust
Medical Research Council

Recruiting

Comparison of Optimal Hypertension Regimens (AIMHY-INFORM)

Hypertension

United Kingdom

Search clinical trials for: Chloride Channel Agonists

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mali

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations