Search clinical trials for: Classic DMARDs treatment group

Total 752 results

Oregon Weight Loss Surgery, LLC

Completed

Treatment of Low Metabolic Rate Following Bariatric Surgery

Morbid Obesity

United States
AstraZeneca

Terminated

Symbicort Single Inhaler Therapy vs Conventional Best Practice for the Treatment of Persistent Asthma in Adults

Asthma, Bronchial

Spain
Xijing Hospital

Completed

Neoadjuvant Endostatin and Chemotherapy for Breast Cancer

Breast Cancer

China
University Health Network, Toronto
Organon

Completed

Sedating Antidepressant Improves Driving Safety in Patients With Major Depressive Disorder

Depression | Excessive Daytime Sleepiness

Canada
The University of Texas Health Science Center,...

Unknown

The Evaluation of Postoperative Antibiotics in Non-Infected Mandible Fractures

Infection | Jaw Fractures

United States
Universiti Sains Malaysia

Unknown

Granisetron vs Granisetron and Dexamethasone on the Reduction of Postoperative Nausea and Vomiting

PONV

Malaysia
Makassed General Hospital

Completed

Ondansetron vs Ondansetron Plus Dexamethasone for Relieving Intrathecal Morphine Side Effects After C-section

Cesarean Section | Pruritus

Lebanon
Otsuka Beijing Research Institute

Completed

Study of Cilostazol and Probucol to Assess Their Effects on Atherosclerosis Related Biomarker

Type 2 Diabetes Mellitus | Arteriosclerosis Obliterans

China
Tianjin Medical University Cancer Institute and...

Enrolling by invitation

AC-CHOP Versus CHOP in Patients With Previously Untreated PTCL-TFH

Peripheral T-cell Lymphoma Targeted Therapy

China
McGill University Health Centre/Research Institute...
Canadian Institutes of Health Research (CIHR)

Unknown

Cognitive Behavioral Therapy for Adolescents With Attention-Deficit / Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

Canada
Istituto Auxologico Italiano
Università Politecnica delle Marche; University of Milan

Completed

Effect on Energy Metabolism at Cellular Level of Diet Plus Treatment With Ephedrine and Caffeine in Obesity

Obesity

Italy
Azienda Sanitaria dell'Alto Adige

Recruiting

Pericapsular Nerve Group Block for Positional Pain and Postoperative Analgesia in Hip Fractures

Pain, Postoperative | Pertrochanteric Fracture

Italy
Merck Sharp & Dohme LLC

Terminated

Efficacy of Infliximab in the Treatment of Patients Affected by Corticodependent Crohn's Disease (P02732)

Crohn's Disease
GlaxoSmithKline

Completed

A Study to Assess the Efficacy of Fluticasone Furoate/Vilanterol (FF/VI) Inhalation Powder 100/25 mcg Once Daily Compared With Fluticasone Propionate/Salmeterol Inhalation Powder 250/50 mcg Twice Daily in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, Romania, Russian Federation, United States, Ukraine
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Study to Evaluate the Mastery of Inhaler Technique for Budesonide Formoterol (BF) SPIROMAX® as Compared to SYMBICORT® TURBOHALER® as Treatment for Adult Participants With Asthma (ELIOT)

Asthma

United Kingdom
University of Campinas, Brazil
Texas Tech University

Completed

Microneedle Pretreatment as a Strategy to Improve the Effectiveness of Topical Anesthetics Formulations

Oral Cavity Disease

Brazil
Peking Union Medical College Hospital

Recruiting

Zanubrutinib Combined With R-CHOP in Newly-diagnosed Intravascular Large B-cell Lymphoma

Intravascular Large B-Cell Lymphoma

China
Kyowa Kirin Co., Ltd.

Completed

A Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or Rosuvastatin

Parkinson's Disease

Japan
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Chemotherapy With or Without Biological Therapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy

Prostate Cancer

United States
King Faisal Specialist Hospital & Research Center

Completed

The Placebo Effect May Involve Modulating Drug Bioavailability

Pharmacokinetics | Placebo Effect | Drug Half Life

Saudi Arabia
Boehringer Ingelheim

Completed

The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)

Healthy

Germany
German Breast Group

Completed

Adjuvant Chemotherapy for Elderly Non Frail Patients With an Increased Risk for Relapse of a Primary Carcinoma of the Breast (ICE-II)

Breast Cancer

Germany
Sun Yat-sen University

Unknown

Liver Resection Versus Transarterial Chemoembolization for the Treatment of Intermediate-stage Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Compare The Ability of Different Anti-HIV Drugs to Decrease Viral Load After Nelfinavir (an Anti-HIV Drug)Treatment Failure

HIV Infections

United States, Puerto Rico
MaineHealth
Robert Wood Johnson Foundation

Completed

Early Detection and Intervention for the Prevention of Psychosis (EDIPP)

Depression | Psychotic Disorders | Schizophrenia | Bipolar Disorder

United States
University of California, San Diego
National Cancer Institute (NCI)

Terminated

Allogeneic Stem Cell Transplant After ATG, High-Dose Melphalan, and Fludarabine for Patients With Breast Cancer

Breast Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Antiemetic Therapy With or Without Olanzapine in Preventing Chemotherapy-Induced Nausea and Vomiting in Patients With Cancer Receiving Highly Emetogenic Chemotherapy

Unspecified Adult Solid Tumor, Protocol Specific | Hematopoietic/Lymphoid Cancer | Nausea and Vomiting

United States
AstraZeneca
Quintiles, Inc.

Completed

Effects of AZD1775 on the PK Substrates for CYP3A, CYP2C19, CYP1A2 and on QT Interval in Patients With Advanced Cancer

Solid Tumours

United States
Novartis Pharmaceuticals

Completed

Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors

Advanced Solid Tumors, Excluding Breast Cancer

United States
Daiichi Sankyo, Inc.
Medpace, Inc.

Completed

Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer Subjects

Solid Tumors

United States
EMS

Completed

Efficacy and Safety of the Combination of Ketoprofen and Cyclobenzaprine and Caffeine in Osteomuscular Treatment

Musculoskeletal Pain

Brazil
Merck Sharp & Dohme LLC

Completed

A Single-Dose Study to Investigate the Pharmacokinetics of MK-7655 in Participants With Impaired Renal Function (MK-7655-005)

Infectious Disease
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Participants Greater Than or Equal to (>=)1 and Less Than or Equal to (<=) 30 Years of Age With Relapsed/Refractory Precursor B-cell or T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Precursor Cell Lymphoblastic Leukemia-Lymphoma

United States, United Kingdom, France, Sweden, Germany, Spain, Italy, Belgium, Israel, Netherlands
Kadmon Corporation, LLC
Quotient Sciences

Completed

Drug-drug Interaction Between Belumosudil, Itraconazole, Rifampicin, Rabeprazole, and Omeprazole in Healthy Volunteers

Autoimmune Diseases | Drug-drug Interaction | Fibrotic Disease

United Kingdom
Rabin Medical Center
Tel Aviv University; The Leona M. and Harry B. Helmsley Charitable Trust

Recruiting

Biomarker-based Multidisciplinary Team (Bio-MDT) Approach to Personalized Microbial-targeted Treatment of Pouchitis and Crohn's Disease (Bio-MDT)

Inflammatory Bowel Diseases

Israel
Astellas Pharma Inc
Astellas Pharma Canada, Inc.

Completed

Comparison of Standard Versus Low Dose Advagraf® With or Without Angiotensin-converting Enzyme Inhibitor (ACEi)/Angiotensin Receptor Blocker (ARB) on Histology and Function of Renal Allografts

Kidney Transplantation

Canada
Boehringer Ingelheim

Completed

Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers

Healthy
Boehringer Ingelheim

Completed

Effects of BI 201335 NA on Cytochrome P450 and P-glycoprotein Activity Using a Probe Drug Cocktail in Healthy Volunteers

Healthy
The George Institute
National Health and Medical Research Council, Australia

Completed

Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage

Intracranial Hemorrhages | Cerebral Hemorrhage | CVA (Cerebrovascular Accident)

Australia, New Zealand, China
Chonbuk National University Hospital

Completed

Clinical Trials on Evaluate the Red Ginseng and Fermented-Red Ginseng Affect to Drug Metabolizing Enzyme and Transporter in Healthy Volunteers

Healthy

Korea, Republic of
AstraZeneca

Completed

Evaluation of Heart Failure Treatment Guided by N-terminal Pro B-type Natriuretic Peptide (NTproBNP) vs Clinical Symptoms and Signs Alone

Heart Failure | Ventricular Dysfunction, Left

Sweden
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Oral Doses of JNJ-54175446 on the Inhibition of Cytochrome P450 CYP3A4, CYP2C9, CYP1A2 and CYP2D6 Activity and the Induction of CYP2B6 and CYP2C19 Activity Using a Multiple Probe Substrate Cocktail in Healthy Subjects

Healthy

Belgium
Da, Yuwei, M.D.

Recruiting

Clinical Prognosis and Progression of Myasthenia Gravis Patients

Myasthenia Gravis

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Suspended

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

B Acute Lymphoblastic Leukemia

United States, Canada
Michael Schneider, DC, PhD
Patient-Centered Outcomes Research Institute

Completed

Study Comparing 3 Different Treatments for Arthritis of the Lower Back (Lumbar Spinal Stenosis)

Lumbar Spinal Stenosis

United States
Hee Young Ju

Recruiting

Treatment of Newly Diagnosed Standard Risk Acute Lymphoblastic Leukemia in Children

Lymphoblastic Leukemia in Children

Korea, Republic of
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Monoclonal Antibody 3F8 and Sargramostim in Treating Patients With Neuroblastoma

Neuroblastoma

United States
University Hospital, Geneva

Unknown

Drug Metabolism and Antidepressant (METADEP)

Depression

Switzerland
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation

Thyroid Gland Follicular Carcinoma | Thyroid Gland Papillary Carcinoma | Thyroid Gland Oncocytic Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Low-Intensity Chemotherapy and Venetoclax in Treating Patients With Relapsed or Refractory B- or T-Cell Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Refractory T Acute Lymphoblastic Leukemia | Recurrent T Acute Lymphoblastic Leukemia

United States

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