Search clinical trials for: Cohort 4: bococizumab 300 mg rHuPH20

Total 107 results

Pfizer
Halozyme Therapeutics

Terminated

Pharmacokinetic and Pharmacodynamic Study of Bococizumab Alone and When Combined With Recombinant Human Hyaluronidase

Healthy | Hypercholesterolemia

Belgium
Nuvamid SA
Medpace, Inc.; Anapharm; LGD

Active, not recruiting

Study of the Safety, Tolerability, and Pharmacokinetics of NUV001 Administered Orally to Healthy Adult Participants

Healthy Volunteers

United States
OrthoTrophix, Inc

Completed

A Study Evaluating the Safety and Efficacy of a Second Course of TPX-100 in Subjects Who Previously Received TPX-100 for Patellar Osteoarthritis Involving Both Knees

Knee Osteoarthritis
Pfizer

Completed

First Safety Study in Humans of a Single Dose of CPG 52364

Healthy Volunteers

United States
Serum Institute of India Pvt. Ltd.
PPD

Completed

Safety Study of Dengushield in Healthy Adults

Dengue | Phase 1

Australia
Bayer

Completed

Continuous Dosing of BAY73-4506 in Patients With Advanced Malignancies

Neoplasm

United States
Jeil Pharmaceutical Co., Ltd.

Completed

Clinical Trial to Investigate the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of JP-1366 Oral Administration in Healthy Male Subjects

Anti-Ulcer Agents

Korea, Republic of
Pfizer

Terminated

Study Evaluating Single Dose Of ILV-095 In Psoriasis Subjects

Plaque Psoriasis

United States, Canada
Gilead Sciences

Completed

Safety, Tolerability, Pharmacokinetics and Antiviral Activity of GS-9669 in Subjects With Chronic Hepatitis C Virus Infection

Hepatitis C

United States, Puerto Rico
Pfizer

Completed

Pharmacokinetic And Pharmacodynamic Study Of A Single-Dose Of PF-04950615 (RN316) In Combination With Atorvastatin

Dyslipidemia | Hypercholesterolemia

United States
MedImmune LLC
Thrombolysis in Myocardial Infarction (TIMI) Study Group

Completed

A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction (REAL-TIMI 63B)

ST Elevation Myocardial Infarction

Netherlands, United Kingdom, Brazil, Spain, Slovakia, Israel, Czechia, Hungary, Poland, Russian Federation
Ixchelsis Limited

Completed

Relative Bioavailability Study of IX-01 Caplet Versus Aqueous Dispersion and Food Effect of the Caplet in Healthy Males (IX-0106 RBA)

Healthy

United States
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI)

Completed

Natural History of HPV Infection in Men: The HIM Study

Human Papillomavirus

United States
Lexicon Pharmaceuticals

Completed

Study of Two Oral Formulations of LX4211 in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Juventas Therapeutics, Inc.

Completed

Study to Evaluate the Safety and Efficacy of JVS-100 Administered to Adults With Critical Limb Ischemia

Critical Limb Ischemia

United States, India
Canadian Heart Research Centre
GlaxoSmithKline

Completed

Avandia™ + Amaryl™ or Avandamet™ Compared With Metformin (AVALANCHE™ Study) (AVALANCHE)

Type 2 Diabetes Mellitus

Canada
Novartis Pharmaceuticals

Completed

First Study of Secukinumab in Pre-filled Syringes in Subjects With Chronic Plaque-type Psoriasis: Response at 12 Weeks (FEATURE)

Moderate to Severe Plaque-type Psoriasis

Germany, United States, Estonia, France, Canada
Evandro Chagas Institute of Clinical Research

Not yet recruiting

Short Benznidazole Regimen for Chronic Phase Chagas Disease Patients (Benlatino)

Chronic Chagas Disease

Brazil
Mothaffar Rimawi

Terminated

CRIZENT: Crizotinib and Sunitinib in Metastatic Breast Cancer (CRIZENT)

Breast Cancer

United States
Lexicon Pharmaceuticals

Completed

Study to Evaluate the Effect of Single Doses of LX4211 and Canagliflozin on Intestinal Glucose Absorption in Healthy Adult Subjects

Healthy Subjects

United States
CymaBay Therapeutics, Inc.

Terminated

Study to Evaluate the Effects of Two Doses of MBX-8025 in Subjects With Primary Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis (PBC)

Germany, United States, Canada, United Kingdom, Poland
Shanghai Henlius Biotech

Active, not recruiting

A Clinical Study to Compare the Efficacy, Safety and Immunogenicity of HLX04 and Bevacizumab Combined XELOX or mFOLFOX6 in the First-line Treatment of mCRC

Metastatic Colorectal Cancer (mCRC)

China
Aziende Chimiche Riunite Angelini Francesco S.p.A
Hippocrates Research

Recruiting

Different Dosage Regimens of Methocarbamol/Paracetamol in Acute Non-specific Low Back Pain. MioPain Study (MioPain)

Low Back Pain

Italy
S.LAB (SOLOWAYS)
NMSI DENTMASTER

Not yet recruiting

A Combination of Ibuprofen With Curcumin Covered With Liquorice Root Supplementation in the Management of Postoperative Dental Pain in Adults (ICLID)

Dental Pain

Russian Federation
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

A Dose-response Study of Tranexamic Acid in Total Hip Arthroplasty (PRADO)

Arthropathy of Hip

France
Daniel Hägi-Pedersen
Copenhagen Trial Unit, Center for Clinical Intervention Research

Completed

PAracetamol and NSAID in Combination: A Randomised, Blinded, Parallel, 4-group Clinical Trial (PANSAID)

Pain, Postoperative

Denmark
University of Colorado, Denver

Active, not recruiting

Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes (IMPROVE-T2D)

Obesity | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes Complications | Type 2 Diabetes Mellitus | Pediatric Obesity | Diabetic Kidney Disease | Diabetic Nephropathies | Weight Loss | Bariatric Surgery Candidate | Adolescent Obesity | Nephropathy

United States
University of Colorado, Denver

Active, not recruiting

Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes Study (Renal-HEIR)

Obesity | Type 2 Diabetes Mellitus | Adolescent Obesity | Nephropathy

United States
University of Colorado, Denver

Completed

Copeptin in Adolescent Participants With Type 1 Diabetes and Early Renal Hemodynamic Function (CASPER)

Diabetes Mellitus, Type 1 | Diabetic Nephropathies | Type 1 Diabetes Mellitus | Diabetes Mellitus Complication | Nephropathy | Autoimmune Diabetes | Juvenile Diabetes

United States
ViiV Healthcare

Recruiting

A Study to Investigate Pharmacokinetics, Safety and Tolerability of Long-Acting Cabotegravir Plus Recombinant Human Hyaluronidase PH20 in Healthy Adult Participants

HIV Infections

United States
Karyopharm Therapeutics Inc

Not yet recruiting

A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia (SENTRY-2)

Myelofibrosis | Moderate Thrombocytopenia
Federal Budgetary Research Institution State Research...

Completed

Study of the Safety, Tolerability, Pharmacokinetics of NIOCH-14 in Volunteers Aged 18-50 Years

Smallpox | Monkeypox | Cowpox | Vaccinia Virus Infection

Russian Federation
Celldex Therapeutics

Terminated

A Study of Glembatumumab Vedotin as Monotherapy or in Combination With Immunotherapies in Patients With Advanced Melanoma

Melanoma

United States
University of Colorado, Denver

Completed

PErfusioN, OxyGen ConsUmptIon and ENergetics in ADPKD (PENGUIN) (PENGUIN)

Polycystic Kidney, Autosomal Dominant | Polycystic Kidney Disease, Adult

United States
Centre Leon Berard
National Cancer Institute, France

Recruiting

Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatment (MOST plus)

Malignant Solid Neoplasms

France
University of Colorado, Denver
Juvenile Diabetes Research Foundation

Completed

Control of Renal Oxygen Consumption, Mitochondrial Dysfunction, and Insulin Resistance (CROCODILE)

Diabetes Mellitus | Diabetes | Diabetes Complications | Type1diabetes | Type 1 Diabetes | Diabetic Kidney Disease | Diabetic Nephropathies | Type 1 Diabetes Mellitus | Autoimmune Diabetes | Diabetes, Autoimmune | Juvenile Diabetes

United States
Hal Chapman
Massachusetts General Hospital; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Recruiting

Collagen-targeted Positron Emission Tomography (PET) Imaging for Assessment of EGCG Effect

Idiopathic Pulmonary Fibrosis

United States
Novartis Pharmaceuticals

Completed

Safety and Efficacy of DNK333 in Atopic Dermatitis Patients

Pruritus in Patients With Atopic Dermatitis

Germany
Merck Sharp & Dohme LLC

Completed

A Notch Signalling Pathway Inhibitor for Patients With Advanced Breast Cancer (0752-014)

Advanced Breast Cancer | Other Solid Tumors
U.S. Army Medical Research and Development Command

Completed

Safety and Tolerability of Antiplaque Chewing Gum in a Gingivitis Population (APCG)

Gingivitis | Plaque

United States
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)

Type 2 Diabetes Mellitus | Diabetic Kidney Disease | Adolescent Obesity | Puberty | Pre Diabetes | Kidney Hypoxia

United States
UCB Biopharma SRL

Withdrawn

A Study to Test the Blood Concentration of 4 Padsevonil Product Variants and the Effect of Food on Padsevonil

Epilepsy | Healthy Participants
Buddhist Tzu Chi General Hospital

Completed

Cyclooxygenase-2 (COX-2) Inhibitor Reduces Serum Prostatic Specific Antigen (PSA) Levels

Benign Prostatic Hyperplasia

Taiwan
GlaxoSmithKline

Completed

Avandamet Bioequivalence Study Brazil - Fed Administration

Diabetes Mellitus, Type 2

Brazil
Morten Lindbaek
Norwegian Institute of Public Health; Sorlandet Hospital HF; Norwegian University...

Completed

Comparing 3 Antibiotic Regimes for Erythema Migrans in General Practice (NorTick_EM)

Lyme Disease | Erythema Migrans | Erythema Chronicum Migrans | Borreliosis | Early Lyme Disease

Norway
Novartis Pharmaceuticals
European and Developing Countries Clinical Trials Partnership (EDCTP); Medicines... and other collaborators

Active, not recruiting

Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria (CALINA)

Plasmodium Falciparum Malaria

Burkina Faso, Congo, The Democratic Republic of the
Lexicon Pharmaceuticals

Completed

Safety and Efficacy of LX4211 With Metformin in Type 2 Diabetes Patients With Inadequate Glycemic Control on Metformin

Type 2 Diabetes Mellitus

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes (MANATEE-T1D)

Cardiovascular Diseases | Type 1 Diabetes | Diabetic Kidney Disease | Endothelial Dysfunction | Insulin Sensitivity

United States
PH Research, S.L.

Completed

Nab-paclitaxel in Combination With Gemcitabine in Fragile Patients With Advanced Pancreatic Cancer (FRAGANCE)

Advanced Pancreatic Cancer

Spain
GlaxoSmithKline

Completed

Effect of Omeprazole and Ritonavir on GSK2336805 Pharmacokinetics in Healthy Adults

Hepatitis C

United States

Search clinical trials for: Cohort 4: bococizumab 300 mg rHuPH20

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