Search clinical trials for: Comparator: simvastatin

Total 2573 results

Cognition Therapeutics

Recruiting

Study to Evaluate the Efficacy and Safety of Oral CT1812 in Participants With Geographic Atrophy (GA) Secondary to Dry Age-Related Macular Degeneration (AMD).

Age-Related Macular Degeneration

United States
Merck Sharp & Dohme LLC

Completed

A Study of the Safety and Efficacy of MK-0773 in Women With Sarcopenia (Loss of Muscle Mass)(MK-0773-005)

Sarcopenia
National Cheng-Kung University Hospital

Completed

Vascular Effects of Ezetimibe/Simvastatin and Simvastatin on Atherosclerosis

Atherosclerosis

Taiwan
Helsinki University Central Hospital
University of Helsinki; Academy of Finland

Completed

Donor Simvastatin Treatment in Organ Transplantation (SIMVA)

Liver Failure | Heart Failure | Respiratory Failure | Kidney Failure | Transplantation

Finland
United States Naval Medical Center, San Diego

Terminated

Low -vs- High-Frequency Repetitive TMS of the Right Dorsolateral Prefrontal Cortex in PTSD

PTSD - Post Traumatic Stress Disorder
Guangzhou JOYO Pharma Co., Ltd

Recruiting

SC1011 Twice Daily vs Placebo in Patients Diagnosed With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

China
AbbVie

Withdrawn

Study to Assess Adverse Events When Subcutaneous Risankizumab Injection is Given to Adult Participants With Psoriasis in Real World Setting

Psoriasis
Clinical Nutrition Research Center, Illinois Institute...

Completed

Acute Effects of Coffee Beverage on Postprandial Inflammation and Oxidative Stress - A Pilot Study (COF1)

Healthy | Overweight | Obese

United States
University of Copenhagen

Unknown

Living With Statins - Interventional Exercise Study (LIFESTAT)

Cardiovascular Disease | Diabetes Mellitus

Denmark
Azienda Ospedaliero Universitaria di Sassari

Unknown

Ezetimibe/Simvastatin Combination in Proteinuric Nephropathy (VICTORY)

Hypercholesterolemia | Chronic Nephropathy

Italy
Merck Sharp & Dohme LLC

Completed

A Single-Dose Study of the Safety, Tolerability, and Pharmacokinetics of Odanacatib (MK0822) in Healthy Volunteers

Osteoporosis
Charite University, Berlin, Germany
German Federal Ministry of Education and Research

Unknown

Trial of Simvastatin in Amnestic Mild Cognitive Impairment (MCI) Patients (SIMaMCI)

Mild Cognitive Impairment

Germany
University of Cologne
Merck Sharp & Dohme LLC

Completed

LDL Receptor Under Ezetimibe and Simvastatin

Healthy Men

Germany
Organon and Co
Merck Sharp & Dohme LLC

Completed

Effects of Ezetimibe With Simvastatin in the Therapy of Adolescents With HeFH (Study P02579)

Hypercholesterolemia
Brasilia Heart Study Group

Completed

Effect of Statin Treatment on Insulin Sensitivity During Myocardial Infarction

Myocardial Infarction

Brazil
Merck Sharp & Dohme LLC

Completed

Concomitant Use of Gardasil (V501) (Human Papillomavirus [Types 6, 11, 16, 18] Recombinant Vaccine) With Combined Diphtheria, Tetanus, Pertussis Vaccine and Meningococcal Conjugate Vaccine in Adolescents (V501-025)

Neoplasms, Glandular and Epithelial | Whooping Cough | Tetanus | Diphtheria | Meningitis
Judit Pich

Completed

Simvastatin Plus Rifaximin in Decompensated Cirrhosis (LIVERHOPE)

Cirrhoses, Liver

Spain, Germany, United Kingdom, Italy, Netherlands, France
Merck Sharp & Dohme LLC

Completed

Hepatitis B Vaccine Booster Study (V232-058)(COMPLETED)

Hepatitis B
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Effects of Exenatide on Insulin Secretion Rates Using a Graded Infusion of Intravenous Glucose (0000-099)(COMPLETED)

Healthy
Heidelberg University

Completed

Effects on NF-κB Activity: High Dose Simvastatin Versus Combination Therapy With Ezetimibe

Inflammation | Type 2 Diabetes

Germany
Organon and Co
Merck Sharp & Dohme LLC; Schering-Plough

Completed

Effects of Vytorin Versus Placebo in Subjects With Primary Hypercholesterolemia (Study P04420)

Hypercholesterolemia
Centre hospitalier de l'Université de Montréal...
Centre de Recherche du Centre Hospitalier de l'Université de Montréal

Terminated

Efficacy Study of SIMVASTATIN to Treat Chronic Rhinosinusitis After Failure of Optimal Treatment

Rhinosinusitis

Canada
University of Sao Paulo

Completed

Antiplatelet and Anti-inflammatory Effects of Statins and Ezetimibe

Stable Angina

Brazil
Stanford University

Recruiting

Accelerated Intermittent Theta-Burst Stimulation (aiTBS) in Treatment-Resistant Depression of Bipolar II Disorder

Treatment Resistant Depression | Bipolar II Disorder, Most Recent Episode Major Depressive | Current Depressive Episode

United States
University of Palermo

Completed

Gluten-related Disorders in Familial Mediterranean Fever Patients

Familial Mediterranean Fever (FMF) | Not-celiac Wheat Sensitivity (NCWS)

Italy
Merck Sharp & Dohme LLC

Completed

Safety and Immunogenicity Study of V710 Lyophilized Formulation (V710-004)

Healthy
Merck Sharp & Dohme LLC

Completed

Broad Spectrum HPV (Human Papillomavirus) Vaccine in 16 to 26 Year Old Women (V505-001)

Cervical Cancer | Vulvar Cancer | Vaginal Cancer | Human Papillomavirus Infection | Genital Warts
UMC Utrecht

Completed

Effects of Ezetimibe on Postprandial Hyperlipidemia and Endothelial Function

Metabolic Syndrome

Netherlands
Gachon University Gil Medical Center

Completed

Vascular and Metabolic Effects of Vytorin vs Simvastatin

Hypercholesterolemia

Korea, Republic of
Federal University of Bahia
Escola Bahiana de Medicina e Saude Publica

Unknown

Pleiotropism of Statin Therapy in High Dose Versus Low Dose Combined With Ezetimibe

Endothelial Function

Brazil
Tulane University
Patient-Centered Outcomes Research Institute

Recruiting

The Allergen Reduction and Child Health Study (ARCHS) (ARCHS)

Asthma in Children

United States
Esther Meijer

Unknown

Wishing to Decrease Aquaresis in ADPKD Patients Treated With a V2Ra; the Effect of Regulating Protein and Salt (WATER)

Polycystic Kidney, Autosomal Dominant | Autosomal Dominant Polycystic Kidney | ADPKD

Netherlands
Merck Sharp & Dohme LLC

Completed

A Study to Test the Safety and Antibody Response of V212 in Healthy Adults (V212-004)(COMPLETED)

Herpes Zoster
Italfarmaco

Completed

Clinical Study to Evaluate the Efficacy and Safety of Givinostat in Ambulant Patients With Becker Muscular Dystrophy

Becker Muscular Dystrophy

Netherlands, Italy
Clinical Nutrition Research Center, Illinois Institute...

Completed

A Pilot Study to Characterize the Bioavailability and Plasma Profile of Potato Polyphenols in Humans (PPT)

Premenopausal Women | Overweight and Obese Women

United States
Merck Sharp & Dohme LLC

Completed

A Study of V503 Given Concomitantly With Menactra™ and Adacel™ in 11 to 15 Year Olds (V503-005)

Human Papillomavirus Infection
Fundación para el Fomento de la Investigación Sanitaria...

Completed

Effects of Simvastatin and Ezetimibe on Cardiovascular Risk Markers in Patients With Dyslipidemia

Dyslipidemia
University of Ioannina

Completed

Comparison of Simvastatin Versus Simvastatin/Ezetimibe on Small Dense Low -Density Lipoprotein (LDL)

Hypercholesterolemia

Greece
Korea University

Withdrawn

Effects on Atherosclerosis Regression of Ezetimibe or Ezetimibe Plus Simvastatin; Evaluated by Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)

Atherosclerosis

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

A Randomized, Double-Blinded Study of Simvastatin 20 mg/Day Versus Vytorin 10/20 in Subjects With Lipid Profiles Not Meeting Current NCEP Guidelines, Following a Low-Carbohydrate Diet (LOCUST)

Hyperlipidemia
Hospital Universitario 12 de Octubre
Merck Sharp & Dohme LLC

Completed

Vytorin on Carotid Intima-media Thickness and Overall Rigidity (VYCTOR)

Cardiovascular Diseases
Organon and Co
Schering-Plough

Completed

Ezetimibe and Simvastatin in Primary Hypercholesterolemia, Diabetes Mellitus Type 2, and Coronary Heart Disease (COMPLETED)

Coronary Disease | Diabetes Mellitus, Type 2 | Hypercholesterolemia
University of Illinois at Chicago

Terminated

Use of Simvastatin for the Prevention of Vasospasm in Aneurysmal Subarachnoid Hemorrhage

Aneurysmal Subarachnoid Hemorrhage | Cerebral Vasospasm

United States
University of Leipzig
Institut für Gesundheits- und Praxismanagement GmbH

Withdrawn

Pioglitazone in Impaired Glucose Tolerance

Glucose Metabolism Disorders

Germany
Clinical Nutrition Research Center, Illinois Institute...

Completed

Bioavailability and Pharmacokinetics of Mango (MG)

Healthy Subjects

United States
GRI Bio, Inc.

Terminated

Trial to Examine the Effect of Two Doses of GRI-0621 in Patients With Chronic Liver Disease (GRI-201)

Chronic Liver Disease

South Africa
Aswan University Hospital

Unknown

Triple Tourniquets With or Without Tranexamic Acid for Reducing Blood Loss at Open Myomectomy (TTT)

Myoma

Egypt
University of Copenhagen
Danisco

Completed

The Effects of L-Arabinose and D-xylose on Intestinal Sucrase Activity in Man (M192)

Insulin Resistance

Denmark
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Carotid Plaque Characteristics by MRI in AIM-HIGH (Carotid MRI Substudy)

Coronary Artery Disease | Atherosclerosis | Carotid Artery Diseases

United States, Canada
Baylor College of Medicine
Merck Sharp & Dohme LLC

Completed

Effects of Ezetimibe, Simvastatin, and Vytorin on Reducing L5 a Subfraction of LDL in Patients With Metabolic Syndrome. (Merck-123)

Metabolic Syndrome

United States

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