Search clinical trials for: Complement C1 Inactivator Proteins

Total 151 results

Pharming Technologies B.V.

Completed

Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema

Hereditary Angioedema | Genetic Disorders | Angioneurotic Edema

Netherlands, Romania
University Hospital, Basel, Switzerland
Pharming Technologies B.V.

Terminated

Conestat Alfa in the Prevention of Severe SARS-CoV-2 Infection in Hospitalized Patients With COVID-19

Coronavirus Infections

Switzerland, Brazil, Mexico
Pharming Technologies B.V.

Terminated

Prevention of Acute Kidney Injury in Patients With NSTEMI (AKI)

Non-ST Elevation Myocardial Infarction (NSTEMI)

Switzerland
Shire

Completed

Safety and Efficacy Study of CINRYZE for Prevention of Angioedema Attacks in Children Ages 6-11 With Hereditary Angioedema

Hereditary Angioedema (HAE)

Israel, Germany, Mexico, United States, Romania
Shire

Completed

Study of C1 Inhibitor (Human) for the Prevention of Angioedema Attacks and Treatment of Breakthrough Attacks in Japanese Subjects With Hereditary Angioedema (HAE)

Hereditary Angioedema (HAE)

Japan
University Hospital, Basel, Switzerland
Swiss National Science Foundation; Pharming Technologies B.V.

Recruiting

Recombinant Human C1 Esterase Inhibitor (Conestat Alfa) in the Prevention of Acute Ischemic Cerebral and Renal Events After Transcatheter Aortic Valve Implantation (PAIR-TAVI)

Acute Renal Injury | Acute Ischemic Stroke

Switzerland
National Taiwan University Hospital

Completed

Anesthetic Management and Remote Reperfusion Injuries

Heart Valve Diseases

Taiwan
Spine Centre of Southern Denmark

Completed

Biomarkers in Early-stage Spondyloarthritis

Ankylosing Spondylitis | Spondyloarthritis
GCS Ramsay Santé pour l'Enseignement et la Recherche

Completed

Evaluation of the Effects of Bradykinin Antagonists on Pulmonary Manifestations of COVID-19 Infections (AntagoBrad-Cov Study). (AntagoBrad)

Covid19

France
Melbourne Health
Sanofi

Withdrawn

Complement Activation in the Lysosomal Storage Disorders (CATALYST)

Lysosomal Storage Diseases | Fabry Disease | Niemann-Pick Disease, Type C | Gaucher Disease

Australia
T. van der Poll
ZonMw: The Netherlands Organisation for Health Research and Development; Prothya...

Terminated

C1-inhibitor in Allergic ASThma Patients (CAST)

Asthma

Netherlands
NMP Medical Research Institute
Aarogyam UK

Completed

Cholesterol Lowering Effect of Cardio-Complement, an Ayurveda Formulation

Hypercholesterolemia

India
University College, London

Unknown

TTP and aHUS in Complicated Pregnancies

Thrombotic Microangiopathies | Thrombotic Thrombocytopenic Purpura | Thrombocytopenia | Pre-Eclampsia | HELLP Syndrome | Stillbirth | Atypical Hemolytic Uremic Syndrome | IUGR

United Kingdom
Francis Corazza

Completed

Evaluation of Interleukine 6 (and Other Cytokines and Inflammatory Markers) in COVID-19 Patients With a Systemic Inflammatory Response Syndrome

COVID-19

Belgium
University of Extremadura

Active, not recruiting

Influence of Co-diagnosis of Chronic Fatigue Syndrome in Patients With Fibromyalgia.

Fibromyalgia | Chronic Fatigue Syndrome | Comorbidities and Coexisting Conditions

Spain
National Institute of Diabetes and Digestive and...

Completed

Kidney Transplant for HIV-Infected Patients in Renal Failure

HIV Infection | Chronic Kidney Failure

United States
Catholic University of Murcia

Completed

Health Parameters in Soccer Players and Sedentary Individuals After Consuming a Synbiotic

Sedentary Behavior | Athlete

Spain
Universitaire Ziekenhuizen KU Leuven

Completed

Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL) (CAPITL)

Reperfusion Injury

Belgium
Assiut University

Unknown

Acute Post Streptococcal Glomerulonephritis

PSGN - Post-Streptococcal Glomerulonephritis
Universitaire Ziekenhuizen KU Leuven

Completed

Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL)

Reperfusion Injury

Belgium
University Hospital Inselspital, Berne
University of Bern

Completed

Characterizing the Immune Response and Neuronal Damage in COVID-19

Covid-19 | SARS-CoV Infection

Switzerland
Regina Elena Cancer Institute
Icahn School of Medicine at Mount Sinai; University of Roma La Sapienza

Unknown

Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-remitting Multiple Sclerosis

Multiple Sclerosis | Relapse

United States, Italy
Northwestern University

Suspended

Study To antagOnize Plasminogen Activator Inhibitor-1 in Severe COVID-19

Covid19

United States
Boehringer Ingelheim

Completed

A Study in Healthy Men to Find the Best Formulation for Once Daily Intake of Nintedanib

Healthy

United Kingdom
Sohag University

Enrolling by invitation

Comparison Between Early-onset and Late-onset Patients With Systemic Lupus Erythematosus.

Systemic Lupus Erythematosus

Egypt
Livzon Pharmaceutical Group Inc.

Active, not recruiting

Immunogenicity and Safety of Sequential Immunization of Recombinant SARS-CoV-2 Fusion Protein Vaccine (COVID-19)

COVID-19 Pandemic

China
Loxo Oncology, Inc.
Eli Lilly and Company

Recruiting

Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL) (BRUIN-MCL-321)

Lymphoma, Mantle-Cell

Canada, United States, China, Australia, Spain, Taiwan, Japan, Belgium, Germany, Denmark, Hungary, Italy, Brazil, Israel, Austria, Czechia, France, Ireland, Korea, Republic of, Netherlands, New Zealand, Poland, Portugal, Russian Federation and more
M.D. Anderson Cancer Center

Recruiting

Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
H. Lee Moffitt Cancer Center and Research Institute
Bayer; Pediatric Cancer Foundation

Completed

Sorafenib and Topotecan in Refractory/Recurrent Pediatric Malignancies

Solid Tumor

United States
The First Hospital of Jilin University

Not yet recruiting

The Diagnostic and Prognostic Value of TAT, PIC, tPAI·C and TM in Sepsis-induced Coagulopathy

Sepsis-induced Coagulopathy
Indonesia University
Singapore General Hospital

Not yet recruiting

Medical Thoracoscopy for Undiagnosed Transudative and Exudative Pleural Effusions

Pleural Effusion

Indonesia
PT Bio Farma
Fakultas Kedokteran Universitas Indonesia; Faculty of Medicine, Diponegoro...

Completed

Safety and Immunogenicity Study of COVID-19 Protein Subunit Recombinant Vaccine Adjuvanted With Alum+CpG 1018

COVID-19

Indonesia
PT Bio Farma
National Institute of Health Research and Development, Ministry of Health... and other collaborators

Completed

Safety and Immunogenicity of SARS-CoV-2 Protein Subunit Recombinant Vaccine

Covid19

Indonesia
University of Southern Denmark
Protac A/S

Recruiting

Effects of Systematic Proprioceptive-tactile Stimulation With Use of the Protac MyFit®

Children | Sensory Processing Disorder

Denmark
Efranat Ltd.

Completed

Safety Study of EF-022 ( Modified Vitamin D Binding Protein Macrophage Activator) in Subjects With Advanced Solid Tumors

Solid Tumors

Israel
Efranat Ltd.

Unknown

Safety Study of EF-022 in Adults With Recurrent Respiratory Papillomatosis (RRP)

Recurrent Respiratory Papillomatosis
International Vaccine Institute
Heidelberg University; International Centre for Diarrhoeal Disease Research... and other collaborators

Active, not recruiting

Mix and Match Heterologous Prime-Boost Study Using Approved COVID-19 Vaccines

Covid19

Madagascar, Mozambique
Stanford University
David Drover, MD

Completed

Pharmacokinetic (PK) and Pharmacodynamic (PD) Modeling of Ampicillin and Gentamicin in Peripartum Patients

Drug Metabolism During Pregnancy

United States
TYK Medicines, Inc

Completed

A Study to Assess the Effect of Food on the Pharmacokinetics of TY-9591 in Healthy Volunteers

Healthy Volunteers

China
Boehringer Ingelheim

Completed

Bioavailability Study of Five Tablet Formulations of Dabigatran Etexilate Compared to Commercial Capsule Formulation in Healthy Male Subjects

Healthy

Japan
Boehringer Ingelheim

Completed

Bioavailability of BIBR 953 ZW in Healthy Subjects

Healthy
Boehringer Ingelheim

Completed

Multiple Oral Doses of BIBR 1048 MS Solution in Healthy Volunteers

Healthy
University of Aarhus
Odense University Hospital; Aarhus University Hospital; Protac A/S; Innovation...

Recruiting

Ball Blankets on Insomnia in Depression in Outpatient Clinics

Insomnia Due to Mental Disorder

Denmark
Ge Junbo

Terminated

Effect of Low-dose Intracoronary Reteplase on Myocardial Infarct Size During Primary Percutaneous Coronary Intervention (RECOVERII)

Acute ST-segment Elevation Myocardial Infarction

China
Huashan Hospital
Shanghai 10th People's Hospital; Shanghai East Hospital; Zhejiang University; The... and other collaborators

Completed

CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase II (CHABLIS-T II)

Stroke

China
Victor Tapson, MD
Bristol-Myers Squibb

Terminated

Standard-dose Apixaban AFtEr Very Low-dose ThromboLYSis for Acute Intermediate-high Risk Acute Pulmonary Embolism (SAFE-LYSE)

Pulmonary Embolism | Right Ventricular Dysfunction | Right Ventricular Failure | Pulmonary Embolism With Acute Cor Pulmonale | Pulmonary Embolism With Pulmonary Infarction | Pulmonary Embolism Subacute Massive

United States
Xu Li
LanZhou University; The Affiliated Nanjing Drum Tower Hospital of Nanjing University... and other collaborators

Not yet recruiting

Nafamostat Mesilate in the Treatment of Severe Infection-associated Coagulopathy (NMSICRCT)

Sepsis | Sepsis-induced Coagulopathy | Nafamostat Mesilate
Ensysce Biosciences
National Institute on Drug Abuse (NIDA)

Completed

Oral Nafamostat in Healthy Volunteers

Pharmacokinetics

United States
Chong Kun Dang Pharmaceutical

Completed

A Study Evaluating the Efficacy and Safety of CKD-314 (Nafabelltan) in Hospitalized Adult Patients Diagnosed With COVID-19 Pneumonia

COVID-19

Russian Federation
Institut Pasteur de Dakar
Ministry of Health, Senegal; Fann Hospital, Senegal; Diamniadio Children Hospital... and other collaborators

Unknown

Efficacy and Safety Evaluation of Treatment Regimens in Adult COVID-19 Patients in Senegal (SEN-CoV-Fadj)

COVID-19

Senegal

Search clinical trials for: Complement C1 Inactivator Proteins

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