Search clinical trials for: Controlled Human Malaria Infection

Total 1448 results

University of Oxford

Completed

VAC063C: A Study to Assess Repeat Blood-stage P. Falciparum Infection

Malaria

United Kingdom
Malaria Vaccine and Drug Development Center
Ministerio de la Protección Social, Colombia.

Completed

Establishment of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers (ChallengeII)

Malaria, Vivax

Colombia
U.S. Army Medical Research and Development Command
United States Agency for International Development (USAID); University of Oxford and other collaborators

Completed

Trial to Evaluate the Safety, Immunogenicity, and Efficacy of Malaria Infection in Malaria Naïve Adults

Malaria

United States
University of Oxford

Completed

A Challenge Study to Assess the Protective Efficacy of Two Malaria Vaccine Candidates (VAC045)

Plasmodium Falciparum Malaria

United Kingdom
U.S. Army Medical Research and Development Command
GlaxoSmithKline; United States Agency for International Development (USAID); Walter... and other collaborators

Completed

Phase 1 Clinical Trial With Controlled Human Malaria Infection (CHMI) to Evaluate the Safety and Efficacy of the Plasmodium Falciparum Vaccine Candidate FMP012 Administered Intramuscularly With AS01B Adjuvant System in Healthy Malaria-Naïve Adults

Malaria

United States
University of Oxford

Completed

A Phase I/IIa Sporozoite Challenge Study to Assess the Efficacy of Candidate Combination Malaria Vaccine Approaches Using the ChAd63 and MVA Vectors Encoding the Antigens ME-TRAP, CS and AMA1

Plasmodium Falciparum Malaria

United Kingdom
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Versus Mefloquine Prophylaxis

Malaria | Plasmodium Falciparum

Netherlands
National University of Singapore
Ministry of Education, Singapore

Completed

Artificial Intelligence Versus Human-controlled Doctor in Virtual Reality Simulation for Sepsis Team Training

Sepsis

Singapore
Centro de Investigação em Saúde de Manhiça
University of California, San Francisco; Barcelona Institute for Global Health and other collaborators

Recruiting

Plasmodium Falciparum Genomic Intelligence in Mozambique (GenMoz)

Malaria | Malaria in Pregnancy | Malaria,Falciparum

Mozambique
NYU Langone Health
National Institute of Allergy and Infectious Diseases (NIAID); New York University and other collaborators

Completed

Effectiveness of Malaria Camps as Part of the Odisha State Malaria Elimination Drive (CSCMi20)

Malaria

India
West China Hospital

Not yet recruiting

Accelerated Recovery for Total Knee Replacement Surgery With Preoperative Intravenous Iron Combined With Human Erythropoietin for Rapid Hematopoietic Mobilization to Prevent Postoperative Anemia (Hematoboost)

Total Knee Arthroplasty

China
University of Oxford
Kinshasa School of Public Health; Wellcome Sanger Institute

Completed

Monitoring Pregnant Women for Antimalarial Drug Resistance (MIRANDA)

Malaria

Congo, The Democratic Republic of the
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Moi University

Completed

Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector

Fever | Malaria

Kenya
Koç University

Recruiting

A Human-Centered SH+ Trial for Earthquake Survivors

Grief Disorder, Prolonged

Turkey
Ottawa Hospital Research Institute

Unknown

Evaluating the Ottawa Malaria Decision Aid (OMDA)

Malaria

Canada
Dragonboat Biopharmaceutical Company Limited
Shanghai East Hospital

Unknown

Phase I Clinical Trial of Human Anti-PD-L1 Antibody Injection (LDP) in Patients With Advanced Malignant Tumors

Advanced Tumors

China
Leiden University Medical Center

Not yet recruiting

Durability of Protection After Single Immunisation With GA2 Sporozoites (CoGA-Rechallenge)

Malaria,Falciparum
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; Groupe de Recherche Action en Sante

Recruiting

Understanding and Maximizing the Community Impact of Antimalarial Treatment (INDIE-SMC) (INDIE-SMC)

Malaria | Malaria,Falciparum

Burkina Faso
Karolinska University Hospital
Muhimbili University of Health and Allied Sciences

Completed

Rapid Diagnostic Testing and Artemisinin-Based Combination Therapy for Uncomplicated Malaria by Community Health Workers

Uncomplicated Plasmodium Falciparum Malaria

Tanzania
Malaria Consortium
London School of Hygiene and Tropical Medicine; Northwestern University; Nigerian...

Active, not recruiting

Perennial Malaria Chemoprevention (PMC) Effect Study (PMCEffect)

Malaria

Nigeria
Dragonboat Biopharmaceutical Company Limited
West China Hospital

Recruiting

An Exploratory Clinical Study of LDP Combined With CDP1 in Patients With Advanced Malignant Tumor

Advanced Malignant Tumor

China
University of Bamako
United States Agency for International Development (USAID); Centers for Disease...

Completed

Evaluation of Seasonal Malaria Chemoprevention in Kita

Anemia | Malaria
Dragonboat Biopharmaceutical Company Limited
Fudan University

Recruiting

the Efficacy and Safety of LDP in Patients With Urinary and Male Genital Tumors

Bladder Cancer | Renal Carcinoma | Advanced Penile Carcinoma

China
Synermore Biologics (Suzhou) Co., Ltd.

Completed

A Bridging Study of the SYN023 on Healthy Adult Subjects

Vaccine Reaction | Rabies Human | Immunisation Reaction | Zoonotic Disease | Communicable Disease Transmission

China
GlaxoSmithKline

Completed

Efficacy of RTS,S/AS01 Vaccine Against Episodes of Malaria Due to P. Falciparum Infection in Children.

Malaria

Kenya, Tanzania
The First Hospital of Jilin University

Completed

Phase Ib of Recombinant Human Albumin Injection

Ascites

China
Radboud University Medical Center
Bill and Melinda Gates Foundation

Completed

Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous Infection (BMGF2b)

Malaria

Netherlands
Ghana Health Services
London School of Hygiene and Tropical Medicine

Completed

The Role of Rapid Diagnostic Tests for Malaria for Targeting of ACTs at Community Level (GhanaCommRDT)

Malaria

Ghana
Julphar Gulf Pharmaceutical Industries
Profil Institut für Stoffwechselforschung GmbH

Completed

Pharmacokinetic (PK) Bioequivalence and Pharmacodynamics (PD) of Julphar Insulin N and Huminsulin® Basal

Diabetes Mellitus

Germany
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Moi University

Completed

Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector (Aim 2)

Fever | Malaria

Kenya
Shanxi Kangbao Biological Product Co., Ltd.
Institute of Pathogen Biology, Chinese Academy of Medical Sciences

Recruiting

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LP-98 Injection in Healthy Subjects

Hiv

China
Radboud University Medical Center
The PATH Malaria Vaccine Initiative (MVI); QIMR Berghofer Medical Research...

Completed

Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2 (CHMI-trans2)

Transmission | Malaria,Falciparum | Controlled Human Malaria Infection | Gametocytes

Netherlands
Swiss Tropical & Public Health Institute
Makerere University; Kinshasa School of Public Health; Clinton Health Access... and other collaborators

Completed

Monitoring of Molecular Markers of Artemisinin Resistance Through Repeated Cross-sectional Assessments in DR Congo, Nigeria and Uganda (Caramal DRM)

Severe Malaria

Congo, The Democratic Republic of the, Nigeria, Uganda
The First Hospital of Jilin University

Completed

Safety and Tolerance Study of Recombinant Human Albumin Injection in Healthy Subjects.

Ascites

China
Radboud University Medical Center

Completed

Study to Investigate the Induction of an Protective Immune Response to Malaria

Falciparum Malaria

Netherlands
Brown University

Recruiting

Intranasal Insulin for Treatment of Alcohol Use Disorder (ITA)

Alcohol Use Disorder

United States
London School of Hygiene and Tropical Medicine
DBL -Institute for Health Research and Development

Completed

Different Approaches for Delivery of IPT in Pregnancy in Burkina Faso

Birth Weight | Anaemia | Malaria Parasitaemia

Burkina Faso
Duke University
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics (INTREPiD)

Pregnancy | Preterm Birth | Gestational Age and Weight Conditions | Malaria in Pregnancy | Stillbirth | Low Birthweight | Malaria,Falciparum | Neonatal Health | Malaria in Childbirth

Congo, The Democratic Republic of the, Kenya
Vanderbilt University Medical Center
Baxter Healthcare Corporation

Completed

Descriptive Study of Cardiac Output During Rehydration With Recombinant Human Hyaluronidase in Pediatrics (Hylenex)

Dehydration | Pediatrics | Cardiac Output

United States
Radboud University Medical Center
Bill and Melinda Gates Foundation

Completed

Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under Chemoprophylaxis (BMGF1)

Malaria

Netherlands
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; University of California, San Francisco; Medical... and other collaborators

Recruiting

P. Falciparum Infection Dynamics and Transmission to Inform Elimination (INDIE-1b)

Malaria

Gambia
Angde Biotech Pharmaceutical Co., Ltd.

Recruiting

A Study of PEG-EPO Injection (CHO Cells) for Maintenance Therapy of Patients With Renal Anemia .

Renal Anemia

China
U.S. Army Medical Research and Development Command

Completed

Weekly Dosing of Malarone ® for Prevention of Malaria (MALWEEK)

Malaria

United States
First Affiliated Hospital Xi'an Jiaotong University
Shenyang Pharmaceutical University

Unknown

High-dose Use of rhTPO in CIT Patients (HUrhTPOCITP)

Thrombocytopenia

China
Kintampo Health Research Centre, Ghana
London School of Hygiene and Tropical Medicine

Completed

Restricting the Use of Artesunate Plus Amodiaquine Combination Therapy to Malaria Cases Confirmed by a Dipstick Test: A Cluster Randomised Control Trial (RDT-ACT)

Malaria

Ghana
Jiangsu Topcel-KH Pharmaceutical Co., Ltd.
Changhai Hospital

Not yet recruiting

A Study of Human TH-SC01 Cell Injection for Treating Perianal Fistulas in Patients With Crohn's Disease

Crohn's Disease | Perianal Fistula
Nycomed

Completed

TachoSil Versus Standard Surgical Treatment for Air Leakage in Pulmonary Lobectomy (TC-021-IM)

Intraoperative Complications | Pulmonary Diseases

Denmark
Shanghai Gebaide Biotechnology Co., Ltd.

Unknown

A Phase III Trial of Recombinant Human Apo-2 Ligand for Injection

Non-small-cell Lung Cancer (NSCLC) Stage IV

China
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Comparative Clinical Trial to Evaluate Bioequivalency and Safety of Monoclonal Antibody Injection and Adalimumab in Chinese Healthy Volunteers

Healthy
Zensun Sci. & Tech. Co., Ltd.

Recruiting

Evaluation of the Effect of Injectable Neucardin on Cardiac Function and Reversal Ventricular Remodeling in Patients With Chronic Systolic Heart Failure

Chronic Systolic Heart Failure

China

Search clinical trials for: Controlled Human Malaria Infection

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