Search clinical trials for: DE-114 ophthalmic solution

Total 1603 results

Intuor Technologies, Inc.

Unknown

CATS Tonometer IOP Reduction Latanoprost Verses Timolol

Glaucoma; Drugs

United States
Dompé Farmaceutici S.p.A

Completed

A 2 Weeks Study to Evaluate Tolerability, Safety, Permanence on the Ocular Surface and Efficacy of Two Concentrations of Lubricin Eye Drops Versus Sodium Hyaluronate 0.18% Eye Drops in Patients With Ocular Discomfort Following Refractive Surgery

Ocular Discomfort

Italy
Azienda Ospedaliero, Universitaria Meyer

Completed

Safety and Efficacy of Propranolol Eye Drops in Treating Retinopathy of Premature (DROP-PROP)

Retinopathy of Prematurity

Italy
Genovate Biotechnology Co., Ltd.,
Allergan Medical

Unknown

Combigan Ophthalmic Solution(Brimonidine 0.2% and Timolol 0.5%)With Latanoprost Compared With Latanoprost Monotherapy

Glaucoma

Taiwan
Maanasa Indaram, MD

Enrolling by invitation

Dextenza for Corneal Crosslinking

Keratoconus

United States
ImmunoGen, Inc.

Not yet recruiting

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Recurrent Ovarian Cancer | Folate Receptor-Alpha Positive

United States, Spain, Australia, Belgium, Canada, France, Ireland, Italy
Shanghai Eye Disease Prevention and Treatment Center
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Unknown

Atropine for Children and Adolescent Myopia Progression Study

Myopia

China
Andover Research Eye Institute

Completed

A Study Comparing the Efficacy of Pataday® Once Daily Relief Extra Strength to Claritin® Tablets 24-Hour in Subjects With Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Chulalongkorn University

Completed

Topical Bevacizumab for Preventing Recurrent Pterygium

Pterygium | Bevacizumab | VEGF | Anti-VEGF

Thailand
Peregrine Eye and Laser Institute

Completed

Postoperative Safety Outcomes of Intraoperative Intracameral Preservative-Free Moxifloxacin Versus Levofloxacin

Cataract Senile | Endophthalmitis | Antibiotic Side Effect | Safety Issues

Philippines
State University of New York College of Optometry

Completed

The Effects of Low Dose Atropine on Choroidal Thickness

Myopia

United States
University Hospital, Basel, Switzerland

Completed

Vitamin D 24'000 IU for Oral Intermittent Supplementation (DO-IT)

Vitamin D Deficiency

Switzerland
Shahid Beheshti University of Medical Sciences

Recruiting

Pharmacological Treatment of Presbyopia

Near Vision

Iran, Islamic Republic of
daphne brockington

Unknown

Continuous Alloreactive T Cell Depletion and Regulatory T Cell Expansion for the Treatment of Steroid-refractory or Dependent Chronic GVHD (CARE)

Chronic GVHD After HCT for Cancer or Immune Disease

Canada
Azienda Ospedaliero, Universitaria Meyer

Completed

Safety and Efficacy of Propranolol 0.2% Eye Drops in Treating Retinopathy of Premature: A Pilot Study (DROP-ROP-0.2%)

Retinopathy of Prematurity

Italy
University Hospital, Basel, Switzerland

Completed

Effect of Alphagan and Xalatan Eye Drops on Corneal Temperature

Primary Vascular Dysregulation

Switzerland
Azidus Brasil

Unknown

Effectiveness Comparison Between the Drugs TOBRACORT® and TOBRADEX® in Reducing the Signs and Symptoms of Acute Bacterial Conjunctivitis

Acute Bacterial Conjunctivitis

Brazil
Pfizer

Completed

Safety and Efficacy of PF-04217329 in Patients With Glaucoma or Elevated Eye Pressure.

Ocular Hypertension | Primary Open-Angle Glaucoma

United States
Allergan

Completed

A Study to Compare a New Eye Drop Formulation With Systane® Gel Drops and Genteal® Lubricant Gel Drops for Moderate to Severe Dry Eye Relief

Dry Eye Syndromes

United States
Glaukos Corporation

Completed

Evaluation of the iStent Versus Two Ocular Hypotensive Agents in Patients With Primary Open-angle Glaucoma (POAG) (SL)

Glaucoma | Glaucoma, Open-Angle | Eye Diseases

Spain, France, Austria, Italy, Armenia, Germany, Greece, Poland, United Kingdom
Alcon Research

Completed

A Study to Evaluate the Clinical Efficacy and Safety of Tobradex® ST Compared to Azasite® in the Treatment of Subjects With Moderate to Severe Chronic Blepharitis

Blepharitis

United States
Allergan

Completed

Evaluate the Safety and Efficacy of a New Artificial Tear for Use After LASIK Surgery

Dry Eye Syndrome

United States
Hotel Dieu Hospital
Sunnybrook Health Sciences Centre

Unknown

IntraVitreal Triamcinolone Acetonide: Preventing Raised Eye-pressure by Tracking Elevations After Topical Steroids (IVTA:PRE-TREAT)

Ocular Hypertension | Vitreoretinal Disease

Canada
Erasmus Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

MAD Trial: Myopia Atropine Dose (MAD)

Progressive Myopia

Netherlands
Alcon Research

Completed

A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
National Cancer Institute (NCI)

Terminated

Pilot Study of Denosumab in BRCA1/2 Mutation Carriers Scheduled for Risk-Reducing Salpingo-Oophorectomy

Ovarian Carcinoma

United States, Israel
Italian Society of Nephrology
European Commission; Memorial University of Newfoundland

Terminated

Bicarbonate v Saline to Prevent Contrast Nephropathy

Kidney Failure, Acute | Contrast Media

Italy
Medical University of Vienna
Croma-Pharma GmbH

Completed

Assessment of Safety and Tolerability of Chitosan-N-acetylcysteine Eye Drops in Subjects While Wearing Contact Lenses and Before Insertion of Contact Lenses

Dry Eye Syndrome

Austria
Synairgen Research Ltd.

Completed

A Study to Test a Potential New Treatment for COPD Patients Suffering From the Common Cold or Influenza

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Mahidol University

Completed

Topical Timolol for Superficial Infantile Hemangioma

Hemangioma

Thailand
CHU de Reims

Unknown

Evaluation of a Protocol of Pupil Dilation Before Laser-assisted Cataract Surgery (MYFLACS)

Cataract Surgery

France
Inotek Pharmaceuticals Corporation

Completed

A Phase II Study to Evaluate the Additivity of Trabodenoson to Latanoprost in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma

Ocular Hypertension (OHT) | Primary Open-Angle Glaucoma (POAG)

United States
Alcon Research

Completed

A 6-Week Safety and Efficacy Study of Travatan Compared to Xalcom in Subjects With Open-Angle Glaucoma(OAG) or Ocular Hypertension(OHT)

Ocular Hypertension | Glaucoma, Open-Angle

United States
Bayer

Completed

Assessment of Strategies for the Management of Flu-like Symptoms in MS Patients Commencing Treatment With Betaferon (INFLUENCE) (INFLUENCE)

Multiple Sclerosis

Poland
Bayer

Completed

Open Label Study to Evaluate Effect, Safety and Tolerability of Betaferon Standard Dose of 250µg in Patients of Chinese Origin With Multiple Sclerosis

Multiple Sclerosis

China
Yonsei University

Recruiting

A Clinical Trial to Evaluate the Clinical Efficacy of Cyclosporine 0.1% (Ikervis®) for Moderate to Severe Dry Eye Patients. (IKE-03-SWITCHING)

Moderate to Severe Dry Eye

Korea, Republic of
Toyos Clinic
Sun Pharmaceutical Industries Limited

Recruiting

Clinical Efficacy of Two Topical Dry Eye Drops for Central Corneal Stain Clearing Over 90 Days

Dry Eye

United States
Oculis

Completed

Efficacy and Safety of Dexamethasone Nanoparticles Eye Drops in Diabetic Macular Edema

Diabetic Macular Edema

Denmark
CHA University
Hanlim Pharm. Co., Ltd.

Unknown

Comparison of Efficacy and Ocular Surface Disease Assessment Between BRIDIN-T Eye Drops 0.15% and ALPHAGAN-P Eye Drops 0.15% in Glaucoma or Ocular Hypertensive Patients : Phase 4, Parallel Group Design, Investigator-blind, Active-control, Randomized, Multi-center Trial

Glaucoma | Ocular Hypertensive

Korea, Republic of
Glostrup University Hospital, Copenhagen

Completed

Pupillary Response After Glaucoma Medication (pupil)

Drug Effect (Glaucoma Drugs)

Denmark
Wenzhou Medical University

Completed

Efficacy of Nonsteroidal Anti-inflammatory Drugs in Treatment of Moderate and Severe Dry Eye Disease

Moderate to Severe Dry Eye Syndrome

China
Bayer

Terminated

Regorafenib Eye Drops: Investigation of Efficacy and Safety in Neovascular Age Related Macular Degeneration (DREAM)

Macular Degeneration

Hong Kong, Korea, Republic of, United States, Canada, Switzerland, Spain, Japan, Italy, Czech Republic, Australia, Austria, Slovakia, Germany, Hungary, Israel, Chile, France, Colombia
Wright State University

Recruiting

Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure (RAPID PRESS)

Respiratory Failure | Intubation Complication | Anesthesia Intubation Complication | Hypotension and Shock | Hypotension on Induction

United States
Klinički Bolnički Centar Zagreb
University of Zagreb

Recruiting

Switching From the Preserved to the Preservative - Free Latanoprost - Timolol FC in Glaucoma Patients With OSD

Ocular Hypertension | Primary Open-angle Glaucoma

Croatia
Alcon Research

Completed

Nepafenac 0.1% Eye Drops, Suspension Compared to Ketorolac Trometamol 0.5% Eye Drops, Solution and Placebo

Cataracts

France
Alcon Research

Completed

A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma
Baxalta now part of Shire
Takeda Development Center Americas, Inc.

Recruiting

A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)

Von Willebrand Disease

United States, Belgium, Spain, Italy, Turkey, Germany, Austria, France, Czechia, Russian Federation, Ukraine, United Kingdom, Netherlands
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study of Glaucoma or Ocular Hypertension in Patients Within the United States

Ocular Hypertension | Glaucoma

United States
ForSight Vision5, Inc.

Completed

Dose-Ranging Study of the Bimatoprost Ocular Insert

Ocular Hypertension | Primary Open-Angle Glaucoma

United States
Alcon Research

Completed

Fluorophotometry Evaluation of Lubricant Eye Drops

Healthy

United States

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