Search clinical trials for: Debio 1450

Total 6662 results

Cairo University

Not yet recruiting

Effect of Gradually Increasing Force Magnitude on the Rate of Canine Retraction Randomized Controlled Trial

Canine Retraction

Egypt
SecuraBio

Completed

A Long-term, Continued Treatment and Follow-up Study in Participants With Hematologic Malignancies Treated With Duvelisib (IPI-145)

Hematologic Malignancy

United States, Italy
Purdue University
National Institute on Deafness and Other Communication Disorders (NIDCD)

Completed

Effectiveness of Expiratory Muscle Strength Training for Improving Communication in ALS

Amyotrophic Lateral Sclerosis

United States
Amicus Therapeutics

Completed

Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Migalastat in Pediatric Subjects (Aged 12 to <18 Years)

Fabry Disease

United Kingdom, United States
EMD Serono

Terminated

Long-term Safety and Tolerability of Atacicept (Long-term Follow-Up of Participant Who Participated in ADDRESS II)

Lupus Erythematosus, Systemic

United States, Korea, Republic of, Bulgaria, Argentina, Mexico, Italy, Spain, Philippines, Germany, Czechia, Chile, Poland, Peru, United Kingdom, South Africa, Brazil, Russian Federation
Kevin Winthrop
Patient-Centered Outcomes Research Institute; Medical University of South Carolina and other collaborators

Recruiting

Comparison of Two- Versus Three-antibiotic Therapy for Pulmonary Mycobacterium Avium Complex Disease (MAC2v3)

Mycobacterium Avium Complex | Nontuberculous Mycobacterium Infection

United States, Canada
Kilimanjaro Clinical Research Institute
European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Evaluation of Pharmacokinetics and Safety Tolerability of Higher Doses of Rifampic (HighRif C)

Clinical Trial

Tanzania
Insmed Incorporated

Completed

A Study to Assess Pharmacokinetics (PK) of Brensocatib Alone and With Multiple Doses of Rifampin or Esomeprozole in Healthy Participants

Healthy Volunteers

United States
University of California, San Francisco

Completed

Drug-Drug Interaction Between Rifampin and Fluvastatin

Drug-drug Interaction

United States
Pfizer

Completed

Drug Interaction Study Evaluating the Effect of Rifampin on PK and Safety of PF 04965842.

Healthy

Belgium
Shanghai Public Health Clinical Center
Yunnan Provincial Infectious Disease Hospital; The Second Hospital of Nanjing...

Completed

Optimization of Antiretroviral Therapy (OAT)

HIV Infections

China
Celgene

Completed

Influence of Rifampin on the Pharmacokinetics of Romidepsin in Patients With Advanced Cancer

Hematologic Malignancy | Malignant Lymphoma

United States, United Kingdom
McMaster University
The Physicians' Services Incorporated Foundation

Completed

Efficacy of Metronidazole Versus Metronidazole and Rifampin in CDAD Treatment

Antibiotic-Associated Diarrhea | Clostridium Enterocolitis | Pseudomembranous Colitis | Pseudomembranous Enterocolitis | Pseudomembranous Enteritis

Canada
ViiV Healthcare
GlaxoSmithKline

Terminated

Dose-finding Study of GSK2248761 in Antiretroviral Therapy-Naive Subjects (SIGNET) (SIGNET)

Infection, Human Immunodeficiency Virus

Spain, France, Germany
The University of Texas Health Science Center at...
Pfizer

Completed

Use of Azithromycin and Rifabutin Administered 3 Times Weekly for the Treatment of M. Avium Complex (MAC) Lung Disease

Mycobacterium Avium Complex

United States
Centre for the AIDS Programme of Research in South...

Completed

Trial to Assess the Impact of PrEP to Tenofovir Gel on the Efficacy of Tenofovir-containing ART on Viral Suppression (TOAST)

Antiretroviral Treatment Outcomes

South Africa
Pfizer

Withdrawn

Effect Of Rifampin On Pharmacokinetics Of Sitaxsentan

Pulmonary Arterial Hypertension
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Gilead Sciences

Completed

Efficacy and Safety of 2 Raltegravir Doses in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis

HIV Infections | Tuberculosis

France, Brazil
Centers for Disease Control and Prevention
US Department of Veterans Affairs

Completed

TBTC Study 23C: Pharmacokinetics of Intermittent Rifabutin and Isoniazid With Daily Efavirenz

HIV Infections | Tuberculosis

United States, Canada
Tibotec BVBA

Completed

VX-950-TiDP24-C134: Drug-drug Interaction Trial Between Combination of Efavirenz and Tenofovir Disoproxil Fumarate and Different Dosages of Telaprevir on Healthy Volunteer

Hepatitis C | HIV | HCV | AIDS
Clinical Trial Agency of HIV Study Group

Completed

Once a Day (QD) - Twice a Day (BID) Clinical Trial: Didanosine, Lamivudine and Efavirenz Versus Zidovudine, Lamivudine and Efavirenz in the Starting Treatment of HIV

HIV Infections

Spain
Triangle Pharmaceuticals

Unknown

A Comparison of Emtricitabine and Stavudine Used With Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs

HIV Infections

United States, Puerto Rico, Canada, Argentina, Chile, Mexico
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Study to Evaluate Drug-Drug Interaction of TQ05105 Tablets

Myelofibrosis

China
Boehringer Ingelheim

Recruiting

A Study in People With Advanced Cancer to Test Whether the Amount of BI 907828 in the Blood is Influenced by Taking an OATP Inhibitor or a CYP3 Inhibitor

Solid Tumors

Spain, Belgium
KBP Biosciences
Covance

Completed

Drug to Drug Interaction Study of KBP-5074 in Healthy Subjects

Healthy | Drug Drug Interaction

United States
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

A Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of Jaktinib in Healthy Volunteers

Healthy Volunteers

China
Abbisko Therapeutics Co, Ltd

Enrolling by invitation

A Clinical Trial to Evaluate the Effect of Itraconazole and Rifampicin on ABSK021

Healthy Subjects

China
Jiangsu Aosaikang Pharmaceutical Co., Ltd.

Completed

Drug-drug Interaction Study Beteewn ASK120067 and Rifampicin or Itraconazole

Locally Advanced or Metastatic NSCLC

China
National Institute of Allergy and Infectious Diseases...

Completed

A Phase II/III Trial of Rifampin, Ciprofloxacin, Clofazimine, Ethambutol, and Amikacin in the Treatment of Disseminated Mycobacterium Avium Infection in HIV-Infected Individuals.

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Impact Therapeutics, Inc.

Completed

IMP4297 DDI (Drug-Drug Interaction)Trial in Healthy Male Volunteers

Solid Tumor

China
Pfizer
Medivation, Inc.

Completed

A Study to Evaluate the Effect of Itraconazole and Rifampin on the Pharmacokinetics of Talazoparib in Patients With Advanced Solid Tumors

Advanced Solid Tumors

Russian Federation, Hungary, Moldova, Republic of, Poland
Janssen Research & Development, LLC

Completed

A Study to Assess the Effects of Itraconazole and Rifampin on Lazertinib in Healthy Adult Participants

Healthy

United States
Genentech, Inc.

Completed

A Study to Investigate the Effect of Itraconazole and Rifampin on Pharmacokinetics (PK) of Vemurafenib at Steady State

Metastatic Melanoma, BRAF V600 Mutation Positive

Korea, Republic of, Russian Federation, Israel, United States
University of Cape Town
Desmond Tutu HIV Centre; Wits Reproductive Health and HIV Institute

Terminated

Clinical Evaluation of Adjusted Doses of Darunavir/Ritonavir With Rifampicin in HIV-infected Volunteers (Darifi)

HIV Infections

South Africa
PTC Therapeutics

Completed

Evaluate Effects of Multiple Doses of Rifampin and Clarithromycin on the Single Dose Pharmacokinetics of Deflazacort

Healthy Volunteers

United States
IRCCS Policlinico S. Matteo
Oslo University Hospital; University of the Basque Country (UPV/EHU); The Hospital...

Completed

AMSA and Amiodarone Study in Cardiac Arrest (MOSAIC)

Out-Of-Hospital Cardiac Arrest

Italy, Norway, Spain
University of Leipzig
Abbott Medical Devices; Leipzig Heart Institute GmbH; Zentrum für Klinische Studien...

Completed

Catheter Ablation Versus Amiodarone for Therapy of Premature Ventricular Contractions in Patients With Structural Heart Disease (CAT-PVC)

Heart Diseases | Cardiomyopathies | Ventricular Premature Complexes

Germany
Texas Cardiac Arrhythmia Research Foundation
Stanford University; The University of Texas Medical Branch, Galveston; University... and other collaborators

Completed

Ablation vs Amiodarone for Treatment of AFib in Patients With CHF and an ICD

Heart Failure

United States
Prism Pharmaceuticals

Completed

Relative Bioavailability of PM101 IV and Cordarone IV

Healthy

Canada
Fundación Cardioinfantil Instituto de Cardiología
Instituto de Corazón de Bucaramanga

Unknown

A Trial Testing Amiodarone in Chagas Cardiomiopathy (ATTACH)

Chagas Cardiomyopathy

Colombia
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)

Heart Diseases | Cardiovascular Diseases | Heart Failure | Arrhythmia | Death, Sudden, Cardiac | Heart Failure, Congestive
Rambam Health Care Campus

Unknown

Treatment of Postoperative Atrial Fibrillation - Comparison of Amiodarone and Placebo.

Atrial Fibrillation
Ottawa Hospital Research Institute
Heart and Stroke Foundation of Ontario

Completed

Atrial Fibrillation Without Hemodynamic Instability in the Intensive Care Unit (AFIB)

Atrial Fibrillation
Rigshospitalet, Denmark

Completed

The Effect of Short Term Amiodarone Treatment After Catheter Ablation for Atrial Fibrillation (AMIO-CAT)

Atrial Fibrillation

Denmark
Advanz Pharma

Withdrawn

A Study Comparing Vernakalant Therapy to Amiodarone Therapy in Acute Management of Recent Onset Atrial Fibrillation (AF) (MK-6621-055)

Atrial Fibrillation
University Medical Center Groningen
Netherlands Heart Foundation

Completed

Continuous Versus Episodic Amiodarone Treatment for the Prevention of Permanent Atrial Fibrillation

Persistant Atrial Fibrillation

Netherlands
University of Calgary
Wyeth is now a wholly owned subsidiary of Pfizer; Heart and Stroke Foundation...

Completed

Amiodarone to Prevent Post-Operative Arrhythmias

Atrial Fibrillation

Canada
Shouyao Holdings (Beijing) Co. LTD

Not yet recruiting

A Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of SY-5007 in Healthy Subjects

Healthy Subjects

China
Basilea Pharmaceutica

Completed

A Drug-Drug Interaction Study of CYP3A4 Inhibition and Pan-CYP Induction on APX001

Fungal Infection

Netherlands
Celgene

Terminated

A Safety and Efficacy Study of CC-90011 in Participants With Relapsed and/or Refractory Solid Tumors and Non-Hodgkin's Lymphomas

Neoplasms | Lymphoma, Non-Hodgkin

France, Italy, Japan, Spain, United Kingdom

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