Search clinical trials for: Debio 1347

Total 141 results

Debiopharm International SA
Caris Life Sciences; Optimal Research (Just In Time sites)

Terminated

Basket Trial in Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3- (FUZE Clinical Trial)

Solid Tumor

United States, Spain, Austria, Czechia, Denmark, Russian Federation, United Kingdom, Greece, Norway, Korea, Republic of, France, Taiwan, Netherlands, Bulgaria, Finland, Ukraine, Australia, Brazil, Croatia, Philippines, Poland, Rom... and more
ModernaTX, Inc.

Active, not recruiting

A Study of Modified mRNA Vaccines in Healthy Adults

Cytomegalovirus | SARS-CoV-2 | Seasonal Influenza | Respiratory Syncytial Virus

United States
Cephalon
H. Lundbeck A/S; The Parkinson Study Group

Terminated

Safety and Efficacy Study of CEP-1347 in the Treatment of Parkinson's Disease

Parkinson Disease

United States, Canada, Puerto Rico
Memorial Sloan Kettering Cancer Center
Debiopharm International SA

Completed

A Study of Debio 1347 Plus Fulvestrant in Patients With Metastatic Breast Cancer

Breast Cancer

United States
Debiopharm International SA

Completed

Study of Debio 0932 in Patients With Advanced Solid Tumours or Lymphoma

Neoplasms | Lymphoma | Cancer | Solid Tumors

France
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
Merck KGaA, Darmstadt, Germany

Completed

PK Study of Xevinapant (Debio 1143) in Healthy East Asian Participants

Healthy

United Kingdom
Debiopharm International SA

Recruiting

A Study to Evaluate Safety and Preliminary Anti-tumor Activity of Debio 0123 as Monotherapy in Adult Participants With Advanced Solid Tumors

Advanced Solid Tumors

Spain, United States, Switzerland
Debiopharm International SA

Completed

Dose Escalation Study of Safety and Tolerability of AT-406 in Patients With Advanced Solid Tumors and Lymphomas

Lymphoma | Cancer | Solid Tumors | Malignancy

United States
Debiopharm International SA

Not yet recruiting

A Dose Finding Study of Debio 4228 in Participants With Locally Advanced/Metastatic Prostate Cancer

Prostate Cancer
Allysta Pharmaceutical

Completed

H-1337 Ophthalmic Solution Phase 1/2

Glaucoma, Open-Angle

United States
Debiopharm International SA

Completed

Long Term Follow-up Study to Assess Durability of Sustained Virologic Response in Alisporivir-treated Hepatitis C Patients

Hepatitis C

Romania, Italy, Belgium, Germany, Hungary, Taiwan, Spain, Australia, Hong Kong, Thailand, France, United States, United Kingdom, Turkey, Argentina, Russian Federation, India, Korea, Republic of, Vietnam, Poland, Mexico, Canada
Debiopharm International SA

Completed

Study of Debio 1450 for Bacterial Skin Infections

Bacterial Infections

United States
Debiopharm International SA

Completed

A Multiple Dose Study of Debio 1450 [Intravenous (IV) and Oral] in Healthy Volunteers

Bacterial Infections

United States
Debiopharm International SA

Completed

Mass Balance Recovery and Metabolic Profile of 14C Debio 1450 Following Single Oral and Intravenous Doses in Healthy Male Subjects

Healthy

United Kingdom
Debiopharm International SA

Completed

A Single Dose Study of Debio 1450 in Healthy Subjects

Bacterial Infections

United States
Christian von Buchwald
Bispebjerg Hospital

Recruiting

NO Measurements in Screening for Asthma and OSA, in Patients With CRSwNP

Asthma | Obstructive Sleep Apnea | Chronic Rhinosinusitis (Diagnosis) | Nasal Polyps | Inflammatory Disease | Airway Disease | Concomitant Disease

Denmark
Debiopharm International SA

Completed

Drug Penetration Into Bone After Repeated Oral Administration of Debio 1450 to Patients Undergoing Hip Replacement Surgery

Bone Diseases, Infectious

United States
Takeda

Withdrawn

A Phase 1, Single and Multiple Dose Study of TAK-137

Healthy Japanese Adult Male

Japan
Takeda

Terminated

Safety, Tolerability, and Pharmacokinetics of Multiple Rising Doses of TAK-137 in Adults With Attention-Deficit/Hyperactivity Disorder.

Attention-Deficit/Hyperactivity Disorder

United States
Debiopharm International SA

Completed

A Dose-Finding Study of the Second Mitochondrial Activator of Caspases (SMAC) Mimetic Debio 1143 When Given in Combination With Avelumab to Participants With Advanced Solid Malignancies and to Participants With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) After Platinum-Based Therapy

Neoplasms | Carcinoma, Non-Small-Cell Lung

Canada, Poland, Romania
Chiesi Farmaceutici S.p.A.

Completed

A Study to Compare the Effects of Two Propellants in Adults With Mild Asthma

Asthma

United Kingdom
Debiopharm International SA

Recruiting

Study of Oral Debio 0123 in Combination With Carboplatin in Participants With Advanced Solid Tumors

Advanced Solid Tumors

Netherlands, Spain
Debiopharm International SA

Terminated

Debio 1143 in Combination With Carboplatin and Paclitaxel in Patient With Advanced Solid Malignancies

Solid Tumors

France
Debiopharm International SA

Recruiting

A Study to Assess the Efficacy, Safety and Pharmacokinetics of Debio 4326 in Pediatric Participants Receiving Gonadotropin-Releasing Hormone Agonist Therapy for Central Precocious Puberty (LIBELULA)

Central Precocious Puberty

United States
Ascentage Pharma Group Inc.

Recruiting

APG-1387 in Patients With Advanced Solid Tumors or Hematologic Malignancies

Advanced Solid Tumors or Hematologic Malignancies

United States
Ascentage Pharma Group Inc.
HealthQuest Pharma Inc.

Completed

APG-1387 Study of Safety, Tolerability ,PK/PD in Patients With Chronic Hepatitis B

Chronic Hepatitis B

China
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating the Relative Bioavailability and Food Effect of a Tablet Formulation of VX-147

Focal Segmental Glomerulosclerosis (FSGS)

United States
Ichnos Sciences SA
Glenmark Pharmaceuticals S.A.

Recruiting

Study of ISB 1342, a CD38/CD3 Bispecific Antibody, in Subjects With Previously Treated Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

United States, France
University Hospital, Tours

Completed

Study of Hemodynamic Conditions Measured During Hepatectomy (DEBIFOIE)

Liver Dysfunction | Circulatory; Change

France
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

Phase III Xevinapant (Debio 1143) and Radiotherapy in Resected LA SCCHN, High Risk, Cisplatin-ineligible Participants (XRAY VISION)

Head and Neck Cancer

United States, China, Belgium, Taiwan, Korea, Republic of, Japan, Israel, Brazil, Greece, Mexico, United Kingdom, Argentina, Austria, Czechia, France, Georgia, Germany, India, Italy, Portugal, Romania, Spain, Switzerland, Netherlands, P... and more
ModernaTX, Inc.

Recruiting

A Study of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus in Pregnant Women and in Infants Born to Vaccinated Mothers

Respiratory Syncytial Virus

Canada, United Kingdom, Japan, United States, Chile, Denmark, Panama, South Africa
ModernaTX, Inc.

Completed

Dose-Finding Trial to Evaluate the Safety and Immunogenicity of Cytomegalovirus (CMV) Vaccine mRNA-1647 in Healthy Adults

Cytomegalovirus Infection

United States
ModernaTX, Inc.

Completed

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of Cytomegalovirus (CMV) Vaccine mRNA-1647

Cytomegalovirus Infection

United States
ModernaTX, Inc.

Active, not recruiting

Moderna Vaccine mRNA-1345 Observational Respiratory Syncytial Virus (RSV) Study

Respiratory Syncytial Virus

United States
ModernaTX, Inc.

Recruiting

A Study to Investigate the Immunogenicity and Safety of mRNA-1345, an mRNA Vaccine Targeting Respiratory Syncytial Virus, in High-risk Adults

Respiratory Syncytial Virus

Canada, United States, United Kingdom, Puerto Rico
Agalimmune Ltd.

Completed

Study to Evaluate Safety & Tolerability of AGI-134 in Solid Tumour

Superficial, Palpable, Unresectable/Metastatic Solid Tumour

United States, Israel, United Kingdom
Rubius Therapeutics

Terminated

Safety and Tolerability of RTX-134 in Adults With Phenylketonuria

Phenylketonurias

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Single Ascending Dose of GAP-134 as a 24-hour IV Infusion in Healthy Japanese Males

Arrhythmia

Japan
Harvard Medical School (HMS and HSDM)
Brigham and Women's Hospital

Active, not recruiting

Cash Benefits and Reproductive/Perinatal Health

Pregnancy Related | Miscarriage | Maternal Care Patterns

United States
Harvard Medical School (HMS and HSDM)
Brigham and Women's Hospital; Cambridge Health Alliance

Active, not recruiting

Effect of Cash Benefits on Health Care Utilization

Health Care Utilization

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of GAP-134 Administered Intravenously

Arrhythmia

United States
Ascentage Pharma Group Inc.

Recruiting

Dose-escalation Study of APG-1387 and Toripalimab in Solid Tumors

Advanced Solid Tumor

China
ModernaTX, Inc.

Enrolling by invitation

A Long-Term Extension Study to Evaluate the Immunogenicity and Safety of Cytomegalovirus (CMV) mRNA-1647 Vaccine

Cytomegalovirus Infection

United States
Bristol-Myers Squibb

Completed

Study of MDX-1342 in Patients With Chronic Lymphocytic Leukemia (CLL) (MDX1342-02)

Chronic Lymphocytic Leukemia

United States
Celldex Therapeutics

Completed

Phase I Study of CDX-1307, hCG-B Vaccine, for Patients With Incurable, Locally Advanced or Metastatic Breast, Colorectal, Pancreatic, Bladder or Ovarian Cancer (CDX1307-02)

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Bladder Cancer

United States
ModernaTX, Inc.

Recruiting

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Allogenic Hematopoietic Cell Transplantation (HCT) Participants.

Cytomegalovirus Infection

United States
ModernaTX, Inc.

Active, not recruiting

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Healthy Participants 16 to 40 Years of Age

Cytomegalovirus Infection

United States, Australia, Canada, France, Belgium, Germany, Israel, Italy, United Kingdom, Spain, Estonia, Finland, Japan
ModernaTX, Inc.

Active, not recruiting

A Study of mRNA-1345, an mRNA Vaccine Targeting Respiratory Syncytial Virus, in Children 2 to <18 Years of Age at High Risk of Respiratory Syncytial Virus

Respiratory Syncytial Virus

United States, Panama
ModernaTX, Inc.

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) in Adults ≥60 Years of Age

Respiratory Syncytial Virus

United States, Spain, Taiwan, Korea, Republic of, Singapore, Canada, Belgium, Finland, Japan, United Kingdom, Chile, New Zealand, South Africa, Australia, Puerto Rico, Argentina, Costa Rica, Poland, Bangladesh, Colombia, Germany, ... and more
Vertex Pharmaceuticals Incorporated

Completed

Phase 2a Study of VX-147 in Adults With APOL1-mediated Focal Segmental Glomerulosclerosis

Glomerulosclerosis, Focal Segmental

United States, France, United Kingdom, Puerto Rico

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