Search clinical trials for: Defactinib Hydrochloride

Total 7379 results

Zagazig University

Completed

Insulin Sensitizers Role in Control of PCOS Vicious Cycle.

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Egypt
National Cancer Institute (NCI)

Completed

Erlotinib in Treating Patients With Persistent or Recurrent Cancer of the Cervix

Cervical Squamous Cell Carcinoma | Recurrent Cervical Cancer

United States
Xijing Hospital

Recruiting

Association Between Postoperative Administration of L-Arginine and CSA-AKI

Acute Kidney Injury

China
Shanghai Mental Health Center
Yantai University

Recruiting

Assessing Dopamine Transporter Occupancy in the Patients With Depression Brain With Toludesvenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)

Major Depressive Disorder

China
Cancer Institute and Hospital, Chinese Academy...

Recruiting

TQB2450 Combined With Anlotinib Hydrochloride in the Perioperative Treatment of Hepatocellular Carcinoma Hydrochloride Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With a High Risk of Recurrence or Metastasis

Patients With Resectable Hepatocellular Carcinoma Who Are at High Risk of Recurrence or Metastasi

China
Eiger BioPharmaceuticals

Completed

Safety and Tolerability Study of Clemizole Hydrochloride to Treat Hepatitis C in Subjects Who Are Treatment-Naive (CLEAN-1)

Hepatitis C
Millendo Therapeutics US, Inc.

Terminated

Nevanimibe HCl for the Treatment of Classic CAH

Congenital Adrenal Hyperplasia

Spain, Israel, France, Brazil, Czechia
Medstar Health Research Institute

Completed

The Effect of Reloading Prasugrel in a Patient Who Has Already Received a Loading Dose (LD) of Clopidogrel (SWITCH 600/60)

Acute Coronary Syndrome

United States
National Cancer Institute (NCI)

Completed

Pazopanib Hydrochloride in Treating Patients With Advanced Thyroid Cancer

Recurrent Thyroid Gland Carcinoma | Thyroid Gland Anaplastic Carcinoma | Stage III Differentiated Thyroid Gland Carcinoma AJCC v7 | Stage IVA Differentiated Thyroid Gland Carcinoma AJCC v7 | Stage IVB Differentiated Thyroid Gland Carcinoma AJCC v7 | Stage IVC Differentiated Thyroid Gland Carcinoma... and other conditions

United States, Taiwan, Australia, Singapore, China
New Approaches to Brain Tumor Therapy Consortium
National Cancer Institute (NCI)

Completed

Procarbazine in Treating Patients With Recurrent Brain Tumor

Brain and Central Nervous System Tumors

United States
Toray Industries, Inc

Completed

Phase II Study of TRK-820 Soft Capsules - Intractable Pruritus in Patients With Chronic Liver Disease -

Pruritus With Chronic Liver Disease

Japan
M.D. Anderson Cancer Center
OSI Pharmaceuticals

Completed

Tarceva With Whole Brain Radiation Therapy - Brain Mets From Non-Small Cell Lung Cancer

Brain Cancer | Non-small Cell Lung Cancer

United States
St. Jude Children's Research Hospital
Duke University; Rady Children's Hospital, San Diego

Completed

Erlotinib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Glioma

Brain and Central Nervous System Tumors

United States
Genzyme, a Sanofi Company

Completed

A Study of the Safety and Efficacy of Patients With Familial Hypercholesterolaemia Taking Colesevelam as add-on Therapy to Their Existing Medication

Familial Hypercholesterolemia

Netherlands, France, Germany, Sweden, United Kingdom
National Cancer Institute (NCI)

Completed

S0341: Erlotinib in Treating Patients With Advanced Primary Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Adenocarcinoma of the Lung | Large Cell Lung Cancer

United States
Shanghai Jiao Tong University School of Medicine

Completed

Itopride as an Adjuvant for Bowel Preparation in Patients With Chronic Constipation is Effective

Constipation

China
National Cancer Institute (NCI)

Completed

S0727 Gemcitabine Hydrochloride and Erlotinib Hydrochloride With or Without Monoclonal Antibody Therapy in Treating Patients With Metastatic Pancreatic Cancer That Cannot Be Removed By Surgery

Stage IV Pancreatic Cancer

United States
Jinming Yu

Recruiting

A Phase Ib Study of TQB2450 Combined With Anlotinib in Patients With Limited Stage Small Cell Lung Cancer After First-line Radiotherapy and Chemotherapy

Limited Stage Small Cell Lung Cancer | Not Progressed After First-line Chemoradiotherapy

China
Claudia R. Morris
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Sickle Cell Disease Treatment With Arginine Therapy (STArT) Trial (STArT)

Sickle Cell Disease

United States
Shanghai Mental Health Center
Yantai University

Completed

Assessing Dopamine Transporter Occupancy in the Healthy Adult Brain With Toludivenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)

Major Depressive Disorder

China
Gyeongsang National University Hospital

Completed

Fixed-dose vs. Phenotype-based PrAsugrel Dose to MATCH Therapeutic Zone in Asians With Acute Coronary Syndrome

Bleeding | Acute Coronary Syndrome | Platelet Thrombus

Korea, Republic of
Advenchen Laboratories, LLC

Terminated

Phase 1/2a Evaluation of AL3818 in Subjects With Recurrent or Metastatic Endometrial, Ovarian or Cervical Cancer (AL3818-US-001) (AL3818)

Cervical Cancer | Ovarian Cancer | Endometrial Cancer

United States
Amicus Therapeutics

Terminated

Open-Label Phase 3 Long-Term Safety Study of Migalastat (AT1001-041)

Fabry Disease

Australia, United States, Italy, Spain, Belgium, Turkey, Brazil, Argentina, United Kingdom, Denmark, France, Canada, Egypt
University of Florida

Completed

Prasugrel Re-load Strategies

Coronary Artery Disease

United States
University of Milan

Completed

The Effect of Prasugrel on Bronchial Hyperreactivity and on Markers of Inflammation in Patients With Chronic Asthma (PRINA)

Chronic Asthma

Italy
Rajmonda Nallbani-Komoni

Unknown

Intravenous Lidocaine for Perioperative and Postoperative Analgesia

Analgesic Drug Dependence

Kosovo
Celgene

Completed

AMR PH GL 2007 CL001 Phase 3 Trial in Patients With Small Cell Lung Cancer After Failure of First-Line Chemotherapy

Small Cell Lung Cancer

United States, United Kingdom, Australia, France, Canada, Netherlands, Poland, Spain, Switzerland, Italy, Denmark, Hungary, Germany, Bulgaria, Czechia, Austria, Belgium
Roswell Park Cancer Institute

Terminated

Erlotinib in Treating Patients With Stage III or Stage IV Pancreatic Cancer

Pancreatic Cancer

United States
National Cancer Institute (NCI)

Completed

Erlotinib in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
National Cancer Institute (NCI)

Completed

Erlotinib Hydrochloride in Treating Patients With Advanced Esophageal Cancer or Stomach Cancer

Adenocarcinoma of the Gastroesophageal Junction | Squamous Cell Carcinoma of the Esophagus | Adenocarcinoma of the Esophagus | Recurrent Esophageal Cancer | Stage IV Esophageal Cancer | Stage III Esophageal Cancer

United States
National Cancer Institute (NCI)

Completed

Erlotinib in Treating Patients With Locally Advanced or Metastatic Papillary Renal Cell Cancer

Stage III Renal Cell Cancer | Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer

United States
National Cancer Institute (NCI)

Completed

Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction

Recurrent Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Bladder Cancer | Stage IV Bladder Cancer | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IV Ovarian Epithelial Cancer | Stage... and other conditions

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Oxaliplatin, Gemcitabine, Erlotinib, and Radiation Therapy in Treating Patients With Unresectable and/or Metastatic Pancreatic Cancer or Biliary Tract Cancer

Pancreatic Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Amicus Therapeutics

Terminated

Study to Evaluate the Safety of AT2220 (Duvoglustat) in Pompe Disease

Pompe Disease

United States
University of Colorado, Denver
Daiichi Sankyo, Inc.

Completed

Efficacy of Colesevelam in Subjects With Type 1 Diabetes Mellitus

Diabetes Mellitus, Type 1 | Hyperlipidemias

United States
Gil Yosipovitch

Terminated

Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine

Pruritus

United States
Jonsson Comprehensive Cancer Center
Genentech, Inc.

Completed

Trastuzumab and Erlotinib as First-Line Therapy in Treating Women With Metastatic Breast Cancer Associated With HER2/Neu Overexpression

Breast Cancer

United States
Eisai Co., Ltd.

Completed

Effects of Lysozyme on Acute Exacerbation of Chronic Obstructive Pulmonary Disease : A Randomised Placebo-Controlled Study

COPD

Japan
National Center for Complementary and Integrative...

Completed

Effects of Oral Glucosamine on Insulin and Blood Vessel Activity in Normal and Obese People

Obesity | Insulin Resistance

United States
University of Manchester
Medical Research Council; JP Moulton Charitable Foundation

Completed

Neurophysiology of Cough Reflex Hypersensitivity (NOTCH)

Cough | Healthy Controls

United Kingdom
M.D. Anderson Cancer Center
Genentech, Inc.; Vanderbilt-Ingram Cancer Center

Completed

Avastin and Tarceva for Locally Advanced or Metastatic Non-Squamous Non-Small-Cell Lung Cancer

Lung Cancer

United States
Astellas Pharma Europe B.V.

Completed

Study of Solifenacin Succinate and Tamsulosin Hydrochloride OCAS in Males With Lower Urinary Tract Symptoms (Neptune)

Lower Urinary Tract Symptoms | Benign Prostatic Hyperplasia

Belgium, Italy, France, Austria, United Kingdom, Netherlands, Hungary, Russian Federation, Poland, Slovakia, Czech Republic, Belarus, Germany
Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Completed

Transversus Abdominis Plane Block and Quadratus Lumborum Block in Pediatric Patients

Pain, Postoperative

Turkey
United Laboratories

Unknown

SINGLE-APPLICATION TERBINAFINE HYDROCHLORIDE (1%) TOPICAL LIQUID SOLUTION VERSUS A SINGLE-APPLICATION BUTENAFINE HYDROCHLORIDE (1%) TOPICAL LIQUID SOLUTION FOR THE TREATMENT OF TINEA PEDIS

Tinea Pedis

Philippines
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Envida...

Terminated

Neurotoxic Adverse Effects of Morphine and Oxycodone for Pain in Terminal Patients With Diminished Renal Function (MOSART)

Pain | Renal Impairment | Terminal Illness

Netherlands
National Cancer Institute (NCI)

Completed

Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive Meningioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor | Adult Grade I Meningioma | Adult Grade II Meningioma | Adult Grade III Meningioma

United States
University of Medicine and Dentistry of New Jersey
National Cancer Institute (NCI); Genentech, Inc.; Schering-Plough

Withdrawn

QOL-Stereotactic RadioSurgery, Temozolomide + Erlotinib-Rx of 1-3 Brain Metastases in NSCLC

Lung Cancer | Metastatic Cancer
Cephalon

Completed

Study of Bendamustine Combined With Bortezomib for Patients With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
Pfizer

Completed

A Clinical Study To Characterize The Pharmacokinetics And The Effects Of Food On Oxycodone In Healthy Volunteers

Chronic Pain | Analgesia | Acute Pain | Opioid-related Disorders | Narcotic Abuse

United States
Daewoong Pharmaceutical Co. LTD.

Recruiting

A Study to Evaluate the Improvement Effect on Subjective Symptom of FEXUCLUE Tab

Gastroesophageal Reflux Disease

Korea, Republic of

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