Search clinical trials for: Dexmedetomidine Ketamine

Total 2861 results

Mid-Atlantic Epilepsy and Sleep Center, LLC

Withdrawn

Levetiracetam, Lacosamide and Ketamine as Adjunctive Treatment of Refractory Status Epilepticus

Epilepsy | Status Epilepticus

United States
University of Dundee
Tenovus Scotland

Completed

Antibiotics for the Treatment of Ulcerative Colitis

Colitis, Ulcerative

United Kingdom
Santa Barbara Cottage Hospital

Withdrawn

Alcohol Withdrawal Syndrome Treated With Adjunctive Phenobarbital or Ketamine (PKAT)

Alcohol Withdrawal Syndrome
University of Vermont
American Society of Colon and Rectal Surgeons

Completed

Pre-Emptive Analgesia in Ano-Rectal Surgery (PEAARS)

Rectal Fistula | Hemorrhoids | Fissure in Ano | Anal Condyloma

United States
TC Erciyes University

Completed

Comparison of Preincisional Infiltrated Dexmedetomidine and Lidocaine Plus Adrenaline for Nasal Sephoplasty Surgery.

Pain | Surgery
National Research Council, Spain

Completed

Olive Oil and Nampt on Postprandial Inflammation and Atherosclerosis in the Setting of Metabolic Syndrome (OLNAMS)

Metabolic Syndrome

Spain
Ain Shams University

Active, not recruiting

Dexmedetomidine Versus Magnesium Infusion in Reducing Agitations in Pediatric Patients Undergoing Adenotonsillectomy

Postoperative Agitations in Pediatric Patients

Egypt
Chosun University Hospital

Completed

Effect of Dexmedetomidine on Recovery Profiles of Elderly Patients (CSUHAPM)

Anesthesia | Elderly Patients | Emergence From Anesthesia | Effects of Dexmedetomidine | Recovery From Anesthesia

Korea, Republic of
VA Office of Research and Development

Withdrawn

VA Aripiprazole vs Esketamine for Treatment Resistant Depression (VAST-D II)

Depressive Disorder, Major

United States
Janssen Research & Development, LLC

Completed

Pharmacokinetic, Safety, and Tolerability Study of Intranasally Administered Esketamine in Healthy Han Chinese, Korean, Japanese, and Caucasian Participants and the Effects of Rifampin on the Pharmacokinetics of Intranasally Administered Esketamine

Healthy

United States
Alcon, a Novartis Company

Completed

Comparison of Intraocular Pressure (IOP)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic Solution

Ocular Hypertension | Open-Angle Glaucoma

Japan
University of Nebraska
National Cancer Institute (NCI); Adherex Technologies, Inc.

Completed

ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer

Pancreatic Adenocarcinoma | Metastatic Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Stage IVA Pancreatic Cancer | Stage IVB Pancreatic Cancer | Stage IIIA Gallbladder Cancer | Stage IIIB Gallbladder Cancer | Stage IVA Gallbladder Cancer | Stage IVB Gallbladder Cancer | Gallbladder Adenocarcinoma and other conditions

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Effect of Sarilumab on Patient-reported Outcomes in Patients With Active Rheumatoid Arthritis (SariPRO)

Rheumatoid Arthritis

France
Chosun University Hospital

Completed

Effect of Dexmedetomidine After Thyroidectomy

Thyroid Tumor

Korea, Republic of
Menoufia University

Completed

Conscious Sedation for Epilepsy Surgery

Epilepsy
Lawson Health Research Institute

Unknown

Evaluation of Motor Sparing Knee Block to Infiltration Analgesia for Pain Following Knee Arthroplasty

Osteoarthritis | Pain Management | Knee Arthroplasty

Canada
Zagazig University

Completed

Comparing Efficacy Preoperative Nebulized: Ketamine , Mgspo4 ,and Lidocaine In Attenuating Endotracheal Sore Throat

Sore Throat

Egypt
Mack Mitchell
National Institute on Alcohol Abuse and Alcoholism (NIAAA); The Cleveland Clinic and other collaborators

Completed

Efficacy Study of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic Hepatitis

Acute Alcoholic Hepatitis

United States
Rabin Medical Center

Suspended

Ketamine vs Propofol for Sedation During Pediatric Bronchoscopy

Paediatric Flexible Bronchoscopy
Janssen Research & Development, LLC

Completed

Study to Assess the Effects of Allergic Rhinitis and Co-administration of Mometasone or Oxymetazoline on the Pharmacokinetics, Safety, and Tolerability of Intranasal Esketamine

Allergic Rhinitis

Germany
University of Maryland, Baltimore

Completed

Pharmacokinetics of Antiepileptics in Patients on CRRT (PADRE)

Renal Insufficiency | Renal Failure | Acute Kidney Injury | Pharmacokinetics

United States
University of California, San Francisco

Completed

Effect of Changing Physiological Conditions on Myogenic Oscillations: Pilot Study

Vascular Diseases

United States
Medical College of Wisconsin

Completed

Dexmedetomidine and Propofol for Pediatric MRI Sedation

Headache | Neurofibromatoses | Abdominal Neoplasm | Tumor | Seizure Disorder | Hydrocephalus | Spine Deformity

United States
Express Specialty Pharmacy

Completed

Prospective Analgesic Compound Efficacy (PACE) Study (PACE)

Arthritis | Migraine | Headache | Radiculopathy | Gout | Synovitis | Tendonitis | Muscle Spasms
Janssen Research & Development, LLC

Completed

Pharmacokinetic Study of Intranasal Esketamine and Its Effects on the Pharmacokinetics of Orally-Administered Midazolam and Bupropion in Healthy Participants

Healthy

Belgium
Wake Forest University Health Sciences

Withdrawn

Opioid-Free Pain Control Regiment Following Robotic Radical Prostatectomy

Radical Prostatectomies

United States
Medical College of Wisconsin

Completed

Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients

Wounds and Injuries | Rib Fractures

United States
Ain Shams University

Completed

Comparison Between Adjuvants Added to Bupivacaine in Adductor Canal Block

Anesthesia

Egypt
Hasanuddin University

Completed

Lidocaine, Povidone Iodine, and Honey Application on Second-degree Perineal Tear Healing

Perineal Tear

Indonesia
Jawaharlal Institute of Postgraduate Medical Education...

Terminated

Comparison of Disease Modifying Antirheumatic Drugs Therapy in Patients With RA Failing Methotrexate Monotherapy

Rheumatoid Arthritis

India
University of Rochester
Mae Stone Goode Foundation

Completed

Novel Topical Therapies for the Treatment of Genital Pain (Topicals)

Female Genital Diseases

United States
Brooke Army Medical Center

Completed

"THINK Trial: Treatment of Headache With IntraNasal Ketamine: A Randomized Controlled Trial Evaluating the Efficacy of Intranasal Ketamine Versus Standard Therapy in the Management of Primary Headache Syndromes in the Emergency Department" (THINK)

Headache | Intranasal Ketamine

United States
Janssen Research & Development, LLC

Completed

A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-resistant Depression (SUSTAIN-1)

Depressive Disorder, Treatment-Resistant

United States, France, Poland, Belgium, Germany, Spain, Mexico, Turkey, Canada, Brazil, Estonia, Hungary, Slovakia, Sweden, Czechia
Augusta University

Active, not recruiting

[COVID-19] Reduction of Sars-CoV-2 Oral Viral Load With Prophylactic Mouth Rinse

Covid19

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant Depression (TRANSFORM-3)

Depressive Disorder, Treatment-Resistant

United States, France, Belgium, Spain, Poland, Bulgaria, South Africa, Finland, Brazil, Sweden, United Kingdom, Lithuania
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression (TRANSFORM-2)

Treatment-resistant Depression

United States, Poland, Germany, Spain, Czechia
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression (TRANSFORM-1)

Treatment-resistant Depression

United States, France, Belgium, Mexico, Canada, Brazil, Estonia, Hungary, Slovakia
Jeffrey Moak

Not yet recruiting

Prevention of Post-Operative Cardiac Arrhythmias (POCA)

Cardiac; Dysrhythmia, Postoperative | Congenital Heart Surgery
Jeremy Kearns

Terminated

Continuous Nerve Block Block vs Combination of Single Block Plus Intravenous Lidocaine for Postoperative Pain.

Postoperative Pain

United States
Tang-Du Hospital

Unknown

Effects of Dexmedetomidine on Postoperative Cognitive Dysfunction During One-lung Ventilation in Elder Patients

Postoperative Confusion
Maximilian Diehn
AstraZeneca

Recruiting

Personalized Escalation of Consolidation Treatment Following Chemoradiotherapy and Immunotherapy in Stage III NSCLC in Stage III NSCLC

Non Small Cell Lung Cancer | NSCLC, Stage III | Nsclc

United States
Second Affiliated Hospital, School of Medicine,...
Fudan University; Peking Union Medical College Hospital; West China Hospital; The... and other collaborators

Recruiting

Platform Adaptive Embedded Trial for Acute Respiratory Distress Syndrome (PETARDS)

Acute Respiratory Distress Syndrome

China
The Camelot Foundation

Completed

The Fleming [FMTVDM] Directed CoVid-19 Treatment Protocol (FMTVDM)

CoVid 19 Positive

United States
Theodor Bilharz Research Institute

Completed

Dexmedetomidine and Desflurane Consumption

Anesthesia

Egypt
Mayo Clinic

Not yet recruiting

Nasal Iodine Swab Versus Oral Antibiotic to Prevent Surgical Site Infection After Undergoing Mohs Micrographic Surgery

Skin Cancer | Skin Cancer Face | Malignant Cutaneous Adnexal Neoplasm

United States
Manal El Namrawy

Unknown

Posterior Segment Intrusion Using Miniplates

Orthodontic Anchorage Procedures
King Abdulaziz University

Completed

The Efficacy of Pre-procedural Mouth Rinses on COVID-19 Saliva Viral Load

COVID-19 | Covid19 | SARS-CoV-2 | Coronavirus | Saliva | Viral Load | Polymerase Chain Reaction | Mouthwashes

Saudi Arabia
St. Jude Children's Research Hospital

Recruiting

Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Myeloid Sarcoma | Chronic Myeloid Leukemia (CML) | Non-Hodgkin Lymphoma (NHL) | Juvenile Myelomonocytic Leukemia (JMML)

United States
St. Jude Children's Research Hospital
AbbVie

Not yet recruiting

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

T-cell Lymphoma | T-cell Acute Lymphoblastic Leukemia | Mixed Phenotype Acute Leukemia

United States
University of Illinois College of Medicine at Peoria

Unknown

Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

Pain, Postoperative | Constipation | Colon Cancer | Colonic Neoplasms | Ileus | Rectum Cancer | Constipation Drug Induced | Rectum Neoplasm | Colonic Diverticulitis | Ileus Paralytic | Colon Diverticulosis | Ileus; Mechanical

United States

Search clinical trials for: Dexmedetomidine Ketamine

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