Search clinical trials for: Dimebon Dextromethorphan

Total 193 results

Pfizer
Medivation, Inc.

Completed

A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)

Huntington Disease | Alzheimer's Disease

United States
Pfizer
Medivation, Inc.

Completed

A Phase 1 Study To Evaluate The Effect Of Dimebon On The Pharmacokinetics Of Dextromethorphan

Alzheimer Disease | Huntington Disease

United States
Medivation, Inc.
Pfizer

Terminated

An Extension of the CONCERT Protocol (DIM18) (CONCERT PLUS)

Alzheimer's Disease
Pfizer
Medivation, Inc.

Completed

A Phase 1 Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF-01913539] In Japanese And Western Healthy Subjects

Alzheimer's Disease | Huntington's Disease

United States
Pfizer
Medivation, Inc.

Completed

A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function

Alzheimer's Disease | Huntington's Disease

United States
Pfizer
Medivation, Inc.

Completed

Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [Pf-01913539] In Subjects With Hepatic Impairment And Normal Hepatic Function

Hepatic Failure

United States
Pfizer
Medivation, Inc.

Completed

A Phase 1 Trial To Assess The Safety And Pharmacokinetics Of Single, Ascending, Oral Doses Of Dimebon In Healthy Adults

Healthy Volunteers

Belgium
Medivation, Inc.
Huntington Study Group

Completed

Safety Study of the Novel Drug Dimebon to Treat Patients With Huntington's Disease

Huntington's Disease

United States
Medivation, Inc.

Completed

A Safety and Efficacy Study of Oral Dimebon in Patients With Mild-To-Moderate Alzheimer's Disease (CONNECTION)

Alzheimer's Disease

United States
Pfizer
Medivation, Inc.

Completed

A Phase 3 Study To Evaluate The Safety And Tolerability Of Dimebon Patients With Mild To Moderate Alzheimer's Disease

Alzheimer's Disease

Canada, United States, Puerto Rico
Medivation, Inc.
Pfizer

Completed

A Safety and Efficacy Study of Dimebon in Patients With Huntington Disease (HORIZON)

Huntington Disease

Germany, Canada, United States, Denmark, United Kingdom, Australia, Sweden
Medivation, Inc.
Pfizer

Terminated

An Extension of the HORIZON Protocol Evaluating the Safety of Dimebon (Latrepirdine) in Subjects With Huntington Disease (HORIZON PLUS)

Huntington Disease
Pfizer
Medivation, Inc.

Completed

A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Skin

Alzheimer's Disease | Huntington's Disease

United States
Medivation, Inc.

Completed

Double-blind, Placebo-controlled Study of Oral Dimebon in Subjects With Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

Russian Federation
Medivation, Inc.
Huntington Study Group

Completed

A Study of the Novel Drug Dimebon in Patients With Huntington's Disease (DIMOND)

Huntington's Disease

United States
Pfizer
Medivation, Inc.

Terminated

An Extension To The B1451027 Protocol To Evaluate The Long Term Safety And Tolerability Of Dimebon In Patients With Alzheimer's Disease

Alzheimer's Disease

Canada, United States, Puerto Rico
Medivation, Inc.
Pfizer

Terminated

A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease (CONTACT)

Moderate to Severe Alzheimer

Chile, United Kingdom
Bigespas LTD

Recruiting

DMB-I in the Treatment of Alzheimer Type Dementia

Alzheimer Disease | Dementia of Alzheimer Type

Russian Federation
Pfizer
Medivation, Inc.

Terminated

An Extension To The B1451006 Protocol To Evaluate The Safety and Efficacy of Dimebon In Subjects With Moderate-to-Severe Alzheimer's Disease

Alzheimer's Disease

United States
Medivation, Inc.

Terminated

Study of Combination Therapy With Dimebon and Donepezil (Aricept) in Patients With Alzheimer's Disease

Alzheimer's Disease

United States
Montefiore Medical Center

Completed

Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo

Cough Reflex Sensitivity

United States
Pfizer
Medivation, Inc.

Completed

A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects

Alzheimer's Disease | Huntington's Disease

United States
Medivation, Inc.
Pfizer

Completed

Safety and Efficacy Study Evaluating Dimebon in Patients With Mild to Moderate Alzheimer's Disease on Donepezil (CONCERT)

Alzheimer's Disease

France, United Kingdom, Germany, United States, Australia, Belgium, New Zealand, Italy, Sweden, Finland
Medivation, Inc.

Completed

Safety and Tolerability of Dimebon in Patients on Memantine, and Memantine Plus Donepezil

Alzheimer's Disease

United States
Boehringer Ingelheim

Completed

Relative Bioavailability of Dextromethorphan Syrup in Comparison to Dextromethorphan Soft Pastilles in Healthy Male and Female Subjects

Healthy
AmpliMed Corporation

Completed

Safety and Efficacy Study of Imexon for Treatment of Multiple Myeloma Patients

Multiple Myeloma

United States
AmpliMed Corporation

Completed

Safety Study of Imexon Treatment of Patients With Metastatic or Disseminated Malignancy

Neoplasm Metastasis

United States
Boehringer Ingelheim

Completed

Study to Investigate Safety With Special Emphasis on ECG Effects and Tolerability After Oral Doses of Dextromethorphan Hydrobromide Monohydrate in Healthy Male and Female Subjects

Healthy
Pfizer
Medivation, Inc.

Completed

A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers

Alzheimer's Disease | Huntington's Disease

United States
Pfizer

Completed

A Pharmacokinetic (PK) Study Of PF-00299804 And Dextromethorphan In Healthy Volunteers

Healthy Volunteers

Belgium
Pfizer
Medivation, Inc.

Terminated

A Phase 3 Efficacy Study Of Dimebon In Patients With Moderate To Severe Alzheimer's Disease

Alzheimer Disease

United States, Hungary, Germany, Spain, Turkey, Slovakia, Canada, Portugal
University of Rochester
University of Arizona

Completed

Imexon for Relapsed Follicular and Aggressive Lymphomas (ULYM11011)

Follicular Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Lymphoplasmacytic Lymphoma | Diffuse Large B Cell Lymphoma | Small Lymphocytic Lymphoma | Burkitt's Lymphoma

United States
Vimecon GmbH

Terminated

Vimecon CAI Trial for the Interventional Treatment of Paroxysmal Atrial Fibrillation (AF) (CAI)

Atrial Fibrillation

Czechia, Belgium, Germany
National Institute of Neurological Disorders and...

Completed

Dextromethorphan for the Treatment of Parkinson's Disease and Similar Conditions of the Nervous System

Parkinson's Disease | Neurodegenerative Disease

United States
National Institute of Dental and Craniofacial Research...

Completed

Dextromethorphan Versus Placebo for Neuropathic Pain

Diabetic Neuropathies | Neuralgia | Herpes Zoster

United States
University of Florence

Unknown

Grazoprevir and Elbasvir Without Ribavirin for 12 Weeks in Patients With HCV-related Cryoglobulinemic Nephropathy (CRYOKID)

Hepatitis C | Cryoglobulinaemic Glomerulonephritis
Hugo W. Moser Research Institute at Kennedy Krieger...
The Johns Hopkins Institute for Clinical and Translational Research (ICTR)

Completed

Placebo Controlled Trial of Dextromethorphan in Rett Syndrome (PCTDMRTT)

Rett Syndrome

United States
National Institute on Drug Abuse (NIDA)

Unknown

Hyperalgesia in Methadone Patients: Can it be Treated?

Opioid-induced Hyperalgesia

United States
University of Medicine and Dentistry of New Jersey
National Cancer Institute (NCI)

Terminated

Dextromethorphan in Treating Patients With Fatigue Caused by Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Fatigue | Unspecified Adult Solid Tumor, Protocol Specific

United States
Medical University of South Carolina

Completed

A Trial of Dextromethorphan for Treatment of Major Depressive Disorder

Major Depressive Disorder
Nathanael Heckmann

Recruiting

Dextromethorphan for Treatment of Postoperative Pain

Post-operative Pain

United States
Deutsches Herzzentrum Muenchen

Completed

Iodixanol vs. Iomeprol to Prevent Contrast-Induced Nephropathy After Coronary Intervention (CONTRAST)

Renal Insufficiency, Chronic | Coronary Arteriosclerosis | Angioplasty, Transluminal, Percutaneous Coronary

Germany
Pfizer
Medivation, Inc.

Completed

Dimebon (PF-01913539)-Digoxin Drug-Drug Interaction Study In Healthy Subjects

Alzheimer Disease | Huntington Disease

United States
University Hospital, Geneva
Jules Desmeules; Youssef Daali; Kenza Abouir; Eduardo Schiffer; Bernard Walder

Recruiting

Impact of CYP2D6 Genetic Polymorphisms on the Vulnerability to Drug-drug Interactions With Tramadol (PREDICT)

Pain | Interaction

Switzerland
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Dextromethorphan for Diabetic Macular Edema (MiDME2)

Diabetic Macular Edema

United States
Taichung Veterans General Hospital
TSH Biopharm Corporation Limited

Completed

Efficacy Study of Dextromethorphan to Treat Rheumatoid Arthritis

Rheumatoid Arthritis
Profil Institut für Stoffwechselforschung GmbH
Heinrich-Heine University, Duesseldorf

Completed

Dextromethorphan, Amantadine and Glucose Homeostasis in Diabetes Subjects (DXM/AMT)

Type 2 Diabetes Mellitus

Germany
National Cheng-Kung University Hospital
National Health Research Institutes, Taiwan; TTY Biopharm

Completed

Add-on Dextromethorphan in Bipolar Disorders (DM)

Bipolar Disorder

Taiwan
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

Effects of Isotretinoin on CYP2D6 Activity

CYP2D6 Polymorphism

United States
Merck Sharp & Dohme LLC

Completed

Study of the Effect of Single Doses of MK2637 and Dextromethorphan on Cerebral Cortex Excitability (2637-008)

Schizophrenia

3

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