Search clinical trials for: Dimebon MR1

Total 4857 results

Pfizer
Medivation, Inc.

Completed

A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)

Huntington Disease | Alzheimer's Disease

United States
Medivation, Inc.
Pfizer

Terminated

An Extension of the CONCERT Protocol (DIM18) (CONCERT PLUS)

Alzheimer's Disease
Pfizer
Medivation, Inc.

Completed

A Phase 1 Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF-01913539] In Japanese And Western Healthy Subjects

Alzheimer's Disease | Huntington's Disease

United States
Pfizer
Medivation, Inc.

Completed

A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function

Alzheimer's Disease | Huntington's Disease

United States
Pfizer
Medivation, Inc.

Completed

Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [Pf-01913539] In Subjects With Hepatic Impairment And Normal Hepatic Function

Hepatic Failure

United States
Pfizer
Medivation, Inc.

Completed

A Phase 1 Trial To Assess The Safety And Pharmacokinetics Of Single, Ascending, Oral Doses Of Dimebon In Healthy Adults

Healthy Volunteers

Belgium
Medivation, Inc.
Huntington Study Group

Completed

Safety Study of the Novel Drug Dimebon to Treat Patients With Huntington's Disease

Huntington's Disease

United States
Medivation, Inc.

Completed

A Safety and Efficacy Study of Oral Dimebon in Patients With Mild-To-Moderate Alzheimer's Disease (CONNECTION)

Alzheimer's Disease

United States
Pfizer
Medivation, Inc.

Completed

A Phase 3 Study To Evaluate The Safety And Tolerability Of Dimebon Patients With Mild To Moderate Alzheimer's Disease

Alzheimer's Disease

Canada, United States, Puerto Rico
Medivation, Inc.
Pfizer

Completed

A Safety and Efficacy Study of Dimebon in Patients With Huntington Disease (HORIZON)

Huntington Disease

Germany, Canada, United States, Denmark, United Kingdom, Australia, Sweden
Medivation, Inc.
Pfizer

Terminated

An Extension of the HORIZON Protocol Evaluating the Safety of Dimebon (Latrepirdine) in Subjects With Huntington Disease (HORIZON PLUS)

Huntington Disease
Pfizer
Medivation, Inc.

Completed

A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Skin

Alzheimer's Disease | Huntington's Disease

United States
Medivation, Inc.

Completed

Double-blind, Placebo-controlled Study of Oral Dimebon in Subjects With Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

Russian Federation
Medivation, Inc.
Huntington Study Group

Completed

A Study of the Novel Drug Dimebon in Patients With Huntington's Disease (DIMOND)

Huntington's Disease

United States
Pfizer
Medivation, Inc.

Terminated

An Extension To The B1451027 Protocol To Evaluate The Long Term Safety And Tolerability Of Dimebon In Patients With Alzheimer's Disease

Alzheimer's Disease

Canada, United States, Puerto Rico
Medivation, Inc.
Pfizer

Terminated

A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease (CONTACT)

Moderate to Severe Alzheimer

Chile, United Kingdom
Bigespas LTD

Recruiting

DMB-I in the Treatment of Alzheimer Type Dementia

Alzheimer Disease | Dementia of Alzheimer Type

Russian Federation
Pfizer
Medivation, Inc.

Terminated

An Extension To The B1451006 Protocol To Evaluate The Safety and Efficacy of Dimebon In Subjects With Moderate-to-Severe Alzheimer's Disease

Alzheimer's Disease

United States
GlaxoSmithKline

Completed

An Open Label, Randomised, Repeat Dose Study to Assess the Pharmacokinetic Performance of Five Ezogabine/Retigabine Modified Release (MR) Formulations at Steady State Compared to the Immediate Release (IR) Formulation.

Epilepsy

United States
M.D. Anderson Cancer Center

Completed

Measuring Non-Enhancing Glioblastoma Progression

Glioblastoma | Brain Tumor

United States
Medivation, Inc.

Terminated

Study of Combination Therapy With Dimebon and Donepezil (Aricept) in Patients With Alzheimer's Disease

Alzheimer's Disease

United States
Eline C. B. Eskes

Recruiting

Magnetic Resonance Spectroscopy in Acid Sphingomyelinase Deficiency (MONACO)

Asmd, Visceral Type

Netherlands
Pfizer
Medivation, Inc.

Completed

A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects

Alzheimer's Disease | Huntington's Disease

United States
Medivation, Inc.
Pfizer

Completed

Safety and Efficacy Study Evaluating Dimebon in Patients With Mild to Moderate Alzheimer's Disease on Donepezil (CONCERT)

Alzheimer's Disease

France, United Kingdom, Germany, United States, Australia, Belgium, New Zealand, Italy, Sweden, Finland
Mayo Clinic
National Center for Complementary and Integrative Health (NCCIH)

Enrolling by invitation

Magnetic Resonance Elastography of Myofascial Pain Syndrome

Myofascial Pain

United States
Medivation, Inc.

Completed

Safety and Tolerability of Dimebon in Patients on Memantine, and Memantine Plus Donepezil

Alzheimer's Disease

United States
University of Michigan

Withdrawn

Magnetic Resonance (MR) Spectroscopy and Diffusion Tensor Imaging in Determining Brain Injury and Subsequent Clinical Outcome in Patients of Moderate Brain Trauma

Brain Trauma

United States
AmpliMed Corporation

Completed

Safety and Efficacy Study of Imexon for Treatment of Multiple Myeloma Patients

Multiple Myeloma

United States
AmpliMed Corporation

Completed

Safety Study of Imexon Treatment of Patients With Metastatic or Disseminated Malignancy

Neoplasm Metastasis

United States
Pfizer
Medivation, Inc.

Completed

A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers

Alzheimer's Disease | Huntington's Disease

United States
Shaare Zedek Medical Center
The Hospital for Sick Children; Rambam Health Care Campus; Children's Hospital... and other collaborators

Completed

The ImageKids Study: Developing the pMEDIC and the PICMI

Crohn's Disease

Israel
Pfizer
Medivation, Inc.

Terminated

A Phase 3 Efficacy Study Of Dimebon In Patients With Moderate To Severe Alzheimer's Disease

Alzheimer Disease

United States, Hungary, Germany, Spain, Turkey, Slovakia, Canada, Portugal
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Non-Invasive Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy Techniques (MRS) for Assessing Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer

Breast Cancer

United States
University of Rochester
University of Arizona

Completed

Imexon for Relapsed Follicular and Aggressive Lymphomas (ULYM11011)

Follicular Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Lymphoplasmacytic Lymphoma | Diffuse Large B Cell Lymphoma | Small Lymphocytic Lymphoma | Burkitt's Lymphoma

United States
Memorial Sloan Kettering Cancer Center
National Institutes of Health (NIH)

Active, not recruiting

Dynamic Contrast Enhanced MRI (DCE-MRI) Diffusion Weighted MRI (DW-MRI) and Magnetic Resonance Spectroscopy (MRS) of Head and Neck Tumors

Head and Neck Cancer

United States
University of Texas Southwestern Medical Center
Cancer Prevention Research Institute of Texas

Completed

Clinical Development of MR Spectroscopy and Imaging in Brain Cancers

Malignant Gliomas | Astrocytomas | Oligodendrogliomas

United States
AB-CT - Advanced Breast-CT GmbH
CRO Dr. med. Kottmann GmbH; RQM+ (Germany) GmbH

Recruiting

Comparison of Low-dose Spiral Breast CT With MRI in Major Indications of MRI for Breast Diagnostics

Breast Cancer Diagnosis

Netherlands, Germany
Vimecon GmbH

Terminated

Vimecon CAI Trial for the Interventional Treatment of Paroxysmal Atrial Fibrillation (AF) (CAI)

Atrial Fibrillation

Czechia, Belgium, Germany
OHSU Knight Cancer Institute
Radiological Society of North America; Medical Research Foundation, Oregon

Terminated

Magnetic Resonance Imaging (MRI) in the Assessment of Head and Neck Squamous Cell Carcinoma (HNSCC) Response

Head and Neck Cancer

United States
Shire

Completed

Sophisticated Assessment of Disease Burden in Patients With Fabry Disease (SOPHIA)

Fabry Disease

Finland, Sweden, Germany, Belgium, Czechia, Denmark
Massachusetts General Hospital
President and Fellows of Harvard College; Nutrition Obesity Research Center...

Completed

Mechanisms of Diastolic Dysfunction Among Persons With HIV Compared With Non-HIV Control Subjects

Myocardial Fibrosis | HIV | Diastolic Dysfunction

United States
University of Nottingham

Unknown

Perfusion MRI in Reversible Cerebral Vasoconstriction Syndrome

Reversible Cerebral Vasoconstriction Syndrome

United Kingdom
University of Exeter

Active, not recruiting

Can Ultrasound be Used as a Measure of Muscle Quality? A Validation Study Comparing Ultrasound With MRI and MRS in Older and Younger Persons.

Muscle Atrophy

United Kingdom
Jonsson Comprehensive Cancer Center
U.S. Army Medical Research and Development Command; U.S. Army Medical Research...

Completed

MR Correlated Spectroscopic Imaging for Diagnosing Breast Cancer

Breast Carcinoma | Malignant Breast Neoplasm | Benign Breast Neoplasm

United States
The HIV Netherlands Australia Thailand Research...
Chulalongkorn University; University of Hawaii; South East Asia Research Collaboration... and other collaborators

Completed

Neurocognitive Impairment and Psychiatric Comorbidities in HIV-1

HIV Infections

Thailand
University Hospital, Strasbourg, France

Recruiting

Intracranial Arterial Stenosis and Resin of Cannabis Use

Cannabis Users

France
University of Zurich

Completed

Seated Evaluation of Anorectal funcTion by High Resolution Anorectal Manometry (SEAT)

Incontinence | Anismus

Switzerland
University of Florence

Unknown

Grazoprevir and Elbasvir Without Ribavirin for 12 Weeks in Patients With HCV-related Cryoglobulinemic Nephropathy (CRYOKID)

Hepatitis C | Cryoglobulinaemic Glomerulonephritis
Pfizer

Completed

Clinical Study to Evaluate Pharmacokinetics and Safety of PF-06700841 After Single and Multiple Oral Doses as Modified Release Formulations

Healthy Participants

United States
Cedars-Sinai Medical Center

Completed

Identification of Adverse Plaque Characteristics by Coronary MR Angiography

Coronary Artery Disease

United States

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