Search clinical trials for: Discontinue methotrexate

Total 1546 results

University of Michigan Rogel Cancer Center
GlaxoSmithKline

Terminated

Trial of Low-Dose Methotrexate and I 131 Tositumomab for Previously Untreated, Advanced-Stage, Follicular Lymphoma

Follicular Lymphoma

United States
Seoul National University Hospital

Completed

Comparison Study of Psoriasis Severity Assessment Tools

Psoriasis

Korea, Republic of
Jun Zhu

Unknown

MT-R Followed by Autologous Stem Cells Transplantation in Newly-diagnosed Primary Central Nervous System Lymphoma

Primary Central Nervous System Lymphoma

China
The Cleveland Clinic

Completed

Phase II Randomized Study of Glucocorticoids With or Without Methotrexate for Treatment of Giant Cell Arteritis

Giant Cell Arteritis
Merck KGaA, Darmstadt, Germany

Completed

Study of Therapeutic Options for Subjects Discontinuing Efalizumab and Experiencing Disease Recurrence

Psoriasis
Amgen

Completed

A Study of Cyclophosphamide/Methotrexate/5-Fluorouracil (CMF) With Pegfilgrastim in Subjects With Breast Cancer

Breast Cancer
National Institute of Allergy and Infectious Diseases...

Completed

Steroids and Methotrexate to Treat Systemic Vasculitis

Inflammation | Vasculitis | Wegener's Granulomatosis

United States
Tehran University of Medical Sciences

Active, not recruiting

Assessment of the Efficacy of Letrozole in the Treatment of Ectopic Pregnancy

Ectopic Pregnancy

Iran, Islamic Republic of
AbbVie

Completed

A Study Comparing Upadacitinib (ABT-494) Monotherapy to Methotrexate (MTX) Monotherapy in Adults With Rheumatoid Arthritis (RA) Who Have an Inadequate Response to MTX (SELECT-MONOTHERAPY)

Rheumatoid Arthritis

United States, Argentina, Australia, Austria, Belgium, Bulgaria, Chile, Czechia, Estonia, Greece, Hungary, Israel, Italy, Japan, Mexico, Poland, Portugal, Puerto Rico, Romania, Russian Federation, Serbia, South Africa, Spain, Turkey, Uk...
Assistance Publique Hopitaux De Marseille

Active, not recruiting

Multicenter Randomized Double Blind Controlled-study to Assess the Potential of Methotrexate Versus Placebo to Improve and Maintain Response to Anti TNF- Alpha Agents in Adult Patients With Moderate to Severe Psoriasis (METHOBIO)

Psoriasis

France
University of North Carolina, Chapel Hill
Patient-Centered Outcomes Research Institute; National Institute of Arthritis... and other collaborators

Completed

Low Dose Oral Methotrexate in Pediatric Crohn's Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy (COMBINE)

Pediatric Crohn's Disease

United States
Institut Bergonié

Completed

PAZOPANIB Efficacy and Tolerance in Desmoids Tumors (DESMOPAZ)

Progressive Desmoids Tumors

France
Janssen Research & Development, LLC

Completed

An Efficacy And Safety Study of CNTO 6785 In Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy

Rheumatoid Arthritis

Poland, Argentina, Colombia, Philippines, Russian Federation, Thailand, Czech Republic
University of Roma La Sapienza

Unknown

Treatment of Reperfusion Event by Vitamin C Infusion (TREVI)

Angina Pectoris

Italy
National Heart, Lung, and Blood Institute (NHLBI)
National Cancer Institute (NCI); Blood and Marrow Transplant Clinical Trials...

Completed

Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

Lymphoma, Follicular | Lymphoma, B-Cell | Lymphoma, Large B-Cell, Diffuse | Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia | Acute Leukemia | Chronic Myelogenous Leukemia | Myelodysplasia | Small Lymphocytic Lymphoma

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Methotrexate Combined With Tofacitinib in Rheumatoid Arthritis

Rheumatoid Arthritis
University of Alabama at Birmingham

Not yet recruiting

Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant

Myeloproliferative Disorders | Acute Leukemia | Myelodysplastic Syndrome

United States
The First Affiliated Hospital of Soochow University
Zhongda Hospital; Suzhou Municipal Hospital; The First People's Hospital of Changzhou

Recruiting

Cladribine Combined With G-CSF and Cytarabine as a Salvage Treatment in R/R ALL

Acute Lymphoblastic Leukemia

China
PETHEMA Foundation

Recruiting

Protocol For the Treatment Acute Lymphoblastic Leukemia With Ph 'Negative in Elderly Patients (> 55 Years)

Acute Lymphoblastic Leukemia

Spain
Massachusetts General Hospital
Brigham and Women's Hospital; University of California, San Francisco; Harvard...

Completed

PET/CT Imaging Companion Study To ACTG A5314 (PET/CTMTX)

Inflammation | Atherosclerosis | HIV

United States
Tufts Medical Center

Completed

Mechanism of Action Study for Psoriasis (MOA)

Psoriasis

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S9716: Combination Chemotherapy in Treating Patients With Merkel Cell Cancer

Neuroendocrine Carcinoma of the Skin

United States
Fred Hutchinson Cancer Center

Completed

Graft-Versus-Host Disease Prevention in Treating Patients Who Are Undergoing Bone Marrow Transplantation

Lymphoma | Leukemia | Graft Versus Host Disease

United States
University of Parma

Unknown

Methotrexate as a Steroid-sparing Agent in Idiopathic Retroperitoneal Fibrosis: a Randomised, Multicenter Trial (FIPREDEX)

Idiopathic Retroperitoneal Fibrosis | Perianeurysmal Retroperitoneal Fibrosis | Chronic Periaortitis

Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Filgrastim-Treated Donor Peripheral Stem Cell Transplantation in Treating Patients With Acute Leukemia</p>

Leukemia

United States
Fred Hutchinson Cancer Center

Completed

Monoclonal Antibody Followed by Bone Marrow Transplantation in Treating Patients With Acute Myelogenous Leukemia in Remission or First Relapse

Leukemia
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Childhood Acute Myeloid Leukemia in Remission | Adult Acute Lymphoblastic Leukemia in Remission | Childhood Acute Lymphoblastic Leukemia in Remission | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent... and other conditions

United States
GOG Foundation
National Cancer Institute (NCI)

Completed

Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia

Hydatidiform Mole | Choriocarcinoma | FIGO Stage I Gestational Trophoblastic Tumor | FIGO Stage II Gestational Trophoblastic Tumor | FIGO Stage III Gestational Trophoblastic Tumor

United States, Korea, Republic of, Canada, Japan, United Kingdom
Stanford University
AstraZeneca

Terminated

Durvalumab and Standard Chemotherapy Before Surgery in Treating Patients With Variant Histology Bladder Cancer

Bladder Adenocarcinoma | Bladder Mixed Adenocarcinoma | Bladder Squamous Cell Carcinoma | Infiltrating Bladder Urothelial Carcinoma With Giant Cells | Infiltrating Bladder Urothelial Carcinoma, Nested Variant | Infiltrating Bladder Urothelial Carcinoma, Plasmacytoid Variant | Bladder Urothelial... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Allogeneic Stem Cell Transplant for CLL

Chronic Lymphocytic Leukemia | Prolymphocytic Leukemia | Richter Syndrome | Allogeneic Hematopoietic Stem Cell Transplantation Recipient

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Chemotherapy and Bone Marrow Transplantation in Treating Patients Acute Myeloid With Leukemia or Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia

United States
Kufa University

Completed

Effect of Low Doses of Vitamin C on Salivary Cortisol , Heart Rate , Blood Pressure During Group Presentation

Stress, Psychological

Iraq
Gustave Roussy, Cancer Campus, Grand Paris
Children's Oncology Group

Unknown

Intergroup Randomized Trial for Children or Adolescents With B-Cell Non Hodgkin Lymphoma or B-Acute Leukemia: Rituximab Evaluation in High Risk Patients

B-cell Non Hodgkin Lymphoma | Mature B-cell Leukemia Burkitt-type

Belgium, France, United Kingdom, Netherlands, Canada, Hungary, Italy, Poland, Spain, China
Sun Yat-sen University

Unknown

The GD-2008 ALL Protocol for Childhood Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

China
European Organisation for Research and Treatment...

Completed

Combination Chemotherapy With Trastuzumab in Treating Women With Metastatic Breast Cancer

Breast Cancer

Belgium, Netherlands, France, Egypt, South Africa, United Kingdom, Denmark, Serbia, Poland
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Prevention of Graft-Versus-Host Disease in Patients With Hematologic Malignancies Who Are Receiving a Bone Marrow Transplant

Myelodysplastic Syndromes | Leukemia | Graft Versus Host Disease
Centocor, Inc.
Schering-Plough

Completed

An Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate Therapy

Arthritis, Rheumatoid

Australia, Poland, Ukraine, United States, Argentina, Colombia, Mexico, Korea, Republic of, Malaysia, Russian Federation, New Zealand, Hungary, Lithuania
University of Chicago
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Stage IV Locally Advanced or Metastatic Bladder Cancer

Bladder Cancer

United States
Taiho Pharmaceutical Co., Ltd.

Completed

A Randomized Controlled Study of Postoperative Adjuvant Therapy of Uracil-tegafur (UFT) Compared With Cyclophosphamide/Methotrexate/5-fluorouracil (CMF) in Breast Cancer (NSAS-BC)

Breast Cancer

Japan
Pacira Pharmaceuticals, Inc

Completed

DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor

Meningeal Neoplasms

United States, Canada
Won Seog Kim
Celltrion

Recruiting

[CREMA]Combination of R-M Followed by R-A in Elderly Patients With Primary CNS Lymphoma

Primary CNS Lymphoma

Korea, Republic of
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0535, Gemtuzumab and Combination Chemotherapy in Treating Patients With Previously Untreated Acute Promyelocytic Leukemia

Leukemia

United States
University Hospital, Montpellier

Completed

Topical Steroids Alone or Associated With Methotrexate in Bullous Pemphigoid (BP/MTX)

Bullous Pemphigoid

France
Children's Hospital of Philadelphia
Gateway for Cancer Research

Completed

Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy

Osteosarcoma | Nephrotoxicity | Ototoxicity

United States
UCB Pharma SA
Parexel

Completed

Study to Assess the Short- and Long-term Efficacy of Certolizumab Pegol Plus Methotrexate Compared to Adalimumab Plus Methotrexate in Subjects With Moderate to Severe Rheumatoid Arthritis (RA) Inadequately Responding to Methotrexate

Rheumatoid Arthritis

Romania, United States, Australia, Austria, Bulgaria, Canada, Czechia, France, Germany, Greece, Hungary, Ireland, Italy, Mexico, Monaco, Poland, Portugal, Spain, Switzerland, United Kingdom
Ohio State University Comprehensive Cancer Center

Completed

Safety & Efficacy of Atorvastatin for Prophylaxis of Acute Graft Versus Host Disease in Patients With Hematological Malignancies HLA- Donor Hematopoietic Stem Cell Transplantation

Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia

United States
University Health Network, Toronto
Bayer

Completed

Alemtuzumab and Cyclosporine for the Prevention of Graft vs Host Disease After Stem Cell Transplants

Bone Marrow Transplantation | Graft Versus Host Disease

Canada
Karolinska Institutet

Completed

Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell Transplantation

Survival | Graft-versus-host Disease

Sweden
Children's Oncology Group
National Cancer Institute (NCI); Children's Cancer Group

Completed

Vinblastine and Methotrexate in Treating Children With Desmoid Tumors

Desmoid Tumor

United States, Australia, Canada
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI)

Completed

Interleukin-2 Gene or Methotrexate in Treating Patients With Recurrent or Refractory Stage III or Stage IV Head and Neck Cancer

Head and Neck Cancer

United States

Search clinical trials for: Discontinue methotrexate

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