Search clinical trials for: Durvalumab/Tremelimumab in neoadjuvant and Durvalumab in adjuvant setting

Total 564 results

Seoul National University Hospital

Active, not recruiting

Durvalumab(MEDI4736)/Tremelimumab in Combination With Gemcitabine/Cisplatin in Chemotherapy-naïve Biliary Tract Cancer

Biliary Tract Neoplasms

Korea, Republic of
National Cancer Institute (NCI)

Completed

Immune Checkpoint Inhibition (Tremelimumab and/or MEDI4736) in Combination With Radiation Therapy in Patients With Unresectable Pancreatic Cancer

Pancreatic Neoplasms | Pancreatic Cancer | Pancreas Cancer | Cancer of Pancreas | Cancer of the Pancreas

United States
Anna Olczak

Completed

Importance of Core Stability for Coordinated Movement of the Human Body in Stroke Rehabilitation

Stroke

Poland
Assiut University

Not yet recruiting

BRCA 1/2 Status as a Predictive Factor to Response to Platinum Based Chemotherapy in Cancer Ovary

Ovarian Cancer
National Cancer Institute (NCI)

Completed

A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination With Immune Checkpoint Inhibition in Refractory Colorectal Cancer

Colorectal Neoplasms | Colorectal Cancer | Colorectal Carcinoma | Colorectal Adenocarcinoma | Refractory Cancer

United States
AIO-Studien-gGmbH
AstraZeneca

Completed

Durvalumab and Tremelimumab With Gemcitabine or Gemcitabine/Cisplatin Compared to Gemcitabine/Cisplatin in CCA Patients (IMMUCHEC)

Cholangiocarcinoma | Cholangiocarcinoma Non-resectable | Gall Bladder Carcinoma | Gallbladder Carcinoma Non-Resectable

Germany
Sidney Kimmel Comprehensive Cancer Center at Johns...
AstraZeneca

Active, not recruiting

CTLA-4 /PD-L1 Blockade Following Transarterial Chemoembolization (DEB-TACE) in Patients With Intermediate Stage of HCC (Hepatocellular Carcinoma) Using Durvalumab and Tremelimumab

Hepatocellular Carcinoma | Intermediate Stage of Hepatocellular Carcinoma

United States
National Cancer Institute (NCI)

Completed

A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)

Hepatocellular Carcinoma | Cholangiocarcinoma | Bile Duct Cancer | Biliary Tract Neoplasms | Liver Cancer

United States
Institut Català d'Oncologia
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; University of Aberdeen and other collaborators

Unknown

Environmental Assessment of Secondhand Smoke Exposure in Private Settings and Outdoor Settings in Europe

Second Hand Tobacco Smoke

Spain
Assistance Publique - Hôpitaux de Paris

Recruiting

Does Position Influence the Diagnosis of Detrusor Overactivity in a Neurological Population (Cysto-position)

Neurologic Disorder | Urodynamic Exam

France
Kyoto Breast Cancer Research Network

Terminated

Anti PD-L1 Antibody + Anti CTLA-4 Antibody in Combination With Hormone Therapy in Patients With Hormone Receptor Positive HER2-negative Recurrent or Metastatic Breast Cancer

Breast Cancer

Japan
Georgetown University
AstraZeneca

Recruiting

Neoadjuvant Tremelimumab and Durvalumab With Gem/Cis in Intrahepatic Cholangiocarcinoma (ESR-22-21719)

Biliary Tract Cancer | Borderline Resectable Carcinoma

United States
Association Pour La Recherche des Thérapeutiques...

Active, not recruiting

NEoadjuvant Dose-dense MVAC In cOmbination With Durvalumab and Tremelimumab in Muscle-invasive Urothelial Carcinoma (NEMIO)

Infiltrating Bladder Urothelial Carcinoma

France
Anna Olczak

Completed

Passive Stabilization of the Trunk and Upper Arm in Hand Rehabilitation After Stroke

Stroke

Poland
Anna Olczak

Completed

Age and Body Position on Handgrip Strength and Movement Coordination of Upper Limb

Stroke

Poland
Anna Olczak

Completed

Motor Coordination and Grip Strength of the Dominant and Non-dominant Hand and Wrist in Post-stroke Patients.

Stroke

Poland
AstraZeneca

Active, not recruiting

AZD9291 in Combination With Ascending Doses of Novel Therapeutics

Advanced Non Small Cell Lung Cancer

Canada, Poland, Taiwan, United States, Korea, Republic of, Japan, Russian Federation, Ukraine
Bayer

Recruiting

An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery (REFINE-IO)

Unresectable Hepatocellular Carcinoma

Greece, Spain, Brazil, China, Colombia, Italy, Saudi Arabia, Taiwan, Thailand, United States, Korea, Republic of, Argentina, France, Mexico, Turkey
Biofourmis Singapore Pte Ltd.
Mundipharma Research Limited

Completed

Continuous Monitoring of Physiology and Self-reported Pain Score Amongst Post-surgical Knee Patients (ObservePAIN)

Knee Arthroplasty

Singapore
Technical University of Munich
German Cancer Aid

Recruiting

Respiratory Training and Relaxation Techniques to Improve Adjuvant Radiation Therapy in DIBH in Breast Cancer (B-REST)

Breast Cancer | Radiotherapy | Relaxation | Breathholding

Germany
University of Oxford
European and Developing Countries Clinical Trials Partnership (EDCTP); Kenya...

Completed

A Study to Determine if a New Malaria Vaccine is Safe and Induces Immunity Among Kenyan Adults, Young Children and Infants

Malaria,Falciparum

Kenya
AstraZeneca

Active, not recruiting

Study of Durvalumab Given With Chemotherapy, Durvalumab in Combination With Tremelimumab Given With Chemotherapy, or Chemotherapy in Patients With Unresectable Urothelial Cancer (NILE)

Metastatic Urothelial Cancer | Unresectable Locally Advanced Urothelial Cancer

United States, Italy, Spain, Canada, Hungary, Poland, Argentina, Thailand, Vietnam, Turkey, Korea, Republic of, Brazil, Czechia, India, Japan, Philippines, Russian Federation, China, Taiwan, Israel, Australia, Bulgaria
MedImmune LLC

Active, not recruiting

A Study of Durvalumab or Tremelimumab Monotherapy, or Durvalumab in Combination With Tremelimumab or Bevacizumab in Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma

United States, Italy, Spain, Taiwan, Korea, Republic of, China, Hong Kong, Japan, Singapore
University of Wisconsin, Madison
AstraZeneca

Terminated

Phase Ib Study of Stereotactic Body Radiotherapy (SBRT) in Oligometastatic Non-small Lung Cancer (NSCLC) With Dual Immune Checkpoint Inhibition

Non-small Cell Lung Cancer | Non-small Cell Lung Cancer Stage IV

United States
AstraZeneca

Active, not recruiting

Phase III Open Label First Line Therapy Study of MEDI 4736 (Durvalumab) With or Without Tremelimumab Versus SOC in Non Small-Cell Lung Cancer (NSCLC) (MYSTIC)

Non-Small-Cell Lung Carcinoma NSCLC

United States, Belgium, Spain, Canada, Taiwan, Thailand, Vietnam, France, Germany, Italy, Korea, Republic of, Hungary, Japan, Russian Federation, Netherlands, Australia, Switzerland
Insel Gruppe AG, University Hospital Bern
Swiss Cancer League

Not yet recruiting

Safety of Biliary Intraductal Radiofrequency Ablation in Patients With Unresectable Extrahepatic Biliary Tract Cancer (Ablatio)

Bile Duct Cancer

Switzerland
Eye & ENT Hospital of Fudan University
Changhai Hospital; Shanghai Zhongshan Hospital; Fujian Medical University Union... and other collaborators

Not yet recruiting

Neoadjuvant vs Adjuvant in Locally Advanced Recurrent NPC

Recurrent Nasopharyngeal Carcinoma

China
Canadian Cancer Trials Group
AstraZeneca

Recruiting

A Phase II Study of Durvalumab Treatment - Substudy A: In Patients Who Discontinued Prior Checkpoint Therapy Due to Immune Related Toxicity - Substudy B: For Continued Treatment (+/- Tremelimumab) of Patients Previously Enrolled to Completed CCTG Studies

Cancer

Canada
University Health Network, Toronto

Recruiting

Personalized Patient Derived Xenograft (pPDX) Modeling to Test Drug Response in Matching Host (REFLECT)

Breast Cancer | Breast Neoplasms | Colorectal Neoplasms | Colorectal Cancer | Ovarian Cancer | Ovarian Neoplasm

Canada
AstraZeneca

Completed

Phase III Open Label Study of MEDI 4736 With/Without Tremelimumab Versus Standard of Care (SOC) in Recurrent/Metastatic Head and Neck Cancer (KESTREL)

Squamous Cell Carcinoma of the Head and Neck

United States, Canada, France, Italy, Spain, United Kingdom, Poland, Taiwan, Thailand, Vietnam, Belgium, Germany, Korea, Republic of, Brazil, India, Japan, Philippines, Russian Federation, Austria, Ukraine, Greece, Slovakia, Romania
University of Latvia
University of Ulm; Universitaet Innsbruck

Recruiting

Hybrid-sensor Breath Analysis for Colorectal Cancer Screening (HYCOR)

Colorectal Cancer | Polyp of Colon

Latvia
Ludwig Institute for Cancer Research
Cancer Research Institute, New York City; MedImmune LLC

Completed

A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers

Melanoma | Sarcoma | Breast Cancer | Solid Tumor | Prostate Cancer | Bladder Cancer | Head and Neck Squamous Cell Carcinoma | Cutaneous T-Cell Lymphoma | Renal Cancer | Merkel Cell Carcinoma | Testicular Cancer

United States
National Cancer Institute (NCI)

Recruiting

Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects With Hepatocellular Carcinoma or Biliary Tract Carcinoma

Hepatocellular Carcinoma | Hepatocellular Cancer | Metastatic Hepatocellular Carcinoma

United States
Centre Hospitalier Universitaire de Saint Etienne

Completed

Body Perception and Complex Regional Pain Syndrome (SDRC)

Complex Regional Pain Syndromes

France
AstraZeneca

Active, not recruiting

Study of Durvalumab With Tremelimumab Versus SoC as 1st Line Therapy in Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE) (NEPTUNE)

Non Small Cell Lung Carcinoma NSCLC

Denmark, United Kingdom, United States, Poland, Brazil, India, Japan, Mexico, Peru, Russian Federation, Turkey, China, Malaysia, Hong Kong, Korea, Republic of, Chile, Israel, Ukraine, Portugal, Greece, Bulgaria, Philippines, Sweden, A... and more
Hopital Foch

Completed

Is Routine Postoperative Oxygen Therapy Still Necessary in 2020? (FreeO2)

Postoperative Oxygen Therapy

France
The Miriam Hospital

Completed

Weight Gain Prevention

Weight Gain

United States
Universidad de Zaragoza

Completed

Effects of Grade III Traction-mobilization in End-range Joint Position in Patients With Hip Osteoarthritis

Osteoarthritis, Hip

Spain
Wuhan Union Hospital, China

Not yet recruiting

Molecular Study and Precision Medicine for Colorectal Cancer (MSPM)

Recurrent Colorectal Carcinoma | Advanced Colorectal Carcinoma

China
Technische Universität Dresden
Deutsches Krebsforschungszentrum (DKFZ)

Recruiting

Response Prediction of Hyperthermic Intraperitoneal Chemotherapy in Gastro- Intestinal Cancer (Hi-STEP1)

Gastric Cancer | Colon Cancer | Peritoneal Carcinomatosis

Germany
University of Missouri-Columbia

Completed

Effects of Walking and Heating on Vascular Function in Diabetic Patients

Obesity | Type 2 Diabetes Mellitus

United States
AstraZeneca

Recruiting

Evaluate Durvalumab and Tremelimumab +/- Lenvatinib in Combination With TACE in Patients With Locoregional HCC (EMERALD-3)

Hepatocellular Carcinoma

Spain, Canada, Germany, Belgium, United States, France, Italy, Japan, China, Egypt, India, Russian Federation, Taiwan, Vietnam, Thailand, Saudi Arabia, Portugal, Korea, Republic of, Brazil, Malaysia, Mexico, Philippines, Puerto Rico
Second Affiliated Hospital, School of Medicine,...

Active, not recruiting

Efficacy and Safety of Immunotherapy Combined With Neoadjuvant Chemotherapy in Patients With Locally Advanced HPV (-) Head and Neck Squamous Cell Carcinoma: a Phase II Clinical Trial

Efficacy and Safety of Immunotherapy Combined With Neoadjuvant Chemotherapy in Patients With Locally Advanced HPV (-) HNSCC

China
Charite University, Berlin, Germany

Completed

Comparison of Pre-hospital and In-hospital Iv-tPA Stroke Treatment

Ischemic Stroke

Germany
Yunnan Cancer Hospital
Beijing Bethune Charitable Foundation

Recruiting

Single-arm, Single-center, Exploratory Phase II Clinical Study of Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer (ESTIMATE)

Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer

China
Canadian Cancer Trials Group
AstraZeneca

Active, not recruiting

Gemcitabine and Nab-Paclitaxel vs Gemcitabine, Nab-Paclitaxel, Durvalumab and Tremelimumab as 1st Line Therapy in Metastatic Pancreatic Adenocarcinoma

Pancreatic Adenocarcinoma

Canada
The Netherlands Cancer Institute
AstraZeneca

Active, not recruiting

Improve Checkpoint-blockade Response in Advanced Urothelial Cancer (ICRA)

Urothelial Carcinoma

Netherlands
The Netherlands Cancer Institute
AstraZeneca

Unknown

Assess the Safety of Immunotherapy Induction With Tremelimumab and Durvalumab Prior to Chemoradiotherapy and/or Resection in the Treatment (Induction)

Stage III NSCLC

Netherlands
Military Institute of Medicine, Poland

Completed

Positioning the Trunk and Upper Limb to Improve the Coordination of the Hand Movement After Stroke

Stroke

Poland
Institute of Medical Biology, Chinese Academy of...
Guangxi Center for Disease Control and Prevention

Completed

A Phase II, Safety and Efficacy Study of Inactivated EV 71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Infants

The Study Focused on the Safety of Inactivated EV71 Vaccine (Human Diploid Cell) Against Hand, Foot and Mouth Disease in Chinese Children and Infants

China

Search clinical trials for: Durvalumab/Tremelimumab in neoadjuvant and Durvalumab in adjuvant setting

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