Search clinical trials for: E10030 sham intravitreal injection

Total 469 results

Hemera Biosciences

Withdrawn

Intravitreal AAVCAGsCD59 for Advanced Dry Age-related Macular Degeneration (AMD) With Geographic Atrophy (GA)

Geographic Atrophy | Dry Age-related Macular Degeneration | Gene Therapy | Intravitreal Injection
Ophthotech Corporation

Terminated

A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® Monotherapy

Age-Related Macular Degeneration

Italy, Canada, Switzerland, United States, United Kingdom, Austria, Belgium, Brazil, Czechia, Estonia, Latvia, Poland, Slovakia
Ophthotech Corporation

Terminated

A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® Monotherapy

Age-Related Macular Degeneration

Israel, United States, Germany, Denmark, France, Turkey, Hungary, Colombia, Australia, Argentina, Spain
ProQR Therapeutics

Active, not recruiting

Study to Evaluate the Efficacy Safety and Tolerability of Ultevursen in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Sirius)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, Netherlands, United Kingdom, Germany
ProQR Therapeutics

Terminated

Study to Evaluate the Efficacy Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene With Early to Moderate Vision Loss (Celeste)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, United Kingdom
Santen Inc.

Terminated

LUMINA Phase III Study Assessing the Efficacy and Safety of Intravitreal Injections of 440 ug DE-109 Sirolimus for the Treatment of Active, Non-Infectious Uveitis of the Posterior Segment of the Eye

Non Infectious Uveitis

United States, India, Italy, Argentina
Jeffrey S Heier
Kato Pharmaceuticals, Inc.

Completed

A Safety and Efficacy Assessment of Resolvine for Treatment of Vitreomacular Attachment

Vitreomacular Traction | Vitreomacular Adhesion | Vitreomacular Attachment

United States
ProQR Therapeutics

Completed

Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Stellar)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, Canada, France
Indonesia University
Bayer

Completed

Early Anatomical, Physiological, and Clinical Changes in Diabetic Macular Edema After Intravitreal Aflibercept Injection

Diabetic Retinopathy | Diabetic Macular Edema | Clinically Significant Macular Edema

Indonesia
Second Affiliated Hospital of Xi'an Jiaotong University

Completed

The Effect of Conbercept Injection Through Different Routes for Neovascular Glaucoma

Neovascular Glaucoma

China
Afyonkarahisar Health Sciences University

Completed

Effect of Music Intervention on Intravitreal Injection

Music Intervention

Turkey
M. Ali Khan, MD
University of California, Los Angeles; Southeastern Retina Associates; Eye Associates...

Recruiting

Intravitreal Aflibercept for the Prevention of Proliferative Vitreoretinopathy Following Retinal Detachment Repair (PREVENT-PVR)

Proliferative Vitreoretinopathy | Retinal Detachment With Multiple Breaks, Unspecified Eye

United States
GenSight Biologics

Completed

RESCUE and REVERSE Long-term Follow-up (RESTORE)

Leber Hereditary Optic Neuropathy

United States, France, Italy, United Kingdom, Germany
Peregrine Eye and Laser Institute

Completed

Time Efficiency Comparison of Two IntraVitreal Injection Techniques (TIVI)

Diabetic Macular Edema | Choroidal Neovascularization | Neovascular Age-related Macular Degeneration | Uveitic Macular Edema | Retinal Vein Occlusion With Macular Edema

Philippines
Eye & ENT Hospital of Fudan University

Unknown

Prophylactic Effect of Conbercept Intravitreal Injection at the Conclusion of Cataract Surgery for Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema | Cataract Diabetic
Benha University

Recruiting

BEOVU Versus Eylea in the Treatment of Diabetic Macular Edema

Macular Edema

United Arab Emirates
Instituto Universitario de Oftalmobiología Aplicada...

Completed

Safety and Effectiveness of Bevacizumab Intravitreal Injections in the Treatment of Macular Edema Secondary to Retinal Vein Occlusion (EBOVER)

Macular Edema | Retinal Vein Occlusion

Spain
Xun Xu
Peking University; Zhongshan Ophthalmic Center, Sun Yat-sen University; Air Force... and other collaborators

Unknown

Pharmacogenomic Study on Anti-VEGF Medicine in Treatment of Macular Neovascular Diseases

Age-Related Macular Degeneration | Polypoidal Choroidal Vasculopathy | Pathological Myopia | Conbercept | Pharmacogenomic

China
Chengdu Kanghong Biotech Co., Ltd.
Beijing DMS Pharma Ltd.; The Digital Angiography Reading Center (DARC)

Completed

A Randomized, Double-masked, Multicenter, Controlled Study of Intravitreal KH902 in Patients With Neovascular AMD (AURORA)

Neovascular Age-related Macular Degeneration

China
Instituto Universitario de Oftalmobiología Aplicada...
University of Valladolid

Active, not recruiting

Safety Assessment of Intravitreal Mesenchymal Stem Cells for Acute Non Arteritic Anterior Ischemic Optic Neuropathy (NEUROSTEM)

Non Arteritic Ischemic Optic Neuropathy

Spain
Chengdu Kanghong Biotech Co., Ltd.
University of Wisconsin, Madison; Air Force Military Medical University, China

Completed

A Study Assessing the Safety and Efficacy of Multiple Intravitreal KH902 in Patients With CNV Due to AMD (HOPE)

Neovascular Age-related Macular Degeneration

China
iCo Therapeutics Inc.

Completed

Safety Study of iCo-007 Intravitreal Injection to Treat Diabetic Macular Edema

Diffuse Diabetic Macular Edema

United States
Perfuse Therapeutics, Inc.

Recruiting

A Study of PER-001 in Participants With Diabetic Retinopathy

Diabetic Retinopathy

United States
Perfuse Therapeutics, Inc.

Recruiting

A Study of PER-001 in Participants With Open-Angle Glaucoma

Open-angle Glaucoma

United States
Merck Sharp & Dohme LLC

Terminated

Study to Treat Uveitis Associated Macular Edema

Uveitis | Cystoid Macular Edema
Merck Sharp & Dohme LLC

Completed

A Study in Subjects With Retinal Detachment

Retinal Detachment
Merck Sharp & Dohme LLC

Terminated

Study of Denufosol (INS37217) in Subjects With Rhegmatogenous Retinal Detachment

Retinal Detachment

United States
Merck Sharp & Dohme LLC

Withdrawn

A Study of Denufosol Tetrasodium Intravitreal Injection in Subjects With Post Cataract Extraction Macular Edema

Macular Edema, Cystoid
Innovent Biologics (Suzhou) Co. Ltd.

Suspended

Evaluation of IBI302 Injection in nAMD or DME

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

China
Rudolf Foundation Clinic

Completed

The ROVO Study: Radial Optic Neurotomy for CVO

Central Retinal Vein Occlusion

Austria
University of Leipzig

Unknown

Influence of Systemic Parameters in Diabetic Macular Edema - LIPSIA Study

Diabetic Macular Edema | Macular Edema | Retinal Vein Occlusion

Germany
Prince of Songkla University

Recruiting

Intracameral Versus Intravitreal Bevacizumab Injection in NVG: RCT

Glaucoma, Neovascular | Vascular Endothelial Growth Factor Overexpression

Thailand
ONL Therapeutics

Completed

A Study to Evaluate the Safety and Tolerability of ONL1204 in Patients With Macula-off, Rhegmatogenous Retinal Detachment

Rhegmatogenous Retinal Detachment - Macula Off

Australia
Instituto Universitario de Oftalmobiología Aplicada...

Completed

Initial Treatment With Bevacizumab in Choroidal Neovascularization Associated to High Myopia (BENEMCOR)

Choroidal Subfoveal/Juxtafoveal Neovascularization in High Myopia

Spain
GenSight Biologics

Completed

Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation (RESCUE)

Optic, Atrophy, Hereditary, Leber

United Kingdom, United States, France, Germany, Italy
Jeffrey S Heier
Regeneron Pharmaceuticals

Unknown

IAI Versus Sham as Prophylaxis Against Conversion to Neovascular AMD (PRO-CON)

Age-Related Macular Degeneration

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Atrophic Age-related Macular Degeneration (AMD) Treated With Intravitreal Injections of Umbilical Cord Blood Platelet-rich Plasma (CB-PRP): a Pilot Study (CORD-IV)

Dry Age-related Macular Degeneration

Italy
Ophthotech Corporation

Terminated

A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Either Avastin® or Eylea® Compared to Avastin® or Eylea® Monotherapy

Age-Related Macular Degeneration

France, Israel, Italy, United States, Spain, Portugal, Germany, Austria, Canada, Czechia, Estonia, Latvia, Poland, Slovakia, Australia, Hungary, Croatia, Argentina, Finland, Brazil, Colombia, Norway
University of Oxford
Pfizer

Completed

Intravitreal Macugen for Ischaemic Diabetic Macular Oedema (MIDME)

Diabetic Macular Oedema

United Kingdom
GenSight Biologics

Completed

Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation (REVERSE) (REVERSE)

Optic, Atrophy, Hereditary, Leber

United Kingdom, United States, Germany, Italy, France
University Hospital, Bordeaux

Completed

Assessment of Early Changes in SD-OCT After Initiation of a Treatment by Intravitreal Aflibercept (EYLEA®)START (START)

Neovascular Age-related Macular Degeneration of All Subtypes

France
Asociación para Evitar la Ceguera en México

Unknown

Bevacizumab and Retinal Vascular Occlusions

Vascular Occlusion | Edema Macular

Mexico
Oslo University Hospital

Completed

Plasma Levels of Vascular Endothelial Growth Factor Before and After Intravitreal Injection of Aflibercept (Eylea-2014)

Exudative Age-related Macular Degeneration
Asociación para Evitar la Ceguera en México

Unknown

Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural Outcome

Retinopathy of Prematurity

Mexico
Chengdu Kanghong Biotech Co., Ltd.

Terminated

Efficacy and Safety Trial of Conbercept Intravitreal Injection for Neovascular AMD (PANDA-1)

Neovascular Age-related Macular Degeneration

United States, Argentina, Australia, Austria, Belgium, Canada, Chile, Colombia, Germany, Hong Kong, Lithuania, Mexico, Netherlands, New Zealand, Peru, Philippines, Poland, Portugal, Singapore, Spain, Switzerland, Taiwan
Chengdu Kanghong Biotech Co., Ltd.

Terminated

Efficacy and Safety Trial of Conbercept Intravitreal Injection for Neovascular AMD (PANDA-2)

Neovascular Age-related Macular Degeneration

United States, Bulgaria, China, Czechia, Denmark, France, Hungary, Israel, Italy, Latvia, Slovakia, United Kingdom
Asan Medical Center

Completed

Efficacy and Safety of Intravitreal Aflibercept Injection for Subacute Central Serous Chorioretinopathy

Central Serous Chorioretinopathy

Korea, Republic of
The University of Texas Medical Branch, Galveston

Recruiting

Intravitreal Injection Site and Perceived Pain

Pain

United States
Peking Union Medical College Hospital
Beijing Bethune public welfare fund

Terminated

Effects of Conbercept in Refractory Uveitic Macular Edema and VEGF

Uveitis | Macular Edema | Vascular Endothelial Growth Factor | Effect of Drugs

China
The Jerzy Kukuczka Academy of Physical Education...
Universitätsklinikum Hamburg-Eppendorf

Completed

Tactile Acuity in Experimentally Induced Acute Low Back Pain

Low Back Pain | Acute Pain

Poland

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