Search clinical trials for: Endothelin-3

Total 8163 results

Actelion

Completed

Open-label Study With Bosentan in Interstitial Lung Disease (BUILD 2 OL)

Interstitial Lung Disease | Scleroderma

United States, Korea, Republic of, Israel, France, United Kingdom, Netherlands, Switzerland, Germany, Canada, Italy, Sweden
General Hospital of Chalkida

Unknown

Bosentan for Severe Mitral Valve Dysfunction (BOSMIVAR)

SECONDARY PULMONARY HYPERTENSION | MITRAL STENOSIS | CHILDHOOD RHEUMATOID FEVER | CONGESTIVE HEART FAILURE

Greece
Rikshospitalet University Hospital

Terminated

Treatment of Early Systemic Sclerosis by Bosentan (TRANOS)

Systemic Sclerosis (Scleroderma)

Norway
Tufts University
Massachusetts General Hospital

Withdrawn

Endothelial Cell Gene Networks of CVD

Coronary Heart Disease

United States
Assiut University

Not yet recruiting

Evaluation of Serum Tumor Endothelial Marker1 as a Potential Biomarker for Colorectal Cancer Diagnosis and Cancer Progression

Colorectal Cancer
Groupe Hospitalier Paris Saint Joseph

Withdrawn

Study Comparing the Kinetics of Endothelial Cell Loss Associated With the XEN® Implant Versus Traditional Filtering Surgery for Glaucoma (CINEXEN)

Glaucoma
Erasme University Hospital
Fonds National de la Recherche Scientifique; Fonds Erasme; Fonds pour la chirurgie...

Completed

Uric Acid Metabolism, Endothelial Function and Oxidative Stress in Vegans and Omnivores.

Healthy | Diet Modification

Belgium
Eastern Mediterranean University

Completed

Effect Of Meal Frequency On Weight Loss And Body Composition Of Obese And Overweight Women

Overweight and Obesity

Cyprus
PharmaMar

Recruiting

Study to Evaluate the Effect of Bosentan on the Pharmacokinetics of Lurbinectedin in Patients With Advanced Solid Tumors

Advanced Solid Tumor

Spain
Pfizer

Completed

Pilot Chart Review Study Of Sitaxentan Sodium (Thelin) In Patients With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension
Rajan Saggar
Actelion

Withdrawn

Pulmonary Arterial Hypertension Secondary to Idiopathic Pulmonary Fibrosis and Treatment With Bosentan

Idiopathic Pulmonary Fibrosis | Pulmonary Arterial Hypertension

United States
Actelion

Completed

Pulmonary Artery Remodelling With Bosentan

Hypertension, Pulmonary

Australia
UConn Health
Actelion

Terminated

Bosentan for Poorly Controlled Asthma

Asthma

United States
Encysive Pharmaceuticals

Completed

Safety and Efficacy Study of Sitaxentan Sodium (Thelin™) in Patients With Pulmonary Arterial Hypertension

Pulmonary Hypertension

United States
VA Loma Linda Health Care System
Actelion

Completed

Effect of Bosentan on Exercise Capacity at High Altitude

Pulmonary Hypertension | Altitude

United States
Gilead Sciences

Completed

A Clinical Study to Evaluate the Effects of Darusentan on Safety and Efficacy in Subjects With Resistant Systolic Hypertension Receiving Combination Therapy With Three or More Blood Pressure Lowering Drugs

Hypertension
Universitair Ziekenhuis Brussel

Completed

Transcranial Doppler in Multiple Sclerosis (TRADOMS)

Multiple Sclerosis

Belgium
Elpen Pharmaceutical Co. Inc.

Completed

Bosentan Treatment of Digital Ulcers Related to Systemic Sclerosis (GRegistry SCDU)

Scleroderma | Digital Ulcer | Systematic Sclerosis

Greece
University Medical Center Groningen
Actelion

Completed

The Clinical And Subclinical Effects on Arterial Stiffness of Bosentan in Patients With Systemic Sclerosis (CEASESTIFF)

Scleroderma, Systemic

Netherlands
Berto J Bouma

Unknown

Bosentan Improves Clinical Outcome of Adults With Congenital Heart Disease or Mitral Valve Lesions Who Undergo CArdiac Surgery (BOCA)

Congenital Heart Disease

Netherlands
Karolinska Institutet
The Swedish Research Council; Actelion; Swedish Heart Lung Foundation

Completed

Effect of Bosentan on Endothelial Function in Patients With Type 2 Diabetes (BANDY)

Type 2 Diabetes Mellitus

Sweden
Actelion

Completed

Bosentan Effects in Inoperable Forms of Chronic Thromboembolic Pulmonary Hypertension

Chronic Thromboembolic Pulmonary Hypertension

Canada, Australia, Germany, United States, Italy, United Kingdom, Austria, Belgium, Czech Republic, France, Netherlands, Poland, Spain
Heinrich-Heine University, Duesseldorf

Completed

Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis

Systemic Scleroderma | Skin Fibrosis | Hand Functionality

Germany
Actelion

Completed

Open Label Extension Study in Patients With Idiopathic Pulmonary Fibrosis Who Completed Protocol AC-052-321/ BUILD 3 / NCT00391443 (BUILD OL)

Idiopathic Pulmonary Fibrosis

United States, France, Spain, Korea, Republic of, United Kingdom, Belgium, Japan, Australia, Canada, Czech Republic, Germany, Ireland, Israel, Italy, Switzerland
University of California, Los Angeles
Actelion

Completed

Endothelin Blockade in Patients With Single Ventricle Physiology

Congenital Heart Disease

United States
Actelion

Completed

Bosentan in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH) (BENEFIT OL)

Pulmonary Hypertension

United States, Canada, Australia, Germany, Italy, United Kingdom, France, Austria, Belgium, Czech Republic, Netherlands, Poland, Spain
Medical University of Graz
Actelion

Completed

Early Therapy of Pulmonary Arterial Hypertension

Systemic Sclerosis | Pulmonary Hypertension

Austria
Medical University of Vienna

Completed

Effects of Non-Specific Endothelin-A Receptor Blockade on Ocular Blood Flow in Patients With Glaucoma

Glaucoma | Blood Flow Velocity

Austria
Benha University

Completed

Assessment of Endocan Serum Levels in Patients With Behcet Disease

Behçet

Egypt
Edwards Lifesciences

Active, not recruiting

EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis (EARLY TAVR)

Heart Diseases | Aortic Stenosis, Severe

United States, Canada
Asociación para Evitar la Ceguera en México
Emmecell

Recruiting

Study to Assess Safety and Tolerability of EO2002

Cataract | Endothelial Cell Loss, Corneal

Mexico
Center for Health, Exercise and Sport Sciences,...

Completed

Characterization and Detection of Prolonged Endothelin Receptors Antagonists Administration (ERAATH)

Pulmonary Hypertension

Serbia
Rigshospitalet, Denmark
Aarhus University Hospital; Bispebjerg Hospital; Actelion

Completed

Study of Placebo or Bosentan to Treat Patients With Single Ventricle Physiology. (TEMPO)

Tricuspid Atresia | Hypoplastic Left Heart Syndrome | Other Specified Congenital Anomalies of Heart

Denmark, Sweden
University of Cincinnati
Actelion

Completed

Double Blind, Randomized Trial of Bosentan for Sarcoidosis Associated Pulmonary Hypertension (BOSAPAH)

Pulmonary Arterial Hypertension | Sarcoidosis

United States
Assistance Publique - Hôpitaux de Paris

Completed

Effects of Bosentan (Tracleer) in the Course of Pulmonary Artery Hypertension Induced by Hypoxia

Hypoxia-Induced Pulmonary Artery Hypertension

France
Hacettepe University

Completed

Investigation of Relationship Between Vascular Functions, Exercise Capacity, and Respiratory Functions in CF

Cystic Fibrosis

Turkey
Eye-yon Medical

Active, not recruiting

EndoArt® Implantation in Subjects With Chronic Corneal Edema

Corneal Edema

Israel, Georgia, Germany, India, France, Netherlands
AbbVie (prior sponsor, Abbott)

Completed

A Study of Atrasentan on Reducing Albuminuria in Type 2 Diabetic Nephropathy Treated With Renin-Angiotensin System Inhibitors

Diabetic Nephropathy | Chronic Kidney Disease

United States, Puerto Rico
University Hospital, Antwerp
Belgium Health Care Knowledge Centre

Recruiting

The Belgian Endothelial Surgical Transplant of the Cornea (BESTCornea)

Corneal Edema | Fuchs' Endothelial Dystrophy | Bullous Keratopathy | Pseudophakic Bullous Keratopathy | Corneal Endothelial Disorder

Belgium
Medical University of Vienna

Terminated

Bosentan for Treatment of Hepatopulmonary Syndrome in Patients With Liver Cirrhosis

Liver Cirrhosis | Hepatopulmonary Syndrome

Austria
Pfizer

Completed

Phase 1, Single and Multiple Doses Study of Sitaxentan in Japanese and Western Subjects

Healthy

United States
Competence Network for Congenital Heart Defects
German Federal Ministry of Education and Research; Actelion

Completed

Bosentan in Treatment of Pulmonary Arterial Hypertension

Eisenmenger Syndrome

Germany
University Hospital, Grenoble

Recruiting

ENDOTHELION Study Group: Effect of Bosentan in NAION Patients (ENDOTHELION)

Ischemic Optic Neuropathy

France
Actelion

Completed

FUTURE 3 Study Extension (FUTURE 3 Ext)

Pulmonary Arterial Hypertension

United States, Australia, Belarus, China, Czechia, France, Germany, Hungary, India, Israel, Italy, Mexico, Poland, Russian Federation, Serbia, South Africa, Spain, Ukraine
University Hospital, Rouen

Unknown

VASCULAR AND RENAL IMPACT OF ENDOTHELIN-1 RECEPTOR BLOCKADE IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION (ENDOTHELIN-2)

Resistant Hypertension
Daniel Doberer

Terminated

Safety and Efficacy Study of Bosentan in Progressive Pulmonary Sarcoidosis (BOPSAC)

Pulmonary Hypertension | Sarcoidosis

Austria
Gilead Sciences

Terminated

DORADO-EX: Long-Term Safety Extension Study to the Phase 3 DORADO Study (Protocol DAR-311) of Darusentan in Resistant Hypertension (Darusentan)

Hypertension

United States, Sweden, Argentina, Denmark, Brazil, Canada, France, United Kingdom
Actelion

Completed

Bosentan in Systemic Sclerosis (HOME)

Systemic Sclerosis | Digital Ulcers

Netherlands
Actelion

Terminated

Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients Diagnosed With Pulmonary Hypertension (PH) (ASSET-2)

Pulmonary Hypertension

United States, France, United Kingdom, Netherlands
Hamilton Health Sciences Corporation
Actelion

Unknown

A Study to Evaluate the Use of Bosentan in Patients With Exercise Induced Pulmonary Arterial Hypertension Associated With Connective Tissue Disease

Hypertension, Pulmonary | Connective Tissue Disease

Canada

Search clinical trials for: Endothelin-3

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