Search clinical trials for: Escherichia coli Endotoxin (LPS)

Total 112 results

Radboud University Medical Center
UMC Utrecht

Completed

The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells (LPS-BM)

Sepsis, Endotoxemia, Immunosuppression

Netherlands
Rigshospitalet, Denmark

Unknown

Study of Renal Blood Flow During Human Endotoxemia

Healthy | Type 2 Diabetes | Endotoxemia

Denmark
Medical University of Vienna

Completed

Effect of Retaron® on Oxygen Induced Retinal Vasoconstriction in LPS Induced Inflammatory Model in Humans

Healthy Subjects | Imparied Retinal Vascular Reactivity

Austria
University of Alabama at Birmingham
American Fibromyalgia Syndrome Association

Completed

The Innate Central Nervous System Immune Response to an Experimental Immune Challenge in People With Fibromyalgia

Fibromyalgia

United States
University of California, Los Angeles

Completed

An Inflammatory Challenge Using Endotoxin

Inflammatory Response | Alcohol Use Disorder | Craving | Depressed Mood

United States
Rigshospitalet, Denmark

Completed

Study of Gene Activity in Fat and Muscle in Diabetics and Healthy Controls

Healthy | Type 2 Diabetes | Endotoxemia

Denmark
National Jewish Health

Not yet recruiting

Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma (Nasal-LPS)

Asthma | Asthma; Eosinophilic

United States
John Sundy

Completed

Role of TLR4 in Environmental Asthma

Asthma

United States
Radboud University Medical Center

Completed

Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1α

Hypoxia | Hyperoxia | Normoxia

Netherlands
Medical University of Vienna

Completed

Effect of Antioxidants on Ocular Blood Flow, Endothelial Function, and Cytokine Levels in LPS Induced Inflammatory Model in Humans.

Retina | Regional Blood Flow | Endotoxin, Escherichia Coli

Austria
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Inflammation and the Metabolic Syndrome in Humans (LPS)

Metabolic Syndrome X

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults

Asthma | Rhinitis, Allergic, Perennial | Rhinitis, Allergic, Seasonal

United States
Medical University of Vienna

Completed

Effect of Antioxidants on Oxygen Induced Vasoconstriction in Lipopolysaccharide (LPS) Induced Inflammatory Model in Humans

Healthy

Austria
Penn State University
United States Department of Agriculture (USDA)

Completed

Safety and Feasibility of an Endotoxemia Model

Inflammation | Cardiovascular Disease

United States
Karolinska Institutet
The Swedish Research Council; University of California, San Francisco; Swedish... and other collaborators

Completed

Inflammation and Brain Function - Main Study

Sickness Behavior
John Sundy

Terminated

Genetics of Asthma - Bronchoscopy Studies

Healthy | Atopic Asthma

United States
Karolinska Institutet
The Swedish Research Council; University of California, San Francisco; Swedish... and other collaborators

Completed

Inflammation and Brain Function - Pilot Study

Sickness Behavior
Pfizer

Terminated

A Study To Evaluate The Safety And Effects On The Body Of An Investigational Drug Using An Endotoxin-Induced Inflammatory Response Model (POM)

Healthy

United States
Radboud University Medical Center

Completed

The Effects of Concentration/Meditation on the Innate Immune Response During Human Endotoxemia

Innate Immune Response

Netherlands
University of North Carolina, Chapel Hill
National Institute of Environmental Health Sciences (NIEHS)

Terminated

Response of Airway Cells to 20,000 EU of Endotoxin in Normal Adults

Healthy Controls

United States
Herlev Hospital

Unknown

Low-Dose Endotoxemia and the Acute Phase Response

Sepsis | Endotoxemia

Denmark
Karolinska Institutet
Danderyd Hospital

Completed

Endotoxin-induced Inflammatory and Behavioral Responses and Predictors of Individual Differences

Sickness Behavior
Radboud University Medical Center
Exponential Biotherapies Inc.

Completed

PK/PD of EA-230 During Endotoxemia

Endotoxemia | Systemic Inflammatory Response

Netherlands
Robert J Noveck, M.D.
Foundation for the National Institutes of Health

Completed

Dose-Related Inflammatory Effects of Intravenous Endotoxin in Humans

Healthy

United States
University of Aarhus

Completed

The Effects of Amino Acid Supplement During Acute Inflammation.

Metabolic Diseases | Inflammation | Febrile Illness Acute

Denmark
GlaxoSmithKline
Biomedical Advanced Research and Development Authority

Terminated

Effects of GSK2798745 on Alveolar Barrier Disruption in a Segmental Lipopolysaccharide (LPS) Challenge Model

Healthy Volunteers

Germany
Radboud University Medical Center

Completed

Effects of BCG on Immune Response

Sepsis

Netherlands
Patrick Wagner, MD, FACS
List Biological Laboratories, Inc

Recruiting

Feasibility Study of Intra-Tumoral Lipopolysaccharide Immunotherapy for Intra-Abdominal (LPS)

Abdominal Cancer | Malignancy

United States
University of North Carolina, Chapel Hill
Environmental Protection Agency (EPA)

Completed

Systemic Inflammatory Response to CCRE (Endoscreen)

Healthy

United States
José Raimundo Araujo de Azevedo

Not yet recruiting

Resistance Profile of Escherichia Coli in Infections of Community Origin: The Importance of Antimicrobial Stewardship

Antimicrobial Resistance
Rutgers, The State University of New Jersey

Completed

Inflammation and the Host Response to Injury (In Healthy Volunteers) (Mono)

Immune System

United States
Jiangsu Province Centers for Disease Control and...
Chengdu Olymvax Biopharmaceuticals Inc.; PLA Army Medical University

Completed

A Clinical Trial to Evaluate a Recombinant Staphylococcus Aureus Vaccine (Escherichia Coli) in Healthy Adults

Staphylococcus Aureus Infection

China
National Institute of Environmental Health Sciences...
National Center for Research Resources (NCRR)

Completed

The Genetics of Environmental Asthma

Asthma

United States
Xiamen Innovax Biotech Co., Ltd
Xiamen University; Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.

Completed

A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)

Hepatitis E

China
Intercell USA, Inc.

Completed

ETEC Logistics Trial (TREK) (Trek)

Diarrhea

United States, Guatemala, Mexico
John Sundy
Sandler Program for Asthma Research

Terminated

Nitric Oxide, LPS and the Pathogenesis of Asthma Phase II

Healthy

United States
Aarhus University Hospital
University of Aarhus; Lundbeck Foundation

Completed

Endotoxin & Cytokines. Do Protein Loss and Metabolic Effects Depend on Central Nervous System (CNS) Activation of Stress Hormones or on Local Mechanisms in Muscle and Fat?

Glucose Metabolism Disorders | Inflammation

Denmark
NIZO Food Research

Completed

Characterization of Resistance Against Live-attenuated Diarrhoeagenic E. Coli (CORAL)

Gastroenteritis | Diarrhea | Bacterial Infections | Escherichia Coli Infections

Netherlands
Boehringer Ingelheim

Completed

Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of BI 653048 BS H3PO4 Capsule Assessing Endotoxin-induced Inflammatory Response in Healthy Male Subjects

Healthy
Washington University School of Medicine
Doris Duke Charitable Foundation

Completed

Assessing NOS Uptake With PET Imaging in Lung Inflammation

Lung Inflammation

United States
Xiamen Innovax Biotech Co., Ltd

Completed

A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Chronic Hepatitis B Patients )

Hepatitis E

China
Washington University School of Medicine
Barnes-Jewish Hospital

Completed

PET Imaging of Endotoxin-induced iNOS Activation

Pneumonia

United States
Erasmo Spaziani

Recruiting

Probiotic After Acute Colonic Diverticulitis

Therapy | Diverticulitis, Colonic

Italy
Adrenomed AG
Radboud University Medical Center

Completed

Adrecizumab-LPS Study

Healthy Volunteers

Netherlands
Janssen Research & Development, LLC

Completed

A Study Exploring the Use of Vaccine and Antigen Challenges for Immune Monitoring in Healthy Participants

Healthy

Belgium
Advagene Biopharma Co. Ltd.

Completed

A Phase 2, Double-blind Study to Evaluate Intranasal Trivalent Influenza Virus Vaccine in Healthy Adult

Influenza Infection

Taiwan
International Vaccine Institute
Indian Council of Medical Research; Institute of Child Health; National Institute... and other collaborators

Unknown

Safety and Immunogenicity of a Killed Oral Cholera Vaccine in Infants

Diarrhea | Cholera | Vibrio Infections

India
National Institute of Allergy and Infectious Diseases...

Completed

Phase 1 Study of dmLT ID Vaccination in Healthy Adults

Gastroenteritis Escherichia Coli

United States
International Vaccine Institute
Bill and Melinda Gates Foundation; Thrasher Research Fund; Open Philanthropy

Not yet recruiting

Safety and Immunogenicity of Hecolin® in Healthy Pregnant Women

Hepatitis E Infection

Pakistan
Xiamen Innovax Biotech Co., Ltd

Completed

A Study on the Recombinant Hepatitis E Vaccine (Escherichia Coli) (Accelerated Vaccination Schedule)

Hepatitis E

China

Search clinical trials for: Escherichia coli Endotoxin (LPS)

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