Search clinical trials for: FGFR Inhibitor

Total 64759 results

Omega Therapeutics

Recruiting

A Phase 1/2 Study to Evaluate OTX-2002 in Patients With Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association With the MYC Oncogene (MYCHELANGELO I)

Hepatocellular Carcinoma | Solid Tumor | Liver Cancer | Hepatocellular Carcinoma Non-resectable | Hepatocellular Cancer | Hepatocellular Carcinoma Recurrent | Liver, Cancer of, Non-Resectable

United States, Hong Kong, Korea, Republic of, Singapore, Taiwan
Eastern Cooperative Oncology Group
Janssen, LP

Recruiting

Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL

T-cell Acute Lymphoblastic Leukemia

United States
YM BioSciences

Completed

Phase 2 Study of Nimotuzumab in Pediatric Recurrent Diffuse Intrinsic Pontine Glioma

Recurrent Diffuse Pontine Gliomas

United States, Canada, Israel
University of Colorado, Denver

Completed

Effects of Ledipasvir/Sofosbuvir on the Pharmacokinetics and Renal Safety of Tenofovir Alafenamide (TAF)

Hepatitis C | HIV Coinfection

United States
Fudan University
Shanghai Jiao Tong University -Pulse Medical Imaging Technology Joint Lab

Recruiting

Diagnostic Accuracy of CCTA-derived Versus AngiogRaphy-dErived QuantitativE Flow Ratio (CAREER) Study (CAREER)

Coronary Artery Disease | Coronary Stenosis | Hemodynamics | Coronary Computed Tomography Angiography

China
Tianjin Chest Hospital

Recruiting

Intravascular Ultrasound-derived Assessment of Hemodynamically Negative Lesions in NSTEACS Patients (IMPACT-NSTEACS)

Non-ST-segment Acute Coronary Syndrome

China
Stanford University

Enrolling by invitation

Imaging of Osteonecrosis With Ferumoxytol-Enhanced MRI (Osteonecro)

Osteonecrosis

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC... and other conditions

United States
Kufa University

Completed

Combined Sertraline and Ketoprofen Administration in Major Depressive Disorder (Srt+ktpMDD)

Major Depressive Disorder
AstraZeneca

Completed

Quetiapine XR Versus Sertraline in Acute Bipolar Depression as add-on Therapy

Bipolar Disorder | Bipolar Depression

Spain
Shanghai Ninth People's Hospital Affiliated to...

Recruiting

Camrelizumab Combined With Apatinib Mesylate for Head and Neck Squamous Cell Carcinoma (IMplus)

Head and Neck Squamous Cell Carcinoma

China
The Catholic University of Korea

Completed

DPP4 Inhibitor and Coronary Atherosclerosis in Patients Receiving Insulin Therapy

Diabetes Mellitus

Korea, Republic of
Second Affiliated Hospital of Guangzhou Medical...
Guangdong Zhaotai InVivo Biomedicine Co. Ltd.; Hunan Zhaotai Yongren Medical...

Recruiting

GPC3/Mesothelin/Claudin18.2/GUCY2C/B7-H3/PSCA/PSMA/MUC1/TGFβ/HER2/Lewis-Y/AXL/EGFR-CAR-T Cells Against Cancers

Cancer | Lung Cancer | Immunotherapy | CAR-T Cell

China
Medical Practice Prof D. Ivanov

Completed

ARB, ACEi, DRi Effects on COVID-19 Course Disease (BIRCOV)

COVID-19 | Hypertension

Ukraine
Tesaro, Inc.

Completed

A Phase I/IIa Open-Label, Dose Escalation and Cohort Expansion Trial of Oral TSR-011 in Patients With Advanced Solid Tumors and Lymphomas

Solid Tumors | Lymphomas

United Kingdom, United States, Taiwan, Spain, Poland
Shanghai University of Traditional Chinese Medicine
Shanghai Chest Hospital

Unknown

Efficacy Study of Chinese Medicine Plus EGFR-TKI Versus EGFR-TKI in Advanced Pulmonary Adenocarcinoma

Cancer
Nahla H Tohami

Unknown

Effect of Sodium Glucose co Transporter 2 Inhibitor ( SGLT2) on Proteinuria in Diabetic Patients

Diabetic Nephropathies

Egypt
University of Florida
American Society of Nephrology

Withdrawn

Severe Sepsis in Children - IMPRESS-C (IMPRESS-C)

Hypertension | Chronic Kidney Disease | Acute Kidney Injury

United States
LMC Diabetes & Endocrinology Ltd.
Merck Sharp & Dohme LLC; Syreon Corporation

Withdrawn

Approaches To Therapy Escalation In T2D (ATTACC)

Type2 Diabetes
Sadat City University
Beni-Suef University

Completed

Which is Better to Start With DPP-4 Inhibitors or SGLT-2 Inhibitors in Egyptian Diabetic Patients?

Diabete Type 2

Egypt
GlaxoSmithKline

Completed

Study To Evaluate Long Term Maintenance With TRIZIVIR After Boosted Protease Inhibitor (PI) Or Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) In HIV-1 Infected Adults

HIV Infections
Panineeya Mahavidyalaya Institute of Dental Sciences...

Completed

The Association of SERPINA1 Gene Disturbance in Patients With Lung and Gum Disorders (SA1PLG)

Pulmonary Disease, Chronic Obstructive | Generalized Chronic Periodontitis

India
Pfizer

Completed

A Study Of Combined C- MET Inhibitor And PAN-HER Inhibitor (PF-02341066 And PF-00299804) In Patients With Non- Small Cell Lung Cancer

Non Small Cell Lung Cancer

United States, Australia
G1 Therapeutics, Inc.

Recruiting

Trilaciclib vs Placebo in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Receiving Topotecan

Extensive-stage Small-cell Lung Cancer

Spain, Greece, Turkey, Poland, Georgia, Austria, Belgium, Bulgaria, Germany, Hungary
Saint Petersburg State University, Russia

Recruiting

Efficacy and Safety of Focused Shockwave Therapy Plus Tadalafil vs Tadalafil Alone in Patient With Erectile Dysfunction

Erectile Dysfunction

Russian Federation
Shanghai Jiao Tong University School of Medicine

Recruiting

Neoadjuvant Personalized Anti-PD-1 and Anti-VEGFR Therapy in OSCC Patients

Oral Squamous Cell Carcinoma | Anti-PD-1 | Neoadjvant Therapy | Anti-VEGFR

China
Assiut University

Not yet recruiting

Irisin And Diabetic Nephropathy

Irisin
Dragonboat Biopharmaceutical Company Limited
Shanghai East Hospital

Unknown

A Preliminary Clinical Study on the Pharmacokinetics and Safety of CDP1 in Patients With Advanced CRC or HNSCC

Colorectal Cancer

China
University of Wisconsin, Madison

Completed

Effect of ACE-inhibitors on Aortic Stiffness in Elderly Patients With Chronic Kidney Disease

Cardiovascular Disease | Chronic Kidney Disease

United States
Leiden University Medical Center
Galapagos NV

Recruiting

JAK Inhibition in Ulcerative Colitis

Colitis, Ulcerative

Netherlands
Alimentiv Inc.
Alimentiv Translational Research Consortium

Terminated

Identification of Biomarkers of Janus Kinase Inhibitor Therapy in Patients With Ulcerative Colitis (PROPHETIC)

Ulcerative Colitis

Netherlands
Celgene

Completed

NPI-0052 and Vorinostat in Patients With Non-small Cell Lung Cancer, Pancreatic Cancer, Melanoma or Lymphoma

Melanoma | Lymphoma | Multiple Myeloma | Pancreatic Cancer | Non-Small Cell Lung Cancer

Australia
Anwaar Saeed
AstraZeneca; Exelixis

Active, not recruiting

Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies (CAMILLA)

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Adenocarcinoma

United States
Shanghai Henlius Biotech

Not yet recruiting

A Randomized, Single Intravenous Dose, Parallel Phase I Clinical Study to Compare the Pharmacokinetic Characteristics, Safety, and Immunogenicity of HLX05 Vs. Erbitux® (Cetuximab) in Healthy Adult Male Chinese Subjects

EGFR Overexpression
Eli Lilly and Company

Completed

A Study of LY3015014 in Healthy Participants With Elevated Low Density Lipoprotein Cholesterol

Hyperlipidemia

United States
National Cancer Institute (NCI)
GlaxoSmithKline

Completed

Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Metastatic Triple-Negative Breast Cancer

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Invasive Breast Carcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma

United States
Mario Negri Institute for Pharmacological Research
Agenzia Italiana del Farmaco

Completed

Angiotensin-converting-enzyme (ACE) Inhibitors in Hemodialysis (ARCADIA)

Hypertension | Left Ventricular Hypertrophy

Italy
Fourth Affiliated Hospital of Guangxi Medical University
Guilin Medical University, China; Wuzhou Red Cross Hospital; Second Affiliated... and other collaborators

Recruiting

Concurrent and Adjuvant Nimotuzumab Combined With Induction Chemotherapy Plus Chemoradiation in Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma by AJCC V8 Stage

China
Gilead Sciences

Completed

Study of Magrolimab Combinations in Participants With Myeloid Malignancies

Myeloid Malignancies

United States, Australia, United Kingdom
University of Florence
Azienda Ospedaliero-Universitaria Careggi; Istituto per lo Studio, la Prevenzione...

Recruiting

SLPI for Prostate Cancer

Prostate Cancer | Prostatic Neoplasm

Italy
University of Bologna

Completed

CoQ10 in Statin-associated Asthenia

Hypercholesterolemia | Physical Performance

Italy
Lisa Barrett
Nova Scotia Health Authority; Dalhousie University

Active, not recruiting

Treatment of Moderate to Severe Coronavirus Disease (COVID-19) in Hospitalized Patients

COVID-19

Canada
University of Massachusetts, Worcester

Completed

A Trial of Chemo & Radiation Therapy for Pancreatic Cancer

Pancreatic Cancer
National Cancer Institute (NCI)

Completed

Dinaciclib in Treating Patients With Relapsed or Refractory Multiple Myeloma

Refractory Multiple Myeloma

United States, Singapore
Pfizer

Completed

Comparative Real World Tumor Response in Pre-menopausal Metastatic Breast Cancer Patients Treated With Palbociclib + Aromatase Inhibitor or Aromatase Inhibitor Alone

Metastatic Breast Cancer

United States
Universitätsklinikum Hamburg-Eppendorf
German Federal Ministry of Education and Research; University Hospital Heidelberg

Recruiting

Stop of Proton-pump Inhibitor Treatment in Patients With Liver Cirrhosis - a Double-blind, Placebo-controlled Trial (STOPPIT)

Liver Cirrhosis

Germany
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Daratumumab in Treating Transplant-Eligible Patients With Multiple Myeloma

Plasma Cell Myeloma

United States
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Hypercholesterolemia
Grifols Therapeutics LLC

Terminated

Study to Evaluate the Safety and Efficacy of Liquid Alpha1-Proteinase Inhibitor (Human) in Hospitalized Participants With Coronavirus Disease (COVID-19)

COVID-19

United States, Brazil, Chile, Colombia, Mexico
Azienda Ospedaliera Universitaria Policlinico "G...
Gianluca Di Bella; Antonio Micari; Giampiero Vizzari; Giorgio Quadri; Greca Zanda; Ferdinando...

Recruiting

De-escalating Antiplatelet Therapy to Assess Platelet Reactivity and Outcomes in High Bleeding Risk Patients With Recent ACS (DESC-HBR)

Coronary Artery Disease | Acute Coronary Syndrome | Dual Antiplatelet Therapy

Italy

Search clinical trials for: FGFR Inhibitor

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