Search clinical trials for: Fibrinolytic Agents

Total 188884 results

Centre Hospitalier Universitaire de Nice

Completed

Clinical Efficacy of In-situ Thrombolysis in Case of Intraventricular Haemorraghia by Aneurysm Rupture

Subarachnoid Hemorrhage | Aneurysm, Ruptured

France
Brigham and Women's Hospital
Boston Scientific Corporation

Not yet recruiting

Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE (SONIC-PE)

Pulmonary Embolism | Right Ventricular Dysfunction | Right Ventricular Failure
Bausch & Lomb Incorporated

Terminated

Study to Evaluate Plasmin for the Creation of a Posterior Vitreous Detachment

Vitreoretinal Traction Syndrome

United States
University of Zurich
University Hospital, Geneva; Centre Hospitalier Universitaire Vaudois; University... and other collaborators

Not yet recruiting

SWIFT - SWIss Factor XIII Trial in PPH (SWIFT)

Hemorrhage | Coagulation Disorder | Postpartum Hemorrhage | Postpartum Complication | Coagulation Factor Deficiency

Switzerland
Bausch & Lomb Incorporated

Terminated

A Study to Evaluate Plasmin for the Creation of a Posterior Vitreous Detachment (PVD)

Vitreoretinal Traction Syndrome

United States
ThromboGenics

Terminated

Intra-arterial Microplasmin Administration in Patients With Acute Peripheral Arterial Occlusion

Arterial Occlusive Diseases

Belgium
ThromboGenics

Completed

Intravenous Administration of Microplasmin for Treatment of Acute Ischemic Stroke

Stroke, Acute

Germany, Belgium, Austria
ThromboGenics

Completed

The Purpose of This Study is to Evaluate the Pharmacokinetic Properties of Intravitreal Ocriplasmin Prior to Planned Primary Pars Plana Vitrectomy (PPV) (MIVI-10)

Vitrectomy

Belgium
Children's Hospital of Orange County
CSL Behring

Completed

Clinical Trial of Factor XIII (FXIII) Concentrate

Hemophilia | Factor XIII Deficiency

United States
Dr. Wiley Chung

Recruiting

VATS Decortication Versus IR Guided Chest Tube Insertion With Fibrinolytics for the Management of Empyema (DICE)

Empyema, Pleural

Canada
ThromboGenics

Terminated

A Study to Evaluate the Efficacy and Safety of Ocriplasmin in Inducing Total PVD in Subjects With NPDR (CIRCLE)

Disease Progression | Diabetic Retinopathy | Posterior Vitreous Detachment

United States, Czechia, United Kingdom, France, Germany, Hungary, Spain, Israel, Italy
Children's Mercy Hospital Kansas City

Completed

Thoracoscopy Versus Fibrinolysis in Children With Empyema

Empyema

United States
CSL Behring

Completed

A Study of the Use of Factor XIII Concentrate in Patients With Inherited FXIII Deficiency

Factor XIII Deficiency

United States, Spain
Grifols Therapeutics LLC

Completed

A Safety and Dose Finding Study of Plasmin (Human) Administered Into the Middle Cerebral Artery of Stroke Patients

Acute Ischemic Stroke

Spain, Australia, France, Austria, Serbia, Slovakia
Lee's Pharmaceutical Limited

Unknown

A Clinical Study of Anfibatide in Acquired Thrombotic Thrombocytopenic Purpura (TTP)

Acquired Thrombotic Thrombocytopenic Purpura

China
NYU Langone Health
Eli Lilly and Company; The Cleveland Clinic; Centocor, Inc.

Completed

Female Sex is an Independent Predictor of Death and Bleeding Among Fibrinolytic Treated Patients With AMI

Myocardial Infarction

United States
University Hospital, Caen

Suspended

Intraventricular Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage. (FIVHeMA)

Subarachnoid Hemorrhage

France
ThromboGenics

Completed

A Study to Compare Multiple Doses Intravitreal Microplasmin for Treatment of Patients With Vitreomacular Traction (MIVI-IIt)

Vitreomacular Traction

Belgium, Germany
Beth Israel Deaconess Medical Center

Completed

Fibrinolysis Compared to Thoracoscopy for Pleural Infection

Pleural Diseases | Pleural Infection

United States
CSL Behring

Completed

A Study of Factor XIII Concentrate in Subjects With Congenital Factor XIII Deficiency

Factor XIII Deficiency

United States, Spain
ThromboGenics

Completed

A Study of the Safety and Efficacy of Microplasmin to Induce a Posterior Vitreous Detachment (MIVI III)

Vitrectomy

United States
Denver Health and Hospital Authority

Completed

Treatment of Complicated Parapneumonic Effusion With Fibrinolytic Therapy Versus VATs Decortication

Coagulopathy | Empyema, Pleural | Parapneumonic Effusion

United States
CCRF Inc., Beijing, China
Abbott Medical Devices

Not yet recruiting

A Prospective Evaluation of Clinical Impact of Physiology Versus Optical Coherence Tomography Guided PCI in STEMI Patients Without Undergoing Primary PCI

ST Elevation Myocardial Infarction
All India Institute of Medical Sciences, New Delhi

Completed

A Study Comparing a New Dosing Regimen of Clot-dissolving Drug for Mechanical Heart Valves Which Show Clots (RAFT-PVT)

Prosthetic Valve Thrombosis
Bin He

Recruiting

Changes of Cardiopulmonary Function After Thrombolysis in Patients With Pulmonary Embolism (CCFATAPE)

Acute Pulmonary Embolism

China
Yonsei University

Recruiting

Prognostic Value of Soluble Urokinase-type Plasminogen Activator Receptor in Valvular Heart Disease

Severe Aortic Stenosis or Severe Aortic Regurgitation

Korea, Republic of
Sorlandet Hospital HF

Completed

Predictors of Outcome in t-PA Treated Stroke.

Ischemic Stroke

Norway
Zagazig University

Completed

Troponin- I Elevation Predicts Outcome After Thrombolysis in Stroke Patients

Cerebrovascular Accident
Marmara University

Completed

suPAR in the Early Diagnosis of Acute Kidney Injury(AKI) After On-Pump Cardiac Surgery

Acute Kidney Injury

Turkey
Odense University Hospital
Aarhus University Hospital

Completed

Urine-plasminogen as a Predictor for Development Of Preeclampsia in Pregnant Women With Type 1 Diabetes Mellitus

Type 1 Diabetes | Preeclampsia

Denmark
Georgetown University
Johns Hopkins University; University of Alabama at Birmingham; University of... and other collaborators

Completed

Acute Stroke Program of Interventions Addressing Racial and Ethnic Disparities (ASPIRE)

Stroke

United States
Federal University of São Paulo

Completed

Hospital Mortality in Patients Submitted to Pharmacoinvasive Strategy With Tenecteplase (TNK)

Acute Coronary Syndrome

Brazil
University of Oklahoma

Completed

Urokinase Like Plasminogen Activator Levels in Patients Undergoing Bronchoscopy

Hemoptysis

United States
Temple University

Completed

The Effect of Implementing Hyper-acute Stroke Guidelines on Decision-Making for or Against Thrombolytic Therapy for Stroke in the Emergency Department

Stroke

United States
Far Eastern Memorial Hospital
Fu Jen Catholic University

Completed

A Qualitative Study of Delays in Hospital Admission in Patient With Acute Stroke

Acute Ischemic Stroke
Chinese University of Hong Kong

Recruiting

Ex Vivo Test of New Stroke Treatment Using Magnetic Nanorobots

Thrombosis

Hong Kong
Assiut University

Not yet recruiting

Plasma Soluble Urokinase Plasminogen Activator Receptor and Behçet's Disease .

Behçet Disease
St. Marianna University Toyoko Hospital

Enrolling by invitation

Kanagawa Intravenous and Endvascular Treatment Registry (K-NET)

Acute Ischemic Stroke

Japan
St. Olavs Hospital
Norwegian University of Science and Technology

Completed

Traumatic Intracranial Hemorrhage in Users of Oral Antithrombotic Drugs

Embolism and Thrombosis | Intracranial Hemorrhage, Traumatic | Hematoma, Subdural, Intracranial
Genentech, Inc.

Completed

An Observational Study of TNKase in Patients Enrolled in the National Registry of Myocardial Infarction 4 and 5 (POST)

Acute Myocardial Infarction
University Hospital, Lille

Completed

Pre-stroke Cognitive Status and Thrombolytic Therapy (OPHELIE-COG)

Brain Ischemia | Dementia | Adverse Effect of Thrombolytic Drugs | Impaired Cognition

France, Japan
University of California, San Diego
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Stroke Team Remote Evaluation Using a Digital Observation Camera (STRokE DOC)

Stroke

United States
Mayo Clinic

Completed

Early Mobilization of Ischemic Stroke Patients Within 24-hours After Intravenous-Tissue Plasminogen Activator (IV-tPA) (EMISTPA)

Ischemic Stroke

United States
CSL Behring

Completed

An Open Enrollment Study of Factor XIII Concentrate in Subjects With Congenital Factor XIII Deficiency

Factor XIII Deficiency

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Tenecteplase Treatment in Ischemic Stroke Registry (TETRIS)

Stroke, Acute

France
Xijing Hospital

Completed

Correlation Study of PAI-1 4G/5G Polymorphism and Postoperative AKI in Patients With Aortic Dissection

Aortic Dissection | AKI - Acute Kidney Injury | PAI-1 4G/5G Polymorphism

China
Karolinska Institutet

Completed

Prehospital Recognition and Identification of Unspecific Symptoms (PRIUS)

Morality | Serious Condition

Finland, Sweden
St. Joseph's Hospital and Medical Center, Phoenix
National Institutes of Health (NIH); Translational Genomics Research Institute

Completed

Identification of Novel Molecular Markers for Cerebral Ischemia From Patients With Minor and Devastating Ischemic Injury

Cerebral Ischemia

United States
Fondation Ophtalmologique Adolphe de Rothschild

Withdrawn

Impact of Neutrophil Extracellular Traps on Tissue Plasminogen Activator Induced Thrombolysis in Acute Ischemic Stroke Patients (THROMBONETS)

Acute Stroke

France
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Genetic Architecture of Plasma T-PA and PAI-1

Heart Diseases | Cardiovascular Diseases | Thrombosis | Atherosclerosis

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