Search clinical trials for: GABA Agents

Total 187736 results

Transcept Pharmaceuticals

Completed

A Study of Zolpidem Tartrate Sublingual Tablet in Adult Patients With Insomnia

Insomnia
Children's Mercy Hospital Kansas City
Gabi SmartCare

Enrolling by invitation

WIReD: Wireless Interstage Remote Device Study (WIReD)

Pediatrics | Congenital Heart Disease in Children | Vital Signs | Remote Monitoring

United States
Currax Pharmaceuticals
Henry Ford Hospital

Completed

Assess the Effect of Zolpidem, Silenor & Placebo on Arousability, Ataxia/Balance & Cognition in Healthy Volunteers

Healthy

United States
Chinese University of Hong Kong

Terminated

Effect of GABAB Agonist on Visceral Hyperalgesia in NCCP patientsChinese?

Non-Cardiac Chest Pain

China
Marinus Pharmaceuticals

Completed

Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder (Marigold)

CDKL5 Deficiency Disorder

United States, Australia, France, Israel, Italy, Poland, Russian Federation, United Kingdom
Northwell Health
National Institute of Mental Health (NIMH)

Completed

Electroconvulsive Therapy in Clozapine Refractory Schizophrenia

Schizophrenia

United States
UCB Biopharma SRL

Completed

A Study to Assess the Pulmonary Safety of Staccato Alprazolam in Healthy Study Participants and in Study Participants With Mild Asthma

Healthy Study Participants | Participants With Mild Asthma

United States
UCB Biopharma SRL

Completed

Study to Assess the Safety, Tolerability, And Pharmacokinetics of Staccato Alprazolam in Healthy Japanese, Chinese, and Caucasian Participants

Healthy Study Participants

United States
Alexza Pharmaceuticals, Inc.

Completed

Staccato Alprazolam Single Dose PK

Healthy
Duke University

Completed

Efficacy and Safety of Temazepam in HIV Seropositive Patients With Insomnia

Insomnia
H. Lundbeck A/S

Withdrawn

An Investigational Drug Study in Healthy Adult Volunteers in a Model of Insomnia (0928-007)

Insomnia
Vanderbilt University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Hypoglycemia Associated Autonomic Failure in Type 1 DM, Q2

Type 1 Diabetes

United States
Yao Yusheng
West China Hospital

Completed

Effects of Dexmedetomidine Premedication on Emergence Agitation After Strabismus Surgery in Children

Delirium on Emergence | Inhalational Anesthetics Adverse Reaction | Strabismus Following Ocular Surgery

China
National Institute on Drug Abuse (NIDA)
University of Cincinnati

Completed

Tiagabine for the Treatment of Cocaine Dependence - 1

Cocaine-Related Disorders

United States
Neurocrine Biosciences

Withdrawn

An Exploratory Study of NBI-34060 Capsules and Next Day Functioning

Insomnia

United States
Indivior Inc.

Completed

A Phase 1 Bioavailability Study of Arbaclofen Placarbil Modified Release Formulations in Healthy Volunteers

Healthy Volunteers

United Kingdom
Tanta University

Recruiting

Baclofen Versus Gabapentin in Preventing Postoperative Pain After Laparoscopic Sleeve Gastrectomy

Post Operative Pain

Egypt
National Institute on Alcohol Abuse and Alcoholism...
Astellas Pharma Inc

Completed

Human Laboratory Study of ASP8062 for Alcohol Use Disorder

Alcohol Drinking | Alcohol Use Disorder | Alcohol Use Disorder (AUD)

United States
University of British Columbia

Withdrawn

Study of the Effect of Dosing on Clozapine Levels (PK-CLZ)

Psychotic Disorders | Schizophrenia

Canada
Prof. Daniele Zullino

Completed

Nalmefene, Baclofen and Impulsivity in Subjects With Alcohol Use Disorder and Healthy Control Subjects

Alcohol Use Disorder

Switzerland
UCB Biopharma SRL

Completed

A Study to Assess the Pharmacokinetics (PK) and Safety of Staccato Alprazolam in Adolescent Study Participants With Epilepsy

Epilepsy

United States
Ovid Therapeutics Inc.

Completed

A Study in Adults and Adolescents With Angelman Syndrome (STARS)

Angelman Syndrome

United States, Israel
Pfizer's Upjohn has merged with Mylan to form Viatris...
Investigacion Farmacologica y Biofarmaceutica, S.A. de C.V.

Withdrawn

A Study Of Two Oral Preparations Of 2 Mg Alprazolam In Healthy Volunteers Under Fasting Conditions

Healthy
Orion Corporation, Orion Pharma

Completed

Bioequivalence Study Comparing Two Alprazolam 1 mg Tablets Under Fed Conditions

Healthy

Finland
Hadine Joffe, MD
National Institute of Mental Health (NIMH)

Completed

Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia

Depression | Sleep Initiation and Maintenance Disorders

United States
Saladax Biomedical, Inc.
University of Maryland, Baltimore; The Feinstein Institutes for Medical Research

Completed

Clozapine Therapy Sample Collection - Method Comparison Study

Patients Prescribed Clozapine

United States
Dartmouth-Hitchcock Medical Center
National Institute on Drug Abuse (NIDA); University of South Carolina; University... and other collaborators

Completed

Treatment of Schizophrenia and Comorbid Cannabis Use Disorder: Comparing Clozapine to Treatment-as-Usual

Schizophrenia | Schizoaffective Disorder | Dual Diagnosis | Cannabis Abuse | Psychotic Disorder

United States
Manhattan Psychiatric Center
Azur Pharma, Inc

Completed

Equivalence of Generic Clozapine to Orally Dissolving Clozapine in Schizophrenia or Schizoaffective Disorder

Schizophrenia | Schizoaffective Disorder

United States
University Medical Centre Ljubljana

Completed

Pathophysiology of Tremor-modulating Mechanisms of Propranolol and Primidone in Essential Tremor

Essential Tremor

Slovenia
Aristotle University Of Thessaloniki
Greek Alzheimer's Association and Related Disorders

Recruiting

The Effects of Cannabidiol and Homotaurine in Patients With Mild Cognitive Impairment

Mild Cognitive Impairment

Greece
Shanghai Jiao Tong University School of Medicine

Not yet recruiting

Improvement Effects of Gamma Aminobutyric Acid（GABA） Supplementation on Treatment of Children With Insomnia

Insomnia
Pfizer
Medivation, Inc.

Completed

A Study To Evaluate The Abuse Potential Of Single Oral Doses Of Dimebon (Latrepirdine) In Healthy Recreational Polydrug Users

Alzheimer's Disease | Huntington's Disease
Shanghai Mental Health Center

Completed

The Efficacy of Computerized Cognitive Remediation Therapy for Chronic Schizophrenia

Schizophrenia

China
Imperial College London

Recruiting

Evaluating the Safety of Acute Baclofen in Methadone-maintained Individuals With Opiate Dependence. (FORWARDS-1)

Addiction Opiate

United Kingdom
Ministry of Health, Israel

Unknown

Double Blind Placebo Control Opipramol-Baclofen Treatment for Addiction

Drug Abuse

Israel
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42847922 in Participants With Insomnia Disorder

Insomnia Disorders

Belgium, United States, Germany, Poland, Japan, France
Transcept Pharmaceuticals

Completed

Driving Performance After Middle of the Night Administration of 3.5 mg Zolpidem Tartrate Sublingual Tablet

Insomnia

Netherlands
XenoPort, Inc.

Completed

Efficacy and Safety of Arbaclofen Placarbil in Subjects With Spasticity Due to Multiple Sclerosis

Multiple Sclerosis

United States
Tanta University

Unknown

Baclofen in the Treatment of Muscle Cramps in Patients With Cirrhosis

Liver Cirrhosis | Muscle Cramps

Egypt
UCB Biopharma SRL

Enrolling by invitation

A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

Stereotypical Prolonged Seizures

United States, Bulgaria, China, Czechia, Germany, Hungary, Italy, Japan, Poland, Spain, United Kingdom, Australia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Pharmacokinetics Of Alprazolam Sublingual Tablet Versus Conventional Tablet

Anxiety Disorder

United States
UCB Pharma

Completed

A Multicenter, Open-Label, Randomized Crossover Trial to Assess Subject Preference for Alprazolam Orally Disintegrating Tablets Compared to Conventional Alprazolam Tablets in Subjects With Anxiety

ANXIETY

United States
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Clorazepate Dipotassium 15mg Tablets Under Fasting Conditions

Healthy

United States
Brown University

Completed

A Study on the Biobehavioral Mechanisms of Baclofen and Alcohol Drinking

Alcoholism

United States
Brigham and Women's Hospital

Completed

Tiagabine to Enhance Slow Wave Sleep in Patients With Sleep Apnea (TESSA)

Sleep Apnea, Obstructive

United States
Centre for Addiction and Mental Health
The Ian Douglas Bebensee Foundation

Completed

Switching Antipsychotics: Abrupt Discontinuation Versus Overlap

Schizophrenia | Schizoaffective Disorder

Canada
National Institute of Mental Health (NIMH)

Completed

Clozapine for Treatment-Resistant Mania

Bipolar Disorder

United States
Wageningen University
Nunhems; Agrico Research; Avebe

Completed

Relative Oral Bioavailability of GABA From Tomatoes

GABA Plasmakinetics

Netherlands
Marinus Pharmaceuticals

Not yet recruiting

Double-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years Old

CDKL5 Deficiency Disorder
UCB Pharma

Completed

Trial to Compare Time to Response in the Symptoms of Anxiety to Concomitant Treatment With Niravam™ and an SSRI or SNRI to Treatment With an SSRI or SNRI Alone in Subjects With Generalized Anxiety Disorder or Panic Disorder

Generalized Anxiety Disorder | Panic Disorder

United States

Search clinical trials for: GABA Agents

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