Search clinical trials for: GLP-1 receptor antagonist

Total 11584 results

Hvidovre University Hospital

Completed

Incretin Hormone Antagonism After Bariatric Surgery (INCA-BAR)

Bariatric Surgery

Denmark
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Completed

Delinieation of GIP's Effects During a Meal in Humans Using GIP Receptor Antagonisation (GA-4)

Glucose Metabolism Disorders

Denmark
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Completed

Inhibition of the Endogenous GIP Response With a GIP Receptor Antagonist (GA-3)

Glucose Metabolism Disorders

Denmark
University of Copenhagen
Gentofte Hospital, Denmark

Recruiting

The Effect of GIP, GLP-1 and GLP-2 in Individuals With Genetically Altered Receptor Function (H-21044858)

Incretin Effect

Denmark
Mikkel Christensen
University of Copenhagen

Completed

GIP and GLP-1 in Type 1 Diabetes

Hypoglycemia

Denmark
University Hospital, Gentofte, Copenhagen

Completed

GIP/GLP-1 Co-Activity in Subjects With Obesity: Lowering of Food Intake (GASOLIN)

Obesity | Type 2 Diabetes | Adiposity

Denmark
University of Chicago

Completed

Incretin Regulation of Insulin Secretion in Monogenic Diabetes

Monogenic Diabetes

United States
University of Copenhagen
Hvidovre University Hospital

Completed

Gut Hormones and Bone Remodeling in Humans (KS-2) (KS-2)

Healthy

Denmark
Rigshospitalet, Denmark

Completed

Hyperglycemia and the Extra-pancreatic Effect of Incretins

Extra-pancreatic Incretin Effect | Glucose Effectiveness

Denmark
Zealand Pharma

Completed

A Single Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Healthy

Germany
University of Copenhagen
Hvidovre University Hospital

Recruiting

Gut Peptides and Bone Remodeling in Individuals With Spinal Cord Injury

Spinal Cord Injuries

Denmark
University of Mississippi Medical Center

Recruiting

Effect of GLP-1 Receptor Agonists on Trabecular Bone Score

Diabetes Mellitus, Type 2 | Osteoporosis, Postmenopausal

United States
University of Missouri-Columbia
American Society for Metabolic and Bariatric Surgery

Recruiting

Impact GLP-1 Agonists Following Bariatric

Hypertension | Diabetes Mellitus | Metabolic Syndrome | Morbid Obesity | Obstructive Sleep Apnea of Adult

United States
Herlev Hospital
University of Copenhagen; The Danish Medical Research Council; The Danish Diabetes...

Completed

GIP, GLP-1 and GLP-2 in Type 2 Diabetic Hyperglucagonemia

Type 2 Diabetes Mellitus

Denmark
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Effect of Gene Polymorphisms on GLP-1 Receptor Agonists Response in Patients With T2DM

Type 2 Diabetes Mellitus

China
Dasman Diabetes Institute

Recruiting

Relationship Between Improvement in Insulin Secretion and Decrease in HbA1c in GLP-1 RA Therapy in T2DM Patients

Diabetes Mellitus, Type 2

Kuwait
David D'Alessio, M.D.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Incretin Action in Physiology and Diabetes

Insulin Secretion

United States
Christina Kruuse

Recruiting

The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Stroke (EGRABIS1)

Ischemic Stroke

Denmark
University of Pennsylvania
Children's Hospital of Philadelphia

Recruiting

Beta-cell Response to Incretin Hormones in Cystic Fibrosis

Cystic Fibrosis | Pancreatic Insufficiency

United States
Ludwig-Maximilians - University of Munich
German Research Foundation; Merck Sharp & Dohme LLC

Completed

Exendin(9-39)Amide as a Glucagon-like Peptide-1 (GLP-1) Receptor Antagonist in Humans

Hyperglycemia

Germany
King's College London

Recruiting

Glucagon-like Peptide 1 (GLP1) Receptor Agonists and Mental Health

Obesity | Diabetes Mellitus | Mental Health Issue

United Kingdom
Azienda Ospedaliero-Universitaria Consorziale Policlinico...

Completed

Efficacy of Glucagon-like Peptide-1 Receptor Agonists According to Type 2 Diabetes Subtypes

Diabetes Mellitus, Type 2

Italy
Diabeteszentrum Bad Lauterberg im Harz

Completed

GLP-1 Mediating DPP-4 Inhibition in Type 2 Diabetes

Type 2 Diabetes

Germany
University of Copenhagen
Hvidovre University Hospital

Completed

Effects of Gut Peptides on Bone Remodeling (KS-3)

Healthy

Denmark
Christina Kruuse

Completed

The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Non-stroke Volunteers (EGRABINS1)

Stroke

Denmark
Radboud University Medical Center
Rijnstate Hospital

Recruiting

Visualizing Beta Cells After Bariatric Surgery (GLP1-bar)

Type 2 Diabetes Mellitus

Netherlands
University Hospital, Gentofte, Copenhagen

Completed

Effect of GIP After a Meal in Patients With Type 2 Diabetes (GA-7)

Type2 Diabetes

Denmark
Jose Seijas Amigo

Completed

SEMAGLUTIDE VERSUS GLP-1 RECEPTOR AGONISTS. EFFECTIVENESS , SAFETY AND QUALITY OF LIFE IN PATIENTS WITH DIABETES MELLITUS 2. OBSERVATIONAL, PROSPECTIVE AND MULTICENTER STUDY. SEVERAL STUDY. (SEVERAL)

Quality of Life | Diabetes Mellitus, Type 2 | Weight Loss | Safety Issues

Spain
Indiana University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Modulation of Human Myocardial Metabolism by GLP-1 Dose Response

Healthy | Type 2 Diabetes Mellitus

United States
Turku University Hospital
Lund University

Completed

Splanchnic Blood Redistribution After Incretin Hormone Infusion and Obesity Surgery (GIP-PET)

Obesity | Type 2 Diabetes

Finland
University of Copenhagen
Hvidovre University Hospital

Completed

Investigation of GLP-2 Mechanism of Action (GA-8)

Healthy

Denmark
Zealand Pharma
Profil Institut für Stoffwechselforschung GmbH

Recruiting

A Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Safety and Tolerability

Germany
Hvidovre University Hospital
University of Copenhagen

Completed

Effect of RYGB on Alpha- and Beta Cell Function and Sensitivity to Incretins in Patients With Type 2 Diabetes (BETASIN)

Obesity, Morbid | Type2 Diabetes

Denmark
Papworth Hospital NHS Foundation Trust

Unknown

GLP-1 Loading During Elective Percutaneous Coronary Intervention (GOLD-PCI)

Myocardial Infarction | Angina Pectoris | Coronary Heart Disease | Reperfusion Injury

United Kingdom
Johns Hopkins University

Terminated

Effect of GLP - 1 (7-36 Amide) on Myocardial Function Following Coronary Artery Bypass (CABG) Surgery (GLP-1 CABG)

CABG

United States
Uppsala University
Karolinska Institutet; University of Copenhagen

Completed

GIP and GLP-1 on Gastric Emptying, Appetite and Insulin-glucose (GIP-GLP-gas)

Physiology | Gastroenterology | Endocrinology

Sweden
University of Copenhagen
Copenhagen University Hospital, Hvidovre

Recruiting

Co-infusion of Neurotensin and GLP-1 Effects on Appetite and Food Intake.

Obesity

Denmark
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

Treating PCOS With Semaglutide vs Active Lifestyle Intervention (TEAL)

PCOS | NAFLD | Adolescent Obesity

United States
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Association of Gene Polymorphism With Susceptibility to T2DM and the Therapeutic Responses to Exenatide in Chinese Patients With T2DM

Type 2 Diabetes Mellitus | Susceptibility, Genetic

China
University Hospital Tuebingen
Merck Sharp & Dohme LLC

Withdrawn

Characterization of Beta Cell Failure

Diabetes | Metabolic Syndrome

Germany
University Hospital, Gentofte, Copenhagen
University of Copenhagen; Steno Diabetes Center Copenhagen

Completed

The Effect of GIP(3-30)NH2 (GA-10)

Endocrine - Other

Denmark
Rigshospitalet, Denmark
Department of Cardiovascular and Renal Research, University of Southern Denmark

Completed

Acute Effects of GLP-1 on Renal Hemodynamics (GLP1RRBF)

The GLP-1-mediated Gut-kidney Axis

Denmark
PegBio Co., Ltd.

Completed

Safety and Efficacy of Pegylated Exenatine Injection (PB-119) in Drug-naïve T2DM Subjects (PB119)

Type 2 Diabetes Mellitus (T2DM)

China
PegBio Co., Ltd.

Completed

Safety and Efficacy of PB-119 in Subjects With Type 2 Diabetes and Not Well-controlled by Metformin Monotherapy

Type 2 Diabetes Mellitus (T2DM)

China
University of Padova
Azienda Ospedaliera di Padova

Unknown

GLP-1 REceptor Agonists and Real World EvIdeNce (GLP-1REWIN)

Type 2 Diabetes

Italy
Mayo Clinic
Merck Sharp & Dohme LLC

Completed

GLP1R Polymorphisms and Response to GLP1

Diabetes

United States
University Hospital, Gentofte, Copenhagen

Completed

Oxyntomodulin, Mechanisms of Action in Relation to Appetite, Food Intake, Gastric Emptying and Energy Expenditure.

Obesity | Incretin Action

Denmark
University of Maryland, Baltimore

Active, not recruiting

GLP-1 and Hypoglycemia

Type 2 Diabetes Mellitus

United States
Amsterdam UMC, location VUmc

Completed

Effects of Glucagon Like Peptide-1(GLP-1) and Liraglutide on Brain Satiety and Reward Circuits and Feeding Behavior in Diabetes (LIBRA)

Obesity | Type 2 Diabetes

Netherlands
Institut de Recherches Internationales Servier

Active, not recruiting

Study of AG-120 and AG-881 in Subjects With Low Grade Glioma

Glioma

United States

Search clinical trials for: GLP-1 receptor antagonist

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