Search clinical trials for: GLP-1 agonists

Total 27174 results

University of Copenhagen
Gentofte Hospital, Denmark

Recruiting

The Effect of GIP, GLP-1 and GLP-2 in Individuals With Genetically Altered Receptor Function (H-21044858)

Incretin Effect

Denmark
Mikkel Christensen
University of Copenhagen

Completed

GIP and GLP-1 in Type 1 Diabetes

Hypoglycemia

Denmark
Zealand Pharma
Profil Institut für Stoffwechselforschung GmbH

Recruiting

A Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Safety and Tolerability

Germany
Rigshospitalet, Denmark

Completed

Hyperglycemia and the Extra-pancreatic Effect of Incretins

Extra-pancreatic Incretin Effect | Glucose Effectiveness

Denmark
Zealand Pharma

Completed

A Single Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Healthy

Germany
University of Missouri-Columbia
American Society for Metabolic and Bariatric Surgery

Recruiting

Impact GLP-1 Agonists Following Bariatric

Hypertension | Diabetes Mellitus | Metabolic Syndrome | Morbid Obesity | Obstructive Sleep Apnea of Adult

United States
Hvidovre University Hospital

Completed

Incretin Hormone Antagonism After Bariatric Surgery (INCA-BAR)

Bariatric Surgery

Denmark
University of Mississippi Medical Center

Recruiting

Effect of GLP-1 Receptor Agonists on Trabecular Bone Score

Diabetes Mellitus, Type 2 | Osteoporosis, Postmenopausal

United States
University Hospital, Gentofte, Copenhagen

Completed

GIP/GLP-1 Co-Activity in Subjects With Obesity: Lowering of Food Intake (GASOLIN)

Obesity | Type 2 Diabetes | Adiposity

Denmark
David D'Alessio, M.D.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Incretin Action in Physiology and Diabetes

Insulin Secretion

United States
University of Copenhagen
Hvidovre University Hospital

Completed

Gut Hormones and Bone Remodeling in Humans (KS-2) (KS-2)

Healthy

Denmark
Dasman Diabetes Institute

Recruiting

Relationship Between Improvement in Insulin Secretion and Decrease in HbA1c in GLP-1 RA Therapy in T2DM Patients

Diabetes Mellitus, Type 2

Kuwait
University of Pennsylvania
Children's Hospital of Philadelphia

Recruiting

Beta-cell Response to Incretin Hormones in Cystic Fibrosis

Cystic Fibrosis | Pancreatic Insufficiency

United States
University of Copenhagen
Hvidovre University Hospital

Recruiting

Gut Peptides and Bone Remodeling in Individuals With Spinal Cord Injury

Spinal Cord Injuries

Denmark
Herlev Hospital
University of Copenhagen; The Danish Medical Research Council; The Danish Diabetes...

Completed

GIP, GLP-1 and GLP-2 in Type 2 Diabetic Hyperglucagonemia

Type 2 Diabetes Mellitus

Denmark
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Completed

Delinieation of GIP's Effects During a Meal in Humans Using GIP Receptor Antagonisation (GA-4)

Glucose Metabolism Disorders

Denmark
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Completed

Inhibition of the Endogenous GIP Response With a GIP Receptor Antagonist (GA-3)

Glucose Metabolism Disorders

Denmark
Zydus Lifesciences Limited

Completed

A Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ZYD1, Following Subcutaneous Administration in Healthy Volunteers (ZYD1)

Type 2 Diabetes Mellitus

India
University Hospital, Gentofte, Copenhagen

Completed

Effect of GIP After a Meal in Patients With Type 2 Diabetes (GA-7)

Type2 Diabetes

Denmark
King's College London

Recruiting

Glucagon-like Peptide 1 (GLP1) Receptor Agonists and Mental Health

Obesity | Diabetes Mellitus | Mental Health Issue

United Kingdom
Azienda Ospedaliero-Universitaria Consorziale Policlinico...

Completed

Efficacy of Glucagon-like Peptide-1 Receptor Agonists According to Type 2 Diabetes Subtypes

Diabetes Mellitus, Type 2

Italy
Turku University Hospital
Lund University

Completed

Splanchnic Blood Redistribution After Incretin Hormone Infusion and Obesity Surgery (GIP-PET)

Obesity | Type 2 Diabetes

Finland
Centre Hospitalier Universitaire Dijon

Completed

Effects of GLP-1 Agonists on CArdiac Steatosis Evaluated by Magnetic Resonance Imaging (LICAS-MR)

Type II Diabetes

France
Jose Seijas Amigo

Completed

SEMAGLUTIDE VERSUS GLP-1 RECEPTOR AGONISTS. EFFECTIVENESS , SAFETY AND QUALITY OF LIFE IN PATIENTS WITH DIABETES MELLITUS 2. OBSERVATIONAL, PROSPECTIVE AND MULTICENTER STUDY. SEVERAL STUDY. (SEVERAL)

Quality of Life | Diabetes Mellitus, Type 2 | Weight Loss | Safety Issues

Spain
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Effect of Gene Polymorphisms on GLP-1 Receptor Agonists Response in Patients With T2DM

Type 2 Diabetes Mellitus

China
Ludwig-Maximilians - University of Munich
German Research Foundation; Merck Sharp & Dohme LLC

Completed

Exendin(9-39)Amide as a Glucagon-like Peptide-1 (GLP-1) Receptor Antagonist in Humans

Hyperglycemia

Germany
University of Copenhagen
Hvidovre University Hospital

Completed

Effects of Gut Peptides on Bone Remodeling. KS-4-Diabetes-19

Type 2 Diabetes Mellitus

Denmark
Hvidovre University Hospital
University of Copenhagen

Completed

Effect of RYGB on Alpha- and Beta Cell Function and Sensitivity to Incretins in Patients With Type 2 Diabetes (BETASIN)

Obesity, Morbid | Type2 Diabetes

Denmark
University of Copenhagen
Hvidovre University Hospital

Completed

Effects of Gut Peptides on Bone Remodeling (KS-3)

Healthy

Denmark
Zealand Pharma

Completed

A Multiple Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Healthy

Germany
University Hospital Tuebingen
Merck Sharp & Dohme LLC

Withdrawn

Characterization of Beta Cell Failure

Diabetes | Metabolic Syndrome

Germany
Southern Illinois University Edwardsville

Terminated

Effects of Resistance Training on Substrate Metabolism During the Menstrual Cycle

Menstrual Cycle | Substrate Metabolism

United States
Southern Illinois University Edwardsville

Terminated

Effects of Resistance Training in Body Composition and Body Image Perception of Women Throughout the Menstrual Cycle

Body Image Disturbance

United States
Indiana University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Modulation of Human Myocardial Metabolism by GLP-1 Dose Response

Healthy | Type 2 Diabetes Mellitus

United States
Dr Adnan Agha

Recruiting

Effect on Non-Alcoholic Fatty Liver Disease in Patients With Type 2 Diabetes Mellitus With Gastric Inhibitory Polypeptide/Glucagon Like Peptide-1 Analogue

Liver Fat | Type 2 Diabetes | Non-Alcoholic Fatty Liver Disease | Non-alcoholic Steatohepatitis

United Arab Emirates
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

Treating PCOS With Semaglutide vs Active Lifestyle Intervention (TEAL)

PCOS | NAFLD | Adolescent Obesity

United States
University of Copenhagen
Hvidovre University Hospital

Completed

Investigation of GLP-2 Mechanism of Action (GA-8)

Healthy

Denmark
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Association of Gene Polymorphism With Susceptibility to T2DM and the Therapeutic Responses to Exenatide in Chinese Patients With T2DM

Type 2 Diabetes Mellitus | Susceptibility, Genetic

China
University of Surrey
Sanofi

Completed

Lixisenatide-The Effects on Glucose and Lipid Metabolism in Type 2 Diabetes

Type 2 Diabetes

United Kingdom
Christina Kruuse

Recruiting

The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Stroke (EGRABIS1)

Ischemic Stroke

Denmark
Mayo Clinic
Merck Sharp & Dohme LLC

Completed

GLP1R Polymorphisms and Response to GLP1

Diabetes

United States
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Completed

The Effects of GIP and GLP-2 on the Secretion of Glucagon in Patients With Type 1 Diabetes

Diabetes Mellitus

Denmark
University of Chicago

Completed

Incretin Regulation of Insulin Secretion in Monogenic Diabetes

Monogenic Diabetes

United States
University of Copenhagen
Hvidovre University Hospital

Completed

Effects of a Liquid Meal and Gut Hormones (GIP and GLP-2) on Bone Remodeling in Participants With Hypoparathyroidism. (KS-4-HypoPT)

Hypoparathyroidism

Denmark
PegBio Co., Ltd.

Completed

Safety and Efficacy of Pegylated Exenatine Injection (PB-119) in Drug-naïve T2DM Subjects (PB119)

Type 2 Diabetes Mellitus (T2DM)

China
PegBio Co., Ltd.

Completed

Safety and Efficacy of PB-119 in Subjects With Type 2 Diabetes and Not Well-controlled by Metformin Monotherapy

Type 2 Diabetes Mellitus (T2DM)

China
Papworth Hospital NHS Foundation Trust

Completed

Human Vasodilatory Effect of GLP-1

Angina, Stable | Type2 Diabetes | Coronary Stenosis
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Completed

Glucagon-Like Peptide-1 (GLP-1) Suppression of Alpha Cell Secretion in Type 2 Diabetes Mellitus (T2DM)

Hyperglycemia | Glucose Intolerance | Hyperglucagonemia
Aarhus University Hospital Skejby
Aarhus University Hospital; University of Aarhus

Completed

Effect of 48 Hours of Treatment With the Natural Peptide-Hormone GLP-1 in Patients With Chronic Heart Failure

Heart Failure, Congestive

Denmark
University of Copenhagen
The Danish Medical Research Council

Completed

The Interaction Between Appetite Hormones

Obesity

Denmark

Search clinical trials for: GLP-1 agonists

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