Search clinical trials for: GLPG0259 solution

Total 19286 results

Mutual Pharmaceutical Company, Inc.

Completed

Drug - Drug Interaction Study Between Quinine Sulfate and Theophylline

Pharmacokinetics

United States
Medical University of Lublin

Not yet recruiting

Lumbar ESPB in Hip Replacement Surgery (ESPB_HIP)

Quality of Life | Pain, Postoperative | Analgesia | Pain, Acute | Anesthesia | Pain, Chronic | Postoperative Pain, Chronic | Coxarthrosis | Spinal

Poland
Peking University Third Hospital
Beijing Friendship Hospital; West China Hospital; The Affiliated Hospital of... and other collaborators

Recruiting

Study of Sumatriptan Naproxen Sodium Succinate Tablets for the Treatment of Acute Migraine Attacks

Migraine in Adults

China
Peking University

Recruiting

The Effectiveness and Safety of FK-506 for the Treatment of Posner-Schlossman Syndrome

Posner Schlossman Syndrome

China
Tiva Group

Completed

Morphine Consumption in the Obese Patients

Anesthesia Morbidity | Obesity, Morbid | Opioid Use | Post Operative Pain | Pharmacological Action

Spain
Thomas Chester, OD

Completed

Comparing Treatment of Dry Eye With Intracanalicular Dexamethasone, Restasis, and/or Lotemax

Dry Eye

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study on a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Compared to a Meningococcal Reference Vaccine, and When Given Alone or With Two Other Vaccines in Healthy Adolescents

Healthy Volunteers | Meningococcal Immunisation

Spain, Hungary, Italy, Singapore
GWT-TUD GmbH
AstraZeneca; Celgene

Active, not recruiting

Safety and Tolerance of Epigenetic and Immunomodulating Drugs Combined With Chemotherapeutics in Patients Suffering From Advanced Pancreatic Cancer (SEPION)

Pancreatic Adenocarcinoma | Pancreatic Ductal Adenocarcinoma | Pancreas Cancer

Germany
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Completed

An Open-Label, Randomized, Phase 3 Trial of Nivolumab Versus Investigator's Choice Chemotherapy as First-Line Therapy for Stage IV or Recurrent PD-L1+ Non-Small Cell Lung Cancer (CheckMate 026)

Stage IV or Recurrent Non-Small Cell Lung Cancer

United States, Finland, Argentina, France, Italy, Brazil, Greece, Japan, Mexico, Romania, Spain, Sweden, United Kingdom, Australia, Austria, Belgium, Canada, Czechia, Germany, Hungary, Korea, Republic of, Netherlands, Poland, Switzerland and more
University of Florida
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Delineating Swallowing Impairment and Decline in ALS

Amyotrophic Lateral Sclerosis

United States
Mansoura University

Completed

Adding Magnesium Sulfate to Bupivacaine in Ultrasound Guided Paravertebral Block for Laparoscopic Cholecystectomy

Laparoscopic Cholecystectomy

Egypt
Merz Pharmaceuticals GmbH

Completed

Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Arm(s) or of Arm(s) and Leg(s) in Cerebral Palsy (XARA)

Cerebral Palsy | Spasticity

Poland, Russian Federation, Ukraine, United States, Argentina, Mexico
Assiut University

Completed

Evaluation of Corticosteroid in Systemic Inflammatory Response Syndrome

Systemic Inflammatory Response Syndrome

Egypt
Shire

Completed

Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema (HAE) (FAST2)

Hereditary Angioedema

Italy
Institute for Mother and Child Health Care of Serbia...

Completed

Levobupivacaine and Postoperative Pain Relief

Postoperative Pain | Inguinal Hernia Unilateral

Serbia
Novartis Vaccines

Completed

Safety and Immunogenicity of Different Meningitis Vaccine Formulations in Adolescents and Young Adults

Invasive Meningococcal Disease

United States, Poland
New England Retina Associates
Ocular Therapeutix

Unknown

Evaluation of DEXTENZA in the Management of Pain and Inflammation in Patients With Anterior Uveitis Compared to Standard of Care Topical Corticosteroids (DiverT)

Non-infectious Anterior Uveitis
Bristol-Myers Squibb

Completed

Study to Evaluate Safety & Tolerability of BMS-906024 in Combination With Chemotherapy & to Define DLTs & MTD of BMS-906024 in Combination With One of the Following Chemotherapy Regimens; Weekly Paclitaxel, 5FU+Irinotecan or Carboplatin+Paclitaxel in Subjects With Advanced / Metastatic Solid Tumors

Cancer

United States, Canada, Belgium
Zhongshan Ophthalmic Center, Sun Yat-sen University

Completed

Effect of Bromfenac on Pain Related to Pterygium Surgery

Pain | Pterygium

China
Xiangya Hospital of Central South University

Completed

Hepatic Artery Infusion Pump for NPC Liver Metastases

Nasopharyngeal Carcinoma | Neoplasm Metastasis | Liver
Tariq Yehia

Completed

Efficiency of Triple Antibiotic Paste, Ciprofloxacin/Propolis, Ciprofloxacin/Metronidazole, Propolis/Metronidazole Combinations on Revascularization Process of Immature Necrotic Maxillary Incisors of Patients 8-18 Years Old.

Dental Pulp Necrosis | Root Canal Infection | Periapical Abscess
University of Alabama at Birmingham
Genentech, Inc.

Completed

Lower Dose Chemotherapy Given More Frequent With Avastin to Treat Advanced Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

United States
Brigham and Women's Hospital

Completed

Oxytocin And Uterotonic Agent Use For Cesarean Delivery

Hypotension | Uterine Atony

United States
Hospital General Naval de Alta Especialidad - Escuela...

Unknown

Epinephrine, Dexamethasone and Hypertonic Saline in Bronchiolitis

Bronchiolitis

Mexico
National Institute of Allergy and Infectious Diseases...
Asthma and Allergic Diseases Cooperative Research Centers

Terminated

Human Rhinovirus Infection and Airway Remodeling Mediators

Asthma

Canada
University of Colorado, Denver
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Mediators of Abnormal Reproductive Function in Obesity (MARO) (MARO)

Obesity | Infertility, Female

United States
Campus Bio-Medico University

Completed

Painless Local Infiltration Anesthesia (EASE)

Pain | Surgery | Varicose Veins | Anesthesia

Italy
Bp Consulting, Inc

Completed

Comparing Optical Coherence Tomography (OCT) and Visual Acuity Outcomes in Subjects Undergoing Cataract Surgery, Who Receive Xibrom Ophthalmic Solution and Standard Presurgical Care vs. Xibrom Ophthalmic Solution Plus Prednisolone Acetate 1% and Standard Presurgical Care

Cataracts

United States
University Medicine Greifswald

Completed

Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects

Hypercholesterolemia | Pharmacokinetics | Immunosuppression | Drug Interactions

Germany
Zagazig University

Completed

Evidence Based Management of Acute Biliary Pancreatitis

Acute Pancreatitis

Egypt
University of Roma La Sapienza

Unknown

Effect of Allopurinol on Mono and Co-administration With Statins on Platelets Reactivity on Diabetic Patiets Treated With Aspirin and Insulin

Diabetes Mellitus Type 2 Platelets Reactivity Statin

Italy
CMC Ambroise Paré

Not yet recruiting

WALANT Versus Axillary Brachial Plexus Block in Carpal Tunnel Release (WALAB)

Carpal Tunnel Syndrome

France
Dizal Pharmaceuticals

Recruiting

Assessing the Effect of DZD9008 on the Pharmacokinetics of the Cocktail Probes Representative for CYP3A4, P-gp, BCRP and OATP1B1 in Patients With EGFR or HER2 Mutant Advanced Non-small Cell Lung Cancer (WU-KONG19)

Non-small Cell Lung Cancer

China
University of California, San Francisco
Research to Prevent Blindness

Active, not recruiting

Parasitic Ulcer Treatment Trial Pilot

Acanthamoeba Keratitis

India
Takeda

Completed

A Study of Soticlestat With Itraconazole and Mefenamic Acid in Healthy Adults

Healthy Volunteers

United States
University at Buffalo
The VA Western New York Healthcare System

Completed

Optimal Timing of Intercostal Nerve Blocks During Video-Assisted Thoracic Surgeries

Video-Assisted Thoracic Surgery | Video-Assisted Thoracoscopic Surgery

United States
Mogilev Regional Clinical Hospital

Completed

Sciatic Nerve Blockade by Subgluteal Access 12.5 ml of 1% Lidocaine: US Guidance Versus US Guidance With Electrical Stimulation of Peripheral Nerves (Influence of the Sciatic Nerve Blockade on the Effectiveness of Small Doses of Local Anesthetic.). (EPBwEPN)

Ultrasonography | Sciatic Nerve | Nerve Block | Efficiency | Minimum Effective Dose

Belarus
Sanofi

Completed

Comparison of Two Treatment Regimens in Patients With Type 2 Diabetes After Short-term Intensive Insulin Therapy (SWITCH)

Type 2 Diabetes Mellitus

China
Sanofi

Completed

A Trial of Caplacizumab in Japanese Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP)

Thrombotic Thrombocytopenic Purpura

Japan
Baxalta now part of Shire

Completed

Tolerability and Safety of Immune Globulin Subcutaneous Solution (IGSC) and rHuPH20 in PID

Primary Immunodeficiency Diseases (PID)

United States
Nourhan M.Aly
Alexandria University

Completed

Nebulized Midazolam, Dexmedetomidine, and Their Combination in Sedation of Preschoolers Undergoing Dental Treatment

Dental Anxiety

Egypt
Beijing Tiantan Hospital

Unknown

Effects of Pre-emptive Scalp Infiltration With Ketorolac and Ropivacaine for Post-craniotomy Pain

Pain | Supratentorial Brain Tumor
Boehringer Ingelheim

Completed

Effectiveness of Two Different Doses of BI 1026706 on the Overall Peak-to-Peak (PtP) N2/P2-component Amplitude of Laser (Somatosensory, Radiant-heat) Evoked Potentials (LEP) in UVB(Ultraviolet)-Irradiated Skin in Healthy Male Volunteers

Healthy

Germany
St. Olavs Hospital

Completed

The Effect of Topical Administration of Common Drugs on Postoperative Bleeding and Pain

Pain, Postoperative | Postoperative Hemorrhage

Norway
Millennium Pharmaceuticals, Inc.

Completed

Effects of Fluconazole and Itraconazole CYP3A-Mediated Inhibition on the Pharmacokinetics, Safety, and Tolerability of MLN4924 in Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States
Palo Alto Medical Foundation

Completed

To Study the Effectiveness and Safety of Niacin and a Topical Steroid Eye Drop to Treat Retinal Vein Occlusions

Retinal Vein Occlusion

United States
Sanofi
Regeneron Pharmaceuticals

Completed

A Study Assessing the Safety and Efficacy of Sarilumab Added to Non-MTX DMARDs or as Monotherapy in Japanese Patients With Active Rheumatoid Arthritis (SARIL-RA-HARUKA)

Rheumatoid Arthritis

Japan
Medical University of Silesia
Silesian University of Medicine

Completed

SPI-directed Analgesia for Vitreoretinal Surgeries (SPIVS)

Postoperative Pain | Postoperative Nausea and Vomiting | Vitreoretinal Surgeries

Poland
Sanofi
Regeneron Pharmaceuticals

Terminated

Effect of SAR153191 (REGN88) With Methotrexate in Patients With Active Rheumatoid Arthritis Who Failed TNF-α Blockers

Rheumatoid Arthritis

United States, Italy, Mexico, Colombia, Czechia, Spain
Bristol-Myers Squibb
AbbVie

Completed

Study of Elotuzumab in Combination With Lenalidomide and Dexamethasone in Subjects With Multiple Myeloma and Various Levels of Renal Function

Multiple Myeloma

United States

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