Search clinical trials for: HIV Protease Inhibitors

Total 69673 results

Abbott

Completed

Special Investigation of Kaletra in Pregnant Women

Human Immunodeficiency Virus

Japan
Abbott

Completed

Evaluation of Kaletra Therapy Over the Long-term

Human Immunodeficiency Virus

Germany
Bristol-Myers Squibb

Completed

Study of a New Protease Inhibitor, BMS-232632, in Combination With Other Anti-HIV Drugs

HIV Infections

United States, Canada
Arribas, Jose R., M.D.
Abbott; Pulido, Federico, M.D.

Completed

"OK 2004 Study" (Only Kaletra 2004 Study): Study to Evaluate Suspending Nucleosides From Triple-Drug Therapy in HIV Subjects

HIV Infection

Spain
Bristol-Myers Squibb

Completed

A Comparison of Two Anti-HIV Triple-Drug Combinations in HIV-Infected Patients

HIV Infections

United States, Puerto Rico
Pharmacia and Upjohn

Completed

Safety and Effectiveness of Giving Combinations of Three or Four Anti-HIV Drugs to HIV-Infected Patients

HIV Infections

United States
Kirby Institute
Merck Sharp & Dohme LLC; amfAR, The Foundation for AIDS Research; Abbott

Completed

A Trial of 2 Options for Second Line Combination Antiretroviral Therapy Following Virological Failure of a Standard Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI)+2N(t)RTI First Line Regimen (SECOND-LINE)

HIV Infections

Taiwan, Australia, Argentina, Singapore, India, France, South Africa, Chile, Germany, Hong Kong, Ireland, Malaysia, Mexico, New Zealand, Nigeria, Peru, United Kingdom
Pfizer

Withdrawn

A Study to Learn About the Patients With COVID-19 Prescribed Paxlovid in Morocco

COVID-19 Drug Treatment
National Institute of Diabetes and Digestive and...

Completed

Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda Interferon

Hepatitis D | Liver Disease

United States
Epicentre
Université Abdou Moumouni; Centre de Recherche Médicale et Sanitaire; Ministry...

Withdrawn

Evaluation of Additional Treatments for COVID-19: a Randomized Trial in Niger (TRASCOV)

Covid-19
Radboud University Medical Center

Completed

Pharmacokinetic Study of Two Generic Co-formulations of Lopinavir/Ritonavir for HIV Infected Children (SURF) (SURF)

HIV Infections

Netherlands
Assiut University
Sohag University; South Valley University

Completed

Comparative Study of Two Regiemns in Management of Sofosbuvir/Daclatasvir Failure

HCV Coinfection

Egypt
Boehringer Ingelheim

Completed

Bioequivalence of Two Different Oral Solutions Tipranavir Administered in Combination With Ritonavir to Healthy Volunteers

Healthy
ViiV Healthcare
GlaxoSmithKline

Completed

A Simplification Study of Unboosted Reyataz With Epzicom (ASSURE) (ASSURE)

Infection, Human Immunodeficiency Virus

United States, Puerto Rico
Hospital Authority, Hong Kong

Unknown

A Multi-centre, Double-blinded, Randomized, Placebo-controlled Trial on the Efficacy and Safety of Lopinavir / Ritonavir Plus Ribavirin in the Treatment of Severe Acute Respiratory Syndrome

Severe Acute Respiratory Syndrome

China
Bristol-Myers Squibb

Completed

A Comparison of Two Triple-Drug Combinations in Patients Who Have Never Been Treated With Anti-HIV Drugs

HIV Infections

United States
Bristol-Myers Squibb

Completed

A Pilot Open Label Trial of HIV Therapy With d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects With Recent HIV Infection

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Effectiveness of Anti-HIV Drugs in Patients Who Have Not Received Previous Anti-HIV Drugs During Different Stages of HIV Infection

HIV Infections

United States
International Antiviral Therapy Evaluation Center
Gilead Sciences; Hoffmann-La Roche

Completed

BASIC: Boosted Atazanavir or Saquinavir Induced Lipid Changes

HIV Infections

Netherlands
Bristol-Myers Squibb

Completed

A Phase IIIb Study Comparing Two Boosted Protease Inhibitor-based HAART Regimens in HIV-infected Patients Experiencing Their First Virologic Failure While Receiving an NNRTI-containing HAART Regimen

HIV Infections

United States, Puerto Rico
Bristol-Myers Squibb

Completed

Induction-Maintenance With Atazanavir in HIV Naïve Patients (The INDUMA Study) (INDUMA)

HIV Infections

Spain, Italy, United Kingdom, France, Russian Federation, Ireland, Germany, Latvia, Estonia, Portugal
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Fortovase (Saquinavir) Given With Low-Dose Ritonavir, Zidovudine, and Lamivudine to HIV-Positive Pregnant Women During and After Pregnancy and to Their Newborns

HIV Infections | Pregnancy

United States, Puerto Rico
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

Enfuvirtide/Current Protease Inhibitor Switch to PREZISTA (Darunavir)/Ritonavir + TMC125 in HIV Patients With Enfuvirtide Side Effects.

HIV

United States
French National Agency for Research on AIDS and...
Bristol-Myers Squibb; Gilead Sciences

Terminated

Efficacy and Safety of Tenofovir DF/Atazanavir Enhanced With Low Dose of Ritonavir in HIV-Infected Patients

HIV Infections

France
French National Agency for Research on AIDS and...
Merck Sharp & Dohme LLC; Janssen-Cilag Tibotec

Completed

Clinical Trial to Assess the Efficacy of Darunavir/Ritonavir (DRV/r), Etravirine (ETV) and Raltegravir (MK-0518) in HIV Patients With Resistant Viruses (ANRS139 TRIO)

HIV Infections

France
University of Chicago
Abbott

Completed

A Research Study to See if a Change in Therapy for HIV Infection Can Improve the Immune Response to Treatment

HIV Infections

United States
Rockefeller University
Merck Sharp & Dohme LLC; Pfizer; Aaron Diamond AIDS Research Center

Completed

Standard Antiretroviral v. Multi-class Therapy in Acutely HIV-1 Infected Antiretroviral-Naïve Subjects (ADARC 2007-01)

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

A Study of Indinavir Plus Ritonavir Plus Two NRTIs vs. Nelfinavir Plus Two NRTIs in HIV Positive Patients (0639-112)(COMPLETED)

HIV Infections
Pfizer

Completed

A Study to Learn About PAXLOVID (a Commercial Medicine) In People With COVID-19

SARS-CoV-2 Infection

Japan
China National Center for Cardiovascular Diseases

Active, not recruiting

Prophylactic Effect of Nirmatrelvir/Ritonavir and Ursodeoxycholic Acid on Reducing Complications After Cardiac Surgery (PEP)

Cardiac Surgery

China
University of California, San Diego
Abbott

Completed

A Multicenter Study to Assess the Tolerability of Once Daily Lopinavir/Ritonavir (LPV/r) Liquid Versus Capsules

HIV Infection

United States
Fabrizio Cantini

Completed

Baricitinib Therapy in COVID-19

Pneumonia | COVID

Italy
National Institutes of Health Clinical Center (CC)

Completed

The Influence of Ritonavir, Alone and in Combination With Lopinavir, on Fenofibric Acid Pharmacokinetics in Healthy Volunteers

HIV | Hypertriglyceridemia | Fenofibrate | Protease Inhibitors | Glucuronosyltransferase

United States
Bristol-Myers Squibb

Completed

Phase IIIB Study Evaluating the Effects of Atazanavir Powder With Ritonavir in HIV-infected Pediatric Patients (PRINCE2)

HIV

United States, Chile, Spain, South Africa, Mexico, Argentina, Poland, Brazil, Russian Federation, Romania, United Kingdom
Masonic Cancer Center, University of Minnesota
Susan G. Komen Breast Cancer Foundation

Completed

Ritonavir and Its Effects on Biomarkers in Women Undergoing Surgery for Newly Diagnosed Breast Cancer

Breast Cancer

United States
Hoffmann-La Roche

Completed

ANNAPURNA: A Study of The Combination of RO5466731, RO5190591, Ritonavir and Copegus (Ribavirin) With or Without RO5024048 in Patients With Chronic Hepatitis C Who Are Either Treatment-Naïve or Have Previously Experienced a Null Response to Interferon-Based Treatment

Hepatitis C, Chronic

United States, New Zealand, Germany, Australia, Poland
Bristol-Myers Squibb

Completed

Study Assessing the Effects of Darunavir/Ritonavir or Lopinavir/Ritonavir on the Pharmacokinetics of Daclatasvir in Healthy Participants

Hepatitis C

United States
Boehringer Ingelheim

Completed

Pharmacokinetic Interaction Between Tipranavir and BILR 355 BS Plus Ritonavir in Healthy Male Volunteers

Healthy
Bristol-Myers Squibb

Completed

Bioequivalence Study of Individual Atazanavir and Cobicistat Compared With Atazanavir in Fixed-dose Combination With Cobicistat (Atazanavir)

Human Immunodeficiency Virus Type 1 (HIV-1)

United States
Fundacion SEIMC-GESIDA
Abbott

Completed

Lopinavir/r Monotherapy Versus Abacavir/Lamivudine and Lopinavir/r for Limb Fat Recovery in Persons With Lipoatrophy (KRETA)

HIV Infections | HIV Infection | Lipodystrophy

Spain
Bristol-Myers Squibb

Completed

A Pilot Open Label Trial of HIV Therapy With d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects With Early Asymptomatic HIV Infection

HIV Infections

United States
Gilead Sciences

Completed

The Safety and Effectiveness of Adefovir Dipivoxil Plus Indinavir Combined With Zidovudine or Lamivudine or Stavudine in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
Glaxo Wellcome

Completed

A Study of the Effects of Amprenavir, a Protease Inhibitor, on Carbohydrate and Fat Metabolism in HIV-Infected Patients

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study of HIV-Disease Development in Aging

HIV Infections

United States, Puerto Rico
University of North Carolina, Chapel Hill
Janssen Pharmaceuticals

Terminated

HIV Viremia and Persistence in Acutely HIV-Infected Patients Treated With Darunavir/Ritonavir and Etravirine

HIV Infections | Acute HIV Infection

United States
St Stephens Aids Trust

Completed

A Phase IV, Open-label Single-arm Study Investigating the Pharmacokinetics and Pharmacodynamics of the Antiretroviral Combination of Rilpivirine and Ritonavirboosted Darunavir in Therapy-naive HIV-1 Infected Patients.

HIV

United Kingdom
Boehringer Ingelheim

Completed

Pharmacokinetic of Tadalafil Co-administered With Tipranavir/Ritonavir to Healthy Male Volunteers

Healthy
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-TiDP2-C197: A Phase I Trial to Investigate the Pharmacokinetic Interaction Between Lopinavir/Ritonavir and TMC125 Both at Steady-state in Healthy Volunteers.

HIV
Hoffmann-La Roche

Completed

Comparison of Ro 31-8959 Plus Zidovudine (AZT) Versus AZT Plus Zalcitabine (ddC) Versus Ro 31-8959 Plus AZT Plus ddC

HIV Infections

United States
French National Agency for Research on AIDS and...

Terminated

Efficacy and Tolerability of an Antiretroviral Bi-Therapy in HIV Infected Patients With Multidrug Resistance

HIV Infections

France

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