Search clinical trials for: High-dose treatment

Total 21518 results

KBio Inc

Completed

Study to Evaluate the Safety and Immunogenicity of KBP-V001 Quadrivalent Influenza Vaccine in Healthy Adults

Influenza

United States
Alkermes, Inc.

Completed

A Study of ALKS 9072 in Subjects With Chronic Stable Schizophrenia

Schizophrenia

United States
Mitsubishi Tanabe Pharma Corporation

Completed

Study to Assess the Efficacy, Safety and Tolerability of MT- 8554 in Subjects With Painful Diabetic Peripheral Neuropathy

Painful Diabetic Peripheral Neuropathy

Germany, Hungary, Poland
Universidad Católica San Antonio de Murcia

Not yet recruiting

Blood Bioavailability of Two Different Doses of a β-alanine Supplement (BIo-β) (Bio-β)

Bioavailability

Spain
Amicus Therapeutics

Active, not recruiting

Gene Therapy for Children With CLN3 Batten Disease

Batten Disease | CLN3

United States
The University of Texas Health Science Center,...
National Center for Advancing Translational Sciences (NCATS)

Completed

Reducing Anticholinergic Bladder Medication Use in Spinal Cord Injury With Home Neuromodulation (TTNS-RCT)

Chronic Spinal Cord Injury | Neurogenic Bladder

United States
Mitsubishi Tanabe Pharma America Inc.

Completed

Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Erythropoietic Protoporphyria or X-Linked Protoporphyria

EPP | XLP

Spain, United States, Germany, Norway, Italy, Australia, Canada, Japan, Sweden, United Kingdom
Riphah International University

Completed

Dose Response of Neural Mobilization on Hamstring Flexibility in Low Back Pain

Non-specific Low Back Pain

Pakistan
Mount Sinai Hospital, Canada

Completed

A Pilot Study to Assess the Immunogenicity and Reactogenicity of High Versus Standard Dose TIV

Influenza

Canada
Genocea Biosciences, Inc.

Completed

Safety and Immunogenicity Study of Prophylactic Streptococcus Pneumoniae Vaccine

Streptococcus Pneumoniae

United States
Jonsson Comprehensive Cancer Center

Recruiting

High Dose-Rate Brachytherapy and Stereotactic Body Radiotherapy for the Treatment of Prostate Adenocarcinoma (HYDRA)

Prostate Adenocarcinoma | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Stage IIB Prostate Cancer American Joint Committee on...

United States
Boehringer Ingelheim

Completed

Weekly Intravenous Administrations of BI 836845 in Japanese Patients With Advanced Solid Tumours

Neoplasms

Japan
Pfizer
Thrombolysis In Myocardial Infarction (TIMI)

Recruiting

A Study of Ponsegromab in People With Heart Failure (GARDEN TIMI 74)

Heart Failure

United States, Canada, China, Australia, Spain, Japan, Czechia, Hungary, Germany, United Kingdom, Poland
Kolon TissueGene, Inc.

Not yet recruiting

Study to Determine the Safety and Tolerability of TG-C in Subjects With Back Pain Due to Degenerative Disc Disease

Degenerative Disc Disease
Weill Medical College of Cornell University

Recruiting

Cryopreservation of Ovarian Tissue

Cancer | Fertility Preservation | Risk of Premature Ovarian Failure

United States
Beacon Therapeutics

Enrolling by invitation

A Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (DAWN)

X-Linked Retinitis Pigmentosa

United States
Jiangsu Province Centers for Disease Control and...
Beijing Institute of Biotechnology; Tianjin Cansino Biotechnology Inc

Completed

A Phase I Clinical Trial to Evaluate the Ebola Adenovirus Vector Vaccine (Ad5-EBOV) in Healthy Adults.

Ebola Virus Disease

China
Jiangsu Province Centers for Disease Control and...
West China Hospital

Completed

A Phase Ⅱ Clinical Trial of Recombinant Corona Virus Disease-19 (COVID-19) Vaccine (Sf9 Cells)

COVID-19

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Safety and Efficacy Study of SHR4640 and Febuxostat in Subjects With Hyperuricemia

Hyperuricemia
Iowa State University
National Institute of Mental Health (NIMH)

Recruiting

RESISTance Exercise for Depression Trial (RESIST)

Major Depressive Disorder

United States
Morten Hostrup, PhD

Recruiting

U-LABA/ICS Effects on Exercise Performance, Indacaterol

Exercise Performance

Denmark
Greenyn Biotechnology Co., Ltd.
Taipei Medical University

Recruiting

Effectiveness of Pumpkin Seed Extract on Improving Blood Sugar Level in Subhealth Subjects

Diabetes | Metabolic Disease

Taiwan
Hebrew University of Jerusalem
aMoon fund

Completed

Examining the Effectiveness of a Tablet Video Game on Mood and Cognition (THRIVE)

Depressive Symptoms | Mood Disturbance

Israel
AxeroVision, Inc.

Completed

Evaluation of AXR-270 for the Treatment of Posterior Blepharitis Associated With Meibomian Gland Dysfunction

Meibomian Gland Dysfunction | Posterior Blepharitis

United States
Anavex Life Sciences Corp.
Anavex Australia Pty Ltd.; Anavex Germany GmbH; Anavex Canada Ltd.

Completed

ANAVEX2-73 for Treatment of Early Alzheimer's Disease

Alzheimer Disease

Australia, Canada, Germany, Netherlands, United Kingdom
Anavex Life Sciences Corp.
Anavex Germany GmbH

Completed

ANAVEX2-73 Study in Parkinson's Disease Dementia

Parkinsons Disease With Dementia

Spain, Australia
Tianjin Medical University Cancer Institute and...

Unknown

Icotinib at Different Doses in Second-line Treatment for Non-small Cell Lung Cancer Patients With Wild Type EGFR

Non-small Cell Lung Cancer

China
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Study of High-Dose-Rate Endorectal Brachytherapy (HDRBT) in the Treatment of Locally Advanced Low Rectal Cancer (HDRBT)

Rectal Cancer

United States
AbbVie
Boehringer Ingelheim

Completed

Single Rising Dose Study of BI 655066 in Patients With Moderate and Severe Psoriasis

Psoriasis

United States, Germany, United Kingdom
Appalachian State University

Recruiting

Hemp Fiber Ingestion and Gut Permeability After Exercise

Gastrointestinal Dysfunction | Metabolic Disturbance

United States
Nobelpharma

Completed

A Study for Kidney Transplant Recipients at High-Risk of Cytomegalovirus Infection

Cytomegalovirus Disease

United States, Japan
Visterra, Inc.
Biomedical Advanced Research and Development Authority

Completed

Study of an Investigational Monoclonal Antibody, VIS410, in Subjects With Uncomplicated Influenza A

Influenza

United States, Estonia, South Africa, Bulgaria, Serbia, Ukraine, Latvia
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of BIIL 284 BS in Adult and Pediatric Cystic Fibrosis (CF) Patients

Cystic Fibrosis
Boehringer Ingelheim

Terminated

Efficacy, Safety and Pharmacokinetics of BIRB 796 BS Tablets in Patients With Active Rheumatoid Arthritis

Arthritis, Rheumatoid
Boehringer Ingelheim

Completed

Safety and Pharmacokinetics of BIRB 796 BS Tablets Administered to Healthy Human Subjects

Healthy
OcuNexus Therapeutics, Inc.

Completed

A Study to Investigate the Efficacy, Safety and Tolerability of Nexagon® as a Topical Treatment for Subjects With Venous Leg Ulcers (NOVEL2)

Venous Leg Ulcers

United States, New Zealand, South Africa, Australia
Ariston Pharmaceuticals, Inc.

Unknown

Efficacy and Safety Clinical Trial of Intranasal AST-726 for the Prevention of Migraine

Migraine | Migraine Disorders | Migraine Headache | Migraine Without Aura | Migraine With Aura

Finland, Netherlands, United Kingdom
Seqirus
Novartis Vaccines

Completed

Safety, Tolerability, and Immunogenicity of Different Combinations of Trivalent Influenza Vaccine Varying Influenza Antigen Dose, Adjuvant Dose, and Route of Administration in Healthy Elderly Individuals Ages 65 Years and Older

Influenza

Belgium
Boehringer Ingelheim

Completed

BI 113608 Administered as Tablets Twice Daily Over 4 Weeks in Patients With Chronic Obstructive Pulmonary Disease Associated With Chronic Bronchitis

Pulmonary Disease, Chronic Obstructive

Germany
Centre Hospitalier Universitaire de Nīmes
Centre Hospitalier Lyon Sud; Hôpital Haut-Lévêque

Unknown

Pharmacokinetics of High-dose Ceftobiprole in Community-acquired Pneumonia Under Mechanical Ventilation. (PAC CEF)

Pneumonia

France
Centre Hospitalier Universitaire Vaudois

Recruiting

Irradiation of Melanoma in a Pulse (IMPulse)

Metastasis From Malignant Melanoma of Skin (Diagnosis)

Switzerland
Memorial Sloan Kettering Cancer Center

Completed

Image-Guided Navigation for High Dose Rate Temporary Interstitial Brachytherapy in the Palliative Management of Previously Treated Tumors of the Spine and Pelvis

Metastatic or Recurrent Lesions in the Spine | Metastatic or Recurrent Lesions in the Pelvis

United States
National Cancer Institute, Egypt

Recruiting

Low Dose Versus High Dose Methylene Blue in Septic Patients

Septic Shock

Egypt
First Affiliated Hospital Xi'an Jiaotong University
Eureka Therapeutics Inc.

Unknown

Clinical Study of ET019002-T Cell Therapy for Refractory/Relapsed B-Cell Malignancies

B-Cell Malignancies
OcuNexus Therapeutics, Inc.

Completed

A Study to Investigate the Safety and Clinical Effect of Nexagon® as a Topical Treatment for Subjects With a Diabetic Foot Ulcer (DUNE) (DUNE)

Diabetic Foot Ulcers

Russian Federation, United States, Ukraine
Lassen Therapeutics Inc.

Recruiting

A Study to Evaluate the Efficacy and Safety of LASN01 in Patients With Thyroid Eye Disease

Eye Diseases | Endocrine System Diseases | Thyroid Eye Disease | Graves Ophthalmopathy | Orbital Diseases | Thyroid Associated Ophthalmopathy | Graves Orbitopathy | Proptosis

United States, United Kingdom, Spain
Brand's Suntory Asia
Taipei Medical University Shuang Ho Hospital

Not yet recruiting

The Effects of Chicken Extract on Mental Energy in Healthy Adults and the Underlying Mechanisms

Healthy Adults

Taiwan
Vedic Lifesciences Pvt. Ltd.

Completed

A Study to Evaluate the Efficacy of E-PR-01 on Musculoskeletal Health in Physically Active Individuals

Joint Pain

India
Lowell Anthony, MD
TerSera Therapeutics LLC

Terminated

Telotristat With Lutathera in Neuroendocrine Tumors

Neuroendocrine Tumors

United States
RespireRx

Completed

CX717 in the Treatment of Adult ADHD

Attention Deficit Hyperactivity Disorder

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